Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50037053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117334 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc5ccccc5c4)cc3)c2cc1OCCOC Show InChI InChI=1S/C35H37N5O6/c1-42-17-19-44-32-22-30-31(23-33(32)45-20-18-43-2)36-24-37-34(30)39-13-15-40(16-14-39)35(41)38-27-8-11-28(12-9-27)46-29-10-7-25-5-3-4-6-26(25)21-29/h3-12,21-24H,13-20H2,1-2H3,(H,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117342 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4cccc5cnccc45)cc3)c2cc1OCCOC Show InChI InChI=1S/C34H36N6O6/c1-42-16-18-44-31-20-28-29(21-32(31)45-19-17-43-2)36-23-37-33(28)39-12-14-40(15-13-39)34(41)38-25-6-8-26(9-7-25)46-30-5-3-4-24-22-35-11-10-27(24)30/h3-11,20-23H,12-19H2,1-2H3,(H,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117354 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4cccc5[nH]ccc45)cc3)c2cc1OCCOC Show InChI InChI=1S/C33H36N6O6/c1-41-16-18-43-30-20-26-28(21-31(30)44-19-17-42-2)35-22-36-32(26)38-12-14-39(15-13-38)33(40)37-23-6-8-24(9-7-23)45-29-5-3-4-27-25(29)10-11-34-27/h3-11,20-22,34H,12-19H2,1-2H3,(H,37,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117330 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C(C)(C)C)c2cc1OCCOC Show InChI InChI=1S/C29H39N5O5/c1-29(2,3)21-6-8-22(9-7-21)32-28(35)34-12-10-33(11-13-34)27-23-18-25(38-16-14-36-4)26(39-17-15-37-5)19-24(23)30-20-31-27/h6-9,18-20H,10-17H2,1-5H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117348 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4cccc5ncccc45)cc3)c2cc1OCCOC Show InChI InChI=1S/C34H36N6O6/c1-42-17-19-44-31-21-27-29(22-32(31)45-20-18-43-2)36-23-37-33(27)39-13-15-40(16-14-39)34(41)38-24-8-10-25(11-9-24)46-30-7-3-6-28-26(30)5-4-12-35-28/h3-12,21-23H,13-20H2,1-2H3,(H,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117378 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc5[nH]ccc5c4)cc3)c2cc1OC Show InChI InChI=1S/C31H32N6O5/c1-39-15-16-41-29-19-27-25(18-28(29)40-2)30(34-20-33-27)36-11-13-37(14-12-36)31(38)35-22-3-5-23(6-4-22)42-24-7-8-26-21(17-24)9-10-32-26/h3-10,17-20,32H,11-16H2,1-2H3,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117323 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OCCOC Show InChI InChI=1S/C31H35N5O6/c1-38-16-18-40-28-20-26-27(21-29(28)41-19-17-39-2)32-22-33-30(26)35-12-14-36(15-13-35)31(37)34-23-8-10-25(11-9-23)42-24-6-4-3-5-7-24/h3-11,20-22H,12-19H2,1-2H3,(H,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117316 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(cc4)C(C)(C)C)cc3)c2cc1OCCOC Show InChI InChI=1S/C35H43N5O6/c1-35(2,3)25-6-10-27(11-7-25)46-28-12-8-26(9-13-28)38-34(41)40-16-14-39(15-17-40)33-29-22-31(44-20-18-42-4)32(45-21-19-43-5)23-30(29)36-24-37-33/h6-13,22-24H,14-21H2,1-5H3,(H,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117356 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4cccc5NCCc45)cc3)c2cc1OCCOC Show InChI InChI=1S/C33H38N6O6/c1-41-16-18-43-30-20-26-28(21-31(30)44-19-17-42-2)35-22-36-32(26)38-12-14-39(15-13-38)33(40)37-23-6-8-24(9-7-23)45-29-5-3-4-27-25(29)10-11-34-27/h3-9,20-22,34H,10-19H2,1-2H3,(H,37,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM13535 (4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117328 (4-{7-[3-(3,3-Difluoro-piperidin-1-yl)-propoxy]-6-m...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCC(F)(F)C1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H40F2N6O4/c1-22(2)43-24-8-6-23(7-9-24)36-30(40)39-15-13-38(14-16-39)29-25-18-27(41-3)28(19-26(25)34-21-35-29)42-17-5-12-37-11-4-10-31(32,33)20-37/h6-9,18-19,21-22H,4-5,10-17,20H2,1-3H3,(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117377 (4-{7-[3-(4,4-Difluoro-piperidin-1-yl)-propoxy]-6-m...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCC(F)(F)CC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H40F2N6O4/c1-22(2)43-24-7-5-23(6-8-24)36-30(40)39-16-14-38(15-17-39)29-25-19-27(41-3)28(20-26(25)34-21-35-29)42-18-4-11-37-12-9-31(32,33)10-13-37/h5-8,19-22H,4,9-18H2,1-3H3,(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117360 (4-[7-(2-Methoxy-ethoxy)-quinazolin-4-yl]-piperazin...) Show SMILES COCCOc1ccc2c(ncnc2c1)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H29N5O4/c1-35-17-18-36-24-11-12-25-26(19-24)29-20-30-27(25)32-13-15-33(16-14-32)28(34)31-21-7-9-23(10-8-21)37-22-5-3-2-4-6-22/h2-12,19-20H,13-18H2,1H3,(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117352 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H31N5O5/c1-36-16-17-38-27-19-25-24(18-26(27)37-2)28(31-20-30-25)33-12-14-34(15-13-33)29(35)32-21-8-10-23(11-9-21)39-22-6-4-3-5-7-22/h3-11,18-20H,12-17H2,1-2H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117304 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OCCOC Show InChI InChI=1S/C28H37N5O6/c1-20(2)39-22-7-5-21(6-8-22)31-28(34)33-11-9-32(10-12-33)27-23-17-25(37-15-13-35-3)26(38-16-14-36-4)18-24(23)29-19-30-27/h5-8,17-20H,9-16H2,1-4H3,(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117333 (4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C29H35N7O3/c1-38-26-18-24-25(19-27(26)39-17-5-12-34-10-3-2-4-11-34)31-21-32-28(24)35-13-15-36(16-14-35)29(37)33-23-8-6-22(20-30)7-9-23/h6-9,18-19,21H,2-5,10-17H2,1H3,(H,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117365 (4-[6-Methoxy-7-(3-pyrrolidin-1-yl-propoxy)-quinazo...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C30H40N6O4/c1-22(2)40-24-9-7-23(8-10-24)33-30(37)36-16-14-35(15-17-36)29-25-19-27(38-3)28(20-26(25)31-21-32-29)39-18-6-13-34-11-4-5-12-34/h7-10,19-22H,4-6,11-18H2,1-3H3,(H,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117313 (4-[6-(2-Methoxy-ethoxy)-7-(2-piperidin-1-yl-ethoxy...) Show SMILES COCCOc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C30H37N7O4/c1-39-17-18-41-27-19-25-26(20-28(27)40-16-15-35-9-3-2-4-10-35)32-22-33-29(25)36-11-13-37(14-12-36)30(38)34-24-7-5-23(21-31)6-8-24/h5-8,19-20,22H,2-4,9-18H2,1H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117375 (4-{6-Methoxy-7-[3-(propane-1-sulfonyl)-propoxy]-qu...) Show SMILES CCCS(=O)(=O)CCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OC Show InChI InChI=1S/C29H39N5O6S/c1-5-16-41(36,37)17-6-15-39-27-19-25-24(18-26(27)38-4)28(31-20-30-25)33-11-13-34(14-12-33)29(35)32-22-7-9-23(10-8-22)40-21(2)3/h7-10,18-21H,5-6,11-17H2,1-4H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117321 (4-{7-[3-(4,4-Difluoro-piperidin-1-yl)-propoxy]-6-m...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCC(F)(F)CC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C29H33F2N7O3/c1-40-25-17-23-24(18-26(25)41-16-2-9-36-10-7-29(30,31)8-11-36)33-20-34-27(23)37-12-14-38(15-13-37)28(39)35-22-5-3-21(19-32)4-6-22/h3-6,17-18,20H,2,7-16H2,1H3,(H,35,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117305 (4-[6-(2-Methoxy-ethoxy)-7-(2-pyrrolidin-1-yl-ethox...) Show SMILES COCCOc1cc2c(ncnc2cc1OCCN1CCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H42N6O5/c1-23(2)42-25-8-6-24(7-9-25)34-31(38)37-14-12-36(13-15-37)30-26-20-28(41-19-18-39-3)29(21-27(26)32-22-33-30)40-17-16-35-10-4-5-11-35/h6-9,20-23H,4-5,10-19H2,1-3H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117307 (4-[6-Methoxy-7-(2-pyrrolidin-1-yl-ethoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C27H31N7O3/c1-36-24-16-22-23(17-25(24)37-15-14-32-8-2-3-9-32)29-19-30-26(22)33-10-12-34(13-11-33)27(35)31-21-6-4-20(18-28)5-7-21/h4-7,16-17,19H,2-3,8-15H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117325 (4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1OCCOC Show InChI InChI=1S/C26H30N6O5/c1-34-11-13-36-23-15-21-22(16-24(23)37-14-12-35-2)28-18-29-25(21)31-7-9-32(10-8-31)26(33)30-20-5-3-19(17-27)4-6-20/h3-6,15-16,18H,7-14H2,1-2H3,(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117308 (4-[6-(2-Methoxy-ethoxy)-7-(2-pyrrolidin-1-yl-ethox...) Show SMILES COCCOc1cc2c(ncnc2cc1OCCN1CCCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C29H35N7O4/c1-38-16-17-40-26-18-24-25(19-27(26)39-15-14-34-8-2-3-9-34)31-21-32-28(24)35-10-12-36(13-11-35)29(37)33-23-6-4-22(20-30)5-7-23/h4-7,18-19,21H,2-3,8-17H2,1H3,(H,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117364 (4-[6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCOCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C29H38N6O5/c1-21(2)40-23-6-4-22(5-7-23)32-29(36)35-10-8-34(9-11-35)28-24-18-26(37-3)27(19-25(24)30-20-31-28)39-17-14-33-12-15-38-16-13-33/h4-7,18-21H,8-17H2,1-3H3,(H,32,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117318 (4-{7-[2-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-ethox...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCC2(CC1)OCCO2)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C30H35N7O5/c1-39-26-18-24-25(19-27(26)40-15-14-35-8-6-30(7-9-35)41-16-17-42-30)32-21-33-28(24)36-10-12-37(13-11-36)29(38)34-23-4-2-22(20-31)3-5-23/h2-5,18-19,21H,6-17H2,1H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117349 (4-[7-(3-Ethanesulfonyl-propoxy)-6-methoxy-quinazol...) Show SMILES CCS(=O)(=O)CCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OC Show InChI InChI=1S/C28H37N5O6S/c1-5-40(35,36)16-6-15-38-26-18-24-23(17-25(26)37-4)27(30-19-29-24)32-11-13-33(14-12-32)28(34)31-21-7-9-22(10-8-21)39-20(2)3/h7-10,17-20H,5-6,11-16H2,1-4H3,(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	409	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117343 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OC Show InChI InChI=1S/C26H33N5O5/c1-18(2)36-20-7-5-19(6-8-20)29-26(32)31-11-9-30(10-12-31)25-21-15-23(34-4)24(35-14-13-33-3)16-22(21)27-17-28-25/h5-8,15-18H,9-14H2,1-4H3,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117310 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C28H33N7O3/c1-37-25-17-23-24(18-26(25)38-16-15-33-9-3-2-4-10-33)30-20-31-27(23)34-11-13-35(14-12-34)28(36)32-22-7-5-21(19-29)6-8-22/h5-8,17-18,20H,2-4,9-16H2,1H3,(H,32,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117327 (4-[6-Methoxy-7-(2-thiomorpholin-4-yl-ethoxy)-quina...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCSCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C27H31N7O3S/c1-36-24-16-22-23(17-25(24)37-13-10-32-11-14-38-15-12-32)29-19-30-26(22)33-6-8-34(9-7-33)27(35)31-21-4-2-20(18-28)3-5-21/h2-5,16-17,19H,6-15H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117363 (4-[7-(2-Methoxy-ethoxy)-6-(2-piperidin-1-yl-ethoxy...