Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with all data for assayid = 10 entry = 50026465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252353 (CHEMBL479413 | N-((S)-1-((S)-1-(3-bromo-4-(piperid...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N[C@H]1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C31H39BrN4O3S/c1-20(2)15-26(35-31(38)29-17-22-5-3-4-6-28(22)40-29)30(37)34-23-11-14-36(19-23)18-21-7-8-27(25(32)16-21)39-24-9-12-33-13-10-24/h3-8,16-17,20,23-24,26,33H,9-15,18-19H2,1-2H3,(H,34,37)(H,35,38)/t23-,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252147 (CHEMBL482259 | N-((S)-1-((R)-3-bromo-4-((R)-pyrrol...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(O[C@@H]3CCNC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C22H24BrCl2N3O2/c23-18-9-14(1-4-21(18)30-17-5-7-26-11-17)12-28-8-6-16(13-28)27-22(29)15-2-3-19(24)20(25)10-15/h1-4,9-10,16-17,26H,5-8,11-13H2,(H,27,29)/t16-,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252197 ((S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenethyl)p...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(CCc2ccc(OC3CCNCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C24H28BrCl2N3O2/c25-20-13-16(1-4-23(20)32-19-5-9-28-10-6-19)7-11-30-12-8-18(15-30)29-24(31)17-2-3-21(26)22(27)14-17/h1-4,13-14,18-19,28H,5-12,15H2,(H,29,31)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252355 (CHEMBL505360 | N-((S)-1-((S)-1-(3-bromo-4-(piperid...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N[C@H]1CCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 |r| Show InChI InChI=1S/C30H37BrN4O5S2/c1-19(2)15-25(34-30(37)28-16-20-5-3-4-6-27(20)41-28)29(36)33-21-11-14-35(18-21)42(38,39)23-7-8-26(24(31)17-23)40-22-9-12-32-13-10-22/h3-8,16-17,19,21-22,25,32H,9-15,18H2,1-2H3,(H,33,36)(H,34,37)/t21-,25-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252198 ((S)-N-(1-(3-chloro-4-(piperidin-4-yloxy)phenethyl)...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(CCc2ccc(OC3CCNCC3)c(Cl)c2)C1 |r| Show InChI InChI=1S/C24H28Cl3N3O2/c25-20-3-2-17(14-21(20)26)24(31)29-18-8-12-30(15-18)11-7-16-1-4-23(22(27)13-16)32-19-5-9-28-10-6-19/h1-4,13-14,18-19,28H,5-12,15H2,(H,29,31)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252354 (CHEMBL517991 | N-((S)-1-((S)-1-((R)-3-bromo-4-((R)...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N[C@H]1CCN(CCc2ccc(O[C@@H]3CCNC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C31H39BrN4O3S/c1-20(2)15-26(35-31(38)29-17-22-5-3-4-6-28(22)40-29)30(37)34-23-11-14-36(19-23)13-10-21-7-8-27(25(32)16-21)39-24-9-12-33-18-24/h3-8,16-17,20,23-24,26,33H,9-15,18-19H2,1-2H3,(H,34,37)(H,35,38)/t23-,24+,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252239 ((S)-N-(1-(3-methoxy-4-(piperidin-4-yloxy)phenethyl...) Show SMILES COc1cc(CCN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)ccc1OC1CCNCC1 |r| Show InChI InChI=1S/C25H31Cl2N3O3/c1-32-24-14-17(2-5-23(24)33-20-6-10-28-11-7-20)8-12-30-13-9-19(16-30)29-25(31)18-3-4-21(26)22(27)15-18/h2-5,14-15,19-20,28H,6-13,16H2,1H3,(H,29,31)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252096 ((+/-)-N-(1-(3-bromo-4-(1-methylpyrrolidin-3-yloxy)...) Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1Br Show InChI InChI=1S/C23H26BrCl2N3O2/c1-28-8-7-18(14-28)31-22-5-2-15(10-19(22)24)12-29-9-6-17(13-29)27-23(30)16-3-4-20(25)21(26)11-16/h2-5,10-11,17-18H,6-9,12-14H2,1H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252241 ((S)-N-(1-(4-(piperidin-4-yloxy)phenethyl)pyrrolidi...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(CCc2ccc(OC3CCNCC3)cc2)C1 |r| Show InChI InChI=1S/C24H29Cl2N3O2/c25-22-6-3-18(15-23(22)26)24(30)28-19-10-14-29(16-19)13-9-17-1-4-20(5-2-17)31-21-7-11-27-12-8-21/h1-6,15,19,21,27H,7-14,16H2,(H,28,30)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252148 (CHEMBL516606 | N-((S)-1-((S)-3-bromo-4-((S)-pyrrol...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(O[C@H]3CCNC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C22H24BrCl2N3O2/c23-18-9-14(1-4-21(18)30-17-5-7-26-11-17)12-28-8-6-16(13-28)27-22(29)15-2-3-19(24)20(25)10-15/h1-4,9-10,16-17,26H,5-8,11-13H2,(H,27,29)/t16-,17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252095 ((+/-)-N-(1-(3-chloro-4-(1-methylpyrrolidin-3-yloxy...) Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1Cl Show InChI InChI=1S/C23H26Cl3N3O2/c1-28-8-7-18(14-28)31-22-5-2-15(10-21(22)26)12-29-9-6-17(13-29)27-23(30)16-3-4-19(24)20(25)11-16/h2-5,10-11,17-18H,6-9,12-14H2,1H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252097 ((S)-N-(1-(3-bromo-4-(3-(dimethylamino)propoxy)benz...) Show SMILES CN(C)CCCOc1ccc(CN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1Br |r| Show InChI InChI=1S/C23H28BrCl2N3O2/c1-28(2)9-3-11-31-22-7-4-16(12-19(22)24)14-29-10-8-18(15-29)27-23(30)17-5-6-20(25)21(26)13-17/h4-7,12-13,18H,3,8-11,14-15H2,1-2H3,(H,27,30)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252199 ((S)-N-(1-(3-fluoro-4-(piperidin-4-yloxy)phenethyl)...) Show SMILES Fc1cc(CCN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)ccc1OC1CCNCC1 |r| Show InChI InChI=1S/C24H28Cl2FN3O2/c25-20-3-2-17(14-21(20)26)24(31)29-18-8-12-30(15-18)11-7-16-1-4-23(22(27)13-16)32-19-5-9-28-10-6-19/h1-4,13-14,18-19,28H,5-12,15H2,(H,29,31)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252240 ((S)-N-(1-(3-nitro-4-(piperidin-4-yloxy)phenethyl)p...) Show SMILES [O-][N+](=O)c1cc(CCN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)ccc1OC1CCNCC1 |r| Show InChI InChI=1S/C24H28Cl2N4O4/c25-20-3-2-17(14-21(20)26)24(31)28-18-8-12-29(15-18)11-7-16-1-4-23(22(13-16)30(32)33)34-19-5-9-27-10-6-19/h1-4,13-14,18-19,27H,5-12,15H2,(H,28,31)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252311 ((+/-)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsul...) Show SMILES Clc1ccc(cc1Cl)C(=O)NC1CCCCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 Show InChI InChI=1S/C24H28BrCl2N3O4S/c25-20-14-19(5-7-23(20)34-18-8-10-28-11-9-18)35(32,33)30-12-2-1-3-17(15-30)29-24(31)16-4-6-21(26)22(27)13-16/h4-7,13-14,17-18,28H,1-3,8-12,15H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252041 ((+/-)-N-(1-(4-(1-methylpyrrolidin-3-yloxy)benzyl)p...) Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C23H27Cl2N3O2/c1-27-10-9-20(15-27)30-19-5-2-16(3-6-19)13-28-11-8-18(14-28)26-23(29)17-4-7-21(24)22(25)12-17/h2-7,12,18,20H,8-11,13-15H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252042 ((+/-)-N-(1-(3-methyl-4-(1-methylpyrrolidin-3-yloxy...) Show SMILES CN1CCC(C1)Oc1ccc(CN2CCC(C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1C Show InChI InChI=1S/C24H29Cl2N3O2/c1-16-11-17(3-6-23(16)31-20-8-9-28(2)15-20)13-29-10-7-19(14-29)27-24(30)18-4-5-21(25)22(26)12-18/h3-6,11-12,19-20H,7-10,13-15H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50240962 (Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(R)-1-...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N[C@H]1CCN(Cc2ccc(OCCCN(C)C)cc2)C1 |r| Show InChI InChI=1S/C31H42N4O3S/c1-22(2)18-27(33-31(37)29-19-24-8-5-6-9-28(24)39-29)30(36)32-25-14-16-35(21-25)20-23-10-12-26(13-11-23)38-17-7-15-34(3)4/h5-6,8-13,19,22,25,27H,7,14-18,20-21H2,1-4H3,(H,32,36)(H,33,37)/t25-,27-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252242 ((S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfo...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 |r| Show InChI InChI=1S/C22H24BrCl2N3O4S/c23-18-12-17(2-4-21(18)32-16-5-8-26-9-6-16)33(30,31)28-10-7-15(13-28)27-22(29)14-1-3-19(24)20(25)11-14/h1-4,11-12,15-16,26H,5-10,13H2,(H,27,29)/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252312 (CHEMBL482302 | N-(1-(3-bromo-4-(piperidin-4-yloxy)...) Show SMILES Clc1ccc(cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 Show InChI InChI=1S/C23H26BrCl2N3O4S/c24-19-14-18(2-4-22(19)33-17-5-9-27-10-6-17)34(31,32)29-11-7-16(8-12-29)28-23(30)15-1-3-20(25)21(26)13-15/h1-4,13-14,16-17,27H,5-12H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50240963 ((S)-3,4-dichloro-N-(1-(4-(3-(dimethylamino)propoxy...) Show SMILES CN(C)CCCOc1ccc(CN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C23H29Cl2N3O2/c1-27(2)11-3-13-30-20-7-4-17(5-8-20)15-28-12-10-19(16-28)26-23(29)18-6-9-21(24)22(25)14-18/h4-9,14,19H,3,10-13,15-16H2,1-2H3,(H,26,29)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252196 ((S)-N-(1-(4-(1-benzylpiperidin-4-yloxy)-3-bromoben...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OC3CCN(Cc4ccccc4)CC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C30H32BrCl2N3O2/c31-26-16-22(19-36-13-10-24(20-36)34-30(37)23-7-8-27(32)28(33)17-23)6-9-29(26)38-25-11-14-35(15-12-25)18-21-4-2-1-3-5-21/h1-9,16-17,24-25H,10-15,18-20H2,(H,34,37)/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50240961 ((S)-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrro...) Show SMILES CN(C)CCCOc1ccc(CN2CC[C@@H](C2)NC(=O)c2ccc(Br)cc2)cc1 |r| Show InChI InChI=1S/C23H30BrN3O2/c1-26(2)13-3-15-29-22-10-4-18(5-11-22)16-27-14-12-21(17-27)25-23(28)19-6-8-20(24)9-7-19/h4-11,21H,3,12-17H2,1-2H3,(H,25,28)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50251944 ((R)-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrro...) Show SMILES CN(C)CCCOc1ccc(CN2CC[C@H](C2)NC(=O)c2ccc(Br)cc2)cc1 |r| Show InChI InChI=1S/C23H30BrN3O2/c1-26(2)13-3-15-29-22-10-4-18(5-11-22)16-27-14-12-21(17-27)25-23(28)19-6-8-20(24)9-7-19/h4-11,21H,3,12-17H2,1-2H3,(H,25,28)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252310 ((R)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfo...