Compile Data Set for Download or QSAR

Found 143 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375724 (US10301323, Compound D1 | US9908899, Compound D1) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1 Show InChI InChI=1S/C21H20N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-13,15-16H,14,22H2,(H,24,26)/b9-6+,13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375724 (US10301323, Compound D1 | US9908899, Compound D1) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1 Show InChI InChI=1S/C21H20N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-13,15-16H,14,22H2,(H,24,26)/b9-6+,13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375724 (US10301323, Compound D1 | US9908899, Compound D1) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1 Show InChI InChI=1S/C21H20N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-13,15-16H,14,22H2,(H,24,26)/b9-6+,13-12+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50254780 (CHEMBL4078477 | US10301323, Compound D2 | US990889...) Show SMILES Nc1cc(F)ccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1 Show InChI InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11,13-15H,12,23H2,(H,25,27)/b7-4+,11-8+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375726 (US10301323, Compound D3 | US9908899, Compound D3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O2/c21-18-8-4-5-9-19(18)23-20(25)11-10-16-14-22-24(15-16)12-13-26-17-6-2-1-3-7-17/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375726 (US10301323, Compound D3 | US9908899, Compound D3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O2/c21-18-8-4-5-9-19(18)23-20(25)11-10-16-14-22-24(15-16)12-13-26-17-6-2-1-3-7-17/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375726 (US10301323, Compound D3 | US9908899, Compound D3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O2/c21-18-8-4-5-9-19(18)23-20(25)11-10-16-14-22-24(15-16)12-13-26-17-6-2-1-3-7-17/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375727 (US10301323, Compound D9 | US9908899, Compound D9) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCCc2ccccc2)c1 Show InChI InChI=1S/C22H24N4O/c23-20-11-4-5-12-21(20)25-22(27)14-13-19-16-24-26(17-19)15-7-6-10-18-8-2-1-3-9-18/h1-5,8-9,11-14,16-17H,6-7,10,15,23H2,(H,25,27)/b14-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375727 (US10301323, Compound D9 | US9908899, Compound D9) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCCc2ccccc2)c1 Show InChI InChI=1S/C22H24N4O/c23-20-11-4-5-12-21(20)25-22(27)14-13-19-16-24-26(17-19)15-7-6-10-18-8-2-1-3-9-18/h1-5,8-9,11-14,16-17H,6-7,10,15,23H2,(H,25,27)/b14-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375727 (US10301323, Compound D9 | US9908899, Compound D9) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCCc2ccccc2)c1 Show InChI InChI=1S/C22H24N4O/c23-20-11-4-5-12-21(20)25-22(27)14-13-19-16-24-26(17-19)15-7-6-10-18-8-2-1-3-9-18/h1-5,8-9,11-14,16-17H,6-7,10,15,23H2,(H,25,27)/b14-13+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375728 (US10301323, Compound B6 | US9908899, Compound B6) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccc(F)cc2)c1 Show InChI InChI=1S/C20H19FN4O2/c21-16-6-8-17(9-7-16)27-12-11-25-14-15(13-23-25)5-10-20(26)24-19-4-2-1-3-18(19)22/h1-10,13-14H,11-12,22H2,(H,24,26)/b10-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375728 (US10301323, Compound B6 | US9908899, Compound B6) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccc(F)cc2)c1 Show InChI InChI=1S/C20H19FN4O2/c21-16-6-8-17(9-7-16)27-12-11-25-14-15(13-23-25)5-10-20(26)24-19-4-2-1-3-18(19)22/h1-10,13-14H,11-12,22H2,(H,24,26)/b10-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375728 (US10301323, Compound B6 | US9908899, Compound B6) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccc(F)cc2)c1 Show InChI InChI=1S/C20H19FN4O2/c21-16-6-8-17(9-7-16)27-12-11-25-14-15(13-23-25)5-10-20(26)24-19-4-2-1-3-18(19)22/h1-10,13-14H,11-12,22H2,(H,24,26)/b10-5+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375733 (US10301323, Compound B2 | US9908899, Compound B2) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccc(F)cc2)c1 Show InChI InChI=1S/C21H19FN4O/c22-18-10-7-16(8-11-18)4-3-13-26-15-17(14-24-26)9-12-21(27)25-20-6-2-1-5-19(20)23/h1-12,14-15H,13,23H2,(H,25,27)/b4-3+,12-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375733 (US10301323, Compound B2 | US9908899, Compound B2) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccc(F)cc2)c1 Show InChI InChI=1S/C21H19FN4O/c22-18-10-7-16(8-11-18)4-3-13-26-15-17(14-24-26)9-12-21(27)25-20-6-2-1-5-19(20)23/h1-12,14-15H,13,23H2,(H,25,27)/b4-3+,12-9+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375734 (US10301323, Compound B4 | US9908899, Compound B4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C21H19F3N4O2/c22-21(23,24)16-6-8-17(9-7-16)30-12-11-28-14-15(13-26-28)5-10-20(29)27-19-4-2-1-3-18(19)25/h1-10,13-14H,11-12,25H2,(H,27,29)/b10-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375734 (US10301323, Compound