Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303498 (1-(2-Oxo-2H-chromen-6-ylmethyl)-3,5,7-triaza-1-azo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303494 (CHEMBL568173 | ethyl 6-(hydroxymethyl)-2-oxo-2H-ch...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303493 (CHEMBL567896 | methyl 6-(hydroxymethyl)-2-oxo-2H-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303497 (6-(aminomethyl)-2H-chromen-2-one | CHEMBL567139) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM12342 (2H-chromen-2-one | CHEMBL6466 | Coumarin) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303491 (8-methoxy-2-oxo-2H-chromene-3-carboxylic acid | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303489 (6-methoxy-2-oxo-2H-chromene-3-carboxylic acid | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303490 (6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50378564 (CHEMBL145781) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303495 (CHEMBL568385 | ethyl 7-methoxy-2-oxo-2H-chromene-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303496 (6-(hydroxymethyl)-2H-chromen-2-one | CHEMBL571738) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50300203 ((S)-6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chrom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303492 (2-oxo-2H-thiochromene-3-carboxylic acid | CHEMBL57...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50131066 (2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303487 (7-phenethoxy-2H-chromen-2-one | CHEMBL567544) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303501 (7-propoxy-2H-chromen-2-one | CHEMBL568516) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303488 (6-methyl-2-oxo-2H-chromene-3-carboxylic acid | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303502 (7-butoxy-2H-chromen-2-one | CHEMBL571514) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50022188 (7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303500 (7-ethoxy-2H-1-benzopyran-2-one | 7-ethoxycoumarin ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM50303499 (7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assay | J Med Chem 53: 335-44 (2010) Article DOI: 10.1021/jm901287j BindingDB Entry DOI: 10.7270/Q2MS3TP5 | |||||||||||
More data for this Ligand-Target Pair |