Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276050 (2-[1-(3,4-dihydro-2H-chromen-4-ylmethyl)imidazol-4...) Show SMILES C(C1CCOc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276067 (2-[1-[(3-chloro-2-fluorophenyl)methyl]imidazol-4-y...) Show SMILES Fc1c(Cl)cccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C17H12ClFN6/c18-13-3-1-2-12(17(13)19)8-25-9-16(21-10-25)14-6-11(4-5-20-14)15-7-22-24-23-15/h1-7,9-10H,8H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276044 (2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]-4-(1H...) Show SMILES Clc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C18H15ClN6/c19-15-4-2-1-3-13(15)6-8-25-11-18(21-12-25)16-9-14(5-7-20-16)17-10-22-24-23-17/h1-5,7,9-12H,6,8H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276043 (2-[1-(1-phenylethyl)imidazol-4-yl]-4-(1H-triazol-4...) Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276045 (2-[1-[2-(2-methoxyphenyl)ethyl]imidazol-4-yl]-4-(1...) Show SMILES COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C19H18N6O/c1-26-19-5-3-2-4-14(19)7-9-25-12-18(21-13-25)16-10-15(6-8-20-16)17-11-22-24-23-17/h2-6,8,10-13H,7,9H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276046 (2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)imid...) Show SMILES C(C1CCCc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276047 (2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...) Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C20H20N6O/c1-2-27-20-6-4-3-5-15(20)8-10-26-13-19(22-14-26)17-11-16(7-9-21-17)18-12-23-25-24-18/h3-7,9,11-14H,2,8,10H2,1H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276048 (4-(1H-triazol-4-yl)-2-[1-[2-[2-(2,2,2-trifluoroeth...) Show SMILES FC(F)(F)COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C20H17F3N6O/c21-20(22,23)12-30-19-4-2-1-3-14(19)6-8-29-11-18(25-13-29)16-9-15(5-7-24-16)17-10-26-28-27-17/h1-5,7,9-11,13H,6,8,12H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276049 (2-[1-[2-[2-(cyclopropylmethoxy)phenyl]ethyl]imidaz...) Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCC1CC1 Show InChI InChI=1S/C22H22N6O/c1-2-4-22(29-14-16-5-6-16)17(3-1)8-10-28-13-21(24-15-28)19-11-18(7-9-23-19)20-12-25-27-26-20/h1-4,7,9,11-13,15-16H,5-6,8,10,14H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276041 (2-[5-(4-fluorophenyl)-1-methylimidazol-4-yl]-4-(1H...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C17H13FN6/c1-24-10-20-16(17(24)11-2-4-13(18)5-3-11)14-8-12(6-7-19-14)15-9-21-23-22-15/h2-10H,1H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276093 (2-(5-bromo-1-(2-chlorobenzyl)-1H-imidazol-4-yl)-4-...) Show SMILES Clc1ccccc1Cn1cnc(c1Br)-c1cc(ccn1)-c1cn[nH]n1 Show InChI InChI=1S/C17H12BrClN6/c18-17-16(14-7-11(5-6-20-14)15-8-22-24-23-15)21-10-25(17)9-12-3-1-2-4-13(12)19/h1-8,10H,9H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276039 (2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...) Show SMILES Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C11H10N6/c1-17-6-11(13-7-17)9-4-8(2-3-12-9)10-5-14-16-15-10/h2-7H,1H3,(H,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276040 (2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(1H-...) Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C17H13ClN6/c18-14-4-2-1-3-13(14)9-24-10-17(20-11-24)15-7-12(5-6-19-15)16-8-21-23-22-16/h1-8,10-11H,9H2,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276082 (1-benzyl-4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}...) Show SMILES C(c1ccccc1)n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C15H12N6/c1-2-4-11(5-3-1)8-21-9-15(17-10-21)12-6-13-14(7-16-12)19-20-18-13/h1-7,9-10H,8H2,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276073 (4-(5-fluoro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...) Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1 Show InChI InChI=1S/C22H17FN6/c23-22-21(26-28-27-22)17-8-10-24-19(12-17)20-13-29(14-25-20)11-9-16-6-3-5-15-4-1-2-7-18(15)16/h1-8,10,12-14H,9,11H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276072 (4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethoxy)p...) Show SMILES FC(F)(F)Oc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C19H15F3N6O/c20-19(21,22)29-18-4-2-1-3-13(18)6-8-28-11-17(24-12-28)15-9-14(5-7-23-15)16-10-25-27-26-16/h1-5,7,9-12H,6,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276070 (2-[1-[2-(2-chlorophenyl)-2-methylpropyl]imidazol-4...) Show SMILES CC(C)(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Cl Show InChI InChI=1S/C20H19ClN6/c1-20(2,15-5-3-4-6-16(15)21)12-27-11-19(23-13-27)17-9-14(7-8-22-17)18-10-24-26-25-18/h3-11,13H,12H2,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276069 (4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethyl)ph...) Show SMILES FC(F)(F)c1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C19H15F3N6/c20-19(21,22)15-4-2-1-3-13(15)6-8-28-11-18(24-12-28)16-9-14(5-7-23-16)17-10-25-27-26-17/h1-5,7,9-12H,6,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276068 (2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...) Show SMILES COc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F Show InChI InChI=1S/C18H15FN6O/c1-26-17-4-2-3-13(18(17)19)9-25-10-16(21-11-25)14-7-12(5-6-20-14)15-8-22-24-23-15/h2-8,10-11H,9H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276066 (2-[1-[(2-fluoro-3-methylphenyl)methyl]imidazol-4-y...) Show SMILES Cc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F Show InChI InChI=1S/C18H15FN6/c1-12-3-2-4-14(18(12)19)9-25-10-17(21-11-25)15-7-13(5-6-20-15)16-8-22-24-23-16/h2-8,10-11H,9H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276062 (2-[5-(4-fluoro-3-methoxyphenyl)-1-methylimidazol-4...) Show SMILES COc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C18H15FN6O/c1-25-10-21-17(18(25)12-3-4-13(19)16(8-12)26-2)14-7-11(5-6-20-14)15-9-22-24-23-15/h3-10H,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276061 (2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-(1H-...) Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1cccc2ccccc12 Show InChI InChI=1S/C22H18N6/c1-2-7-19-16(4-1)5-3-6-17(19)9-11-28-14-22(24-15-28)20-12-18(8-10-23-20)21-13-25-27-26-21/h1-8,10,12-15H,9,11H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276060 (2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...) Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl Show InChI InChI=1S/C18H12ClF3N6/c19-17-12(2-1-3-13(17)18(20,21)22)8-28-9-16(24-10-28)14-6-11(4-5-23-14)15-7-25-27-26-15/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276059 (2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...) Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl Show InChI InChI=1S/C17H12Cl2N6/c18-13-3-1-2-12(17(13)19)8-25-9-16(21-10-25)14-6-11(4-5-20-14)15-7-22-24-23-15/h1-7,9-10H,8H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276058 (2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...) Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2cccc(Cl)c2Cl)cn1 Show InChI InChI=1S/C17H11Cl2FN6/c18-12-3-1-2-11(15(12)19)7-26-8-14(22-9-26)13-6-10(4-5-21-13)16-17(20)24-25-23-16/h1-6,8-9H,7H2,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276057 (2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...) Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2I)c1Cl Show InChI InChI=1S/C17H11Cl2IN6/c18-12-3-1-2-11(15(12)19)7-26-8-14(22-9-26)13-6-10(4-5-21-13)16-17(20)24-25-23-16/h1-6,8-9H,7H2,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276054 (4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...) Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1 Show InChI InChI=1S/C23H17N7/c24-13-21-23(28-29-27-21)18-8-10-25-20(12-18)22-14-30(15-26-22)11-9-17-6-3-5-16-4-1-2-7-19(16)17/h1-8,10,12,14-15H,9,11H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276053 (4-[2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)i...) Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276042 (2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1c[nH]nn1 |(1.71,-3.53,;.22,-3.92,;-.68,-5.17,;-2.15,-4.69,;-2.15,-3.15,;-.68,-2.68,;-.29,-1.19,;-1.37,-.1,;-.98,1.39,;.51,1.78,;.91,3.27,;1.6,.7,;1.2,-.79,;2.29,-1.88,;3.78,-1.48,;4.87,-2.57,;5.27,-4.06,;6.36,-2.97,;-3.48,-2.38,;-3.48,-.84,;-4.82,-.07,;-6.15,-.84,;-6.15,-2.38,;-4.82,-3.15,;-4.82,1.47,;-6.06,2.37,;-5.59,3.84,;-4.05,3.84,;-3.57,2.37,)| Show InChI InChI=1S/C21H19FN6O/c1-28-12-24-20(17-8-14(6-7-23-17)18-10-25-27-26-18)21(28)16-5-4-15(22)9-19(16)29-11-13-2-3-13/h4-10,12-13H,2-3,11H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276051 (4-[2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]pyri...) Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C#N Show InChI InChI=1S/C18H12ClN7/c19-14-4-2-1-3-13(14)9-26-10-17(22-11-26)15-7-12(5-6-21-15)18-16(8-20)23-25-24-18/h1-7,10-11H,9H2,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276088 (1-(2-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccccc1-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-3-1-2-4-14(9)21-7-13(17-8-21)10-5-11-12(6-16-10)19-20-18-11/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276089 (1-(3-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1cccc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-2-1-3-10(4-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276071 (2-[1-(1-phenylpropan-2-yl)imidazol-4-yl]-4-(1H-tri...) Show SMILES CC(Cc1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276090 (1-(3,5-dichlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c...) Show SMILES Clc1cc(Cl)cc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H8Cl2N6/c15-8-1-9(16)3-10(2-8)22-6-14(18-7-22)11-4-12-13(5-17-11)20-21-19-12/h1-7H,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276091 (5-(4-fluorophenyl)-1-methyl-4-{1H-[1,2,3]triazolo[...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C15H11FN6/c1-22-8-18-14(15(22)9-2-4-10(16)5-3-9)12-6-11-13(7-17-12)20-21-19-11/h2-8H,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276074 (4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...) Show SMILES Clc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1 Show InChI InChI=1S/C22H17ClN6/c23-22-21(26-28-27-22)17-8-10-24-19(12-17)20-13-29(14-25-20)11-9-16-6-3-5-15-4-1-2-7-18(15)16/h1-8,10,12-14H,9,11H2,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276052 (4-[2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]...) Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C#N)c1Cl Show InChI InChI=1S/C18H11Cl2N7/c19-13-3-1-2-12(17(13)20)8-27-9-16(23-10-27)14-6-11(4-5-22-14)18-15(7-21)24-26-25-18/h1-6,9-10H,8H2,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276079 (2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1F |(2.23,-3.53,;.74,-3.92,;-.16,-5.17,;-1.63,-4.69,;-1.63,-3.15,;-.16,-2.68,;.23,-1.19,;-.85,-.1,;-.46,1.39,;1.03,1.78,;1.43,3.27,;2.12,.7,;1.72,-.79,;2.81,-1.88,;4.3,-1.48,;5.39,-2.57,;5.79,-4.06,;6.88,-2.97,;-2.96,-2.38,;-2.96,-.84,;-4.3,-.07,;-5.63,-.84,;-5.63,-2.38,;-4.3,-3.15,;-4.3,1.47,;-3.05,2.37,;-3.53,3.84,;-5.07,3.84,;-5.54,2.37,;-6.88,1.6,)| Show InChI InChI=1S/C21H18F2N6O/c1-29-11-25-19(16-8-13(6-7-24-16)18-21(23)27-28-26-18)20(29)15-5-4-14(22)9-17(15)30-10-12-2-3-12/h4-9,11-12H,2-3,10H2,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276077 (4-[2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1[N+]#[C-] |(2.9,-3.53,;1.41,-3.92,;.5,-5.17,;-.96,-4.69,;-.96,-3.15,;.5,-2.68,;.9,-1.19,;-.19,-.1,;.21,1.39,;1.7,1.78,;2.1,3.27,;2.79,.7,;2.39,-.79,;3.48,-1.88,;4.97,-1.48,;6.05,-2.57,;6.45,-4.06,;7.54,-2.97,;-2.3,-2.38,;-2.3,-.84,;-3.63,-.07,;-4.96,-.84,;-4.96,-2.38,;-3.63,-3.15,;-3.63,1.47,;-2.38,2.37,;-2.86,3.84,;-4.4,3.84,;-4.91,2.36,;-6.38,1.88,;-7.84,1.41,)| Show InChI InChI=1S/C22H18FN7O/c1-24-22-19(27-29-28-22)14-7-8-25-17(9-14)20-21(30(2)12-26-20)16-6-5-15(23)10-18(16)31-11-13-3-4-13/h5-10,12-13H,3-4,11H2,2H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276086 (1-[(3,4-dichlorophenyl)methyl]-4-{1H-[1,2,3]triazo...) Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1Cl Show InChI InChI=1S/C15H10Cl2N6/c16-10-2-1-9(3-11(10)17)6-23-7-15(19-8-23)12-4-13-14(5-18-12)21-22-20-13/h1-5,7-8H,6H2,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276065 (2-[1-[2-(2-phenylphenyl)ethyl]imidazol-4-yl]-4-(1H...) Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C24H20N6/c1-2-6-18(7-3-1)21-9-5-4-8-19(21)11-13-30-16-24(26-17-30)22-14-20(10-12-25-22)23-15-27-29-28-23/h1-10,12,14-17H,11,13H2,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276064 (2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...) Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F Show InChI InChI=1S/C18H12F4N6O/c19-17-12(2-1-3-16(17)29-18(20,21)22)8-28-9-15(24-10-28)13-6-11(4-5-23-13)14-7-25-27-26-14/h1-7,9-10H,8H2,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276063 (2-[5-(3-ethoxy-4-fluorophenyl)-1-methylimidazol-4-...) Show SMILES CCOc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1 Show InChI InChI=1S/C19H17FN6O/c1-3-27-17-9-13(4-5-14(17)20)19-18(22-11-26(19)2)15-8-12(6-7-21-15)16-10-23-25-24-16/h4-11H,3H2,1-2H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276085 (1-[(4-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...) Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1 Show InChI InChI=1S/C15H11ClN6/c16-11-3-1-10(2-4-11)7-22-8-15(18-9-22)12-5-13-14(6-17-12)20-21-19-13/h1-6,8-9H,7H2,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276084 (1-[(3-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...) Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)c1 Show InChI InChI=1S/C15H11ClN6/c16-11-3-1-2-10(4-11)7-22-8-15(18-9-22)12-5-13-14(6-17-12)20-21-19-13/h1-6,8-9H,7H2,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276083 (1-[(2-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...) Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C15H11ClN6/c16-11-4-2-1-3-10(11)7-22-8-15(18-9-22)12-5-13-14(6-17-12)20-21-19-13/h1-6,8-9H,7H2,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276092 (5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-methyl...) Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc2[nH]nnc2cn1 |(2.41,-2.3,;.92,-2.7,;.45,-4.16,;-1.09,-4.16,;-1.57,-2.7,;-.32,-1.79,;.07,-.3,;-1.01,.79,;-.62,2.27,;.87,2.67,;1.27,4.16,;1.96,1.58,;1.56,.1,;2.65,-.99,;4.14,-.59,;5.23,-1.68,;5.63,-3.17,;6.72,-2.08,;-2.9,-1.93,;-2.9,-.39,;-4.24,.38,;-4.56,1.89,;-6.09,2.05,;-6.72,.65,;-5.57,-.39,;-5.57,-1.93,;-4.24,-2.7,)| Show InChI InChI=1S/C19H17FN6O/c1-26-10-22-18(15-7-14-16(8-21-15)24-25-23-14)19(26)13-5-4-12(20)6-17(13)27-9-11-2-3-11/h4-8,10-11H,2-3,9H2,1H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276081 (4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}-1-(2,2,2...) Show SMILES FC(F)(F)Cn1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C10H7F3N6/c11-10(12,13)4-19-3-9(15-5-19)6-1-7-8(2-14-6)17-18-16-7/h1-3,5H,4H2,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276080 (1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...) Show SMILES C(C1CC1)n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C12H12N6/c1-2-8(1)5-18-6-12(14-7-18)9-3-10-11(4-13-9)16-17-15-10/h3-4,6-8H,1-2,5H2,(H,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair

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