Compile Data Set for Download or QSAR

Found 565 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 7775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217130 (US9302989, 451) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)N1Cc2ccc(cc2C1)C#N Show InChI InChI=1S/C26H30N4O2/c27-17-21-9-10-23-18-30(19-24(23)16-21)26(32)28-13-5-4-6-20-11-14-29(15-12-20)25(31)22-7-2-1-3-8-22/h1-3,7-10,16,20H,4-6,11-15,18-19H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.946	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217112 (US9302989, 407) Show SMILES O=C(Nc1ccc(cc1)C1CCN(CC1)C(=O)c1ccccc1)N1Cc2ccccc2C1 Show InChI InChI=1S/C27H27N3O2/c31-26(22-6-2-1-3-7-22)29-16-14-21(15-17-29)20-10-12-25(13-11-20)28-27(32)30-18-23-8-4-5-9-24(23)19-30/h1-13,21H,14-19H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.45	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217153 (US9302989, 563) Show SMILES Brc1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C22H24BrN3O2/c23-18-6-5-16-13-26(14-17(16)12-18)22(28)25-20-9-7-19(8-10-20)24-21(27)11-15-3-1-2-4-15/h5-10,12,15H,1-4,11,13-14H2,(H,24,27)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.66	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216340 (US9302989, 285) Show SMILES COc1cc(CNC(=O)c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)cc(OC)c1 Show InChI InChI=1S/C24H24N4O4/c1-31-21-9-16(10-22(11-21)32-2)12-26-23(29)17-3-5-20(6-4-17)27-24(30)28-14-18-7-8-25-13-19(18)15-28/h3-11,13H,12,14-15H2,1-2H3,(H,26,29)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.92	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216548 (US9302989, 564) Show SMILES O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(cc3C2)C#N)cc1 Show InChI InChI=1S/C23H24N4O2/c24-13-17-5-6-18-14-27(15-19(18)11-17)23(29)26-21-9-7-20(8-10-21)25-22(28)12-16-3-1-2-4-16/h5-11,16H,1-4,12,14-15H2,(H,25,28)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.96	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217165 (US9302989, 582) Show SMILES COCCNC(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C26H32N4O4/c1-34-13-12-27-25(32)19-6-7-20-16-30(17-21(20)15-19)26(33)29-23-10-8-22(9-11-23)28-24(31)14-18-4-2-3-5-18/h6-11,15,18H,2-5,12-14,16-17H2,1H3,(H,27,32)(H,28,31)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.05	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216341 (US9302989, 286) Show SMILES Clc1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)cc1 Show InChI InChI=1S/C22H19ClN4O2/c23-19-5-1-15(2-6-19)11-25-21(28)16-3-7-20(8-4-16)26-22(29)27-13-17-9-10-24-12-18(17)14-27/h1-10,12H,11,13-14H2,(H,25,28)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.06	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217145 (US9302989, 543) Show SMILES CCCC(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 |c:8| Show InChI InChI=1S/C23H26N4O2/c1-2-3-22(28)26-12-9-18(10-13-26)17-4-6-21(7-5-17)25-23(29)27-15-19-8-11-24-14-20(19)16-27/h4-9,11,14H,2-3,10,12-13,15-16H2,1H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.13	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217057 (US9302989, 349) Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)N1Cc2ccccc2C1 Show InChI InChI=1S/C25H31N3O2/c29-24(21-9-2-1-3-10-21)27-16-13-20(14-17-27)8-6-7-15-26-25(30)28-18-22-11-4-5-12-23(22)19-28/h1-5,9-12,20H,6-8,13-19H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217163 (US9302989, 580) Show SMILES O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(cc3C2)-c2cccnc2)cc1 Show InChI InChI=1S/C27H28N4O2/c32-26(14-19-4-1-2-5-19)29-24-9-11-25(12-10-24)30-27(33)31-17-22-8-7-20(15-23(22)18-31)21-6-3-13-28-16-21/h3,6-13,15-16,19H,1-2,4-5,14,17-18H2,(H,29,32)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.39	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217144 (US9302989, 542) Show SMILES O=C(NCCCCc1ccccc1)N1Cc2ccc(cc2C1)C#N Show InChI InChI=1S/C20H21N3O/c21-13-17-9-10-18-14-23(15-19(18)12-17)20(24)22-11-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-10,12H,4-5,8,11,14-15H2,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.77	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217147 (US9302989, 545) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1ccccc1)N1Cc2ccncc2C1 |t:10| Show InChI InChI=1S/C26H24N4O2/c31-25(21-4-2-1-3-5-21)29-14-11-20(12-15-29)19-6-8-24(9-7-19)28-26(32)30-17-22-10-13-27-16-23(22)18-30/h1-11,13,16H,12,14-15,17-18H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.78	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215807 (US9302989, 2) Show SMILES NCc1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)cc1 Show InChI InChI=1S/C24H23FN4O2/c25-21-8-5-19-14-29(15-20(19)11-21)24(31)28-22-9-6-18(7-10-22)23(30)27-13-17-3-1-16(12-26)2-4-17/h1-11H,12-15,26H2,(H,27,30)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.78	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217166 (US9302989, 583) Show SMILES OCCNC(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C25H30N4O4/c30-12-11-26-24(32)18-5-6-19-15-29(16-20(19)14-18)25(33)28-22-9-7-21(8-10-22)27-23(31)13-17-3-1-2-4-17/h5-10,14,17,30H,1-4,11-13,15-16H2,(H,26,32)(H,27,31)(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	2.82	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217146 (US9302989, 544) Show SMILES CC(C)C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 |c:8| Show InChI InChI=1S/C23H26N4O2/c1-16(2)22(28)26-11-8-18(9-12-26)17-3-5-21(6-4-17)25-23(29)27-14-19-7-10-24-13-20(19)15-27/h3-8,10,13,16H,9,11-12,14-15H2,1-2H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.02	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215808 (US9302989, 3) Show SMILES O=C(Nc1ccc(cc1)C(=O)NCCCc1ccccc1)N1Cc2ccc(cc2C1)C#N Show InChI InChI=1S/C26H24N4O2/c27-16-20-8-9-22-17-30(18-23(22)15-20)26(32)29-24-12-10-21(11-13-24)25(31)28-14-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-13,15H,4,7,14,17-18H2,(H,28,31)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.09	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217162 (US9302989, 579) Show SMILES O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(cc3C2)-c2cc[nH]n2)cc1 Show InChI InChI=1S/C25H27N5O2/c31-24(13-17-3-1-2-4-17)27-21-7-9-22(10-8-21)28-25(32)30-15-19-6-5-18(14-20(19)16-30)23-11-12-26-29-23/h5-12,14,17H,1-4,13,15-16H2,(H,26,29)(H,27,31)(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.14	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217041 (US9302989, 333) Show SMILES CC(C)S(=O)(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:9| Show InChI InChI=1S/C23H27N3O3S/c1-17(2)30(28,29)26-13-11-19(12-14-26)18-7-9-22(10-8-18)24-23(27)25-15-20-5-3-4-6-21(20)16-25/h3-11,17H,12-16H2,1-2H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.15	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216593 (US9302989, 473) Show SMILES Fc1ccccc1C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:13| Show InChI InChI=1S/C27H24FN3O2/c28-25-8-4-3-7-24(25)26(32)30-15-13-20(14-16-30)19-9-11-23(12-10-19)29-27(33)31-17-21-5-1-2-6-22(21)18-31/h1-13H,14-18H2,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.21	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217134 (US9302989, 497) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NCc1ccc(CNC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H27FN4O3/c32-27-13-10-25-19-36(20-26(25)16-27)31(39)35-28-14-11-24(12-15-28)30(38)34-18-22-8-6-21(7-9-22)17-33-29(37)23-4-2-1-3-5-23/h1-16H,17-20H2,(H,33,37)(H,34,38)(H,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.31	