Compile Data Set for Download or QSAR

Found 345 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 6382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125254 (US8772480, 65) Show SMILES Cc1nc(-c2cc(cnc2Nc2cccc3[nH]ncc23)C(F)(F)F)c2nc[nH]c2n1 Show InChI InChI=1S/C19H13F3N8/c1-9-27-15(16-18(28-9)25-8-24-16)11-5-10(19(20,21)22)6-23-17(11)29-13-3-2-4-14-12(13)7-26-30-14/h2-8H,1H3,(H,23,29)(H,26,30)(H,24,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125474 (US8772480, 338) Show SMILES Cc1nc(-c2cccnc2Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c2nc[nH]c2n1 Show InChI InChI=1S/C17H15ClN8O2S/c1-9-23-13(14-17(24-9)22-8-21-14)11-4-3-5-19-16(11)25-10-6-12(15(18)20-7-10)26-29(2,27)28/h3-8,26H,1-2H3,(H,19,25)(H,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401253 (CHEMBL2206907 | US8772480, 328) Show SMILES Cc1nc(N)nc(n1)-c1cc(cnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1)C1CCOCC1 Show InChI InChI=1S/C20H23ClN8O3S/c1-11-25-19(28-20(22)26-11)15-7-13(12-3-5-32-6-4-12)9-24-18(15)27-14-8-16(17(21)23-10-14)29-33(2,30)31/h7-10,12,29H,3-6H2,1-2H3,(H,24,27)(H2,22,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125290 (US8772480, 102) Show SMILES CC(=O)Nc1ccc(Nc2ncccc2-c2nc(C)nc3[nH]cnc23)cc1 Show InChI InChI=1S/C19H17N7O/c1-11-23-16(17-19(24-11)22-10-21-17)15-4-3-9-20-18(15)26-14-7-5-13(6-8-14)25-12(2)27/h3-10H,1-2H3,(H,20,26)(H,25,27)(H,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125475 (US8772480, 339) Show SMILES CC(N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc2[nH]cnc12 |w:1.0| Show InChI InChI=1S/C23H26ClN9O3S/c1-13(33-4-6-36-7-5-33)15-8-17(19-20-23(28-12-27-20)30-14(2)29-19)22(26-10-15)31-16-9-18(21(24)25-11-16)32-37(3,34)35/h8-13,32H,4-7H2,1-3H3,(H,26,31)(H,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401257 (CHEMBL2206903 | US8772480, 330) Show SMILES COc1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C16H17ClN8O3S/c1-8-21-15(24-16(18)22-8)11-5-10(28-2)7-20-14(11)23-9-4-12(13(17)19-6-9)25-29(3,26)27/h4-7,25H,1-3H3,(H,20,23)(H2,18,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125353 (US8772480, 182) Show SMILES Cc1nc(-c2cccnc2Nc2ccc(NC(=O)C3CC3)cc2)c2nc[nH]c2n1 Show InChI InChI=1S/C21H19N7O/c1-12-25-17(18-20(26-12)24-11-23-18)16-3-2-10-22-19(16)27-14-6-8-15(9-7-14)28-21(29)13-4-5-13/h2-3,6-11,13H,4-5H2,1H3,(H,22,27)(H,28,29)(H,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401254 (CHEMBL2206906 | US8772480, 335) Show SMILES COCCOc1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C18H21ClN8O4S/c1-10-23-17(26-18(20)24-10)13-7-12(31-5-4-30-2)9-22-16(13)25-11-6-14(15(19)21-8-11)27-32(3,28)29/h6-9,27H,4-5H2,1-3H3,(H,22,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401256 (CHEMBL2206904 | US8772480, 331) Show SMILES