Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359718 (US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...) Show SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F Show InChI InChI=1S/C19H21FN2O4S/c20-18-10-9-15(26-19(23)22-14-6-2-1-3-7-14)12-17(18)13-5-4-8-16(11-13)27(21,24)25/h4-5,8-12,14H,1-3,6-7H2,(H,22,23)(H2,21,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359719 (US10435355, Example 3 | US9822068, 3 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCC2)ccc1F Show InChI InChI=1S/C18H17FN2O3/c19-16-8-7-14(24-18(23)21-13-5-2-6-13)10-15(16)11-3-1-4-12(9-11)17(20)22/h1,3-4,7-10,13H,2,5-6H2,(H2,20,22)(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359724 (US10435355, Example 8 | US9822068, 8 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H22F2N2O4/c22-20(23)29-18-10-9-16(28-21(27)25-15-7-2-1-3-8-15)12-17(18)13-5-4-6-14(11-13)19(24)26/h4-6,9-12,15,20H,1-3,7-8H2,(H2,24,26)(H,25,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359717 (US10435355, Example 1 | US9822068, 1 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F Show InChI InChI=1S/C21H23FN2O3/c1-23-20(25)15-7-5-6-14(12-15)18-13-17(10-11-19(18)22)27-21(26)24-16-8-3-2-4-9-16/h5-7,10-13,16H,2-4,8-9H2,1H3,(H,23,25)(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359729 (US10435355, Example 13 | US9822068, 13 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1F Show InChI InChI=1S/C20H21FN2O3/c21-18-16(13-6-4-7-14(12-13)19(22)24)10-5-11-17(18)26-20(25)23-15-8-2-1-3-9-15/h4-7,10-12,15H,1-3,8-9H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359727 (US10435355, Example 11 | US9822068, 11 | [4-(diflu...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H23F2NO5S/c1-30(26,27)17-9-5-6-14(12-17)18-13-16(10-11-19(18)29-20(22)23)28-21(25)24-15-7-3-2-4-8-15/h5-6,9-13,15,20H,2-4,7-8H2,1H3,(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359721 (US10435355, Example 5 | US9822068, 5 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c20-17-9-8-15(25-19(24)22-14-6-1-2-7-14)11-16(17)12-4-3-5-13(10-12)18(21)23/h3-5,8-11,14H,1-2,6-7H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359725 (US10435355, Example 9 | US9822068, 9 | [4-(difluor...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C22H24F2N2O4/c1-25-20(27)15-7-5-6-14(12-15)18-13-17(10-11-19(18)30-21(23)24)29-22(28)26-16-8-3-2-4-9-16/h5-7,10-13,16,21H,2-4,8-9H2,1H3,(H,25,27)(H,26,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359720 (US10435355, Example 4 | US9822068, 4 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C20H21FN2O3/c1-22-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)21)26-20(25)23-15-7-2-3-8-15/h4-6,9-12,15H,2-3,7-8H2,1H3,(H,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359722 (US10435355, Example 6 | US9822068, 6 | [4-fluoro-3...) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c1-21-18(23)13-5-2-4-12(10-13)16-11-15(8-9-17(16)20)25-19(24)22-14-6-3-7-14/h2,4-5,8-11,14H,3,6-7H2,1H3,(H,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359726 (US10435355, Example 10 | US9822068, 10 | [4-(diflu...) Show SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C20H22F2N2O5S/c21-19(22)29-18-10-9-15(28-20(25)24-14-6-2-1-3-7-14)12-17(18)13-5-4-8-16(11-13)30(23,26)27/h4-5,8-12,14,19H,1-3,6-7H2,(H,24,25)(H2,23,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359723 (US10435355, Example 7 | US9822068, 7 | [4-fluoro-3...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F Show InChI InChI=1S/C20H22FNO4S/c1-27(24,25)17-9-5-6-14(12-17)18-13-16(10-11-19(18)21)26-20(23)22-15-7-3-2-4-8-15/h5-6,9-13,15H,2-4,7-8H2,1H3,(H,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair