Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 2077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50069762 (CHEMBL3182437 | ML323 | US9802904, 87) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-n2ccnn2)n1 Show InChI InChI=1S/C23H24N6/c1-16(2)20-6-4-5-7-21(20)23-24-14-17(3)22(27-23)25-15-18-8-10-19(11-9-18)29-13-12-26-28-29/h4-14,16H,15H2,1-3H3,(H,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352028 (US9802904, 89) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NC2(CC2)c2ccc(cc2)-c2cccnc2)n1 Show InChI InChI=1S/C28H28N4/c1-19(2)24-8-4-5-9-25(24)27-30-17-20(3)26(31-27)32-28(14-15-28)23-12-10-21(11-13-23)22-7-6-16-29-18-22/h4-13,16-19H,14-15H2,1-3H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352011 (US9802904, 72) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2ccc(C)nc2)n1 Show InChI InChI=1S/C27H28N4/c1-18(2)24-7-5-6-8-25(24)27-29-15-19(3)26(31-27)30-16-21-10-13-22(14-11-21)23-12-9-20(4)28-17-23/h5-15,17-18H,16H2,1-4H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350387 (US9802904, 60) Show SMILES CCc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C Show InChI InChI=1S/C28H29N3/c1-4-22-19-30-28(26-13-9-8-12-25(26)20(2)3)31-27(22)29-18-21-14-16-24(17-15-21)23-10-6-5-7-11-23/h5-17,19-20H,4,18H2,1-3H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352013 (US9802904, 74) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCC2CCN(CC2)c2cccnc2)n1 Show InChI InChI=1S/C25H31N5/c1-18(2)22-8-4-5-9-23(22)25-27-15-19(3)24(29-25)28-16-20-10-13-30(14-11-20)21-7-6-12-26-17-21/h4-9,12,15,17-18,20H,10-11,13-14,16H2,1-3H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351737 (US9802904, 61) Show SMILES CC(C)c1ccccc1-c1ncc(F)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C26H24FN3/c1-18(2)22-10-6-7-11-23(22)25-29-17-24(27)26(30-25)28-16-19-12-14-21(15-13-19)20-8-4-3-5-9-20/h3-15,17-18H,16H2,1-2H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352018 (US9802904, 79) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2ccc(F)nc2)n1 Show InChI InChI=1S/C26H25FN4/c1-17(2)22-6-4-5-7-23(22)26-29-14-18(3)25(31-26)30-15-19-8-10-20(11-9-19)21-12-13-24(27)28-16-21/h4-14,16-17H,15H2,1-3H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352025 (US9802904, 86) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cccnc2)n1 Show InChI InChI=1S/C26H26N4/c1-18(2)23-8-4-5-9-24(23)26-28-15-19(3)25(30-26)29-16-20-10-12-21(13-11-20)22-7-6-14-27-17-22/h4-15,17-18H,16H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350386 (US9802904, 59) Show SMILES CC(C)c1ccccc1-c1ncc(O)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C26H25N3O/c1-18(2)22-10-6-7-11-23(22)25-28-17-24(30)26(29-25)27-16-19-12-14-21(15-13-19)20-8-4-3-5-9-20/h3-15,17-18,30H,16H2,1-2H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50069762 (CHEMBL3182437 | ML323 | US9802904, 87) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-n2ccnn2)n1 Show InChI InChI=1S/C23H24N6/c1-16(2)20-6-4-5-7-21(20)23-24-14-17(3)22(27-23)25-15-18-8-10-19(11-9-18)29-13-12-26-28-29/h4-14,16H,15H2,1-3H3,(H,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351922 (US9802904, 64) Show SMILES CSc1cnc(nc1NCc1ccc(cc1)-c1ccccc1)-c1ccccc1C(C)C Show InChI InChI=1S/C27H27N3S/c1-19(2)23-11-7-8-12-24(23)26-29-18-25(31-3)27(30-26)28-17-20-13-15-22(16-14-20)21-9-5-4-6-10-21/h4-16,18-19H,17H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352015 (US9802904, 76) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCC2CCN(CC2)c2cnccn2)n1 Show InChI InChI=1S/C24H30N6/c1-17(2)20-6-4-5-7-21(20)24-27-14-18(3)23(29-24)28-15-19-8-12-30(13-9-19)22-16-25-10-11-26-22/h4-7,10-11,14,16-17,19H,8-9,12-13,15H2,1-3H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350385 (US9802904, 59) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C27H27N3/c1-19(2)24-11-7-8-12-25(24)27-28-17-20(3)26(30-27)29-18-21-13-15-23(16-14-21)22-9-5-4-6-10-22/h4-17,19H,18H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350377 (US9802904, 51) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2ccsc2n1 Show InChI InChI=1S/C28H25N3S/c1-19(2)23-10-6-7-11-24(23)27-30-26(25-16-17-32-28(25)31-27)29-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-17,19H,18H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351934 (US9802904, 66) Show SMILES CC(C)c1ccccc1-c1nc(C)c(C)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C28H29N3/c1-19(2)25-12-8-9-13-26(25)28-30-21(4)20(3)27(31-28)29-18-22-14-16-24(17-15-22)23-10-6-5-7-11-23/h5-17,19H,18H2,1-4H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351941 (US9802904, 67) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2cccc(C)c2)n1 Show InChI InChI=1S/C22H25N3/c1-15(2)19-10-5-6-11-20(19)22-23-13-17(4)21(25-22)24-14-18-9-7-8-16(3)12-18/h5-13,15H,14H2,1-4H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350383 (US9802904, 57) Show SMILES CC(C)c1ccccc1C1=NC2C=COC2C(NCc2ccc(cc2)-c2ccccc2)=N1 |c:13,34,t:10| Show InChI InChI=1S/C28H27N3O/c1-19(2)23-10-6-7-11-24(23)27-30-25-16-17-32-26(25)28(31-27)29-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-17,19,25-26H,18H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352027 (US9802904, 88) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cc[nH]n2)n1 Show InChI InChI=1S/C24H25N5/c1-16(2)20-6-4-5-7-21(20)24-25-14-17(3)23(28-24)26-15-18-8-10-19(11-9-18)22-12-13-27-29-22/h4-14,16H,15H2,1-3H3,(H,27,29)(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351827 (US9802904, 63) Show SMILES CC(C)c1ccccc1-c1ncc(N(C)C)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C28H30N4/c1-20(2)24-12-8-9-13-25(24)27-30-19-26(32(3)4)28(31-27)29-18-21-14-16-23(17-15-21)22-10-6-5-7-11-22/h5-17,19-20H,18H2,1-4H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350384 (US9802904, 58) Show SMILES CC(C)c1ccccc1C1=NCCC(NCc2ccc(cc2)-c2ccccc2)=N1 |c:30,t:10| Show InChI InChI=1S/C26H27N3/c1-19(2)23-10-6-7-11-24(23)26-27-17-16-25(29-26)28-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-15,19H,16-18H2,1-2H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352029 (US9802904, 90) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NC(C)(C)c2ccc(cc2)-c2cccnc2)n1 Show InChI InChI=1S/C28H30N4/c1-19(2)24-10-6-7-11-25(24)27-30-17-20(3)26(31-27)32-28(4,5)23-14-12-21(13-15-23)22-9-8-16-29-18-22/h6-19H,1-5H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350381 (US9802904, 55) Show SMILES CC(C)c1ccccc1C1=NC2CNCCC2C(NCc2ccc(cc2)-c2ccccc2)=N1 |c:35,t:10| Show InChI InChI=1S/C29H32N4/c1-20(2)24-10-6-7-11-25(24)29-32-27-19-30-17-16-26(27)28(33-29)31-18-21-12-14-23(15-13-21)22-8-4-3-5-9-22/h3-15,20,26-27,30H,16-19H2,1-2H3,(H,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351968 (US9802904, 69) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2cccs2)n1 Show InChI InChI=1S/C19H21N3S/c1-13(2)16-8-4-5-9-17(16)19-20-11-14(3)18(22-19)21-12-15-7-6-10-23-15/h4-11,13H,12H2,1-3H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350378 (US9802904, 52) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2nc[nH]c2n1 Show InChI InChI=1S/C27H25N5/c1-18(2)22-10-6-7-11-23(22)25-31-26(24-27(32-25)30-17-29-24)28-16-19-12-14-21(15-13-19)20-8-4-3-5-9-20/h3-15,17-18H,16H2,1-2H3,(H2,28,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352021 (US9802904, 82) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cnn[nH]2)n1 Show InChI InChI=1S/C23H24N6/c1-15(2)19-6-4-5-7-20(19)23-24-12-16(3)22(27-23)25-13-17-8-10-18(11-9-17)21-14-26-29-28-21/h4-12,14-15H,13H2,1-3H3,(H,24,25,27)(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351779 (US9802904, 62) Show SMILES