Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 12 (Homo sapiens (Human)) | BDBM50118225 (ARL 69931MX | Adenosine triphosphate derivative | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of ADP-induced aggregation preincubated for 5 mins followed by... | Bioorg Med Chem 23: 3880-906 (2015) Article DOI: 10.1016/j.bmc.2014.12.034 BindingDB Entry DOI: 10.7270/Q2MC91S4 | |||||||||||
More data for this Ligand-Target Pair |