Compile Data Set for Download or QSAR

Found 329 hits Enz. Inhib. hit(s) with all data for entry = 2604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM276093 (2-(5-bromo-1-(2-chlorobenzyl)-1H-imidazol-4-yl)-4-...) Show SMILES Clc1ccccc1Cn1cnc(c1Br)-c1cc(ccn1)-c1cn[nH]n1 Show InChI InChI=1S/C17H12BrClN6/c18-17-16(14-7-11(5-6-20-14)15-8-22-24-23-15)21-10-25(17)9-12-3-1-2-4-13(12)19/h1-8,10H,9H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319638 (2-{1-[2-(2-chlorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2Cl)cn1 Show InChI InChI=1S/C19H14ClF3N6/c20-14-4-2-1-3-12(14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319638 (2-{1-[2-(2-chlorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2Cl)cn1 Show InChI InChI=1S/C19H14ClF3N6/c20-14-4-2-1-3-12(14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319639 (2-{1-[(1,2,3,4-tetrahydronaphthalen-1-yl)methyl]- ...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319639 (2-{1-[(1,2,3,4-tetrahydronaphthalen-1-yl)methyl]- ...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319640 (2-{1-[2-(2-ethoxyphenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C21H19F3N6O/c1-2-31-18-6-4-3-5-14(18)8-10-30-12-17(26-13-30)16-11-15(7-9-25-16)19-20(21(22,23)24)28-29-27-19/h3-7,9,11-13H,2,8,10H2,1H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319642 (2-{1-[(4-fluorophenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Fc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C18H12F4N6/c19-13-3-1-11(2-4-13)8-28-9-15(24-10-28)14-7-12(5-6-23-14)16-17(18(20,21)22)26-27-25-16/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319643 (2-{1-[(4-fluorophenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Fc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C18H12F4N6/c19-13-4-2-1-3-12(13)8-28-9-15(24-10-28)14-7-11(5-6-23-14)16-17(18(20,21)22)26-27-25-16/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319644 (2-{1-[(4-chlorophenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2ccc(Cl)cc2)cn1 Show InChI InChI=1S/C18H12ClF3N6/c19-13-3-1-11(2-4-13)8-28-9-15(24-10-28)14-7-12(5-6-23-14)16-17(18(20,21)22)26-27-25-16/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319645 (2-{1-[(2-chlorophenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2ccccc2Cl)cn1 Show InChI InChI=1S/C18H12ClF3N6/c19-13-4-2-1-3-12(13)8-28-9-15(24-10-28)14-7-11(5-6-23-14)16-17(18(20,21)22)26-27-25-16/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319646 (2-{1-[(4-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6/c1-12-2-4-13(5-3-12)9-28-10-16(24-11-28)15-8-14(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319647 (2-{1-[(2-methylphenyl)methyl]-1H-imidazol-4-yl}-4-...) Show SMILES Cc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C19H15F3N6/c1-12-4-2-3-5-14(12)9-28-10-16(24-11-28)15-8-13(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319648 (2-{1-[(4-methoxyphenyl)methyl]-1H-imidazol-4-yl}- ...) Show SMILES COc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H15F3N6O/c1-29-14-4-2-12(3-5-14)9-28-10-16(24-11-28)15-8-13(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319649 (2-{1-[(2,4-difluorophenyl)methyl]-1H-imidazol-4- y...) Show SMILES Fc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1 Show InChI InChI=1S/C18H11F5N6/c19-12-2-1-11(13(20)6-12)7-29-8-15(25-9-29)14-5-10(3-4-24-14)16-17(18(21,22)23)27-28-26-16/h1-6,8-9H,7H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319650 (2-{1-[(2,6-difluorophenyl)methyl]-1H-imidazol-4- y...) Show SMILES Fc1cccc(F)c1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C18H11F5N6/c19-12-2-1-3-13(20)11(12)7-29-8-15(25-9-29)14-6-10(4-5-24-14)16-17(18(21,22)23)27-28-26-16/h1-6,8-9H,7H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319651 (2-{1-[(4-fluoro-2-methylphenyl)methyl]-1H- imidazo...) Show SMILES Cc1cc(F)ccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C19H14F4N6/c1-11-6-14(20)3-2-13(11)8-29-9-16(25-10-29)15-7-12(4-5-24-15)17-18(19(21,22)23)27-28-26-17/h2-7,9-10H,8H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319652 (2-{1-[(2-fluoro-4-methylphenyl)methyl]-1H- imidazo...) Show SMILES Cc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1 Show InChI InChI=1S/C19H14F4N6/c1-11-2-3-13(14(20)6-11)8-29-9-16(25-10-29)15-7-12(4-5-24-15)17-18(19(21,22)23)27-28-26-17/h2-7,9-10H,8H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319653 (2-(1-benzyl-1H-imidazol-4-yl)-4-[5- (trifluorometh...