Compile Data Set for Download or QSAR

Found 23 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 3075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27542 (4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...) Show SMILES O=C(N1CCNCC1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C20H20N4O2/c25-19-17-7-2-1-6-16(17)18(22-23-19)13-14-4-3-5-15(12-14)20(26)24-10-8-21-9-11-24/h1-7,12,21H,8-11,13H2,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27662 (4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C29H28N4O4/c1-20(37-23-10-3-2-4-11-23)28(35)32-14-16-33(17-15-32)29(36)22-9-7-8-21(18-22)19-26-24-12-5-6-13-25(24)27(34)31-30-26/h2-13,18,20H,14-17,19H2,1H3,(H,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27661 (4-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...) Show SMILES O=C(C1CCCC1)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C26H28N4O3/c31-24-22-11-4-3-10-21(22)23(27-28-24)17-18-6-5-9-20(16-18)26(33)30-14-12-29(13-15-30)25(32)19-7-1-2-8-19/h3-6,9-11,16,19H,1-2,7-8,12-15,17H2,(H,28,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27680 (2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...) Show SMILES NC(=O)c1cc(F)ccc1OCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C25H27F2N3O4/c26-18-6-8-22(20(14-18)23(28)31)34-15-16-5-7-21(27)19(13-16)25(33)30-11-9-29(10-12-30)24(32)17-3-1-2-4-17/h5-8,13-14,17H,1-4,9-12,15H2,(H2,28,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27681 (5-fluoro-2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)pi...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(COc2ccc(F)cc2C(N)=O)ccc1F Show InChI InChI=1S/C28H27F2N3O5/c1-18(38-21-5-3-2-4-6-21)27(35)32-11-13-33(14-12-32)28(36)22-15-19(7-9-24(22)30)17-37-25-10-8-20(29)16-23(25)26(31)34/h2-10,15-16,18H,11-14,17H2,1H3,(H2,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27663 (2-{[3-(piperazin-1-ylcarbonyl)phenyl]methoxy}benza...) Show SMILES NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H21N3O3/c20-18(23)16-6-1-2-7-17(16)25-13-14-4-3-5-15(12-14)19(24)22-10-8-21-9-11-22/h1-7,12,21H,8-11,13H2,(H2,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27674 (2-[2-(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(CCOc2ccccc2C(N)=O)ccc1F Show InChI InChI=1S/C29H30FN3O5/c1-20(38-22-7-3-2-4-8-22)28(35)32-14-16-33(17-15-32)29(36)24-19-21(11-12-25(24)30)13-18-37-26-10-6-5-9-23(26)27(31)34/h2-12,19-20H,13-18H2,1H3,(H2,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27666 (2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...) Show SMILES NC(=O)c1ccccc1OCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C25H28FN3O4/c26-21-10-9-17(16-33-22-8-4-3-7-19(22)23(27)30)15-20(21)25(32)29-13-11-28(12-14-29)24(31)18-5-1-2-6-18/h3-4,7-10,15,18H,1-2,5-6,11-14,16H2,(H2,27,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27675 (5-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...) Show SMILES NC(=O)c1cc(F)ccc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H19F2N3O3/c20-13-2-4-17(15(10-13)18(22)25)27-11-12-1-3-16(21)14(9-12)19(26)24-7-5-23-6-8-24/h1-4,9-10,23H,5-8,11H2,(H2,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27667 (2-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(COc2ccccc2C(N)=O)c1 Show InChI InChI=1S/C28H29N3O5/c1-20(36-23-10-3-2-4-11-23)27(33)30-14-16-31(17-15-30)28(34)22-9-7-8-21(18-22)19-35-25-13-6-5-12-24(25)26(29)32/h2-13,18,20H,14-17,19H2,1H3,(H2,29,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27668 (2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin-1...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(COc2ccccc2C(N)=O)ccc1F Show InChI InChI=1S/C28H28FN3O5/c1-19(37-21-7-3-2-4-8-21)27(34)31-13-15-32(16-14-31)28(35)23-17-20(11-12-24(23)29)18-36-25-10-6-5-9-22(25)26(30)33/h2-12,17,19H,13-16,18H2,1H3,(H2,30,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27664 (2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...) Show SMILES NC(=O)c1ccccc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H20FN3O3/c20-16-6-5-13(11-15(16)19(25)23-9-7-22-8-10-23)12-26-17-4-2-1-3-14(17)18(21)24/h1-6,11,22H,7-10,12H2,(H2,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27672 (2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...) Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C26H30FN3O4/c27-22-10-9-18(11-16-34-23-8-4-3-7-20(23)24(28)31)17-21(22)26(33)30-14-12-29(13-15-30)25(32)19-5-1-2-6-19/h3-4,7-10,17,19H,1-2,5-6,11-16H2,(H2,28,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27665 (2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...) Show SMILES NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C25H29N3O4/c26-23(29)21-10-3-4-11-22(21)32-17-18-6-5-9-20(16-18)25(31)28-14-12-27(13-15-28)24(30)19-7-1-2-8-19/h3-6,9-11,16,19H,1-2,7-8,12-15,17H2,(H2,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27671 (2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...) Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C26H31N3O4/c27-24(30)22-10-3-4-11-23(22)33-17-12-19-6-5-9-21(18-19)26(32)29-15-13-28(14-16-29)25(31)20-7-1-2-8-20/h3-6,9-11,18,20H,1-2,7-8,12-17H2,(H2,27,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27673 (2-[2-(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]car...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(CCOc2ccccc2C(N)=O)c1 Show InChI InChI=1S/C29H31N3O5/c1-21(37-24-10-3-2-4-11-24)28(34)31-15-17-32(18-16-31)29(35)23-9-7-8-22(20-23)14-19-36-26-13-6-5-12-25(26)27(30)33/h2-13,20-21H,14-19H2,1H3,(H2,30,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27676 (4,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...) Show SMILES NC(=O)c1cc(F)c(F)cc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H18F3N3O3/c20-14-2-1-11(7-12(14)19(27)25-5-3-24-4-6-25)10-28-17-9-16(22)15(21)8-13(17)18(23)26/h1-2,7-9,24H,3-6,10H2,(H2,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27677 (4-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...) Show SMILES NC(=O)c1ccc(F)cc1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H19F2N3O3/c20-13-2-3-14(18(22)25)17(10-13)27-11-12-1-4-16(21)15(9-12)19(26)24-7-5-23-6-8-24/h1-4,9-10,23H,5-8,11H2,(H2,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27660 (4-Benzyl-2H-phthalazin-1-one | 4-benzyl-1,2-dihydr...) Show SMILES O=c1[nH]nc(Cc2ccccc2)c2ccccc12 Show InChI InChI=1S/C15H12N2O/c18-15-13-9-5-4-8-12(13)14(16-17-15)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27669 (2-{2-[3-(piperazin-1-ylcarbonyl)phenyl]ethoxy}benz...) Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C20H23N3O3/c21-19(24)17-6-1-2-7-18(17)26-13-8-15-4-3-5-16(14-15)20(25)23-11-9-22-10-12-23/h1-7,14,22H,8-13H2,(H2,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27678 (3,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...) Show SMILES NC(=O)c1cc(F)cc(F)c1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H18F3N3O3/c20-12-8-14(18(23)26)17(16(22)9-12)28-10-11-1-2-15(21)13(7-11)19(27)25-5-3-24-4-6-25/h1-2,7-9,24H,3-6,10H2,(H2,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27670 (2-{2-[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]et...) Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C20H22FN3O3/c21-17-6-5-14(13-16(17)20(26)24-10-8-23-9-11-24)7-12-27-18-4-2-1-3-15(18)19(22)25/h1-6,13,23H,7-12H2,(H2,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27679 (3,6-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...) Show SMILES NC(=O)c1c(F)ccc(F)c1OCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C19H18F3N3O3/c20-13-2-1-11(9-12(13)19(27)25-7-5-24-6-8-25)10-28-17-15(22)4-3-14(21)16(17)18(23)26/h1-4,9,24H,5-8,10H2,(H2,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair