Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 1821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-6 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM342166 ((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...) Show SMILES C[C@@H]1CNC(=O)c2cc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc3n12 |r| Show InChI InChI=1S/C23H21N5O2/c1-15-11-24-23(30)21-10-17-9-19(7-8-20(17)28(15)21)26-22(29)18-12-25-27(14-18)13-16-5-3-2-4-6-16/h2-10,12,14-15H,11,13H2,1H3,(H,24,30)(H,26,29)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-6 (Homo sapiens (Human))	BDBM342166 ((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...) Show SMILES C[C@@H]1CNC(=O)c2cc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc3n12 |r| Show InChI InChI=1S/C23H21N5O2/c1-15-11-24-23(30)21-10-17-9-19(7-8-20(17)28(15)21)26-22(29)18-12-25-27(14-18)13-16-5-3-2-4-6-16/h2-10,12,14-15H,11,13H2,1H3,(H,24,30)(H,26,29)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM342166 ((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...) Show SMILES C[C@@H]1CNC(=O)c2cc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc3n12 |r| Show InChI InChI=1S/C23H21N5O2/c1-15-11-24-23(30)21-10-17-9-19(7-8-20(17)28(15)21)26-22(29)18-12-25-27(14-18)13-16-5-3-2-4-6-16/h2-10,12,14-15H,11,13H2,1H3,(H,24,30)(H,26,29)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.6	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286087 (1-benzyl-N-(2-methyl-2,3,4,5-tetrahydro-1H-pyrido[...) Show SMILES CN1CCc2[nH]c3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)cc3c2C1 Show InChI InChI=1S/C23H23N5O/c1-27-10-9-22-20(15-27)19-11-18(7-8-21(19)26-22)25-23(29)17-12-24-28(14-17)13-16-5-3-2-4-6-16/h2-8,11-12,14,26H,9-10,13,15H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286086 (1-benzyl-N-(2-methyl-1,2,3,4-tetrahydrobenzofuro[3...) Show SMILES CN1CCc2oc3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)cc3c2C1 Show InChI InChI=1S/C23H22N4O2/c1-26-10-9-22-20(15-26)19-11-18(7-8-21(19)29-22)25-23(28)17-12-24-27(14-17)13-16-5-3-2-4-6-16/h2-8,11-12,14H,9-10,13,15H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286085 (1-benzyl-N-(1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a...) Show SMILES O=C(Nc1ccc2cc3C(=O)NCCn3c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C22H19N5O2/c28-21(17-12-24-26(14-17)13-15-4-2-1-3-5-15)25-18-7-6-16-10-20-22(29)23-8-9-27(20)19(16)11-18/h1-7,10-12,14H,8-9,13H2,(H,23,29)(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM342161 (1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-6-y...) Show SMILES O=C(Nc1ccc2c(CN3CCNCC3)csc2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H25N5OS/c30-24(19-13-26-29(16-19)14-18-4-2-1-3-5-18)27-21-6-7-22-20(17-31-23(22)12-21)15-28-10-8-25-9-11-28/h1-7,12-13,16-17,25H,8-11,14-15H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286075 (1-Benzyl-N-(3-(morpholinomethyl)-1H-indol-6-yl)-1H...) Show SMILES O=C(Nc1ccc2c(CN3CCOCC3)c[nH]c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H25N5O2/c30-24(20-14-26-29(17-20)15-18-4-2-1-3-5-18)27-21-6-7-22-19(13-25-23(22)12-21)16-28-8-10-31-11-9-28/h1-7,12-14,17,25H,8-11,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286081 (1-benzyl-N-(3-(morpholinomethyl)benzofuran-5-yl)-1...) Show SMILES O=C(Nc1ccc2occ(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O3/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-23-22(12-21)20(17-31-23)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286080 (1-benzyl-N-(3-(morpholinomethyl)benzofuran-6-yl)-1...) Show SMILES O=C(Nc1ccc2c(CN3CCOCC3)coc2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O3/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-22-20(17-31-23(22)12-21)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286074 (1-Benzyl-N-(3-(morpholinomethyl)-1H-indol-5-yl)-1H...) Show SMILES O=C(Nc1ccc2[nH]cc(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H25N5O2/c30-24(20-14-26-29(17-20)15-18-4-2-1-3-5-18)27-21-6-7-23-22(12-21)19(13-25-23)16-28-8-10-31-11-9-28/h1-7,12-14,17,25H,8-11,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286082 (1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-5-y...) Show SMILES O=C(Nc1ccc2occ(CN3CCNCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C29H33N5O4/c1-29(2,3)38-28(36)33-13-11-32(12-14-33)18-23-20-37-26-10-9-24(15-25(23)26)31-27(35)22-16-30-34(19-22)17-21-7-5-4-6-8-21/h4-10,15-16,19-20H,11-14,17-18H2,1-3H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286076 (1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...) Show SMILES CN1CCN(Cc2c[nH]c3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)cc23)CC1 Show InChI InChI=1S/C25H28N6O/c1-29-9-11-30(12-10-29)17-20-14-26-24-8-7-22(13-23(20)24)28-25(32)21-15-27-31(18-21)16-19-5-3-2-4-6-19/h2-8,13-15,18,26H,9-12,16-17H2,1H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286077 (1-Benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-...) Show SMILES CN1CCN(Cc2c[nH]c3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc23)CC1 Show InChI InChI=1S/C25H28N6O/c1-29-9-11-30(12-10-29)17-20-14-26-24-13-22(7-8-23(20)24)28-25(32)21-15-27-31(18-21)16-19-5-3-2-4-6-19/h2-8,13-15,18,26H,9-12,16-17H2,1H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286078 (1-Benzyl-N-(3-(morpholinomethyl)benzo[b]thiophen-5...) Show SMILES O=C(Nc1ccc2scc(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O2S/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-23-22(12-21)20(17-31-23)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286079 (1-Benzyl-N-(3-(piperazin-1-ylmethyl)benzo[b]thioph...) Show SMILES O=C(Nc1ccc2scc(CN3CCNCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C29H33N5O3S/c1-29(2,3)37-28(36)33-13-11-32(12-14-33)18-23-20-38-26-10-9-24(15-25(23)26)31-27(35)22-16-30-34(19-22)17-21-7-5-4-6-8-21/h4-10,15-16,19-20H,11-14,17-18H2,1-3H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286090 ((R)¿N-(1-(2-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2N)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-17-9-10-21(31-23(17)34(16)22)24(35)30-19-13-29-33(15-19)14-18-7-5-6-8-20(18)32-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,32,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286091 ((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccc(N)cc2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-7-10-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-5-8-19(9-6-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286089 ((R)¿N-(1-(3-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2cccc(N)c2)c1 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)22-11-18-8-9-21(32-23(18)34(16)22)24(35)30-20-13-29-33(15-20)14-17-6-5-7-19(10-17)31-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,35)(H,31,37)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM342166 ((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...) Show SMILES C[C@@H]1CNC(=O)c2cc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc3n12 |r| Show InChI InChI=1S/C23H21N5O2/c1-15-11-24-23(30)21-10-17-9-19(7-8-20(17)28(15)21)26-22(29)18-12-25-27(14-18)13-16-5-3-2-4-6-16/h2-10,12,14-15H,11,13H2,1H3,(H,24,30)(H,26,29)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286092 ((R)-1-(3-aminobenzyl)-N-(9-methyl-6-oxo-6,7,8,9-te...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(NC(=O)c4cnn(Cc5cccc(N)c5)c4)nc3n12 |r| Show InChI InChI=1S/C27H29N7O4/c1-16-12-28-25(36)21-11-18-8-9-22(31-23(18)34(16)21)32-24(35)19-13-29-33(15-19)14-17-6-5-7-20(10-17)30-26(37)38-27(2,3)4/h5-11,13,15-16H,12,14H2,1-4H3,(H,28,36)(H,30,37)(H,31,32,35)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286093 ((R)-9-methyl-N-(1-((1-methylpiperidin-4-yl)methyl)...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(CC2CCN(C)CC2)c1 |r| Show InChI InChI=1S/C22H27N7O2/c1-14-10-23-22(31)19-9-16-3-4-18(26-20(16)29(14)19)21(30)25-17-11-24-28(13-17)12-15-5-7-27(2)8-6-15/h3-4,9,11,13-15H,5-8,10,12H2,1-2H3,(H,23,31)(H,25,30)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286084 ((R)-1-benzyl-N-(4-methyl-1-oxo-1,2,3,4-tetrahydrop...) Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)cc3n12 |r| Show InChI InChI=1S/C18H23BrN2O4/c1-11(10-20-17(23)25-18(2,3)4)21-14-9-13(19)7-6-12(14)8-15(21)16(22)24-5/h6-9,11H,10H2,1-5H3,(H,20,23)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+6	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair