Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329205 (5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329211 (5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329203 (5-(4-chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329206 (5-(4-chlorophenyl)-N-((2-ethoxypyridin-3-yl)methyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329217 (CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329209 (5-(4-chlorophenyl)-N-(2-(piperidin-1-yl)benzyl)nic...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329210 (CHEMBL1269883 | N-(2-chlorobenzyl)-5-(4-chlorophen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329212 (CHEMBL1271417 | N-benzyl-5-(4-chlorophenyl)nicotin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329213 (5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329202 (5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329215 (CHEMBL1271206 | N-(3,5-dimethylphenyl)-5-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329204 (5-(4-chlorophenyl)-N-((2-morpholinopyridin-3-yl)me...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50212239 (5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329208 (5-(4-chlorophenyl)-N-(2-morpholinobenzyl)nicotinam...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329223 (CHEMBL1270797 | N-(3,5-dimethylphenyl)-5-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329214 (CHEMBL1271415 | N-(3,5-dimethylphenyl)-5-(4-fluoro...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329219 (CHEMBL1270999 | N-(3,5-dimethylphenyl)-2-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329216 (CHEMBL1271205 | N-(3,5-dimethylphenyl)-6-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329218 (CHEMBL1271105 | N-(3,5-dimethylphenyl)-5-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329207 (5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329220 (CHEMBL1270998 | N-(3,5-dimethylphenyl)-3-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329222 (CHEMBL1270898 | N-(3,5-dimethylphenyl)-2-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM50329221 (CHEMBL1270899 | N-(3,5-dimethylphenyl)-2-(4-(trifl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology | Bioorg Med Chem Lett 20: 6812-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.121 BindingDB Entry DOI: 10.7270/Q2F76CS6 | |||||||||||
More data for this Ligand-Target Pair |