BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50032151
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM19441 (2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
University of Delaware Curated by ChEMBL					Assay Description Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivati...				Bioorg Med Chem Lett 20: 5258-61 (2010) Article DOI: 10.1016/j.bmcl.2010.06.151 BindingDB Entry DOI: 10.7270/Q2GF0TPB
University of Delaware Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM50324966 (3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
University of Delaware Curated by ChEMBL					Assay Description Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivati...				Bioorg Med Chem Lett 20: 5258-61 (2010) Article DOI: 10.1016/j.bmcl.2010.06.151 BindingDB Entry DOI: 10.7270/Q2GF0TPB
University of Delaware Curated by ChEMBL					More data for this Ligand-Target Pair