Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310191 (4-(4-chlorophenyl)-1-(3-(3,4-dihydroisoquinolin-2(...) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClN3O2/c23-19-5-7-20(8-6-19)25-11-12-26(22(28)16-25)15-21(27)14-24-10-9-17-3-1-2-4-18(17)13-24/h1-8,21,27H,9-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310196 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc(c1)N1CCOCC1 Show InChI InChI=1S/C26H34N4O3/c31-25(18-27-9-8-21-4-1-2-5-22(21)17-27)19-30-11-10-29(20-26(30)32)24-7-3-6-23(16-24)28-12-14-33-15-13-28/h1-7,16,25,31H,8-15,17-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310192 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cncc(c1)N1CCOCC1 Show InChI InChI=1S/C25H33N5O3/c31-24(17-27-6-5-20-3-1-2-4-21(20)16-27)18-30-8-7-29(19-25(30)32)23-13-22(14-26-15-23)28-9-11-33-12-10-28/h1-4,13-15,24,31H,5-12,16-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310188 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc2cccnc12 Show InChI InChI=1S/C25H28N4O2/c30-22(16-27-12-10-19-5-1-2-6-21(19)15-27)17-29-14-13-28(18-24(29)31)23-9-3-7-20-8-4-11-26-25(20)23/h1-9,11,22,30H,10,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310189 (4-(3-chlorophenyl)-1-(3-(3,4-dihydroisoquinolin-2(...) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc(Cl)c1 Show InChI InChI=1S/C22H26ClN3O2/c23-19-6-3-7-20(12-19)25-10-11-26(22(28)16-25)15-21(27)14-24-9-8-17-4-1-2-5-18(17)13-24/h1-7,12,21,27H,8-11,13-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310190 (US10150758, Compound 6) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1cccc(F)c1 Show InChI InChI=1S/C22H26FN3O2/c23-19-6-3-7-20(12-19)25-10-11-26(22(28)16-25)15-21(27)14-24-9-8-17-4-1-2-5-18(17)13-24/h1-7,12,21,27H,8-11,13-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310185 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES OC(CN1C(=O)Cc2ccccc12)CN1CCc2ccccc2C1 Show InChI InChI=1S/C20H22N2O2/c23-18(13-21-10-9-15-5-1-2-7-17(15)12-21)14-22-19-8-4-3-6-16(19)11-20(22)24/h1-8,18,23H,9-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310202 (BDBM310203 | US10150758, Compound 18) Show SMILES O[C@H](CN1CCc2ccccc2C1)Cn1ccc(Nc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H25N3O2/c27-22(16-25-12-10-18-6-4-5-7-19(18)15-25)17-26-13-11-21(14-23(26)28)24-20-8-2-1-3-9-20/h1-9,11,13-14,22,24,27H,10,12,15-17H2/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310217 (US10150758, Compound 33) Show SMILES OC(CN1CCc2ccccc2C1)Cn1ccc(cc1=O)C(=O)NC1CCOCC1 Show InChI InChI=1S/C23H29N3O4/c27-21(15-25-9-5-17-3-1-2-4-19(17)14-25)16-26-10-6-18(13-22(26)28)23(29)24-20-7-11-30-12-8-20/h1-4,6,10,13,20-21,27H,5,7-9,11-12,14-16H2,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310215 (4-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES OC(CN1CCc2ccccc2C1)CN1C(=O)COc2ccccc12 Show InChI InChI=1S/C20H22N2O3/c23-17(12-21-10-9-15-5-1-2-6-16(15)11-21)13-22-18-7-3-4-8-19(18)25-14-20(22)24/h1-8,17,23H,9-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310213 (US10150758, Compound 29) Show SMILES CN(C)c1ccccc1N1CCN(C[C@H](O)CN2CCc3ccccc3C2)C(=O)C1 |r| Show InChI InChI=1S/C24H32N4O2/c1-25(2)22-9-5-6-10-23(22)27-13-14-28(24(30)18-27)17-21(29)16-26-12-11-19-7-3-4-8-20(19)15-26/h3-10,21,29H,11-18H2,1-2H3/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310204 (US10150758, Compound 20) Show SMILES OCc1ccc(cc1)N1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C23H29N3O3/c27-17-18-5-7-21(8-6-18)25-11-12-26(23(29)16-25)15-22(28)14-24-10-9-19-3-1-2-4-20(19)13-24/h1-8,22,27-28H,9-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310199 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES Cc1ccc(cc1)N1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C23H29N3O2/c1-18-6-8-21(9-7-18)25-12-13-26(23(28)17-25)16-22(27)15-24-11-10-19-4-2-3-5-20(19)14-24/h2-9,22,27H,10-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310193 (US10150758, Compound 9) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1ccccc1Cl Show InChI InChI=1S/C22H26ClN3O2/c23-20-7-3-4-8-21(20)25-11-12-26(22(28)16-25)15-19(27)14-24-10-9-17-5-1-2-6-18(17)13-24/h1-8,19,27H,9-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310218 (US10150758, Compound 34) Show SMILES OC(CN1CCc2ccccc2C1)Cn1cnc(cc1=O)C(=O)NC1CCOCC1 Show InChI InChI=1S/C22H28N4O4/c27-19(13-25-8-5-16-3-1-2-4-17(16)12-25)14-26-15-23-20(11-21(26)28)22(29)24-18-6-9-30-10-7-18/h1-4,11,15,18-19,27H,5-10,12-14H2,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310214 (US10150758, Compound 30) Show SMILES CN(C)c1ccc(cc1)N1CCN(C[C@H](O)CN2CCc3ccccc3C2)C(=O)C1 |r| Show InChI InChI=1S/C24H32N4O2/c1-25(2)21-7-9-22(10-8-21)27-13-14-28(24(30)18-27)17-23(29)16-26-12-11-19-5-3-4-6-20(19)15-26/h3-10,23,29H,11-18H2,1-2H3/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310212 (US10150758, Compound 28) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCOCC1=O Show InChI InChI=1S/C16H22N2O3/c19-15(11-18-7-8-21-12-16(18)20)10-17-6-5-13-3-1-2-4-14(13)9-17/h1-4,15,19H,5-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310200 (US10150758, Compound 16) Show SMILES O[C@H](CN1CCc2ccccc2C1)CN1CCC(CC1=O)c1ccccc1 |r| Show InChI InChI=1S/C23H28N2O2/c26-22(16-24-12-10-19-8-4-5-9-21(19)15-24)17-25-13-11-20(14-23(25)27)18-6-2-1-3-7-18/h1-9,20,22,26H,10-17H2/t20?,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310201 (US10150758, Compound 17) Show SMILES O[C@@H](CN1CCc2ccccc2C1)CN1CCC(CC1=O)c1ccccc1 |r| Show InChI InChI=1S/C23H28N2O2/c26-22(16-24-12-10-19-8-4-5-9-21(19)15-24)17-25-13-11-20(14-23(25)27)18-6-2-1-3-7-18/h1-9,20,22,26H,10-17H2/t20?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310205 (US10150758, Compound 21) Show SMILES CC(=O)N1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C18H25N3O3/c1-14(22)20-8-9-21(18(24)13-20)12-17(23)11-19-7-6-15-4-2-3-5-16(15)10-19/h2-5,17,23H,6-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310206 (US10150758, Compound 22) Show SMILES CS(=O)(=O)N1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C17H25N3O4S/c1-25(23,24)20-9-8-19(17(22)13-20)12-16(21)11-18-7-6-14-4-2-3-5-15(14)10-18/h2-5,16,21H,6-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310207 (US10150758, Compound 23) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)C1CCOCC1 Show InChI InChI=1S/C21H31N3O3/c25-20(14-22-8-5-17-3-1-2-4-18(17)13-22)15-24-10-9-23(16-21(24)26)19-6-11-27-12-7-19/h1-4,19-20,25H,5-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310208 (US10150758, Compound 24) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(Cc2ccccc2)CC1=O Show InChI InChI=1S/C23H29N3O2/c27-22(16-24-11-10-20-8-4-5-9-21(20)15-24)17-26-13-12-25(18-23(26)28)14-19-6-2-1-3-7-19/h1-9,22,27H,10-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310209 (US10150758, Compound 25) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(Cc2ccccn2)CC1=O Show InChI InChI=1S/C22H28N4O2/c27-21(15-24-10-8-18-5-1-2-6-19(18)13-24)16-26-12-11-25(17-22(26)28)14-20-7-3-4-9-23-20/h1-7,9,21,27H,8,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310210 (US10150758, Compound 26) Show SMILES OC(CN1CCc2ccccc2C1)CN1CCN(Cc2cccnc2)CC1=O Show InChI InChI=1S/C22H28N4O2/c27-21(15-24-9-7-19-5-1-2-6-20(19)14-24)16-26-11-10-25(17-22(26)28)13-18-4-3-8-23-12-18/h1-6,8,12,21,27H,7,9-11,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310202 (BDBM310203 | US10150758, Compound 18) Show SMILES O[C@H](CN1CCc2ccccc2C1)Cn1ccc(Nc2ccccc2)cc1=O |r| Show InChI InChI=1S/C23H25N3O2/c27-22(16-25-12-10-18-6-4-5-7-19(18)15-25)17-26-13-11-21(14-23(26)28)24-20-8-2-1-3-9-20/h1-9,11,13-14,22,24,27H,10,12,15-17H2/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310216 (US10150758, Compound 32) Show SMILES OC(CN1CC(CC1=O)C(=O)NC1CCOCC1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C22H31N3O4/c26-20(14-24-8-5-16-3-1-2-4-17(16)12-24)15-25-13-18(11-21(25)27)22(28)23-19-6-9-29-10-7-19/h1-4,18-20,26H,5-15H2,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310186 (US10150758, Compound 2) Show SMILES OC(CN1CCc2ccccc2C1)Cc1cccc(=O)[nH]1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310187 (1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...) Show SMILES Cc1cccc(c1)N1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C23H29N3O2/c1-18-5-4-8-21(13-18)25-11-12-26(23(28)17-25)16-22(27)15-24-10-9-19-6-2-3-7-20(19)14-24/h2-8,13,22,27H,9-12,14-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM310211 (US10150758, Compound 27) Show SMILES CN1CCN(CC(O)CN2CCc3ccccc3C2)C(=O)C1 Show InChI InChI=1S/C17H25N3O2/c1-18-8-9-20(17(22)13-18)12-16(21)11-19-7-6-14-4-2-3-5-15(14)10-19/h2-5,16,21H,6-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10150758 (2018) BindingDB Entry DOI: 10.7270/Q2W95C8T
					More data for this Ligand-Target Pair