B4 | US9908899, Compound B4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C21H19F3N4O2/c22-21(23,24)16-6-8-17(9-7-16)30-12-11-28-14-15(13-26-28)5-10-20(29)27-19-4-2-1-3-18(19)25/h1-10,13-14H,11-12,25H2,(H,27,29)/b10-5+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375735 (US10301323, Compound B3 | US9908899, Compound B3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(F)c2)c1 Show InChI InChI=1S/C20H18F2N4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375735 (US10301323, Compound B3 | US9908899, Compound B3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(F)c2)c1 Show InChI InChI=1S/C20H18F2N4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375735 (US10301323, Compound B3 | US9908899, Compound B3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(F)c2)c1 Show InChI InChI=1S/C20H18F2N4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375736 (US10301323, Compound D16 | US9908899, Compound D16) Show SMILES Nc1cc(F)ccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H19FN4O2/c21-16-7-8-19(18(22)12-16)24-20(26)9-6-15-13-23-25(14-15)10-11-27-17-4-2-1-3-5-17/h1-9,12-14H,10-11,22H2,(H,24,26)/b9-6+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375737 (US10301323, Compound B5 | US9908899, Compound B5) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(Cl)c2)c1 Show InChI InChI=1S/C20H18ClFN4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375737 (US10301323, Compound B5 | US9908899, Compound B5) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(Cl)c2)c1 Show InChI InChI=1S/C20H18ClFN4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375737 (US10301323, Compound B5 | US9908899, Compound B5) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2cc(F)cc(Cl)c2)c1 Show InChI InChI=1S/C20H18ClFN4O2/c21-15-9-16(22)11-17(10-15)28-8-7-26-13-14(12-24-26)5-6-20(27)25-19-4-2-1-3-18(19)23/h1-6,9-13H,7-8,23H2,(H,25,27)/b6-5+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375738 (US10301323, Compound A12 | US9908899, Compound A12) Show SMILES Cn1cnc(\C=C\C(=O)Nc2ccccc2N)c1 Show InChI InChI=1S/C13H14N4O/c1-17-8-10(15-9-17)6-7-13(18)16-12-5-3-2-4-11(12)14/h2-9H,14H2,1H3,(H,16,18)/b7-6+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375739 (US10301323, Compound D4 | US9908899, Compound D4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C19H18N4O/c20-17-8-4-5-9-18(17)22-19(24)11-10-16-12-21-23(14-16)13-15-6-2-1-3-7-15/h1-12,14H,13,20H2,(H,22,24)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375739 (US10301323, Compound D4 | US9908899, Compound D4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C19H18N4O/c20-17-8-4-5-9-18(17)22-19(24)11-10-16-12-21-23(14-16)13-15-6-2-1-3-7-15/h1-12,14H,13,20H2,(H,22,24)/b11-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375740 (US10301323, Compound D7 | US9908899, Compound D7) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O/c21-18-8-4-5-9-19(18)23-20(25)11-10-17-14-22-24(15-17)13-12-16-6-2-1-3-7-16/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375740 (US10301323, Compound D7 | US9908899, Compound D7) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O/c21-18-8-4-5-9-19(18)23-20(25)11-10-17-14-22-24(15-17)13-12-16-6-2-1-3-7-16/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375741 (US10301323, Compound D8 | US9908899, Compound D8) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-13,15-16H,6,9,14,22H2,(H,24,26)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375741 (US10301323, Compound D8 | US9908899, Compound D8) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-13,15-16H,6,9,14,22H2,(H,24,26)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375741 (US10301323, Compound D8 | US9908899, Compound D8) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O/c22-19-10-4-5-11-20(19)24-21(26)13-12-18-15-23-25(16-18)14-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-13,15-16H,6,9,14,22H2,(H,24,26)/b13-12+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375742 (US10301323, Compound D14 | US9908899, Compound D14) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-8-4-5-9-20(19)24-21(26)11-10-18-14-23-25(15-18)12-13-27-16-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16,22H2,(H,24,26)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375742 (US10301323, Compound D14 | US9908899, Compound D14) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-8-4-5-9-20(19)24-21(26)11-10-18-14-23-25(15-18)12-13-27-16-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16,22H2,(H,24,26)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375742 (US10301323, Compound D14 | US9908899, Compound D14) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOCc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-8-4-5-9-20(19)24-21(26)11-10-18-14-23-25(15-18)12-13-27-16-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16,22H2,(H,24,26)/b11-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375743 (US10301323, Compound D11 | US9908899, Compound D11) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CC\C=C\c2ccccc2)c1 Show InChI InChI=1S/C22H22N4O/c23-20-11-4-5-12-21(20)25-22(27)14-13-19-16-24-26(17-19)15-7-6-10-18-8-2-1-3-9-18/h1-6,8-14,16-17H,7,15,23H2,(H,25,27)/b10-6+,14-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375743 (US10301323, Compound D11 | US9908899, Compound D11) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CC\C=C\c2ccccc2)c1 Show InChI InChI=1S/C22H22N4O/c23-20-11-4-5-12-21(20)25-22(27)14-13-19-16-24-26(17-19)15-7-6-10-18-8-2-1-3-9-18/h1-6,8-14,16-17H,7,15,23H2,(H,25,27)/b10-6+,14-13+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375744 (US10301323, Compound D5 | US9908899, Compound D5) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C19H17FN4O/c20-16-8-5-14(6-9-16)12-24-13-15(11-22-24)7-10-19(25)23-18-4-2-1-3-17(18)21/h1-11,13H,12,21H2,(H,23,25)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375744 (US10301323, Compound D5 | US9908899, Compound D5) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C19H17FN4O/c20-16-8-5-14(6-9-16)12-24-13-15(11-22-24)7-10-19(25)23-18-4-2-1-3-17(18)21/h1-11,13H,12,21H2,(H,23,25)/b10-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375745 (US10301323, Compound D12 | US9908899, Compound D12) Show SMILES CN(CCCn1cc(\C=C\C(=O)Nc2ccccc2N)cn1)c1ccccc1 Show InChI InChI=1S/C22H25N5O/c1-26(19-8-3-2-4-9-19)14-7-15-27-17-18(16-24-27)12-13-22(28)25-21-11-6-5-10-20(21)23/h2-6,8-13,16-17H,7,14-15,23H2,1H3,(H,25,28)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375745 (US10301323, Compound D12 | US9908899, Compound D12) Show SMILES CN(CCCn1cc(\C=C\C(=O)Nc2ccccc2N)cn1)c1ccccc1 Show InChI InChI=1S/C22H25N5O/c1-26(19-8-3-2-4-9-19)14-7-15-27-17-18(16-24-27)12-13-22(28)25-21-11-6-5-10-20(21)23/h2-6,8-13,16-17H,7,14-15,23H2,1H3,(H,25,28)/b13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375745 (US10301323, Compound D12 | US9908899, Compound D12) Show SMILES CN(CCCn1cc(\C=C\C(=O)Nc2ccccc2N)cn1)c1ccccc1 Show InChI InChI=1S/C22H25N5O/c1-26(19-8-3-2-4-9-19)14-7-15-27-17-18(16-24-27)12-13-22(28)25-21-11-6-5-10-20(21)23/h2-6,8-13,16-17H,7,14-15,23H2,1H3,(H,25,28)/b13-12+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375746 (US10301323, Compound D13 | US9908899, Compound D13) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCc2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C22H21N5O/c23-19-6-2-4-8-21(19)26-22(28)10-9-16-13-25-27(15-16)12-11-17-14-24-20-7-3-1-5-18(17)20/h1-10,13-15,24H,11-12,23H2,(H,26,28)/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375746 (US10301323, Compound D13 | US9908899, Compound D13) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCc2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C22H21N5O/c23-19-6-2-4-8-21(19)26-22(28)10-9-16-13-25-27(15-16)12-11-17-14-24-20-7-3-1-5-18(17)20/h1-10,13-15,24H,11-12,23H2,(H,26,28)/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375746 (US10301323, Compound D13 | US9908899, Compound D13) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCc2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C22H21N5O/c23-19-6-2-4-8-21(19)26-22(28)10-9-16-13-25-27(15-16)12-11-17-14-24-20-7-3-1-5-18(17)20/h1-10,13-15,24H,11-12,23H2,(H,26,28)/b10-9+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375747 (US10301323, Compound D15 | US9908899, Compound D15) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCOc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-9-4-5-10-20(19)24-21(26)12-11-17-15-23-25(16-17)13-6-14-27-18-7-2-1-3-8-18/h1-5,7-12,15-16H,6,13-14,22H2,(H,24,26)/b12-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375747 (US10301323, Compound D15 | US9908899, Compound D15) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCOc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-9-4-5-10-20(19)24-21(26)12-11-17-15-23-25(16-17)13-6-14-27-18-7-2-1-3-8-18/h1-5,7-12,15-16H,6,13-14,22H2,(H,24,26)/b12-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375747 (US10301323, Compound D15 | US9908899, Compound D15) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCCOc2ccccc2)c1 Show InChI InChI=1S/C21H22N4O2/c22-19-9-4-5-10-20(19)24-21(26)12-11-17-15-23-25(16-17)13-6-14-27-18-7-2-1-3-8-18/h1-5,7-12,15-16H,6,13-14,22H2,(H,24,26)/b12-11+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375748 (US10301323, Compound D10 | US9908899, Compound D10) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CC(F)(F)c2ccccc2)c1 Show InChI InChI=1S/C20H18F2N4O/c21-20(22,16-6-2-1-3-7-16)14-26-13-15(12-24-26)10-11-19(27)25-18-9-5-4-8-17(18)23/h1-13H,14,23H2,(H,25,27)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM375748 (US10301323, Compound D10 | US9908899, Compound D10) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CC(F)(F)c2ccccc2)c1 Show InChI InChI=1S/C20H18F2N4O/c21-20(22,16-6-2-1-3-7-16)14-26-13-15(12-24-26)10-11-19(27)25-18-9-5-4-8-17(18)23/h1-13H,14,23H2,(H,25,27)/b11-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair

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