COc1cnc(Nc2cnc(Cl)c(NS(=O)(=O)N(C)C)c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C17H20ClN9O3S/c1-9-22-16(25-17(19)23-9)12-6-11(30-4)8-21-15(12)24-10-5-13(14(18)20-7-10)26-31(28,29)27(2)3/h5-8,26H,1-4H3,(H,21,24)(H2,19,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125476 (US8772480, 340) Show SMILES CC(N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(=O)(=O)N(C)C)c2)c(c1)-c1nc(C)nc2[nH]cnc12 |w:1.0| Show InChI InChI=1S/C24H29ClN10O3S/c1-14(35-5-7-38-8-6-35)16-9-18(20-21-24(29-13-28-21)31-15(2)30-20)23(27-11-16)32-17-10-19(22(25)26-12-17)33-39(36,37)34(3)4/h9-14,33H,5-8H2,1-4H3,(H,27,32)(H,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125514 (US8772480, 106) Show SMILES Cc1nc(-c2cc(Cc3ccc(cc3)S(C)(=O)=O)cnc2Nc2ccc(N)nc2)c2nc[nH]c2n1 Show InChI InChI=1S/C24H22N8O2S/c1-14-30-21(22-24(31-14)29-13-28-22)19-10-16(9-15-3-6-18(7-4-15)35(2,33)34)11-27-23(19)32-17-5-8-20(25)26-12-17/h3-8,10-13H,9H2,1-2H3,(H2,25,26)(H,27,32)(H,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125455 (US8772480, 310) Show SMILES C[C@@H](N1CCN(CC1)S(C)(=O)=O)c1cnc(Nc2ccc3cccnc3c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C25H29N9O2S/c1-16(33-9-11-34(12-10-33)37(3,35)36)19-13-21(24-29-17(2)30-25(26)32-24)23(28-15-19)31-20-7-6-18-5-4-8-27-22(18)14-20/h4-8,13-16H,9-12H2,1-3H3,(H,28,31)(H2,26,29,30,32)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125314 (US8772480, 132) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc3[nH]cnc23)[C@@H](O)C(C)(C)C)cn1 |r| Show InChI InChI=1S/C22H25N7O2/c1-12-27-17(18-21(28-12)26-11-25-18)15-8-13(19(30)22(2,3)4)9-24-20(15)29-14-6-7-16(31-5)23-10-14/h6-11,19,30H,1-5H3,(H,24,29)(H,25,26,27,28)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401252 (CHEMBL2206908 | US8772480, 332) Show SMILES Cc1nc(N)nc(n1)-c1cc(CN2CCOCC2)cnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C20H24ClN9O3S/c1-12-25-19(28-20(22)26-12)15-7-13(11-30-3-5-33-6-4-30)9-24-18(15)27-14-8-16(17(21)23-10-14)29-34(2,31)32/h7-10,29H,3-6,11H2,1-2H3,(H,24,27)(H2,22,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125420 (US8772480, 268) Show SMILES CC(=O)Nc1ccc(Nc2ncc(CN3CCN(CC3)S(C)(=O)=O)cc2-c2nc(C)nc(N)n2)cc1 Show InChI InChI=1S/C23H29N9O3S/c1-15-26-22(30-23(24)27-15)20-12-17(14-31-8-10-32(11-9-31)36(3,34)35)13-25-21(20)29-19-6-4-18(5-7-19)28-16(2)33/h4-7,12-13H,8-11,14H2,1-3H3,(H,25,29)(H,28,33)(H2,24,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401261 (CHEMBL2206921 | US8772480, 384) Show SMILES CN(C)S(=O)(=O)Nc1cc(Nc2ncc(Cl)cc2-c2nc(C)nc(N)n2)cnc1Cl Show InChI InChI=1S/C16H17Cl2N9O2S/c1-8-22-15(25-16(19)23-8)11-4-9(17)6-21-14(11)24-10-5-12(13(18)20-7-10)26-30(28,29)27(2)3/h4-7,26H,1-3H3,(H,21,24)(H2,19,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125231 (US8772480, 30) Show SMILES Cc1nc(N)nc(n1)-c1cc(CN2CCN(CC2)S(C)(=O)=O)cnc1Nc1cccc(O)c1 Show InChI InChI=1S/C21H26N8O3S/c1-14-24-20(27-21(22)25-14)18-10-15(13-28-6-8-29(9-7-28)33(2,31)32)12-23-19(18)26-16-4-3-5-17(30)11-16/h3-5,10-12,30H,6-9,13H2,1-2H3,(H,23,26)(H2,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125287 (US8772480, 99) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc3[nH]cnc23)N2CCN(CC2)S(C)(=O)=O)cn1 Show InChI InChI=1S/C22H25N9O3S/c1-14-27-19(20-22(28-14)26-13-25-20)17-10-16(30-6-8-31(9-7-30)35(3,32)33)12-24-21(17)29-15-4-5-18(34-2)23-11-15/h4-5,10-13H,6-9H2,1-3H3,(H,24,29)(H,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50394891 (CHEMBL2165052 | US8772480, 23) Show SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cccc(O)c1 Show InChI InChI=1S/C15H14N6O/c1-9-18-14(21-15(16)19-9)12-6-3-7-17-13(12)20-10-4-2-5-11(22)8-10/h2-8,22H,1H3,(H,17,20)(H2,16,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125436 (US8772480, 290) Show SMILES CC(N1CCN(CC1)S(C)(=O)=O)c1cnc(Nc2ccc3scnc3c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C23H27N9O2S2/c1-14(31-6-8-32(9-7-31)36(3,33)34)16-10-18(22-27-15(2)28-23(24)30-22)21(25-12-16)29-17-4-5-20-19(11-17)26-13-35-20/h4-5,10-14H,6-9H2,1-3H3,(H,25,29)(H2,24,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125434 (US8772480, 288) Show SMILES CC(N1CCOCC1)c1cnc(Nc2ccc3scnc3c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C22H24N8OS/c1-13(30-5-7-31-8-6-30)15-9-17(21-26-14(2)27-22(23)29-21)20(24-11-15)28-16-3-4-19-18(10-16)25-12-32-19/h3-4,9-13H,5-8H2,1-2H3,(H,24,28)(H2,23,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125443 (US8772480, 298) Show SMILES COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C2(O)CC2)cc1F Show InChI InChI=1S/C18H18FN7O2/c1-9-23-15(26-17(20)24-9)12-5-10(18(27)3-4-18)7-21-14(12)25-11-6-13(19)16(28-2)22-8-11/h5-8,27H,3-4H2,1-2H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125291 (US8772480, 103) Show SMILES COc1ccc(Nc2ncc(Cc3ccc(cc3)S(C)(=O)=O)cc2-c2nc(C)nc3[nH]cnc23)cn1 Show InChI InChI=1S/C25H23N7O3S/c1-15-30-22(23-25(31-15)29-14-28-23)20-11-17(10-16-4-7-19(8-5-16)36(3,33)34)12-27-24(20)32-18-6-9-21(35-2)26-13-18/h4-9,11-14H,10H2,1-3H3,(H,27,32)(H,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125263 (US8772480, 75) Show SMILES COc1ccc(Nc2ncc(CCO)cc2-c2nc(C)nc3[nH]cnc23)cn1 Show InChI InChI=1S/C19H19N7O2/c1-11-24-16(17-19(25-11)23-10-22-17)14-7-12(5-6-27)8-21-18(14)26-13-3-4-15(28-2)20-9-13/h3-4,7-10,27H,5-6H2,1-2H3,(H,21,26)(H,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125516 (US8772480, 133) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc3[nH]cnc23)[C@H](O)C(C)(C)C)cn1 |r| Show InChI InChI=1S/C22H25N7O2/c1-12-27-17(18-21(28-12)26-11-25-18)15-8-13(19(30)22(2,3)4)9-24-20(15)29-14-6-7-16(31-5)23-10-14/h6-11,19,30H,1-5H3,(H,24,29)(H,25,26,27,28)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125438 (US8772480, 293) Show SMILES C[C@@H](N1CCN(C[C@@H]1C)S(C)(=O)=O)c1cnc(Nc2ccc3scnc3c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C24H29N9O2S2/c1-14-12-32(37(4,34)35)7-8-33(14)15(2)17-9-19(23-28-16(3)29-24(25)31-23)22(26-11-17)30-18-5-6-21-20(10-18)27-13-36-21/h5-6,9-11,13-15H,7-8,12H2,1-4H3,(H,26,30)(H2,25,28,29,31)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125499 (US8772480, 368) Show SMILES COc1cnc(Nc2cnc(Cl)c(N)c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C15H15ClN8O/c1-7-21-14(24-15(18)22-7)10-4-9(25-2)6-20-13(10)23-8-3-11(17)12(16)19-5-8/h3-6H,17H2,1-2H3,(H,20,23)(H2,18,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125465 (US8772480, 320) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)(O)C(F)(F)F)cn1 Show InChI InChI=1S/C18H18F3N7O2/c1-9-25-15(28-16(22)26-9)12-6-10(17(2,29)18(19,20)21)7-24-14(12)27-11-4-5-13(30-3)23-8-11/h4-8,29H,1-3H3,(H,24,27)(H2,22,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125510 (US8772480, 380) Show SMILES Cc1nc(N)cc(n1)-c1cc(C=C)cnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C18H18ClN7O2S/c1-4-11-5-13(14-7-16(20)24-10(2)23-14)18(22-8-11)25-12-6-15(17(19)21-9-12)26-29(3,27)28/h4-9,26H,1H2,2-3H3,(H,22,25)(H2,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125313 (US8772480, 131) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc3[nH]cnc23)C(O)C(C)(C)C)cn1 Show InChI InChI=1S/C22H25N7O2/c1-12-27-17(18-21(28-12)26-11-25-18)15-8-13(19(30)22(2,3)4)9-24-20(15)29-14-6-7-16(31-5)23-10-14/h6-11,19,30H,1-5H3,(H,24,29)(H,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125293 (US8772480, 105) Show SMILES CC(=O)Nc1ccc(Nc2ncc(Cc3ccc(cc3)S(C)(=O)=O)cc2-c2nc(C)nc3[nH]cnc23)cn1 Show InChI InChI=1S/C26H24N8O3S/c1-15-31-23(24-26(32-15)30-14-29-24)21-11-18(10-17-4-7-20(8-5-17)38(3,36)37)12-28-25(21)34-19-6-9-22(27-13-19)33-16(2)35/h4-9,11-14H,10H2,1-3H3,(H,28,34)(H,27,33,35)(H,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50394881 (CHEMBL2165039 | US8772480, 58) Show SMILES COc1ccc(Nc2ncccc2-c2nc(C)nc3nc[nH]c23)cn1 Show InChI InChI=1S/C17H15N7O/c1-10-22-14(15-17(23-10)21-9-20-15)12-4-3-7-18-16(12)24-11-5-6-13(25-2)19-8-11/h3-9H,1-2H3,(H,18,24)(H,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	292	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125504 (US8772480, 373) Show SMILES C[C@@H](N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(=O)(=O)N(C)C)c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C22H29ClN10O3S/c1-13(33-5-7-36-8-6-33)15-9-17(21-27-14(2)28-22(24)30-21)20(26-11-15)29-16-10-18(19(23)25-12-16)31-37(34,35)32(3)4/h9-13,31H,5-8H2,1-4H3,(H,26,29)(H2,24,27,28,30)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125502 (US8772480, 371) Show SMILES C[C@@H](N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C21H26ClN9O3S/c1-12(31-4-6-34-7-5-31)14-8-16(20-26-13(2)27-21(23)29-20)19(25-10-14)28-15-9-17(18(22)24-11-15)30-35(3,32)33/h8-12,30H,4-7H2,1-3H3,(H,25,28)(H2,23,26,27,29)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125435 (US8772480, 289) Show SMILES CC(N1CCN(CC1)C(=O)N(C)C)c1cnc(Nc2ccc3scnc3c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C25H30N10OS/c1-15(34-7-9-35(10-8-34)25(36)33(3)4)17-11-19(23-29-16(2)30-24(26)32-23)22(27-13-17)31-18-5-6-21-20(12-18)28-14-37-21/h5-6,11-15H,7-10H2,1-4H3,(H,27,31)(H2,26,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	326	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125503 (US8772480, 372) Show SMILES C[C@H](N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C21H26ClN9O3S/c1-12(31-4-6-34-7-5-31)14-8-16(20-26-13(2)27-21(23)29-20)19(25-10-14)28-15-9-17(18(22)24-11-15)30-35(3,32)33/h8-12,30H,4-7H2,1-3H3,(H,25,28)(H2,23,26,27,29)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401268 (CHEMBL2206914 | US8772480, 365) Show SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cnc(Cl)c(NS(=O)(=O)C2CC2)c1 Show InChI InChI=1S/C17H17ClN8O2S/c1-9-22-16(25-17(19)23-9)12-3-2-6-20-15(12)24-10-7-13(14(18)21-8-10)26-29(27,28)11-4-5-11/h2-3,6-8,11,26H,4-5H2,1H3,(H,20,24)(H2,19,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125274 (US8772480, 86) Show SMILES COC(=O)N1CCN(Cc2cnc(Nc3ccc(OC)nc3)c(c2)-c2nc(C)nc3[nH]cnc23)CC1 Show InChI InChI=1S/C24H27N9O3/c1-15-29-20(21-23(30-15)28-14-27-21)18-10-16(13-32-6-8-33(9-7-32)24(34)36-3)11-26-22(18)31-17-4-5-19(35-2)25-12-17/h4-5,10-12,14H,6-9,13H2,1-3H3,(H,26,31)(H,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	346	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125265 (US8772480, 77) Show SMILES COc1ccc(NCc2cnc(Nc3ccc(OC)nc3)c(c2)-c2nc(C)nc3[nH]cnc23)cc1 Show InChI InChI=1S/C25H24N8O2/c1-15-31-22(23-25(32-15)30-14-29-23)20-10-16(11-26-17-4-7-19(34-2)8-5-17)12-28-24(20)33-18-6-9-21(35-3)27-13-18/h4-10,12-14,26H,11H2,1-3H3,(H,28,33)(H,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125521 (US8772480, 323) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)[C@H](O)C(F)(F)F)cn1 |r| Show InChI InChI=1S/C17H16F3N7O2/c1-8-24-15(27-16(21)25-8)11-5-9(13(28)17(18,19)20)6-23-14(11)26-10-3-4-12(29-2)22-7-10/h3-7,13,28H,1-2H3,(H,23,26)(H2,21,24,25,27)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	379	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125505 (US8772480, 374) Show SMILES C[C@H](N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(=O)(=O)N(C)C)c2)c(c1)-c1nc(C)nc(N)n1 |r| Show InChI InChI=1S/C22H29ClN10O3S/c1-13(33-5-7-36-8-6-33)15-9-17(21-27-14(2)28-22(24)30-21)20(26-11-15)29-16-10-18(19(23)25-12-16)31-37(34,35)32(3)4/h9-13,31H,5-8H2,1-4H3,(H,26,29)(H2,24,27,28,30)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125401 (US8772480, 244) Show SMILES Cc1nc(N)nc(n1)-c1cc(CN2CCN(CC2)S(C)(=O)=O)cnc1Nc1cc[nH]n1 Show InChI InChI=1S/C18H24N10O2S/c1-12-22-17(25-18(19)23-12)14-9-13(10-20-16(14)24-15-3-4-21-26-15)11-27-5-7-28(8-6-27)31(2,29)30/h3-4,9-10H,5-8,11H2,1-2H3,(H2,19,22,23,25)(H2,20,21,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401270 (CHEMBL2206912 | US8772480, 264) Show SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C20H16ClFN8O2S/c1-11-26-19(29-20(23)27-11)15-3-2-8-24-18(15)28-13-9-16(17(21)25-10-13)30-33(31,32)14-6-4-12(22)5-7-14/h2-10,30H,1H3,(H,24,28)(H2,23,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401265 (CHEMBL2206917 | US8772480, 366) Show SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cnc(Cl)c(NS(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C18H20ClN9O3S/c1-11-23-17(26-18(20)24-11)13-3-2-4-21-16(13)25-12-9-14(15(19)22-10-12)27-32(29,30)28-5-7-31-8-6-28/h2-4,9-10,27H,5-8H2,1H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	416	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401266 (CHEMBL2206916 | US8772480, 367) Show SMILES CC(C)N(C)S(=O)(=O)Nc1cc(Nc2ncccc2-c2nc(C)nc(N)n2)cnc1Cl Show InChI InChI=1S/C18H22ClN9O2S/c1-10(2)28(4)31(29,30)27-14-8-12(9-22-15(14)19)25-16-13(6-5-7-21-16)17-23-11(3)24-18(20)26-17/h5-10,27H,1-4H3,(H,21,25)(H2,20,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125255 (US8772480, 66) Show SMILES COc1ncc(Nc2ncccc2-c2nc(C)nc3[nH]cnc23)cn1 Show InChI InChI=1S/C16H14N8O/c1-9-22-12(13-15(23-9)21-8-20-13)11-4-3-5-17-14(11)24-10-6-18-16(25-2)19-7-10/h3-8H,1-2H3,(H,17,24)(H,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	426	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125449 (US8772480, 304) Show SMILES Cc1nc(N)cc(n1)-c1cccnc1Nc1cnc(Cl)c(NS(C)(=O)=O)c1 Show InChI InChI=1S/C16H16ClN7O2S/c1-9-21-12(7-14(18)22-9)11-4-3-5-19-16(11)23-10-6-13(15(17)20-8-10)24-27(2,25)26/h3-8,24H,1-2H3,(H,19,23)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	444	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125418 (US8772480, 266) Show SMILES CC(=O)Nc1ccc(Nc2ncc(Cl)cc2-c2nc(C)nc(N)n2)cc1F Show InChI InChI=1S/C17H15ClFN7O/c1-8-22-16(26-17(20)23-8)12-5-10(18)7-21-15(12)25-11-3-4-14(13(19)6-11)24-9(2)27/h3-7H,1-2H3,(H,21,25)(H,24,27)(H2,20,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	463	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50401249 (CHEMBL2206911 | US8772480, 265) Show SMILES Cc1nc(N)nc(n1)-c1cccnc1Nc1cnc(Cl)c(N)c1 Show InChI InChI=1S/C14H13ClN8/c1-7-20-13(23-14(17)21-7)9-3-2-4-18-12(9)22-8-5-10(16)11(15)19-6-8/h2-6H,16H2,1H3,(H,18,22)(H2,17,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	471	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM125500 (US8772480, 369) Show SMILES CC(N1CCOCC1)c1cnc(Nc2cnc(Cl)c(NS(C)(=O)=O)c2)c(c1)-c1nc(C)nc(N)n1 Show InChI InChI=1S/C21H26ClN9O3S/c1-12(31-4-6-34-7-5-31)14-8-16(20-26-13(2)27-21(23)29-20)19(25-10-14)28-15-9-17(18(22)24-11-15)30-35(3,32)33/h8-12,30H,4-7H2,1-3H3,(H,25,28)(H2,23,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	472	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8772480 (2014) BindingDB Entry DOI: 10.7270/Q2V123FJ
					More data for this Ligand-Target Pair

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