Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50105033 (CHEMBL112531 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.00420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cells | J Med Chem 44: 3369-77 (2001) BindingDB Entry DOI: 10.7270/Q27M08P8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50369953 (CHEMBL1627022) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cells | J Med Chem 44: 3369-77 (2001) BindingDB Entry DOI: 10.7270/Q27M08P8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50105000 (CHEMBL175616 | sodium salt of 4-tert-Butyl-N-[6-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cells | J Med Chem 44: 3369-77 (2001) BindingDB Entry DOI: 10.7270/Q27M08P8 | |||||||||||
More data for this Ligand-Target Pair |