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216658 (US9302989, 546) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)C1CCOC1)N1Cc2ccncc2C1 |t:10| Show InChI InChI=1S/C24H26N4O3/c29-23(20-8-12-31-16-20)27-10-6-18(7-11-27)17-1-3-22(4-2-17)26-24(30)28-14-19-5-9-25-13-21(19)15-28/h1-6,9,13,20H,7-8,10-12,14-16H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.32	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216588 (US9302989, 468) Show SMILES Cc1ccccc1C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:13| Show InChI InChI=1S/C28H27N3O2/c1-20-6-2-5-9-26(20)27(32)30-16-14-22(15-17-30)21-10-12-25(13-11-21)29-28(33)31-18-23-7-3-4-8-24(23)19-31/h2-14H,15-19H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.39	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216580 (US9302989, 459) Show SMILES CCC(C)C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:9| Show InChI InChI=1S/C25H29N3O2/c1-3-18(2)24(29)27-14-12-20(13-15-27)19-8-10-23(11-9-19)26-25(30)28-16-21-6-4-5-7-22(21)17-28/h4-12,18H,3,13-17H2,1-2H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.62	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215809 (US9302989, 4) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NCC1CCCC1 Show InChI InChI=1S/C22H24FN3O2/c23-19-8-5-17-13-26(14-18(17)11-19)22(28)25-20-9-6-16(7-10-20)21(27)24-12-15-3-1-2-4-15/h5-11,15H,1-4,12-14H2,(H,24,27)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.71	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217076 (US9302989, 368) Show SMILES O=C(Nc1ccc(cn1)C(=O)N1CCN(CC1)c1ccccn1)N1Cc2ccccc2C1 Show InChI InChI=1S/C24H24N6O2/c31-23(29-13-11-28(12-14-29)22-7-3-4-10-25-22)18-8-9-21(26-15-18)27-24(32)30-16-19-5-1-2-6-20(19)17-30/h1-10,15H,11-14,16-17H2,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.73	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216594 (US9302989, 474) Show SMILES Fc1cccc(c1)C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:13| Show InChI InChI=1S/C27H24FN3O2/c28-24-7-3-6-21(16-24)26(32)30-14-12-20(13-15-30)19-8-10-25(11-9-19)29-27(33)31-17-22-4-1-2-5-23(22)18-31/h1-12,16H,13-15,17-18H2,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.89	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217164 (US9302989, 581) Show SMILES Cn1cc(cn1)-c1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C26H29N5O2/c1-30-15-22(14-27-30)19-6-7-20-16-31(17-21(20)13-19)26(33)29-24-10-8-23(9-11-24)28-25(32)12-18-4-2-3-5-18/h6-11,13-15,18H,2-5,12,16-17H2,1H3,(H,28,32)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216356 (US9302989, 554) Show SMILES O=C(Nc1ccc(cc1)C(=O)NCC1CCCOC1)N1Cc2ccncc2C1 Show InChI InChI=1S/C21H24N4O3/c26-20(23-10-15-2-1-9-28-14-15)16-3-5-19(6-4-16)24-21(27)25-12-17-7-8-22-11-18(17)13-25/h3-8,11,15H,1-2,9-10,12-14H2,(H,23,26)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.01	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216093 (US9302989, 568) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NCC1CCCOC1 Show InChI InChI=1S/C22H24FN3O3/c23-19-6-3-17-12-26(13-18(17)10-19)22(28)25-20-7-4-16(5-8-20)21(27)24-11-15-2-1-9-29-14-15/h3-8,10,15H,1-2,9,11-14H2,(H,24,27)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.12	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217040 (US9302989, 332) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1ccccc1)N1Cc2ccccc2C1 |t:10| Show InChI InChI=1S/C27H25N3O2/c31-26(22-6-2-1-3-7-22)29-16-14-21(15-17-29)20-10-12-25(13-11-20)28-27(32)30-18-23-8-4-5-9-24(23)19-30/h1-14H,15-19H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215811 (US9302989, 6) Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCN(CC1)c1nccc2occc12)N1Cc2ccccc2C1 Show InChI InChI=1S/C27H25N5O3/c33-26(31-14-12-30(13-15-31)25-23-10-16-35-24(23)9-11-28-25)19-5-7-22(8-6-19)29-27(34)32-17-20-3-1-2-4-21(20)18-32/h1-11,16H,12-15,17-18H2,(H,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.25	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216342 (US9302989, 287) Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCN(CC1)c1ccccn1)N1Cc2ccncc2C1 Show InChI InChI=1S/C24H24N6O2/c31-23(29-13-11-28(12-14-29)22-3-1-2-9-26-22)18-4-6-21(7-5-18)27-24(32)30-16-19-8-10-25-15-20(19)17-30/h1-10,15H,11-14,16-17H2,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.35	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217160 (US9302989, 577) Show SMILES NC(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C23H26N4O3/c24-22(29)16-5-6-17-13-27(14-18(17)12-16)23(30)26-20-9-7-19(8-10-20)25-21(28)11-15-3-1-2-4-15/h5-10,12,15H,1-4,11,13-14H2,(H2,24,29)(H,25,28)(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.39	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216590 (US9302989, 470) Show SMILES COc1ccccc1C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:14| Show InChI InChI=1S/C28H27N3O3/c1-34-26-9-5-4-8-25(26)27(32)30-16-14-21(15-17-30)20-10-12-24(13-11-20)29-28(33)31-18-22-6-2-3-7-23(22)19-31/h2-14H,15-19H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.45	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216343 (US9302989, 288) Show SMILES O=C(Nc1ccc(cc1)C(=O)NCCCc1ccccc1)N1Cc2ccncc2C1 Show InChI InChI=1S/C24H24N4O2/c29-23(26-13-4-7-18-5-2-1-3-6-18)19-8-10-22(11-9-19)27-24(30)28-16-20-12-14-25-15-21(20)17-28/h1-3,5-6,8-12,14-15H,4,7,13,16-17H2,(H,26,29)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.47	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216609 (US9302989, 491) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1ccncn1)N1Cc2ccccc2C1 |t:10| Show InChI InChI=1S/C25H23N5O2/c31-24(23-9-12-26-17-27-23)29-13-10-19(11-14-29)18-5-7-22(8-6-18)28-25(32)30-15-20-3-1-2-4-21(20)16-30/h1-10,12,17H,11,13-16H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.55	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215812 (US9302989, 7) Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCN(CC1)c1ccccn1)N1Cc2ccc(cc2C1)C#N Show InChI InChI=1S/C26H24N6O2/c27-16-19-4-5-21-17-32(18-22(21)15-19)26(34)29-23-8-6-20(7-9-23)25(33)31-13-11-30(12-14-31)24-3-1-2-10-28-24/h1-10,15H,11-14,17-18H2,(H,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216604 (US9302989, 486) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1ccccn1)N1Cc2ccccc2C1 |t:10| Show InChI InChI=1S/C26H24N4O2/c31-25(24-7-3-4-14-27-24)29-15-12-20(13-16-29)19-8-10-23(11-9-19)28-26(32)30-17-21-5-1-2-6-22(21)18-30/h1-12,14H,13,15-18H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216602 (US9302989, 483) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1cscn1)N1Cc2ccccc2C1 |t:10| Show InChI InChI=1S/C24H22N4O2S/c29-23(22-15-31-16-25-22)27-11-9-18(10-12-27)17-5-7-21(8-6-17)26-24(30)28-13-19-3-1-2-4-20(19)14-28/h1-9,15-16H,10-14H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.79	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215813 (US9302989, 8) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NCc1ccccn1 Show InChI InChI=1S/C22H19FN4O2/c23-18-7-4-16-13-27(14-17(16)11-18)22(29)26-19-8-5-15(6-9-19)21(28)25-12-20-3-1-2-10-24-20/h1-11H,12-14H2,(H,25,28)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.88	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215814 (US9302989, 9) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H20FN3O2/c24-20-9-6-18-14-27(15-19(18)12-20)23(29)26-21-10-7-17(8-11-21)22(28)25-13-16-4-2-1-3-5-16/h1-12H,13-15H2,(H,25,28)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.02	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216601 (US9302989, 482) Show SMILES Cc1cc(C(=O)N2CCC(=CC2)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)c(C)[nH]1 |c:9| Show InChI InChI=1S/C27H28N4O2/c1-18-15-25(19(2)28-18)26(32)30-13-11-21(12-14-30)20-7-9-24(10-8-20)29-27(33)31-16-22-5-3-4-6-23(22)17-31/h3-11,15,28H,12-14,16-17H2,1-2H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.11	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216546 (US9302989, 311) Show SMILES O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccccc3C2)cc1 Show InChI InChI=1S/C22H25N3O2/c26-21(13-16-5-1-2-6-16)23-19-9-11-20(12-10-19)24-22(27)25-14-17-7-3-4-8-18(17)15-25/h3-4,7-12,16H,1-2,5-6,13-15H2,(H,23,26)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.24	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM215815 (US9302989, 10) Show SMILES COc1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc1OC Show InChI InChI=1S/C25H25N3O4/c1-31-22-12-7-17(13-23(22)32-2)14-26-24(29)18-8-10-21(11-9-18)27-25(30)28-15-19-5-3-4-6-20(19)16-28/h3-13H,14-16H2,1-2H3,(H,26,29)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217021 (US9302989, 313) Show SMILES COC(=O)c1ccc2CN(Cc2c1)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 Show InChI InChI=1S/C24H27N3O4/c1-31-23(29)17-6-7-18-14-27(15-19(18)13-17)24(30)26-21-10-8-20(9-11-21)25-22(28)12-16-4-2-3-5-16/h6-11,13,16H,2-5,12,14-15H2,1H3,(H,25,28)(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.41	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216603 (US9302989, 485) Show SMILES Cc1noc(C)c1C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:13| Show InChI InChI=1S/C26H26N4O3/c1-17-24(18(2)33-28-17)25(31)29-13-11-20(12-14-29)19-7-9-23(10-8-19)27-26(32)30-15-21-5-3-4-6-22(21)16-30/h3-11H,12-16H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.57	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216600 (US9302989, 480) Show SMILES O=C(Nc1ccc(cc1)C1=CCN(CC1)C(=O)c1ccsc1)N1Cc2ccccc2C1 |t:10| Show InChI InChI=1S/C25H23N3O2S/c29-24(22-11-14-31-17-22)27-12-9-19(10-13-27)18-5-7-23(8-6-18)26-25(30)28-15-20-3-1-2-4-21(20)16-28/h1-9,11,14,17H,10,12-13,15-16H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.71	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216086 (US9302989, 435) Show SMILES Fc1ccc2CN(Cc2c1)C(=O)Nc1ccc(cc1)C(=O)NC[C@@H]1CCCO1 Show InChI InChI=1S/C21H22FN3O3/c22-17-6-3-15-12-25(13-16(15)10-17)21(27)24-18-7-4-14(5-8-18)20(26)23-11-19-2-1-9-28-19/h3-8,10,19H,1-2,9,11-13H2,(H,23,26)(H,24,27)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.89	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM216589 (US9302989, 469) Show SMILES Cc1cccc(c1)C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:13| Show InChI InChI=1S/C28H27N3O2/c1-20-5-4-8-23(17-20)27(32)30-15-13-22(14-16-30)21-9-11-26(12-10-21)29-28(33)31-18-24-6-2-3-7-25(24)19-31/h2-13,17H,14-16,18-19H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.97	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM217039 (US9302989, 331) Show SMILES CC(C)C(=O)N1CCC(=CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 |c:8| Show InChI InChI=1S/C24H27N3O2/c1-17(2)23(28)26-13-11-19(12-14-26)18-7-9-22(10-8-18)25-24(29)27-15-20-5-3-4-6-21(20)16-27/h3-11,17H,12-16H2,1-2H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.11	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
					More data for this Ligand-Target Pair

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