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2ccccc2)cn1 Show InChI InChI=1S/C18H13F3N6/c19-18(20,21)17-16(24-26-25-17)13-6-7-22-14(8-13)15-10-27(11-23-15)9-12-4-2-1-3-5-12/h1-8,10-11H,9H2,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319654 (2-[1-(1-phenylethyl)-1H-imidazol-4-yl]-4-[5- (trif...) Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319655 (2-[1-(1-phenylpropyl)-1H-imidazol-4-yl]-4-[5- (tri...) Show SMILES CCC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM373163 (2-{1-[2-(4-fluorophenyl)ethyl]-1H-imidazol- 4-yl}-...) Show SMILES Fc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H14F4N6/c20-14-3-1-12(2-4-14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM373163 (2-{1-[2-(4-fluorophenyl)ethyl]-1H-imidazol- 4-yl}-...) Show SMILES Fc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C19H14F4N6/c20-14-3-1-12(2-4-14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319659 (2-{1-[2-(3-fluorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES Fc1cccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1 Show InChI InChI=1S/C19H14F4N6/c20-14-3-1-2-12(8-14)5-7-29-10-16(25-11-29)15-9-13(4-6-24-15)17-18(19(21,22)23)27-28-26-17/h1-4,6,8-11H,5,7H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319659 (2-{1-[2-(3-fluorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES Fc1cccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1 Show InChI InChI=1S/C19H14F4N6/c20-14-3-1-2-12(8-14)5-7-29-10-16(25-11-29)15-9-13(4-6-24-15)17-18(19(21,22)23)27-28-26-17/h1-4,6,8-11H,5,7H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319660 (2-{1-[2-(2,3-difluorophenyl)ethyl]-1H-imidazol- 4-...) Show SMILES Fc1cccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1F Show InChI InChI=1S/C19H13F5N6/c20-13-3-1-2-11(16(13)21)5-7-30-9-15(26-10-30)14-8-12(4-6-25-14)17-18(19(22,23)24)28-29-27-17/h1-4,6,8-10H,5,7H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319660 (2-{1-[2-(2,3-difluorophenyl)ethyl]-1H-imidazol- 4-...) Show SMILES Fc1cccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1F Show InChI InChI=1S/C19H13F5N6/c20-13-3-1-2-11(16(13)21)5-7-30-9-15(26-10-30)14-8-12(4-6-25-14)17-18(19(22,23)24)28-29-27-17/h1-4,6,8-10H,5,7H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319662 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2-{1...) Show SMILES Fc1cc(F)c(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1F Show InChI InChI=1S/C19H12F6N6/c20-12-7-14(22)13(21)5-10(12)2-4-31-8-16(27-9-31)15-6-11(1-3-26-15)17-18(19(23,24)25)29-30-28-17/h1,3,5-9H,2,4H2,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319662 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2-{1...) Show SMILES Fc1cc(F)c(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1F Show InChI InChI=1S/C19H12F6N6/c20-12-7-14(22)13(21)5-10(12)2-4-31-8-16(27-9-31)15-6-11(1-3-26-15)17-18(19(23,24)25)29-30-28-17/h1,3,5-9H,2,4H2,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319663 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- {...) Show SMILES Fc1cc(F)c(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1 Show InChI InChI=1S/C19H12F6N6/c20-11-6-13(21)12(14(22)7-11)2-4-31-8-16(27-9-31)15-5-10(1-3-26-15)17-18(19(23,24)25)29-30-28-17/h1,3,5-9H,2,4H2,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319664 (2-{1-[(2,3-dihydro-1H-inden-1-yl)methyl]-1H- imida...