Compile Data Set for Download or QSAR

Found 41 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205030 (US9556132, 7 | process for preparing 2-(2-{2-[1-(2...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1OCC#N Show InChI InChI=1S/C21H14FN5O/c22-18-10-4-5-11-19(18)27-21(24-25-26-27)17-9-2-1-7-15(17)16-8-3-6-12-20(16)28-14-13-23/h1-12H,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205069 (US9556132, 33 | process for preparing 5-{2-[2-(flu...) Show SMILES FCc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H14F2N4/c21-13-14-7-1-2-8-15(14)16-9-3-4-10-17(16)20-23-24-25-26(20)19-12-6-5-11-18(19)22/h1-12H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205019 (US9556132, 4 | process for preparing 1-(2-fluoroph...) Show SMILES COCCOc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C22H19FN4O2/c1-28-14-15-29-21-13-7-4-9-17(21)16-8-2-3-10-18(16)22-24-25-26-27(22)20-12-6-5-11-19(20)23/h2-13H,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205016 (US9556132, 3 | process for preparing 5-[2-(2-ethox...) Show SMILES CCOc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H17FN4O/c1-2-27-20-14-8-5-10-16(20)15-9-3-4-11-17(15)21-23-24-25-26(21)19-13-7-6-12-18(19)22/h3-14H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205066 (US9556132, 30 | process for preparing (e)-n-[(2-{2...) Show SMILES O\N=C/c1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H14FN5O/c21-18-11-5-6-12-19(18)26-20(23-24-25-26)17-10-4-3-9-16(17)15-8-2-1-7-14(15)13-22-27/h1-13,27H/b22-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205065 (US9556132, 29 | process for preparing 1-(2-fluorop...) Show SMILES COCc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H17FN4O/c1-27-14-15-8-2-3-9-16(15)17-10-4-5-11-18(17)21-23-24-25-26(21)20-13-7-6-12-19(20)22/h2-13H,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205077 (US9556132, 56 | process for preparing 2-{5-[2-(2-m...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1C#N Show InChI InChI=1S/C21H15N5O/c1-27-20-13-7-5-10-17(20)16-9-3-4-11-18(16)21-23-24-25-26(21)19-12-6-2-8-15(19)14-22/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205079 (US9556132, 59 | process for preparing 1-[2-(difluo...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1OC(F)F Show InChI InChI=1S/C21H16F2N4O2/c1-28-18-12-6-4-9-15(18)14-8-2-3-10-16(14)20-24-25-26-27(20)17-11-5-7-13-19(17)29-21(22)23/h2-13,21H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	69	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205050 (US9556132, 13 | process for preparing 1-(2-fluorop...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H15FN4O/c1-26-19-13-7-4-9-15(19)14-8-2-3-10-16(14)20-22-23-24-25(20)18-12-6-5-11-17(18)21/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205067 (US9556132, 31 | process for preparing 2-{2-[1-(2-f...) Show SMILES O\N=C\c1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H14FN5O/c21-18-11-5-6-12-19(18)26-20(23-24-25-26)17-10-4-3-9-16(17)15-8-2-1-7-14(15)13-22-27/h1-13,27H/b22-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205053 (US9556132, 16 | process for preparing 1-(2-fluorop...) Show SMILES COCOc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H17FN4O2/c1-27-14-28-20-13-7-4-9-16(20)15-8-2-3-10-17(15)21-23-24-25-26(21)19-12-6-5-11-18(19)22/h2-13H,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205080 (US9556132, 62 | process for preparing 2-(5-{2-[2-(...) Show SMILES FC(F)Oc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1C#N Show InChI InChI=1S/C21H13F2N5O/c22-21(23)29-19-12-6-4-9-16(19)15-8-2-3-10-17(15)20-25-26-27-28(20)18-11-5-1-7-14(18)13-24/h1-12,21H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205022 (US9556132, 40 | US9556132, 5) Show SMILES FC(F)Oc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H13F3N4O/c21-16-10-4-5-11-17(16)27-19(24-25-26-27)15-9-2-1-7-13(15)14-8-3-6-12-18(14)28-20(22)23/h1-12,20H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205056 (US9556132, 20 | process for preparing 5-[2-(2-ethy...) Show SMILES CCc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H17FN4/c1-2-15-9-3-4-10-16(15)17-11-5-6-12-18(17)21-23-24-25-26(21)20-14-8-7-13-19(20)22/h3-14H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205049 (US9556132, 12 | process for preparing 5-{2-[2-(flu...) Show SMILES FCOc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H14F2N4O/c21-13-27-19-12-6-3-8-15(19)14-7-1-2-9-16(14)20-23-24-25-26(20)18-11-5-4-10-17(18)22/h1-12H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205060 (US9556132, 24 | US9556132, 25 | process for prepar...