CC(C)c1ccccc1-c1ncc(N)c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C26H26N4/c1-18(2)22-10-6-7-11-23(22)25-29-17-24(27)26(30-25)28-16-19-12-14-21(15-13-19)20-8-4-3-5-9-20/h3-15,17-18H,16,27H2,1-2H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350376 (US9802904, 50) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2sccc2n1 Show InChI InChI=1S/C28H25N3S/c1-19(2)23-10-6-7-11-24(23)27-30-25-16-17-32-26(25)28(31-27)29-18-20-12-14-22(15-13-20)21-8-4-3-5-9-21/h3-17,19H,18H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352012 (US9802904, 73) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2ccnc(c2)C(F)(F)F)n1 Show InChI InChI=1S/C27H25F3N4/c1-17(2)22-6-4-5-7-23(22)26-32-15-18(3)25(34-26)33-16-19-8-10-20(11-9-19)21-12-13-31-24(14-21)27(28,29)30/h4-15,17H,16H2,1-3H3,(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350368 (US9802904, 19) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccncc3)cccc2n1 Show InChI InChI=1S/C27H19F3N4/c28-27(29,30)23-5-2-1-4-21(23)26-33-17-22-24(6-3-7-25(22)34-26)32-16-18-8-10-19(11-9-18)20-12-14-31-15-13-20/h1-15,17,32H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351932 (US9802904, 65) Show SMILES CC(C)c1ccccc1-c1nc(C)cc(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C27H27N3/c1-19(2)24-11-7-8-12-25(24)27-29-20(3)17-26(30-27)28-18-21-13-15-23(16-14-21)22-9-5-4-6-10-22/h4-17,19H,18H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352017 (US9802904, 78) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCC2CCN(C2)c2cccnc2)n1 Show InChI InChI=1S/C24H29N5/c1-17(2)21-8-4-5-9-22(21)24-26-13-18(3)23(28-24)27-14-19-10-12-29(16-19)20-7-6-11-25-15-20/h4-9,11,13,15,17,19H,10,12,14,16H2,1-3H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350382 (US9802904, 56) Show SMILES CC(C)c1ccccc1C1=NC2CCCC2C(NCc2ccc(cc2)-c2ccccc2)=N1 |c:34,t:10| Show InChI InChI=1S/C29H31N3/c1-20(2)24-11-6-7-12-25(24)29-31-27-14-8-13-26(27)28(32-29)30-19-21-15-17-23(18-16-21)22-9-4-3-5-10-22/h3-7,9-12,15-18,20,26-27H,8,13-14,19H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350369 (US9802904, 20 | US9802904, 21) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccnc3)cccc2n1 Show InChI InChI=1S/C27H19F3N4/c28-27(29,30)23-7-2-1-6-21(23)26-33-17-22-24(8-3-9-25(22)34-26)32-15-18-10-12-19(13-11-18)20-5-4-14-31-16-20/h1-14,16-17,32H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352008 (US9802904, 70) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NC(CO)c2cccc(C)c2)n1 Show InChI InChI=1S/C23H27N3O/c1-15(2)19-10-5-6-11-20(19)23-24-13-17(4)22(26-23)25-21(14-27)18-9-7-8-16(3)12-18/h5-13,15,21,27H,14H2,1-4H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350365 (US9802904, 16) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccc(Cl)c(Cl)c3)cccc2n1 Show InChI InChI=1S/C28H18Cl2F3N3/c29-23-13-12-19(14-24(23)30)18-10-8-17(9-11-18)15-34-25-6-3-7-26-21(25)16-35-27(36-26)20-4-1-2-5-22(20)28(31,32)33/h1-14,16,34H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350380 (US9802904, 54) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccccc2)c2cccn2n1 Show InChI InChI=1S/C28H26N4/c1-20(2)24-11-6-7-12-25(24)27-30-28(26-13-8-18-32(26)31-27)29-19-21-14-16-23(17-15-21)22-9-4-3-5-10-22/h3-18,20H,19H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350367 (US9802904, 18) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccc(Cl)c3)cccc2n1 Show InChI InChI=1S/C28H19ClF3N3/c29-21-6-3-5-20(15-21)19-13-11-18(12-14-19)16-33-25-9-4-10-26-23(25)17-34-27(35-26)22-7-1-2-8-24(22)28(30,31)32/h1-15,17,33H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350369 (US9802904, 20 | US9802904, 21) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3cccnc3)cccc2n1 Show InChI InChI=1S/C27H19F3N4/c28-27(29,30)23-7-2-1-6-21(23)26-33-17-22-24(8-3-9-25(22)34-26)32-15-18-10-12-19(13-11-18)20-5-4-14-31-16-20/h1-14,16-17,32H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350379 (US9802904, 53) Show SMILES CC(C)c1ccccc1-c1nc2CCCc2c(NCc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C29H29N3/c1-20(2)24-11-6-7-12-25(24)29-31-27-14-8-13-26(27)28(32-29)30-19-21-15-17-23(18-16-21)22-9-4-3-5-10-22/h3-7,9-12,15-18,20H,8,13-14,19H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM351954 (US9802904, 68) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2cccnc2)n1 Show InChI InChI=1S/C20H22N4/c1-14(2)17-8-4-5-9-18(17)20-22-11-15(3)19(24-20)23-13-16-7-6-10-21-12-16/h4-12,14H,13H2,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350366 (US9802904, 17) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccc(Cl)cc3)cccc2n1 Show InChI InChI=1S/C28H19ClF3N3/c29-21-14-12-20(13-15-21)19-10-8-18(9-11-19)16-33-25-6-3-7-26-23(25)17-34-27(35-26)22-4-1-2-5-24(22)28(30,31)32/h1-15,17,33H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350371 (US9802904, 22) Show SMILES FC(F)(F)c1cc(ccc1Cl)-c1ccc(CNc2cccc3nc(ncc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C29H18ClF6N3/c30-24-13-12-19(14-23(24)29(34,35)36)18-10-8-17(9-11-18)15-37-25-6-3-7-26-21(25)16-38-27(39-26)20-4-1-2-5-22(20)28(31,32)33/h1-14,16,37H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM352014 (US9802904, 75) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCC2CCN(CC2)c2ccc(C)nc2)n1 Show InChI InChI=1S/C26H33N5/c1-18(2)23-7-5-6-8-24(23)26-28-15-19(3)25(30-26)29-16-21-11-13-31(14-12-21)22-10-9-20(4)27-17-22/h5-10,15,17-18,21H,11-14,16H2,1-4H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350353 (US9802904, 5) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccccc3)cccc2n1 Show InChI InChI=1S/C22H16F3N3/c23-22(24,25)18-10-5-4-9-16(18)21-27-14-17-19(11-6-12-20(17)28-21)26-13-15-7-2-1-3-8-15/h1-12,14,26H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350357 (US9802904, 9) Show SMILES Fc1ccc(CNc2cccc3nc(ncc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C22H15F4N3/c23-15-10-8-14(9-11-15)12-27-19-6-3-7-20-17(19)13-28-21(29-20)16-4-1-2-5-18(16)22(24,25)26/h1-11,13,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350359 (US9802904, 10) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(Cl)cc3)cccc2n1 Show InChI InChI=1S/C22H15ClF3N3/c23-15-10-8-14(9-11-15)12-27-19-6-3-7-20-17(19)13-28-21(29-20)16-4-1-2-5-18(16)22(24,25)26/h1-11,13,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350354 (US9802904, 6) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)-c3ccccc3)cccc2n1 Show InChI InChI=1S/C28H20F3N3/c29-28(30,31)24-10-5-4-9-22(24)27-33-18-23-25(11-6-12-26(23)34-27)32-17-19-13-15-21(16-14-19)20-7-2-1-3-8-20/h1-16,18,32H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350356 (US9802904, 8) Show SMILES COc1ccc(CNc2cccc3nc(ncc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C23H18F3N3O/c1-30-16-11-9-15(10-12-16)13-27-20-7-4-8-21-18(20)14-28-22(29-21)17-5-2-3-6-19(17)23(24,25)26/h2-12,14,27H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350363 (US9802904, 14) Show SMILES FC(F)(F)c1ccccc1-c1ncc2c(NCc3ccc(cc3)C#N)cccc2n1 Show InChI InChI=1S/C23H15F3N4/c24-23(25,26)19-5-2-1-4-17(19)22-29-14-18-20(6-3-7-21(18)30-22)28-13-16-10-8-15(12-27)9-11-16/h1-11,14,28H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM350374 (US9802904, 24) Show SMILES FC(F)(F)c1cc(ccn1)-c1ccc(CNc2cccc3nc(ncc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C28H18F6N4/c29-27(30,31)22-5-2-1-4-20(22)26-37-16-21-23(6-3-7-24(21)38-26)36-15-17-8-10-18(11-9-17)19-12-13-35-25(14-19)28(32,33)34/h1-14,16,36H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware US Patent					Assay Description This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...				US Patent US9802904 (2017) BindingDB Entry DOI: 10.7270/Q2TF00H8
					More data for this Ligand-Target Pair

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