Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM155343 (US9006249, Example 49-2 | US9603819, Example 49-2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153121 (US8993631, 29-2 | US9006249, Example 49-1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM155344 (US9006249, Example 49-3 | US9603819, Example 49-3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153108 (US8993631, 16-5 | US9006249, Example 3-32 | US9603...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153109 (US8993631, 16-8 | US9006249, Example 3-60) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM155342 (US9006249, Example 13-1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153116 (US8993631, 19 | US9006249, Example 7-1 | US9603819...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 93 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153117 (US8993631, 20 | US9006249, Example 9-1 | US9603819...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 142 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153107 (US8993631, 16-3 | US9006249, Example 3-6 | US96038...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153113 (US8993631, 15-1 | US9006249, Example 2-1 | US96038...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 267 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153112 (US8993631, 14-1 | US9006249, Example 1-1 | US96038...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 283 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153114 (US8993631, 17 | US9006249, Example 5-1 | US9603819...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM153115 (US8993631, 18-1 | US9006249, Example 6-1 | US96038...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ... | US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R | |||||||||||
More data for this Ligand-Target Pair |