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1Cl Show InChI InChI=1S/C19H12ClFN4/c20-16-10-4-3-8-14(16)13-7-1-2-9-15(13)19-22-23-24-25(19)18-12-6-5-11-17(18)21/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205051 (US9556132, 14 | process for preparing 1-(2-fluorop...) Show SMILES CSc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H15FN4S/c1-26-19-13-7-4-9-15(19)14-8-2-3-10-16(14)20-22-23-24-25(20)18-12-6-5-11-17(18)21/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	460	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205055 (US9556132, 19 | process for preparing 1-(2-fluorop...) Show SMILES Cc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H15FN4/c1-14-8-2-3-9-15(14)16-10-4-5-11-17(16)20-22-23-24-25(20)19-13-7-6-12-18(19)21/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205073 (US9556132, 49 | process for preparing 1-(2-chlorop...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1Cl Show InChI InChI=1S/C20H15ClN4O/c1-26-19-13-7-4-9-15(19)14-8-2-3-10-16(14)20-22-23-24-25(20)18-12-6-5-11-17(18)21/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205057 (US9556132, 21 | process for preparing 2-{2-[1-(2-f...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1C=O Show InChI InChI=1S/C20H13FN4O/c21-18-11-5-6-12-19(18)25-20(22-23-24-25)17-10-4-3-9-16(17)15-8-2-1-7-14(15)13-26/h1-13H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205059 (US9556132, 23 | process for preparing 5-[2-(2-brom...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1Br Show InChI InChI=1S/C19H12BrFN4/c20-16-10-4-3-8-14(16)13-7-1-2-9-15(13)19-22-23-24-25(19)18-12-6-5-11-17(18)21/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205044 (US9556132, 8 | process for preparing methyl 2-(2-{...) Show SMILES COC(=O)COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C22H17FN4O3/c1-29-21(28)14-30-20-13-7-4-9-16(20)15-8-2-3-10-17(15)22-24-25-26-27(22)19-12-6-5-11-18(19)23/h2-13H,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205071 (US9556132, 42 | process for preparing 2-{2-[1-(2-f...) Show SMILES COCCNc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C22H20FN5O/c1-29-15-14-24-20-12-6-4-9-17(20)16-8-2-3-10-18(16)22-25-26-27-28(22)21-13-7-5-11-19(21)23/h2-13,24H,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205060 (US9556132, 24 | US9556132, 25 | process for prepar...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1Cl Show InChI InChI=1S/C19H12ClFN4/c20-16-10-4-3-8-14(16)13-7-1-2-9-15(13)19-22-23-24-25(19)18-12-6-5-11-17(18)21/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205028 (US9556132, 6 | process for preparing 5-{2-[2-(cycl...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1OCC1CC1 Show InChI InChI=1S/C23H19FN4O/c24-20-10-4-5-11-21(20)28-23(25-26-27-28)19-9-2-1-7-17(19)18-8-3-6-12-22(18)29-15-16-13-14-16/h1-12,16H,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	710	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205064 (US9556132, 28 | process for preparing (2-{2-[1-(2-...) Show SMILES OCc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H15FN4O/c21-18-11-5-6-12-19(18)25-20(22-23-24-25)17-10-4-3-9-16(17)15-8-2-1-7-14(15)13-26/h1-12,26H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205045 (US9556132, 9 | process for preparing 1-(2-fluoroph...) Show SMILES CC(C)Oc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C22H19FN4O/c1-15(2)28-21-14-8-5-10-17(21)16-9-3-4-11-18(16)22-24-25-26-27(22)20-13-7-6-12-19(20)23/h3-15H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205076 (US9556132, 54 | process for preparing 5-[2-(2-fluo...) Show SMILES COc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1F Show InChI InChI=1S/C20H15FN4O/c1-26-19-13-7-6-12-18(19)25-20(22-23-24-25)16-10-3-2-8-14(16)15-9-4-5-11-17(15)21/h2-13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	780	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205022 (US9556132, 40 | US9556132, 5) Show SMILES FC(F)Oc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H13F3N4O/c21-16-10-4-5-11-17(16)27-19(24-25-26-27)15-9-2-1-7-13(15)14-8-3-6-12-18(14)28-20(22)23/h1-12,20H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205062 (US9556132, 26 | process for preparing 2-{2-[1-(2-f...) Show SMILES CN(C)c1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H18FN5/c1-26(2)19-13-7-5-10-16(19)15-9-3-4-11-17(15)21-23-24-25-27(21)20-14-8-6-12-18(20)22/h3-14H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	820	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205068 (US9556132, 32 | process for preparing 5-{2-[2-(dif...) Show SMILES FC(F)c1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C20H13F3N4/c21-17-11-5-6-12-18(17)27-20(24-25-26-27)16-10-4-2-8-14(16)13-7-1-3-9-15(13)19(22)23/h1-12,19H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	870	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205081 (US9556132, 65 | process for preparing 1-phenyl-5-(...) Show SMILES c1ccc(cc1)\N=C(/c1ccccc1-c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C25H18N4/c1-3-11-19(12-4-1)21-15-7-8-16-22(21)25(26-20-13-5-2-6-14-20)29-24-18-10-9-17-23(24)27-28-29/h1-18H/b26-25+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	890	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205063 (US9556132, 27 | process for preparing 2-{2-[1-(2-f...) Show SMILES Nc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C19H14FN5/c20-16-10-4-6-12-18(16)25-19(22-23-24-25)15-9-2-1-7-13(15)14-8-3-5-11-17(14)21/h1-12H,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205054 (US9556132, 17 | process for preparing 2-(2-{2-[1-(...) Show SMILES NC(=O)COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1F Show InChI InChI=1S/C21H16FN5O2/c22-17-10-4-5-11-18(17)27-21(24-25-26-27)16-9-2-1-7-14(16)15-8-3-6-12-19(15)29-13-20(23)28/h1-12H,13H2,(H2,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205072 (US9556132, 48 | process for preparing 1-(2-chlorop...) Show SMILES Fc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1Cl Show InChI InChI=1S/C19H12ClFN4/c20-16-10-4-6-12-18(16)25-19(22-23-24-25)15-9-2-1-7-13(15)14-8-3-5-11-17(14)21/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205078 (US9556132, 58 | process for preparing 1-[2-(difluo...) Show SMILES FC(F)Oc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1F Show InChI InChI=1S/C20H13F3N4O/c21-16-10-4-3-8-14(16)13-7-1-2-9-15(13)19-24-25-26-27(19)17-11-5-6-12-18(17)28-20(22)23/h1-12,20H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205075 (US9556132, 53 | process for preparing 2-{5-[2-(2-m...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1O Show InChI InChI=1S/C20H16N4O2/c1-26-19-13-7-4-9-15(19)14-8-2-3-10-16(14)20-21-22-23-24(20)17-11-5-6-12-18(17)25/h2-13,25H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205074 (US9556132, 51 | process for preparing 1-(2-methoxy...) Show SMILES COc1ccccc1-c1ccccc1-c1nnnn1-c1ccccc1OC Show InChI InChI=1S/C21H18N4O2/c1-26-19-13-7-5-10-16(19)15-9-3-4-11-17(15)21-22-23-24-25(21)18-12-6-8-14-20(18)27-2/h3-14H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205058 (US9556132, 22 | process for preparing 1-(2-fluorop...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H12F4N4/c21-17-11-5-6-12-18(17)28-19(25-26-27-28)15-9-2-1-7-13(15)14-8-3-4-10-16(14)20(22,23)24/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205052 (US9556132, 15 | process for preparing 1-(2-fluorop...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C20H12F4N4O/c21-16-10-4-5-11-17(16)28-19(25-26-27-28)15-9-2-1-7-13(15)14-8-3-6-12-18(14)29-20(22,23)24/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM205004 (US9556132, 2 | process for preparing 2-{2-[1-(2-fl...) Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1I Show InChI InChI=1S/C13H8FIN4/c14-10-6-2-4-8-12(10)19-13(16-17-18-19)9-5-1-3-7-11(9)15/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	7.3	n/a
Saniona A/S US Patent					Assay Description Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...				US Patent US9556132 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z5T
					More data for this Ligand-Target Pair