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCc3ccccc23)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319665 (2-{1-[2-(2-fluorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES Fc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C19H14F4N6/c20-14-4-2-1-3-12(14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319665 (2-{1-[2-(2-fluorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES Fc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C19H14F4N6/c20-14-4-2-1-3-12(14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319666 (2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imid...) Show SMILES Fc1ccc2CCC(c2c1)n1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319666 (2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imid...) Show SMILES Fc1ccc2CCC(c2c1)n1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319667 (2-{1-[2-(2,4-difluorophenyl)ethyl]-1H-imidazol-4- ...) Show SMILES Fc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1 Show InChI InChI=1S/C19H13F5N6/c20-13-2-1-11(14(21)8-13)4-6-30-9-16(26-10-30)15-7-12(3-5-25-15)17-18(19(22,23)24)28-29-27-17/h1-3,5,7-10H,4,6H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319667 (2-{1-[2-(2,4-difluorophenyl)ethyl]-1H-imidazol-4- ...) Show SMILES Fc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1 Show InChI InChI=1S/C19H13F5N6/c20-13-2-1-11(14(21)8-13)4-6-30-9-16(26-10-30)15-7-12(3-5-25-15)17-18(19(22,23)24)28-29-27-17/h1-3,5,7-10H,4,6H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319668 (2-{1-[2-(2,6-difluorophenyl)ethyl]-1H-imidazol-4- ...) Show SMILES Fc1cccc(F)c1CCn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C19H13F5N6/c20-13-2-1-3-14(21)12(13)5-7-30-9-16(26-10-30)15-8-11(4-6-25-15)17-18(19(22,23)24)28-29-27-17/h1-4,6,8-10H,5,7H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319669 (2-{1-[2-(2,5-difluorophenyl)ethyl]-1H-imidazol-4- ...) Show SMILES Fc1ccc(F)c(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1 Show InChI InChI=1S/C19H13F5N6/c20-13-1-2-14(21)11(7-13)4-6-30-9-16(26-10-30)15-8-12(3-5-25-15)17-18(19(22,23)24)28-29-27-17/h1-3,5,7-10H,4,6H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319669 (2-{1-[2-(2,5-difluorophenyl)ethyl]-1H-imidazol-4- ...) Show SMILES Fc1ccc(F)c(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c1 Show InChI InChI=1S/C19H13F5N6/c20-13-1-2-14(21)11(7-13)4-6-30-9-16(26-10-30)15-8-12(3-5-25-15)17-18(19(22,23)24)28-29-27-17/h1-3,5,7-10H,4,6H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319670 (2-{1-[(3R)-1-benzoylpiperidin-3-yl]-1H-imidazol-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(cn1)[C@@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319670 (2-{1-[(3R)-1-benzoylpiperidin-3-yl]-1H-imidazol-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(cn1)[C@@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319671 (2-{1-[(3S)-1-benzoylpiperidin-3-yl]-1H-imidazol-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(cn1)[C@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319671 (2-{1-[(3S)-1-benzoylpiperidin-3-yl]-1H-imidazol-4-...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(cn1)[C@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319672 (2-{1-[2-(4-methylphenyl)ethyl]-1H-imidazol-4-yl}- ...) Show SMILES Cc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6/c1-13-2-4-14(5-3-13)7-9-29-11-17(25-12-29)16-10-15(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319673 (2-{1-[2-(4-chlorophenyl)ethyl]-1H-imidazol-4-yl}-4...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccc(Cl)cc2)cn1 Show InChI InChI=1S/C19H14ClF3N6/c20-14-3-1-12(2-4-14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319674 (2-{1-[2-(4-methoxyphenyl)ethyl]-1H-imidazol-4-yl}-...) Show SMILES COc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6O/c1-30-15-4-2-13(3-5-15)7-9-29-11-17(25-12-29)16-10-14(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319674 (2-{1-[2-(4-methoxyphenyl)ethyl]-1H-imidazol-4-yl}-...) Show SMILES COc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1 Show InChI InChI=1S/C20H17F3N6O/c1-30-15-4-2-13(3-5-15)7-9-29-11-17(25-12-29)16-10-14(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319678 (2-[5-(4-fluorophenyl)-1-methyl-1H-imidazol-4-yl]-4...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C18H12F4N6/c1-28-9-24-15(16(28)10-2-4-12(19)5-3-10)13-8-11(6-7-23-13)14-17(18(20,21)22)26-27-25-14/h2-9H,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319678 (2-[5-(4-fluorophenyl)-1-methyl-1H-imidazol-4-yl]-4...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1nn[nH]c1C(F)(F)F Show InChI InChI=1S/C18H12F4N6/c1-28-9-24-15(16(28)10-2-4-12(19)5-3-10)13-8-11(6-7-23-13)14-17(18(20,21)22)26-27-25-14/h2-9H,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair

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