Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4917 ((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4915 (3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4917 ((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4907 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4882 ((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4915 (3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4882 ((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4922 (3-(2-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4906 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4919 (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4919 (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4922 (3-(2-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4917 ((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4921 (3-(2-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4920 (3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4905 ((3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4906 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4921 (3-(2-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4914 (3-(2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4920 (3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4919 (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4907 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4916 (3-(2-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4917 ((3Z)-3-{[3-(2-carboxyethyl)-4,5,6,7-tetrahydro-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4906 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4914 (3-(2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4915 (3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4914 (3-(2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4907 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4904 ((3Z)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethyliden...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4882 ((Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4916 (3-(2-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4920 (3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4916 (3-(2-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4810 ((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4916 (3-(2-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <780 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4921 (3-(2-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4921 (3-(2-{[(3Z)-6-(2-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4922 (3-(2-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4905 ((3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4907 ((3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4919 (3-(2-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H-indol-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4915 (3-(2-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM4920 (3-(2-{[(3Z)-6-(3-methoxyphenyl)-2-oxo-2,3-dihydro-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4918 (3-(2-{[(3Z)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4914 (3-(2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4908 ((3Z)-6-methoxy-3-(4,5,6,7-tetrahydro-1H-indol-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM4904 ((3Z)-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethyliden...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | J Med Chem 43: 2655-63 (2000) Article DOI: 10.1021/jm9906116 BindingDB Entry DOI: 10.7270/Q2W66J0N | |||||||||||
More data for this Ligand-Target Pair |
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