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Compile Data Set for Download or QSAR

Found 167 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2368   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258159
PNG
(US9493448, 61 | US9845313, Example 61)
Show SMILES CCc1cc(c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H24FN5O3S/c1-3-14-11-20(31(28,29)26-21-8-9-23-13-24-21)16(22)12-19(14)30-18-6-4-5-15(18)17-7-10-25-27(17)2/h7-13,15,18H,3-6H2,1-2H3,(H,23,24,26)/t15-,18+/m1/s1
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n/an/a 2.60n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM362935
PNG
(5-Chloro-2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyr...)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)N([Na])c1cscn1 |r|
Show InChI InChI=1S/C18H17ClFN4O3S2.Na/c1-24-14(5-6-22-24)11-3-2-4-15(11)27-16-8-13(20)17(7-12(16)19)29(25,26)23-18-9-28-10-21-18;/h5-11,15H,2-4H2,1H3;/q-1;+1/t11-,15+;/m1./s1
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n/an/a 10n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258102
PNG
(US9493448, 4 | US9845313, Example 4)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1 |r|
Show InChI InChI=1S/C18H19F2N5O3S2/c1-25-14(6-7-22-25)11-4-2-3-5-15(11)28-16-8-13(20)17(9-12(16)19)30(26,27)24-18-21-10-23-29-18/h6-11,15H,2-5H2,1H3,(H,21,23,24)/t11-,15+/m1/s1
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n/an/a 12n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258219
PNG
(US9493448, 126 | US9597330, Example 37 | US9845313...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCC(F)(F)C[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H22F3N5O3S/c1-13-9-19(33(30,31)28-20-5-7-25-12-26-20)15(22)10-18(13)32-17-3-6-21(23,24)11-14(17)16-4-8-27-29(16)2/h4-5,7-10,12,14,17H,3,6,11H2,1-2H3,(H,25,26,28)/t14-,17+/m1/s1
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n/an/a 14n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258107
PNG
(US9493448, 9 | US9845313, Example 9)
Show SMILES Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1 |r|
Show InChI InChI=1S/C19H21F2N5O3S2/c1-26-15(7-8-23-26)12-5-3-2-4-6-16(12)29-17-9-14(21)18(10-13(17)20)31(27,28)25-19-22-11-24-30-19/h7-12,16H,2-6H2,1H3,(H,22,24,25)/t12-,16+/m1/s1
PDB

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n/an/a 14n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258146
PNG
(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H21ClFN5O3S/c1-27-16(6-9-25-27)13-4-2-3-5-17(13)30-18-11-15(22)19(10-14(18)21)31(28,29)26-20-7-8-23-12-24-20/h6-13,17H,2-5H2,1H3,(H,23,24,26)/t13-,17+/m1/s1
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n/an/a 16n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258106
PNG
(US9493448, 8 | US9845313, Example 8)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1 |r|
Show InChI InChI=1S/C17H17F2N5O3S2/c1-24-13(5-6-21-24)10-3-2-4-14(10)27-15-7-12(19)16(8-11(15)18)29(25,26)23-17-20-9-22-28-17/h5-10,14H,2-4H2,1H3,(H,20,22,23)/t10-,14+/m1/s1
PDB

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n/an/a 17n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258244
PNG
(US9493448, 152 | US9597330, Example 52 | US9845313...)
Show SMILES Fc1cc(O[C@H]2CC(F)(F)CC[C@@H]2c2cn[nH]c2)c(Cl)cc1S(=O)(=O)Nc1ccncn1 |r|
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n/an/a 17n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258146
PNG
(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H21ClFN5O3S/c1-27-16(6-9-25-27)13-4-2-3-5-17(13)30-18-11-15(22)19(10-14(18)21)31(28,29)26-20-7-8-23-12-24-20/h6-13,17H,2-5H2,1H3,(H,23,24,26)/t13-,17+/m1/s1
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n/an/a 17n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258164
PNG
(US9493448, 66 | US9845313, Example 66)
Show SMILES Cc1c(O[C@H]2CCCC[C@@H]2c2ccnn2C)ccc(c1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H24FN5O3S/c1-14-17(30-18-6-4-3-5-15(18)16-9-12-25-27(16)2)7-8-19(21(14)22)31(28,29)26-20-10-11-23-13-24-20/h7-13,15,18H,3-6H2,1-2H3,(H,23,24,26)/t15-,18+/m1/s1
PDB

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n/an/a 17n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258231
PNG
(US9493448, 138 | US9493448, 148 | US9597330, Examp...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCC[C@@H]1c1ccn[nH]1)S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 18n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258099
PNG
(US9493448, 1 | US9493448, 2 | US9493448, 3 | US949...)
Show SMILES Fc1cc(c(F)cc1O[C@H]1CCCC[C@@H]1c1ccccc1)S(=O)(=O)Nc1ncns1 |r|
Show InChI InChI=1S/C20H19F2N3O3S2/c21-15-11-19(30(26,27)25-20-23-12-24-29-20)16(22)10-18(15)28-17-9-5-4-8-14(17)13-6-2-1-3-7-13/h1-3,6-7,10-12,14,17H,4-5,8-9H2,(H,23,24,25)/t14-,17+/m1/s1
PDB

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n/an/a 20n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258146
PNG
(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H21ClFN5O3S/c1-27-16(6-9-25-27)13-4-2-3-5-17(13)30-18-11-15(22)19(10-14(18)21)31(28,29)26-20-7-8-23-12-24-20/h6-13,17H,2-5H2,1H3,(H,23,24,26)/t13-,17+/m1/s1
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n/an/a 20n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258233
PNG
(US9493448, 140 | US9493448, 150 | US9597330, Examp...)
Show SMILES Fc1cc(O[C@H]2CCC[C@@H]2c2ccn[nH]2)c(Cl)cc1S(=O)(=O)Nc1ccncn1 |r|
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n/an/a 21n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258220
PNG
(US9493448, 127 | US9493448, 143 | US9597330, Examp...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CC(F)(F)CC[C@@H]1c1cn[nH]c1)S(=O)(=O)Nc1ccncn1 |r|
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n/an/a 21n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258122
PNG
(US9493448, 24 | US9845313, Example 24)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccnc(F)n1 |r|
Show InChI InChI=1S/C19H18F3N5O3S/c1-27-14(5-8-24-27)11-3-2-4-15(11)30-16-9-13(21)17(10-12(16)20)31(28,29)26-18-6-7-23-19(22)25-18/h5-11,15H,2-4H2,1H3,(H,23,25,26)/t11-,15+/m1/s1
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n/an/a 23n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258141
PNG
(US9493448, 43 | US9597330, Example 10 | US9845313,...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H22FN5O3S/c1-13-10-19(30(27,28)25-20-7-8-22-12-23-20)15(21)11-18(13)29-17-5-3-4-14(17)16-6-9-24-26(16)2/h6-12,14,17H,3-5H2,1-2H3,(H,22,23,25)/t14-,17+/m1/s1
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n/an/a 24n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258231
PNG
(US9493448, 138 | US9493448, 148 | US9597330, Examp...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCC[C@@H]1c1ccn[nH]1)S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 24n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258238
PNG
(US9493448, 146 | US9597330, Example 49 | US9845313...)
Show SMILES Cn1nccc1[C@H]1CC(F)(F)C[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C19H17ClF3N5O3S/c1-28-14(2-5-26-28)11-8-19(22,23)9-16(11)31-15-7-13(21)17(6-12(15)20)32(29,30)27-18-3-4-24-10-25-18/h2-7,10-11,16H,8-9H2,1H3,(H,24,25,27)/t11-,16+/m1/s1
PDB

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n/an/a 24n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM363077
PNG
(5-Chloro-2-fluoro-4-{[(1S,2R)-2-(1H-pyrazol-5-yl)c...)
Show SMILES Fc1cc(O[C@H]2CCCC[C@@H]2c2ccn[nH]2)c(Cl)cc1S(=O)(=O)Nc1cc[nH]cn1 |r|
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n/an/a 28n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258113
PNG
(US9493448, 15 | US9845313, Example 15)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1nccs1 |r|
Show InChI InChI=1S/C18H18F2N4O3S2/c1-24-14(5-6-22-24)11-3-2-4-15(11)27-16-9-13(20)17(10-12(16)19)29(25,26)23-18-21-7-8-28-18/h5-11,15H,2-4H2,1H3,(H,21,23)/t11-,15+/m1/s1
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n/an/a 28n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM301817
PNG
(5-Chloro-2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyr...)
Show SMILES Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(c(F)c1)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H23F2N5O3S/c1-28-18(7-10-26-28)15-5-3-2-4-6-19(15)31-14-11-16(22)21(17(23)12-14)32(29,30)27-20-8-9-24-13-25-20/h7-13,15,19H,2-6H2,1H3,(H,24,25,27)/t15-,19+/m1/s1
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n/an/a 28n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258246
PNG
(US9493448, 155 | US9597330, Example 54 | US9845313...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CC(F)(F)CC[C@@H]1c1ccn[nH]1)S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 28n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM362934
PNG
(5-Chloro-2-fluoro-4-{[(1S*,2R*)-2-(1-methyl-1H-pyr...)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)N([Na])c1cscn1 |r|
Show InChI InChI=1S/C19H19ClFN4O3S2.Na/c1-25-15(6-7-23-25)12-4-2-3-5-16(12)28-17-9-14(21)18(8-13(17)20)30(26,27)24-19-10-29-11-22-19;/h6-12,16H,2-5H2,1H3;/q-1;+1/t12-,16+;/m1./s1
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n/an/a 30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258205
PNG
(US9493448, 111 | US9845313, Example 111)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(c(F)c1)S(=O)(=O)Nc1ccnc(F)n1 |r|
Show InChI InChI=1S/C19H18F3N5O3S/c1-27-15(5-8-24-27)12-3-2-4-16(12)30-11-9-13(20)18(14(21)10-11)31(28,29)26-17-6-7-23-19(22)25-17/h5-10,12,16H,2-4H2,1H3,(H,23,25,26)/t12-,16+/m1/s1
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n/an/a 30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258144
PNG
(US9493448, 46 | US9597330, Example 11 | US9845313,...)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(c(F)c1)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H21F2N5O3S/c1-27-17(6-9-25-27)14-4-2-3-5-18(14)30-13-10-15(21)20(16(22)11-13)31(28,29)26-19-7-8-23-12-24-19/h6-12,14,18H,2-5H2,1H3,(H,23,24,26)/t14-,18+/m1/s1
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n/an/a 30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258185
PNG
(US9493448, 137 | US9493448, 90 | US9597330, Exampl...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CC(F)(F)CC[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H22F3N5O3S/c1-13-9-19(33(30,31)28-20-5-7-25-12-26-20)15(22)10-17(13)32-18-11-21(23,24)6-3-14(18)16-4-8-27-29(16)2/h4-5,7-10,12,14,18H,3,6,11H2,1-2H3,(H,25,26,28)/t14-,18+/m1/s1
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n/an/a 30n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258162
PNG
(US9493448, 64 | US9597330, Example 21 | US9845313,...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H24FN5O3S/c1-14-11-20(31(28,29)26-21-8-9-23-13-24-21)16(22)12-19(14)30-18-6-4-3-5-15(18)17-7-10-25-27(17)2/h7-13,15,18H,3-6H2,1-2H3,(H,23,24,26)/t15-,18+/m1/s1
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n/an/a 31n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258157
PNG
(US9493448, 59 | US9597330, Example 18 | US9845313,...)
Show SMILES CCn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(c(F)c1)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H23F2N5O3S/c1-2-28-18(7-10-26-28)15-5-3-4-6-19(15)31-14-11-16(22)21(17(23)12-14)32(29,30)27-20-8-9-24-13-25-20/h7-13,15,19H,2-6H2,1H3,(H,24,25,27)/t15-,19+/m1/s1
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n/an/a 31n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258176
PNG
(US9493448, 172 | US9493448, 81 | US9597330, Exampl...)
Show SMILES Cc1cc(c(F)cc1O[C@H]1CCCC[C@@H]1c1cn[nH]c1)S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 34n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258233
PNG
(US9493448, 140 | US9493448, 150 | US9597330, Examp...)
Show SMILES Fc1cc(O[C@H]2CCC[C@@H]2c2ccn[nH]2)c(Cl)cc1S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 34n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258227
PNG
(US9493448, 134 | US9845313, Example 134)
Show SMILES Cn1nccc1[C@H]1CCC(F)(F)C[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nncs1 |r|
Show InChI InChI=1S/C18H17ClF3N5O3S2/c1-27-13(3-5-24-27)10-2-4-18(21,22)8-15(10)30-14-7-12(20)16(6-11(14)19)32(28,29)26-17-25-23-9-31-17/h3,5-7,9-10,15H,2,4,8H2,1H3,(H,25,26)/t10-,15+/m1/s1
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n/an/a 34n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258191
PNG
(US9493448, 97 | US9845313, Example 97)
Show SMILES Cn1nccc1[C@H]1C[C@H](C[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1)OCc1ccccc1 |r|
Show InChI InChI=1S/C26H25F2N5O4S/c1-33-22(7-10-31-33)19-11-18(36-15-17-5-3-2-4-6-17)12-23(19)37-24-13-21(28)25(14-20(24)27)38(34,35)32-26-8-9-29-16-30-26/h2-10,13-14,16,18-19,23H,11-12,15H2,1H3,(H,29,30,32)/t18-,19-,23+/m1/s1
PDB