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@@H]1CCN(C1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1 |r| Show InChI InChI=1S/C22H24BrCl2N3O4S/c23-18-12-17(2-4-21(18)32-16-5-8-26-9-6-16)33(30,31)28-10-7-15(13-28)27-22(29)14-1-3-19(24)20(25)11-14/h1-4,11-12,15-16,26H,5-10,13H2,(H,27,29)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50251890 (CHEMBL481129 | N-(1-(4-(3-(dimethylamino)propoxy)b...) Show SMILES CN(C)CCCOc1ccc(CN2CCC(CC2)NC(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C24H31Cl2N3O2/c1-28(2)12-3-15-31-21-7-4-18(5-8-21)17-29-13-10-20(11-14-29)27-24(30)19-6-9-22(25)23(26)16-19/h4-9,16,20H,3,10-15,17H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252098 ((S)-N-(1-(3-bromo-4-(2-(pyrrolidin-1-yl)ethoxy)ben...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OCCN3CCCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C24H28BrCl2N3O2/c25-20-13-17(3-6-23(20)32-12-11-29-8-1-2-9-29)15-30-10-7-19(16-30)28-24(31)18-4-5-21(26)22(27)14-18/h3-6,13-14,19H,1-2,7-12,15-16H2,(H,28,31)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252146 ((S)-N-(1-(3-bromo-4-(2-(piperazin-1-yl)ethoxy)benz...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OCCN3CCNCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C24H29BrCl2N4O2/c25-20-13-17(1-4-23(20)33-12-11-30-9-6-28-7-10-30)15-31-8-5-19(16-31)29-24(32)18-2-3-21(26)22(27)14-18/h1-4,13-14,19,28H,5-12,15-16H2,(H,29,32)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252039 ((S)-N-(1-(3-(3-(dimethylamino)propoxy)benzyl)pyrro...) Show SMILES CN(C)CCCOc1cccc(CN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)c1 |r| Show InChI InChI=1S/C23H29Cl2N3O2/c1-27(2)10-4-12-30-20-6-3-5-17(13-20)15-28-11-9-19(16-28)26-23(29)18-7-8-21(24)22(25)14-18/h3,5-8,13-14,19H,4,9-12,15-16H2,1-2H3,(H,26,29)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252145 ((S)-N-(1-(3-bromo-4-(2-morpholinoethoxy)benzyl)pyr...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OCCN3CCOCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C24H28BrCl2N3O3/c25-20-13-17(1-4-23(20)33-12-9-29-7-10-32-11-8-29)15-30-6-5-19(16-30)28-24(31)18-2-3-21(26)22(27)14-18/h1-4,13-14,19H,5-12,15-16H2,(H,28,31)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50251892 (CHEMBL481130 | N-(3-((4-(3-(dimethylamino)propoxy)...) Show SMILES CN(C)CCCOc1ccc(CN(C)CCCNC(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C23H31Cl2N3O2/c1-27(2)13-5-15-30-20-9-6-18(7-10-20)17-28(3)14-4-12-26-23(29)19-8-11-21(24)22(25)16-19/h6-11,16H,4-5,12-15,17H2,1-3H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50251891 ((4-(4-(3-(dimethylamino)propoxy)benzyl)piperazin-1...) Show SMILES CN(C)CCCOc1ccc(CN2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C23H29Cl2N3O2/c1-26(2)10-3-15-30-20-7-4-18(5-8-20)17-27-11-13-28(14-12-27)23(29)19-6-9-21(24)22(25)16-19/h4-9,16H,3,10-15,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252040 ((S)-N-(1-(2-(3-(dimethylamino)propoxy)benzyl)pyrro...) Show SMILES CN(C)CCCOc1ccccc1CN1CC[C@@H](C1)NC(=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C23H29Cl2N3O2/c1-27(2)11-5-13-30-22-7-4-3-6-18(22)15-28-12-10-19(16-28)26-23(29)17-8-9-20(24)21(25)14-17/h3-4,6-9,14,19H,5,10-13,15-16H2,1-2H3,(H,26,29)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair