Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for entry = 1927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323669 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(C1)Oc1ccccc1 Show InChI InChI=1S/C27H30N4O4/c1-2-33-24-12-6-7-13-25(24)35-22-11-8-14-30(17-22)27-28-15-20(16-29-27)26(32)31-18-23(19-31)34-21-9-4-3-5-10-21/h3-7,9-10,12-13,15-16,22-23H,2,8,11,14,17-19H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323644 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C26H28N4O3/c1-2-32-23-11-5-6-12-24(23)33-22-10-7-13-29(18-22)26-27-14-21(15-28-26)25(31)30-16-19-8-3-4-9-20(19)17-30/h3-6,8-9,11-12,14-15,22H,2,7,10,13,16-18H2,1H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323668 (N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H]1CCc2ccccc12 Show InChI InChI=1S/C27H30N4O3/c1-2-33-24-11-5-6-12-25(24)34-21-9-7-15-31(18-21)27-28-16-20(17-29-27)26(32)30-23-14-13-19-8-3-4-10-22(19)23/h3-6,8,10-12,16-17,21,23H,2,7,9,13-15,18H2,1H3,(H,30,32)/t21-,23+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323626 (US10188653, Example 15 | US9789110, 15) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccc(cc1)C(C)C(O)=O |r| Show InChI InChI=1S/C28H32N4O5/c1-3-36-24-8-4-5-9-25(24)37-23-7-6-14-32(18-23)28-30-16-22(17-31-28)26(33)29-15-20-10-12-21(13-11-20)19(2)27(34)35/h4-5,8-13,16-17,19,23H,3,6-7,14-15,18H2,1-2H3,(H,29,33)(H,34,35)/t19?,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323638 ((R)-N-benzyl-2-(3-(2- ethoxyphenoxy)piperidin- 1-y...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H28N4O3/c1-2-31-22-12-6-7-13-23(22)32-21-11-8-14-29(18-21)25-27-16-20(17-28-25)24(30)26-15-19-9-4-3-5-10-19/h3-7,9-10,12-13,16-17,21H,2,8,11,14-15,18H2,1H3,(H,26,30)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323662 ((R)-(3,3-difluoroazetidin- 1-yl)(2-(3-(2- ethoxyph...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(F)(F)C1 Show InChI InChI=1S/C21H24F2N4O3/c1-2-29-17-7-3-4-8-18(17)30-16-6-5-9-26(12-16)20-24-10-15(11-25-20)19(28)27-13-21(22,23)14-27/h3-4,7-8,10-11,16H,2,5-6,9,12-14H2,1H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM276749 (US10188653, Example 19.21 | US11034678, WO20151406...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC(C)(C)CO |r| Show InChI InChI=1S/C22H30N4O4/c1-4-29-18-9-5-6-10-19(18)30-17-8-7-11-26(14-17)21-23-12-16(13-24-21)20(28)25-22(2,3)15-27/h5-6,9-10,12-13,17,27H,4,7-8,11,14-15H2,1-3H3,(H,25,28)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323602 (US10188653, Example 8 | US9789110, 8) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cc1F)C(=O)NCc1ccnc(c1)C(O)=O |r| Show InChI InChI=1S/C26H27FN4O5/c1-2-35-22-7-3-4-8-23(22)36-19-6-5-11-31(16-19)24-20(27)13-18(15-29-24)25(32)30-14-17-9-10-28-21(12-17)26(33)34/h3-4,7-10,12-13,15,19H,2,5-6,11,14,16H2,1H3,(H,30,32)(H,33,34)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323655 ((R)-N-cyclobutyl-2-(3-(2- ethoxyphenoxy)piperidin-...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC1CCC1 Show InChI InChI=1S/C22H28N4O3/c1-2-28-19-10-3-4-11-20(19)29-18-9-6-12-26(15-18)22-23-13-16(14-24-22)21(27)25-17-7-5-8-17/h3-4,10-11,13-14,17-18H,2,5-9,12,15H2,1H3,(H,25,27)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323634 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(iso...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccon1 Show InChI InChI=1S/C22H25N5O4/c1-2-29-19-7-3-4-8-20(19)31-18-6-5-10-27(15-18)22-24-12-16(13-25-22)21(28)23-14-17-9-11-30-26-17/h3-4,7-9,11-13,18H,2,5-6,10,14-15H2,1H3,(H,23,28)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323652 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(iso...