BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 7502
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198173 (2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198172 (2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198171 (2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198174 (2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198176 (2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198175 (2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198174 (2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198171 (2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198175 (2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198173 (2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198176 (2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198172 (2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair