Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-(apurinic or apyrimidinic site) endonuclease (Homo sapiens (Human)) | BDBM119124 ((E)-2-[(4,5-Dimethoxy-2-methyl-3,6-dioxocyclohexa-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Indiana University School of Medicine, Indianapolis, IN 46202, USA | Assay Description E3330 or E3330-amide was preincubated with 2 μL of APE1 (reduced with 1.0 mM DTT for 10 min and then diluted to a concentration of 0.06 mM with ... | Biochemistry 52: 2955-66 (2013) Article DOI: 10.1021/bi400179m BindingDB Entry DOI: 10.7270/Q2TQ605T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-(apurinic or apyrimidinic site) endonuclease (Homo sapiens (Human)) | BDBM50303955 ((E)-3-(5,6-Dimethoxy-3-methyl-14-dioxocyclohexa-25...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Indiana University School of Medicine, Indianapolis, IN 46202, USA | Assay Description E3330 or E3330-amide was preincubated with 2 μL of APE1 (reduced with 1.0 mM DTT for 10 min and then diluted to a concentration of 0.06 mM with ... | Biochemistry 52: 2955-66 (2013) Article DOI: 10.1021/bi400179m BindingDB Entry DOI: 10.7270/Q2TQ605T | |||||||||||
More data for this Ligand-Target Pair |