BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6856
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM154576 (K03861 (1)) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	7.5	834.45
University of Oxford					Assay Description All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 �C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...				ACS Chem Biol 10: 2116-25 (2015) Article DOI: 10.1021/acschembio.5b00398 BindingDB Entry DOI: 10.7270/Q2VH5MKH
University of Oxford					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 [C118L,A144C] (Homo sapiens (Human))	BDBM154576 (K03861 (1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.70	n/a	n/a	n/a	7.5	834.45
University of Oxford					Assay Description All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 �C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...				ACS Chem Biol 10: 2116-25 (2015) Article DOI: 10.1021/acschembio.5b00398 BindingDB Entry DOI: 10.7270/Q2VH5MKH
University of Oxford					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 [A144C] (Homo sapiens (Human))	BDBM154576 (K03861 (1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	15.4	n/a	n/a	n/a	7.5	834.45
University of Oxford					Assay Description All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 �C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...				ACS Chem Biol 10: 2116-25 (2015) Article DOI: 10.1021/acschembio.5b00398 BindingDB Entry DOI: 10.7270/Q2VH5MKH
University of Oxford					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 [C118L] (Homo sapiens (Human))	BDBM154576 (K03861 (1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	18.6	n/a	n/a	n/a	7.5	834.45
University of Oxford					Assay Description All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 �C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...				ACS Chem Biol 10: 2116-25 (2015) Article DOI: 10.1021/acschembio.5b00398 BindingDB Entry DOI: 10.7270/Q2VH5MKH
University of Oxford					More data for this Ligand-Target Pair