Found 17 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50046835 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
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Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133749
(CHEMBL1412565)Show InChI InChI=1S/C13H12N4OS/c18-12(10-6-8-14-9-7-10)16-17-13(19)15-11-4-2-1-3-5-11/h1-9H,(H,16,18)(H2,15,17,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 317 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133803
(CHEMBL3633783)Show InChI InChI=1S/C11H13N3O2S/c1-2-7-12-11(17)14-13-10(16)8-5-3-4-6-9(8)15/h2-6,15H,1,7H2,(H,13,16)(H2,12,14,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133807
(CHEMBL3633779)Show InChI InChI=1S/C10H13N3O2S/c1-2-11-10(16)13-12-9(15)7-5-3-4-6-8(7)14/h3-6,14H,2H2,1H3,(H,12,15)(H2,11,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 878 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133787
(CHEMBL1442294)Show InChI InChI=1S/C9H12N4OS/c1-2-11-9(15)13-12-8(14)7-3-5-10-6-4-7/h3-6H,2H2,1H3,(H,12,14)(H2,11,13,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 884 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133862
(CHEMBL3633777)Show InChI InChI=1S/C14H14N4OS/c19-13(12-6-8-15-9-7-12)17-18-14(20)16-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,17,19)(H2,16,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 964 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133861
(CHEMBL1479002)Show InChI InChI=1S/C10H12N4OS/c1-2-5-12-10(16)14-13-9(15)8-3-6-11-7-4-8/h2-4,6-7H,1,5H2,(H,13,15)(H2,12,14,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133802
(CHEMBL3633776)Show InChI InChI=1S/C7H8N4OS/c8-7(13)11-10-6(12)5-1-3-9-4-2-5/h1-4H,(H,10,12)(H3,8,11,13) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 973 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133804
(CHEMBL3633782)Show InChI InChI=1S/C15H15N3O2S/c19-13-9-5-4-8-12(13)14(20)17-18-15(21)16-10-11-6-2-1-3-7-11/h1-9,19H,10H2,(H,17,20)(H2,16,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133860
(CHEMBL3633778)Show InChI InChI=1S/C8H9N3O2S/c9-8(14)11-10-7(13)5-3-1-2-4-6(5)12/h1-4,12H,(H,10,13)(H3,9,11,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133863
(CHEMBL3127420)Show InChI InChI=1S/C14H14N4OS/c1-10-2-4-12(5-3-10)16-14(20)18-17-13(19)11-6-8-15-9-7-11/h2-9H,1H3,(H,17,19)(H2,16,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133806
(CHEMBL3633780)Show InChI InChI=1S/C14H13N3O2S/c18-12-9-5-4-8-11(12)13(19)16-17-14(20)15-10-6-2-1-3-7-10/h1-9,18H,(H,16,19)(H2,15,17,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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Similars
| Article PubMed
| 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50133805
(CHEMBL3633781)Show InChI InChI=1S/C15H15N3O2S/c1-10-6-8-11(9-7-10)16-15(21)18-17-14(20)12-4-2-3-5-13(12)19/h2-9,19H,1H3,(H,17,20)(H2,16,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM26187
(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)Show InChI InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM26197
(CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco |...)Show InChI InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
| Article PubMed
| 7.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM26193
(2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHE...)Show InChI InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| 7.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Balikesir University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 25: 5636-41 (2015)
Article DOI: 10.1016/j.bmcl.2015.10.021 BindingDB Entry DOI: 10.7270/Q251412B |
More data for this Ligand-Target Pair | |