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)Nc1ccon1 Show InChI InChI=1S/C21H23N5O4/c1-2-28-17-7-3-4-8-18(17)30-16-6-5-10-26(14-16)21-22-12-15(13-23-21)20(27)24-19-9-11-29-25-19/h3-4,7-9,11-13,16H,2,5-6,10,14H2,1H3,(H,24,25,27)/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323647 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(oxa...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cocn1 Show InChI InChI=1S/C22H25N5O4/c1-2-30-19-7-3-4-8-20(19)31-18-6-5-9-27(13-18)22-24-10-16(11-25-22)21(28)23-12-17-14-29-15-26-17/h3-4,7-8,10-11,14-15,18H,2,5-6,9,12-13H2,1H3,(H,23,28)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323649 ((R)-N-(4-amino-2-methyl- 4-oxobutan-2-yl)-2-(3-(2-...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NC(C)(C)CC(N)=O Show InChI InChI=1S/C23H31N5O4/c1-4-31-18-9-5-6-10-19(18)32-17-8-7-11-28(15-17)22-25-13-16(14-26-22)21(30)27-23(2,3)12-20(24)29/h5-6,9-10,13-14,17H,4,7-8,11-12,15H2,1-3H3,(H2,24,29)(H,27,30)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323640 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC(C1)OC Show InChI InChI=1S/C22H28N4O4/c1-3-29-19-8-4-5-9-20(19)30-17-7-6-10-25(13-17)22-23-11-16(12-24-22)21(27)26-14-18(15-26)28-2/h4-5,8-9,11-12,17-18H,3,6-7,10,13-15H2,1-2H3/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323667 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H30N4O3/c1-2-29-20-10-4-5-11-21(20)30-19-9-8-14-27(17-19)23-24-15-18(16-25-23)22(28)26-12-6-3-7-13-26/h4-5,10-11,15-16,19H,2-3,6-9,12-14,17H2,1H3/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323635 ((R)-N-(cyclopropylmethyl)- 2-(3-(2- ethoxyphenoxy)...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCC1CC1 Show InChI InChI=1S/C22H28N4O3/c1-2-28-19-7-3-4-8-20(19)29-18-6-5-11-26(15-18)22-24-13-17(14-25-22)21(27)23-12-16-9-10-16/h3-4,7-8,13-14,16,18H,2,5-6,9-12,15H2,1H3,(H,23,27)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323646 (((1R,4R)-2-oxa-5- azabicyclo[2.2.1]heptan-5- yl)(2...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1C[C@H]2C[C@@H]1CO2 Show InChI InChI=1S/C23H28N4O4/c1-2-29-20-7-3-4-8-21(20)31-18-6-5-9-26(13-18)23-24-11-16(12-25-23)22(28)27-14-19-10-17(27)15-30-19/h3-4,7-8,11-12,17-19H,2,5-6,9-10,13-15H2,1H3/t17-,18-,19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323650 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(pyr...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cnccn1 Show InChI InChI=1S/C23H26N6O3/c1-2-31-20-7-3-4-8-21(20)32-19-6-5-11-29(16-19)23-27-12-17(13-28-23)22(30)26-15-18-14-24-9-10-25-18/h3-4,7-10,12-14,19H,2,5-6,11,15-16H2,1H3,(H,26,30)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323632 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H28N4O4/c1-2-29-19-7-3-4-8-20(19)30-18-6-5-9-26(16-18)22-23-14-17(15-24-22)21(27)25-10-12-28-13-11-25/h3-4,7-8,14-15,18H,2,5-6,9-13,16H2,1H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323664 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CCCC1 Show InChI InChI=1S/C22H28N4O3/c1-2-28-19-9-3-4-10-20(19)29-18-8-7-13-26(16-18)22-23-14-17(15-24-22)21(27)25-11-5-6-12-25/h3-4,9-10,14-15,18H,2,5-8,11-13,16H2,1H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323643 ((R)-azetidin-1-yl(2-(3-(2- ethoxyphenoxy)piperidin...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CCC1 Show InChI InChI=1S/C21H26N4O3/c1-2-27-18-8-3-4-9-19(18)28-17-7-5-10-25(15-17)21-22-13-16(14-23-21)20(26)24-11-6-12-24/h3-4,8-9,13-14,17H,2,5-7,10-12,15H2,1H3/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323663 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(2-(...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCc1cn[nH]c1O Show InChI InChI=1S/C23H28N6O4/c1-2-32-19-7-3-4-8-20(19)33-18-6-5-11-29(15-18)23-25-12-17(13-26-23)21(30)24-10-9-16-14-27-28-22(16)31/h3-4,7-8,12-14,18H,2,5-6,9-11,15H2,1H3,(H,24,30)(H2,27,28,31)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323641 ((R)-N-(2-(1H-1,2,4-triazol- 1-yl)ethyl)-2-(3-(2- e...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCn1cncn1 Show InChI InChI=1S/C22H27N7O3/c1-2-31-19-7-3-4-8-20(19)32-18-6-5-10-28(14-18)22-25-12-17(13-26-22)21(30)24-9-11-29-16-23-15-27-29/h3-4,7-8,12-13,15-16,18H,2,5-6,9-11,14H2,1H3,(H,24,30)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323653 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(pyr...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)Nc1cncnc1 Show InChI InChI=1S/C22H24N6O3/c1-2-30-19-7-3-4-8-20(19)31-18-6-5-9-28(14-18)22-25-10-16(11-26-22)21(29)27-17-12-23-15-24-13-17/h3-4,7-8,10-13,15,18H,2,5-6,9,14H2,1H3,(H,27,29)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323637 ((R)-(2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimi...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1Cc2cnn(C)c2C1 Show InChI InChI=1S/C24H28N6O3/c1-3-32-21-8-4-5-9-22(21)33-19-7-6-10-29(15-19)24-25-11-17(12-26-24)23(31)30-14-18-13-27-28(2)20(18)16-30/h4-5,8-9,11-13,19H,3,6-7,10,14-16H2,1-2H3/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323595 (US10188653, Example 4 | US9789110, 4) Show SMILES CCNC(=O)c1cnc(nc1)N1CCC[C@H](C1)Oc1ccccc1OCC |r| Show InChI InChI=1S/C20H26N4O3/c1-3-21-19(25)15-12-22-20(23-13-15)24-11-7-8-16(14-24)27-18-10-6-5-9-17(18)26-4-2/h5-6,9-10,12-13,16H,3-4,7-8,11,14H2,1-2H3,(H,21,25)/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323612 (US10188653, Example 9 | US9789110, 9) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(ccc1C)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-8-4-5-9-24(23)36-22-7-6-12-31(17-22)27-29-15-21(16-30-27)25(32)28-14-20-13-19(26(33)34)11-10-18(20)2/h4-5,8-11,13,15-16,22H,3,6-7,12,14,17H2,1-2H3,(H,28,32)(H,33,34)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323624 (US10188653, Example 13 | US9789110, 13) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccc(cc1C)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-8-4-5-9-24(23)36-22-7-6-12-31(17-22)27-29-15-21(16-30-27)25(32)28-14-20-11-10-19(26(33)34)13-18(20)2/h4-5,8-11,13,15-16,22H,3,6-7,12,14,17H2,1-2H3,(H,28,32)(H,33,34)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323645 (2-((R)-3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((R...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H]1CNC(=O)C1 Show InChI InChI=1S/C22H27N5O4/c1-2-30-18-7-3-4-8-19(18)31-17-6-5-9-27(14-17)22-24-11-15(12-25-22)21(29)26-16-10-20(28)23-13-16/h3-4,7-8,11-12,16-17H,2,5-6,9-10,13-14H2,1H3,(H,23,28)(H,26,29)/t16-,17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323627 (US10188653, Example 16 | US9789110, 16) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(C)cc(c1)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-8-4-5-9-24(23)36-22-7-6-10-31(17-22)27-29-15-21(16-30-27)25(32)28-14-19-11-18(2)12-20(13-19)26(33)34/h4-5,8-9,11-13,15-16,22H,3,6-7,10,14,17H2,1-2H3,(H,28,32)(H,33,34)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323659 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(3-(...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCC(=O)NC Show InChI InChI=1S/C22H29N5O4/c1-3-30-18-8-4-5-9-19(18)31-17-7-6-12-27(15-17)22-25-13-16(14-26-22)21(29)24-11-10-20(28)23-2/h4-5,8-9,13-14,17H,3,6-7,10-12,15H2,1-2H3,(H,23,28)(H,24,29)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323623 (US10188653, Example 12 | US9789110, 12) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(cnc1C)C(O)=O |r| Show InChI InChI=1S/C26H29N5O5/c1-3-35-22-8-4-5-9-23(22)36-21-7-6-10-31(16-21)26-29-14-20(15-30-26)24(32)28-12-18-11-19(25(33)34)13-27-17(18)2/h4-5,8-9,11,13-15,21H,3,6-7,10,12,16H2,1-2H3,(H,28,32)(H,33,34)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323596 (US10188653, Example 5 | US9789110, 5) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cc1F)C(=O)N[C@H]1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C25H30FN3O5/c1-2-33-21-10-3-4-11-22(21)34-17-7-6-12-29(15-17)23-19(26)13-16(14-27-23)24(30)28-20-9-5-8-18(20)25(31)32/h3-4,10-11,13-14,17-18,20H,2,5-9,12,15H2,1H3,(H,28,30)(H,31,32)/t17-,18-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323660 ((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((5...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1nc(=O)[nH][nH]1 Show InChI InChI=1S/C21H25N7O4/c1-2-31-16-7-3-4-8-17(16)32-15-6-5-9-28(13-15)20-23-10-14(11-24-20)19(29)22-12-18-25-21(30)27-26-18/h3-4,7-8,10-11,15H,2,5-6,9,12-13H2,1H3,(H,22,29)(H2,25,26,27,30)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323625 (US10188653, Example 14 | US9789110, 14) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(C(O)=O)c1OC |r| Show InChI InChI=1S/C27H30N4O6/c1-3-36-22-11-4-5-12-23(22)37-20-9-7-13-31(17-20)27-29-15-19(16-30-27)25(32)28-14-18-8-6-10-21(26(33)34)24(18)35-2/h4-6,8,10-12,15-16,20H,3,7,9,13-14,17H2,1-2H3,(H,28,32)(H,33,34)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	76.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323621 (US10188653, Example 10 | US9789110, 10) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(ccc1F)C(O)=O |r| Show InChI InChI=1S/C26H27FN4O5/c1-2-35-22-7-3-4-8-23(22)36-20-6-5-11-31(16-20)26-29-14-19(15-30-26)24(32)28-13-18-12-17(25(33)34)9-10-21(18)27/h3-4,7-10,12,14-15,20H,2,5-6,11,13,16H2,1H3,(H,28,32)(H,33,34)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	87.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323592 (US10188653, Example 3 | US9789110, 3) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H](C)c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C27H30N4O5/c1-3-35-23-11-4-5-12-24(23)36-22-10-7-13-31(17-22)27-28-15-21(16-29-27)25(32)30-18(2)19-8-6-9-20(14-19)26(33)34/h4-6,8-9,11-12,14-16,18,22H,3,7,10,13,17H2,1-2H3,(H,30,32)(H,33,34)/t18-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	88.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323589 (US10188653, Example 1 | US9789110, 1) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C26H28N4O5/c1-2-34-22-10-3-4-11-23(22)35-21-9-6-12-30(17-21)26-28-15-20(16-29-26)24(31)27-14-18-7-5-8-19(13-18)25(32)33/h3-5,7-8,10-11,13,15-16,21H,2,6,9,12,14,17H2,1H3,(H,27,31)(H,32,33)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	91.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM347385 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(2- ...) Show SMILES CCOc1ccccc1OC1CCCN(C1)[C@@H](CNC(=O)c1cncnc1)S(C)(=O)=O Show InChI InChI=1S/C21H28N4O5S/c1-3-29-18-8-4-5-9-19(18)30-17-7-6-10-25(14-17)20(31(2,27)28)13-24-21(26)16-11-22-15-23-12-16/h4-5,8-9,11-12,15,17,20H,3,6-7,10,13-14H2,1-2H3,(H,24,26)/t17?,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323658 ((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N,N- d...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N(C)C Show InChI InChI=1S/C20H26N4O3/c1-4-26-17-9-5-6-10-18(17)27-16-8-7-11-24(14-16)20-21-12-15(13-22-20)19(25)23(2)3/h5-6,9-10,12-13,16H,4,7-8,11,14H2,1-3H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323648 (2-((R)-3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((S...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@@H]1CNC(=O)C1 Show InChI InChI=1S/C22H27N5O4/c1-2-30-18-7-3-4-8-19(18)31-17-6-5-9-27(14-17)22-24-11-15(12-25-22)21(29)26-16-10-20(28)23-13-16/h3-4,7-8,11-12,16-17H,2,5-6,9-10,13-14H2,1H3,(H,23,28)(H,26,29)/t16-,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323622 (US10188653, Example 11 | US9789110, 11) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(ccc1OC)C(O)=O |r| Show InChI InChI=1S/C27H30N4O6/c1-3-36-23-8-4-5-9-24(23)37-21-7-6-12-31(17-21)27-29-15-20(16-30-27)25(32)28-14-19-13-18(26(33)34)10-11-22(19)35-2/h4-5,8-11,13,15-16,21H,3,6-7,12,14,17H2,1-2H3,(H,28,32)(H,33,34)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323591 (US10188653, Example 2 | US9789110, 2) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cc(OC)cc(c1)C(O)=O |r| Show InChI InChI=1S/C27H30N4O6/c1-3-36-23-8-4-5-9-24(23)37-21-7-6-10-31(17-21)27-29-15-20(16-30-27)25(32)28-14-18-11-19(26(33)34)13-22(12-18)35-2/h4-5,8-9,11-13,15-16,21H,3,6-7,10,14,17H2,1-2H3,(H,28,32)(H,33,34)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323636 ((R)-N-(2-amino-2- iminoethyl)-2-(3-(2- ethoxypheno...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCC(N)=N Show InChI InChI=1S/C20H26N6O3/c1-2-28-16-7-3-4-8-17(16)29-15-6-5-9-26(13-15)20-24-10-14(11-25-20)19(27)23-12-18(21)22/h3-4,7-8,10-11,15H,2,5-6,9,12-13H2,1H3,(H3,21,22)(H,23,27)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323661 ((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)-N- (2-...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCC(=O)NC Show InChI InChI=1S/C21H27N5O4/c1-3-29-17-8-4-5-9-18(17)30-16-7-6-10-26(14-16)21-24-11-15(12-25-21)20(28)23-13-19(27)22-2/h4-5,8-9,11-12,16H,3,6-7,10,13-14H2,1-2H3,(H,22,27)(H,23,28)/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323656 ((R)-N-(3-amino-3- oxopropyl)-2-(3-(2- ethoxyphenox...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCC(N)=O Show InChI InChI=1S/C21H27N5O4/c1-2-29-17-7-3-4-8-18(17)30-16-6-5-11-26(14-16)21-24-12-15(13-25-21)20(28)23-10-9-19(22)27/h3-4,7-8,12-13,16H,2,5-6,9-11,14H2,1H3,(H2,22,27)(H,23,28)/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323601 (US10188653, Example 7 | US9789110, 7) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ccc(cn1)C(=O)NCc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C27H29N3O5/c1-2-34-23-10-3-4-11-24(23)35-22-9-6-14-30(18-22)25-13-12-21(17-28-25)26(31)29-16-19-7-5-8-20(15-19)27(32)33/h3-5,7-8,10-13,15,17,22H,2,6,9,14,16,18H2,1H3,(H,29,31)(H,32,33)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323630 ((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H30N4O5/c1-2-35-23-10-3-4-11-24(23)36-22-9-6-12-31(18-22)27-29-16-21(17-30-27)26(34)28-15-20-8-5-7-19(13-20)14-25(32)33/h3-5,7-8,10-11,13,16-17,22H,2,6,9,12,14-15,18H2,1H3,(H,28,34)(H,32,33)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323629 ((R)-4-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)pyr...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H28N4O5/c1-2-34-22-7-3-4-8-23(22)35-21-6-5-13-30(17-21)26-28-15-20(16-29-26)24(31)27-14-18-9-11-19(12-10-18)25(32)33/h3-4,7-12,15-16,21H,2,5-6,13-14,17H2,1H3,(H,27,31)(H,32,33)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM323666 ((S)-1-(2-((R)-3-(2- ethoxyphenoxy)piperidin- 1-yl)...) Show SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N1CC[C@H]1C(N)=O Show InChI InChI=1S/C22H27N5O4/c1-2-30-18-7-3-4-8-19(18)31-16-6-5-10-26(14-16)22-24-12-15(13-25-22)21(29)27-11-9-17(27)20(23)28/h3-4,7-8,12-13,16-17H,2,5-6,9-11,14H2,1H3,(H2,23,28)/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...				US Patent US9789110 (2017) BindingDB Entry DOI: 10.7270/Q20G3N81
					More data for this Ligand-Target Pair

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