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n/an/a 34n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258232
PNG
(US9493448, 139 | US9597330, Example 45 | US9845313...)
Show SMILES Fc1cc(O[C@H]2CCC[C@@H]2c2ccn[nH]2)cc(F)c1S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 35n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258179
PNG
(US9493448, 84 | US9597330, Example 26 | US9845313,...)
Show SMILES Cc1c(O[C@H]2CC(F)(F)CC[C@@H]2c2ccnn2C)ccc(c1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H22F3N5O3S/c1-13-16(3-4-18(20(13)22)33(30,31)28-19-7-9-25-12-26-19)32-17-11-21(23,24)8-5-14(17)15-6-10-27-29(15)2/h3-4,6-7,9-10,12,14,17H,5,8,11H2,1-2H3,(H,25,26,28)/t14-,17+/m1/s1
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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258170
PNG
(US9493448, 72 | US9597330, Example 23 | US9845313,...)
Show SMILES Cn1nccc1[C@H]1CCC(C)(C)C[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C22H25F2N5O3S/c1-22(2)7-4-14(17-5-9-27-29(17)3)19(12-22)32-18-10-16(24)20(11-15(18)23)33(30,31)28-21-6-8-25-13-26-21/h5-6,8-11,13-14,19H,4,7,12H2,1-3H3,(H,25,26,28)/t14-,19+/m1/s1
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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258181
PNG
(US9493448, 86 | US9845313, Example 86)
Show SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nncs1 |r|
Show InChI InChI=1S/C18H19ClFN5O3S2/c1-25-14(6-7-22-25)11-4-2-3-5-15(11)28-16-9-13(20)17(8-12(16)19)30(26,27)24-18-23-21-10-29-18/h6-11,15H,2-5H2,1H3,(H,23,24)/t11-,15+/m1/s1
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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258145
PNG
(US9493448, 102 | US9493448, 47 | US9597330, Exampl...)
Show SMILES Cn1nccc1[C@H]1CCC(F)(F)C[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H19F4N5O3S/c1-29-15(3-7-27-29)12-2-5-20(23,24)10-17(12)32-16-8-14(22)18(9-13(16)21)33(30,31)28-19-4-6-25-11-26-19/h3-4,6-9,11-12,17H,2,5,10H2,1H3,(H,25,26,28)/t12-,17+/m1/s1
PDB

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n/an/a 36n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258158
PNG
(US9493448, 60 | US9845313, Example 60)
Show SMILES Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H23ClFN5O3S/c1-28-17(7-10-26-28)14-5-3-2-4-6-18(14)31-19-12-16(23)20(11-15(19)22)32(29,30)27-21-8-9-24-13-25-21/h7-14,18H,2-6H2,1H3,(H,24,25,27)/t14-,18+/m1/s1
PDB

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n/an/a 37n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258152
PNG
(US9493448, 54 | US9597330, Example 16 | US9845313,...)
Show SMILES Cc1cc(ccc1O[C@H]1CCCC[C@@H]1c1ccnn1C)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H25N5O3S/c1-15-13-16(30(27,28)25-21-10-11-22-14-23-21)7-8-19(15)29-20-6-4-3-5-17(20)18-9-12-24-26(18)2/h7-14,17,20H,3-6H2,1-2H3,(H,22,23,25)/t17-,20+/m1/s1
PDB

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n/an/a 39n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258153
PNG
(US9493448, 55 | US9845313, Example 55)
Show SMILES Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C22H24N6O3S/c1-28-19(9-12-26-28)18-5-3-2-4-6-21(18)31-20-8-7-17(13-16(20)14-23)32(29,30)27-22-10-11-24-15-25-22/h7-13,15,18,21H,2-6H2,1H3,(H,24,25,27)/t18-,21+/m1/s1
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n/an/a 39n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258252
PNG
(US9493448, 161 | US9493448, 165 | US9597330, Examp...)
Show SMILES Cn1nccc1[C@H]1C[C@H](O)CC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C20H21ClFN5O4S/c1-27-16(4-7-25-27)13-8-12(28)2-3-17(13)31-18-10-15(22)19(9-14(18)21)32(29,30)26-20-5-6-23-11-24-20/h4-7,9-13,17,28H,2-3,8H2,1H3,(H,23,24,26)/t12-,13-,17+/m1/s1
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n/an/a 40n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258247
PNG
(US9493448, 156 | US9597330, Example 55 | US9845313...)
Show SMILES Fc1cc(O[C@H]2CC(F)(F)CC[C@@H]2c2ccn[nH]2)c(Cl)cc1S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 41n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258201
PNG
(US9493448, 107 | US9597330, Example 31 | US9845313...)
Show SMILES Cn1nccc1[C@H]1CC(F)(F)C[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C19H17F4N5O3S/c1-28-14(2-5-26-28)11-8-19(22,23)9-16(11)31-15-6-13(21)17(7-12(15)20)32(29,30)27-18-3-4-24-10-25-18/h2-7,10-11,16H,8-9H2,1H3,(H,24,25,27)/t11-,16+/m1/s1
PDB

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n/an/a 42n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258189
PNG
(US9493448, 171 | US9493448, 94 | US9597330, Exampl...)
Show SMILES Fc1cc(O[C@H]2CCCC[C@@H]2c2cn[nH]c2)cc(F)c1S(=O)(=O)Nc1ccncn1 |r|
PDB

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n/an/a 43n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258165
PNG
(US9493448, 67 | US9597330, Example 22 | US9845313,...)
Show SMILES Cn1nccc1[C@H]1CC(C)(C)CC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C22H25F2N5O3S/c1-22(2)7-4-18(14(12-22)17-5-9-27-29(17)3)32-19-10-16(24)20(11-15(19)23)33(30,31)28-21-6-8-25-13-26-21/h5-6,8-11,13-14,18H,4,7,12H2,1-3H3,(H,25,26,28)/t14-,18+/m1/s1
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n/an/a 43n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258125
PNG
(US9493448, 27 | US9597330, Example 4 | US9845313, ...)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(c(F)c1)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C19H19F2N5O3S/c1-26-16(5-8-24-26)13-3-2-4-17(13)29-12-9-14(20)19(15(21)10-12)30(27,28)25-18-6-7-22-11-23-18/h5-11,13,17H,2-4H2,1H3,(H,22,23,25)/t13-,17+/m1/s1
PDB

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n/an/a 43n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258118
PNG
(US9493448, 20 | US9597330, Example 2 | US9845313, ...)
Show SMILES Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C19H19ClFN5O3S/c1-26-15(5-8-24-26)12-3-2-4-16(12)29-17-10-14(21)18(9-13(17)20)30(27,28)25-19-6-7-22-11-23-19/h5-12,16H,2-4H2,1H3,(H,22,23,25)/t12-,16+/m1/s1
PDB

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n/an/a 45n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258192
PNG
(US9493448, 98 | US9845313, Example 98)
Show SMILES Cn1nccc1[C@H]1C[C@@H](C[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1)OCc1ccccc1 |r|
Show InChI InChI=1S/C26H25F2N5O4S/c1-33-22(7-10-31-33)19-11-18(36-15-17-5-3-2-4-6-17)12-23(19)37-24-13-21(28)25(14-20(24)27)38(34,35)32-26-8-9-29-16-30-26/h2-10,13-14,16,18-19,23H,11-12,15H2,1H3,(H,29,30,32)/t18-,19+,23-/m0/s1
PDB

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n/an/a 46n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM258126
PNG
(US9493448, 28 | US9597330, Example 5 | US9845313, ...)
Show SMILES CCn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1 |r|
Show InChI InChI=1S/C21H23F2N5O3S/c1-2-28-17(7-10-26-28)14-5-3-4-6-18(14)31-19-11-16(23)20(12-15(19)22)32(29,30)27-21-8-9-24-13-25-21/h7-14,18H,2-6H2,1H3,(H,24,25,27)/t14-,18+/m1/s1
PDB

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n/an/a 46n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...

US Patent US9845313 (2017)


BindingDB Entry DOI: 10.7270/Q25141H5
More data for this
Ligand-Target Pair
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