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1OCCN1CCCCC1 Show InChI InChI=1S/C30H37N7O4/c1-39-17-18-41-28-20-26-25(19-27(28)40-16-15-35-9-3-2-4-10-35)29(33-22-32-26)36-11-13-37(14-12-36)30(38)34-24-7-5-23(21-31)6-8-24/h5-8,19-20,22H,2-4,9-18H2,1H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117366 (4-[6-Methoxy-7-(2-tetrazol-1-yl-ethoxy)-quinazolin...) Show SMILES COc1cc2c(ncnc2cc1OCCn1cnnn1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C26H31N9O4/c1-18(2)39-20-6-4-19(5-7-20)30-26(36)34-10-8-33(9-11-34)25-21-14-23(37-3)24(15-22(21)27-16-28-25)38-13-12-35-17-29-31-32-35/h4-7,14-18H,8-13H2,1-3H3,(H,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	507	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117357 (4-[6-Methoxy-7-(2-[1,2,3]triazol-2-yl-ethoxy)-quin...) Show SMILES COc1cc2c(ncnc2cc1OCCn1nccn1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C27H32N8O4/c1-19(2)39-21-6-4-20(5-7-21)32-27(36)34-12-10-33(11-13-34)26-22-16-24(37-3)25(17-23(22)28-18-29-26)38-15-14-35-30-8-9-31-35/h4-9,16-19H,10-15H2,1-3H3,(H,32,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	526	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117306 (4-[6-Methoxy-7-(2-pyrrol-1-yl-ethoxy)-quinazolin-4...) Show SMILES COc1cc2c(ncnc2cc1OCCn1cccc1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C27H27N7O3/c1-36-24-16-22-23(17-25(24)37-15-14-32-8-2-3-9-32)29-19-30-26(22)33-10-12-34(13-11-33)27(35)31-21-6-4-20(18-28)5-7-21/h2-9,16-17,19H,10-15H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117340 (4-[7-(3-Cyclohexyl-propoxy)-6-methoxy-quinazolin-4...) Show SMILES COc1cc2c(ncnc2cc1OCCCC1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C32H43N5O4/c1-23(2)41-26-13-11-25(12-14-26)35-32(38)37-17-15-36(16-18-37)31-27-20-29(39-3)30(21-28(27)33-22-34-31)40-19-7-10-24-8-5-4-6-9-24/h11-14,20-24H,4-10,15-19H2,1-3H3,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	813	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117344 (4-[6-Methoxy-7-(3-[1,2,3]triazol-2-yl-propoxy)-qui...) Show SMILES COc1cc2c(ncnc2cc1OCCCn1nccn1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C26H27N9O3/c1-37-23-15-21-22(16-24(23)38-14-2-9-35-30-7-8-31-35)28-18-29-25(21)33-10-12-34(13-11-33)26(36)32-20-5-3-19(17-27)4-6-20/h3-8,15-16,18H,2,9-14H2,1H3,(H,32,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	943	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117379 (4-[7-(2-Methoxy-ethoxy)-6-(2-morpholin-4-yl-ethoxy...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1OCCN1CCOCC1 Show InChI InChI=1S/C29H35N7O5/c1-38-16-17-41-27-19-25-24(18-26(27)40-15-12-34-10-13-39-14-11-34)28(32-21-31-25)35-6-8-36(9-7-35)29(37)33-23-4-2-22(20-30)3-5-23/h2-5,18-19,21H,6-17H2,1H3,(H,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117355 (4-[7-(2-Methoxy-ethoxy)-quinazolin-4-yl]-piperazin...) Show SMILES COCCOc1ccc2c(ncnc2c1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C23H24N6O3/c1-31-12-13-32-19-6-7-20-21(14-19)25-16-26-22(20)28-8-10-29(11-9-28)23(30)27-18-4-2-17(15-24)3-5-18/h2-7,14,16H,8-13H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117371 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)C#N)c2cc1OC Show InChI InChI=1S/C24H26N6O4/c1-32-11-12-34-22-14-20-19(13-21(22)33-2)23(27-16-26-20)29-7-9-30(10-8-29)24(31)28-18-5-3-17(15-25)4-6-18/h3-6,13-14,16H,7-12H2,1-2H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117324 (4-[6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCOCC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C27H31N7O4/c1-36-24-16-22-23(17-25(24)38-15-12-32-10-13-37-14-11-32)29-19-30-26(22)33-6-8-34(9-7-33)27(35)31-21-4-2-20(18-28)3-5-21/h2-5,16-17,19H,6-15H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117358 (4-{7-[2-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCS(=O)(=O)CC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C27H31N7O5S/c1-38-24-16-22-23(17-25(24)39-13-10-32-11-14-40(36,37)15-12-32)29-19-30-26(22)33-6-8-34(9-7-33)27(35)31-21-4-2-20(18-28)3-5-21/h2-5,16-17,19H,6-15H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117359 (4-[6-Methoxy-7-(2-[1,2,3]triazol-1-yl-ethoxy)-quin...) Show SMILES COc1cc2c(ncnc2cc1OCCn1ccnn1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C25H25N9O3/c1-36-22-14-20-21(15-23(22)37-13-12-34-7-6-29-31-34)27-17-28-24(20)32-8-10-33(11-9-32)25(35)30-19-4-2-18(16-26)3-5-19/h2-7,14-15,17H,8-13H2,1H3,(H,30,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117369 (4-[6-Methoxy-7-(3-[1,2,3]triazol-1-yl-propoxy)-qui...) Show SMILES COc1cc2c(ncnc2cc1OCCCn1ccnn1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C26H27N9O3/c1-37-23-15-21-22(16-24(23)38-14-2-8-35-9-7-30-32-35)28-18-29-25(21)33-10-12-34(13-11-33)26(36)31-20-5-3-19(17-27)4-6-20/h3-7,9,15-16,18H,2,8,10-14H2,1H3,(H,31,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117350 (4-[7-(2-Methoxy-ethoxy)-6-(2-morpholin-4-yl-ethoxy...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OCCN1CCOCC1 Show InChI InChI=1S/C31H42N6O6/c1-23(2)43-25-6-4-24(5-7-25)34-31(38)37-10-8-36(9-11-37)30-26-20-28(41-17-14-35-12-15-40-16-13-35)29(42-19-18-39-3)21-27(26)32-22-33-30/h4-7,20-23H,8-19H2,1-3H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117347 (4-[7-(3-Hydroxy-propoxy)-6-methoxy-quinazolin-4-yl...) Show SMILES COc1cc2c(ncnc2cc1OCCCO)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C26H33N5O5/c1-18(2)36-20-7-5-19(6-8-20)29-26(33)31-11-9-30(10-12-31)25-21-15-23(34-3)24(35-14-4-13-32)16-22(21)27-17-28-25/h5-8,15-18,32H,4,9-14H2,1-3H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117372 (4-{7-[2-(4-Hydroxy-piperidin-1-yl)-ethoxy]-6-metho...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCC(O)CC1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C28H33N7O4/c1-38-25-16-23-24(17-26(25)39-15-14-33-8-6-22(36)7-9-33)30-19-31-27(23)34-10-12-35(13-11-34)28(37)32-21-4-2-20(18-29)3-5-21/h2-5,16-17,19,22,36H,6-15H2,1H3,(H,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117339 (4-[7-(2-Imidazol-1-yl-ethoxy)-6-methoxy-quinazolin...) Show SMILES COc1cc2c(ncnc2cc1OCCn1ccnc1)N1CCN(CC1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C26H26N8O3/c1-36-23-14-21-22(15-24(23)37-13-12-32-7-6-28-18-32)29-17-30-25(21)33-8-10-34(11-9-33)26(35)31-20-4-2-19(16-27)3-5-20/h2-7,14-15,17-18H,8-13H2,1H3,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117373 (4-{6-Methoxy-7-[3-(1-methyl-4,5-dihydro-1H-imidazo...) Show SMILES COc1cc2c(ncnc2cc1OCCCC1=NCCN1C)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 |t:18| Show InChI InChI=1S/C30H39N7O4/c1-21(2)41-23-9-7-22(8-10-23)34-30(38)37-15-13-36(14-16-37)29-24-18-26(39-4)27(19-25(24)32-20-33-29)40-17-5-6-28-31-11-12-35(28)3/h7-10,18-21H,5-6,11-17H2,1-4H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair