Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425166 (CHEMBL2313573) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425170 (CHEMBL2313569) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425148 (CHEMBL2313566) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425151 (CHEMBL2313563) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425157 (CHEMBL2313272) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425168 (CHEMBL2313571) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425164 (CHEMBL2313265) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425163 (CHEMBL2313266) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425149 (CHEMBL2313565) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425167 (CHEMBL2313572) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425153 (CHEMBL2313561) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425171 (CHEMBL2313568) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425152 (CHEMBL2313562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425160 (CHEMBL2313269) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425169 (CHEMBL2313570) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425165 (CHEMBL2313264) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425147 (CHEMBL2313567) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425154 (CHEMBL2313560) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Mus musculus) | BDBM50425150 (CHEMBL2313564) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development, LLC Curated by ChEMBL | Assay Description Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc... | Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1 | |||||||||||
More data for this Ligand-Target Pair |