Compile Data Set for Download or QSAR

Found 93 hits Enz. Inhib. hit(s) with all data for assayid = 3 entry = 7598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM142598 (US10238658, Example Reference | US10813932, Refere...) Show SMILES COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1 Show InChI InChI=1S/C33H34N6O4/c1-21-10-12-22(13-11-21)39-30(19-28(38-39)33(2,3)4)37-32(41)35-26-14-15-27(25-9-7-6-8-24(25)26)43-23-16-17-34-29(18-23)36-31(40)20-42-5/h6-19H,20H2,1-5H3,(H,34,36,40)(H2,35,37,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205310 (US9249125, 63) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CNC(=O)c5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C42H43N9O5/c1-42(2,3)36-25-37(51(49-36)29-10-12-30(13-11-29)55-23-20-50-18-21-54-22-19-50)47-41(53)46-34-14-15-35(32-7-5-4-6-31(32)34)56-38-16-17-43-40(48-38)45-28-9-8-27-26-44-39(52)33(27)24-28/h4-17,24-25H,18-23,26H2,1-3H3,(H,44,52)(H,43,45,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205291 (US9249125, 44) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(OCCN5CCOCC5)c4c3)n2)c2ccccc12)C(C)C Show InChI InChI=1S/C41H42N10O5/c1-26(2)35-25-37(51(49-35)28-9-11-29(53-3)12-10-28)45-41(52)44-33-14-15-36(31-7-5-4-6-30(31)33)56-38-16-17-42-40(46-38)43-27-8-13-34-32(24-27)39(48-47-34)55-23-20-50-18-21-54-22-19-50/h4-17,24-26H,18-23H2,1-3H3,(H,47,48)(H,42,43,46)(H2,44,45,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205337 (US9249125, 90) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CC(=O)Nc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)nc1 Show InChI InChI=1S/C41H42N10O5/c1-41(2,3)34-24-35(51(49-34)28-10-13-37(43-25-28)55-21-18-50-16-19-54-20-17-50)47-40(53)46-31-11-12-33(30-7-5-4-6-29(30)31)56-38-14-15-42-39(48-38)44-27-9-8-26-22-36(52)45-32(26)23-27/h4-15,23-25H,16-22H2,1-3H3,(H,45,52)(H,42,44,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205331 (US9249125, 84) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3cc(Nc4ccc5[nH]ncc5c4)ncn3)c3ccccc23)n(n1)-c1ccc(=O)n(CCO)c1 Show InChI InChI=1S/C35H32N10O4/c1-21(2)29-16-32(45(43-29)24-8-12-34(47)44(19-24)13-14-46)41-35(48)40-28-10-11-30(26-6-4-3-5-25(26)28)49-33-17-31(36-20-37-33)39-23-7-9-27-22(15-23)18-38-42-27/h3-12,15-21,46H,13-14H2,1-2H3,(H,38,42)(H,36,37,39)(H2,40,41,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205277 (US9249125, 30) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]cnc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H33N9O2/c1-22-9-12-24(13-10-22)45-32(20-31(44-45)36(2,3)4)42-35(46)41-27-15-16-30(26-8-6-5-7-25(26)27)47-33-17-18-37-34(43-33)40-23-11-14-28-29(19-23)39-21-38-28/h5-21H,1-4H3,(H,38,39)(H,37,40,43)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	301	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205292 (US9249125, 45) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(OCCN5CCOCC5)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C42H44N10O5/c1-42(2,3)36-26-37(52(50-36)28-10-12-29(54-4)13-11-28)46-41(53)45-33-15-16-35(31-8-6-5-7-30(31)33)57-38-17-18-43-40(47-38)44-27-9-14-34-32(25-27)39(49-48-34)56-24-21-51-19-22-55-23-20-51/h5-18,25-26H,19-24H2,1-4H3,(H,48,49)(H,43,44,47)(H2,45,46,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205311 (US9249125, 64) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CS(=O)(=O)Cc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C42H44N8O6S/c1-42(2,3)37-25-38(50(48-37)31-10-12-32(13-11-31)55-23-20-49-18-21-54-22-19-49)46-41(51)45-35-14-15-36(34-7-5-4-6-33(34)35)56-39-16-17-43-40(47-39)44-30-9-8-28-26-57(52,53)27-29(28)24-30/h4-17,24-25H,18-23,26-27H2,1-3H3,(H,43,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	437	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205327 (US9249125, 80) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5ncsc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H41N9O4S/c1-41(2,3)36-25-37(50(48-36)28-9-11-29(12-10-28)53-23-20-49-18-21-52-22-19-49)46-40(51)45-32-14-15-34(31-7-5-4-6-30(31)32)54-38-16-17-42-39(47-38)44-27-8-13-33-35(24-27)55-26-43-33/h4-17,24-26H,18-23H2,1-3H3,(H,42,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	461	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205294 (US9249125, 47) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)N(C)C)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C39H38N10O4/c1-39(2,3)32-22-33(49(47-32)24-12-14-25(52-6)15-13-24)43-38(51)42-29-17-18-31(27-10-8-7-9-26(27)29)53-34-19-20-40-37(44-34)41-23-11-16-30-28(21-23)35(46-45-30)36(50)48(4)5/h7-22H,1-6H3,(H,45,46)(H,40,41,44)(H2,42,43,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	472	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205290 (US9249125, 43) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4n(CCN5CCOCC5)ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C42H44N10O4/c1-42(2,3)37-26-38(52(49-37)30-10-12-31(54-4)13-11-30)47-41(53)46-34-14-16-36(33-8-6-5-7-32(33)34)56-39-17-18-43-40(48-39)45-29-9-15-35-28(25-29)27-44-51(35)20-19-50-21-23-55-24-22-50/h5-18,25-27H,19-24H2,1-4H3,(H,43,45,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205339 (US9249125, 92) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5n(CCN6CCOCC6)ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)nc1 Show InChI InChI=1S/C46H52N12O5/c1-46(2,3)40-29-41(58(54-40)34-9-13-42(48-31-34)62-27-22-56-20-25-61-26-21-56)52-45(59)51-37-10-12-39(36-7-5-4-6-35(36)37)63-43-14-15-47-44(53-43)50-33-8-11-38-32(28-33)30-49-57(38)17-16-55-18-23-60-24-19-55/h4-15,28-31H,16-27H2,1-3H3,(H,47,50,53)(H2,51,52,59)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	569	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205276 (US9249125, 29) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4n(CCN5CCOCC5)ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C42H44N10O3/c1-28-9-12-31(13-10-28)52-38(26-37(49-52)42(2,3)4)47-41(53)46-34-14-16-36(33-8-6-5-7-32(33)34)55-39-17-18-43-40(48-39)45-30-11-15-35-29(25-30)27-44-51(35)20-19-50-21-23-54-24-22-50/h5-18,25-27H,19-24H2,1-4H3,(H,43,45,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205257 (US9249125, 10) Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CN5CCCC5=O)c4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12 Show InChI InChI=1S/C41H40N10O3/c1-25-19-28(21-27-23-43-48-38(25)27)44-39-42-17-16-36(47-39)54-33-15-14-32(30-11-5-6-12-31(30)33)45-40(53)46-35-22-34(41(2,3)4)49-51(35)29-10-7-9-26(20-29)24-50-18-8-13-37(50)52/h5-7,9-12,14-17,19-23H,8,13,18,24H2,1-4H3,(H,43,48)(H,42,44,47)(H2,45,46,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205321 (US9249125, 74) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5n(CCN6CCOCC6)ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C47H53N11O5/c1-47(2,3)42-31-43(58(54-42)35-9-11-36(12-10-35)62-29-24-56-22-27-61-28-23-56)52-46(59)51-39-13-15-41(38-7-5-4-6-37(38)39)63-44-16-17-48-45(53-44)50-34-8-14-40-33(30-34)32-49-57(40)19-18-55-20-25-60-26-21-55/h4-17,30-32H,18-29H2,1-3H3,(H,48,50,53)(H2,51,52,59)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	597	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205328 (US9249125, 81) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]nnc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C40H41N11O4/c1-40(2,3)35-25-36(51(48-35)27-9-11-28(12-10-27)54-23-20-50-18-21-53-22-19-50)44-39(52)43-31-14-15-34(30-7-5-4-6-29(30)31)55-37-16-17-41-38(45-37)42-26-8-13-32-33(24-26)47-49-46-32/h4-17,24-25H,18-23H2,1-3H3,(H,41,42,45)(H2,43,44,52)(H,46,47,49)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	641	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205307 (US9249125, 60) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5COCc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C42H44N8O5/c1-42(2,3)37-25-38(50(48-37)31-10-12-32(13-11-31)54-23-20-49-18-21-52-22-19-49)46-41(51)45-35-14-15-36(34-7-5-4-6-33(34)35)55-39-16-17-43-40(47-39)44-30-9-8-28-26-53-27-29(28)24-30/h4-17,24-25H,18-23,26-27H2,1-3H3,(H,43,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	686	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205326 (US9249125, 79) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5scnc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H41N9O4S/c1-41(2,3)36-25-37(50(48-36)28-9-11-29(12-10-28)53-23-20-49-18-21-52-22-19-49)46-40(51)45-32-13-14-34(31-7-5-4-6-30(31)32)54-38-16-17-42-39(47-38)44-27-8-15-35-33(24-27)43-26-55-35/h4-17,24-26H,18-23H2,1-3H3,(H,42,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205323 (US9249125, 76) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5oc(=O)[nH]c5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H40N9O6/c1-41(2,3)35-25-36(50(48-35)27-9-11-28(12-10-27)54-23-20-49-18-21-53-22-19-49)46-39(51)44-31-13-15-33(30-7-5-4-6-29(30)31)55-37-16-17-42-38(47-37)43-26-8-14-34-32(24-26)45-40(52)56-34/h4-17,24-25H,18-23H2,1-3H3,(H,42,43,47)(H2,44,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	777	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205333 (US9249125, 86) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(=O)n(CCO)c1 Show InChI InChI=1S/C36H34N10O4/c1-36(2,3)30-19-31(46(44-30)24-9-13-33(48)45(21-24)16-17-47)41-35(49)40-28-11-12-29(26-7-5-4-6-25(26)28)50-32-14-15-37-34(42-32)39-23-8-10-27-22(18-23)20-38-43-27/h4-15,18-21,47H,16-17H2,1-3H3,(H,38,43)(H,37,39,42)(H2,40,41,49)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205255 (US9249125, 8) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ncc4c3)n2)c2ccccc12)C1CCOC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	837	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205258 (US9249125, 11) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5OCCOc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C42H44N8O6/c1-42(2,3)37-27-38(50(48-37)29-9-11-30(12-10-29)53-23-20-49-18-21-52-22-19-49)46-41(51)45-33-13-15-34(32-7-5-4-6-31(32)33)56-39-16-17-43-40(47-39)44-28-8-14-35-36(26-28)55-25-24-54-35/h4-17,26-27H,18-25H2,1-3H3,(H,43,44,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	848	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205267 (US9249125, 20) Show SMILES CN1C(=O)Cc2cc(Nc3nccc(Oc4ccc(NC(=O)Nc5cc(nn5-c5ccc(C)cc5)C(C)(C)C)c5ccccc45)n3)ccc12 Show InChI InChI=1S/C38H36N8O3/c1-23-10-13-26(14-11-23)46-33(22-32(44-46)38(2,3)4)42-37(48)41-29-15-17-31(28-9-7-6-8-27(28)29)49-34-18-19-39-36(43-34)40-25-12-16-30-24(20-25)21-35(47)45(30)5/h6-20,22H,21H2,1-5H3,(H,39,40,43)(H2,41,42,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205293 (US9249125, 46) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)N(C)C)c4c3)n2)c2ccccc12)C(C)C Show InChI InChI=1S/C38H36N10O4/c1-22(2)31-21-33(48(46-31)24-11-13-25(51-5)14-12-24)42-38(50)41-29-16-17-32(27-9-7-6-8-26(27)29)52-34-18-19-39-37(43-34)40-23-10-15-30-28(20-23)35(45-44-30)36(49)47(3)4/h6-22H,1-5H3,(H,44,45)(H,39,40,43)(H2,41,42,50)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	908	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205266 (US9249125, 19) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4NC(=O)Cc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H34N8O3/c1-22-9-12-25(13-10-22)45-32(21-31(44-45)37(2,3)4)42-36(47)41-29-15-16-30(27-8-6-5-7-26(27)29)48-34-17-18-38-35(43-34)39-24-11-14-28-23(19-24)20-33(46)40-28/h5-19,21H,20H2,1-4H3,(H,40,46)(H,38,39,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205343 (US9249125, 14) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(Nc4ccc5[nH]ncc5c4)ncn3)c3ccccc23)n(n1)-c1ccc(=O)n(CCO)c1 Show InChI InChI=1S/C36H34N10O4/c1-36(2,3)30-17-32(46(44-30)24-9-13-34(48)45(20-24)14-15-47)42-35(49)41-28-11-12-29(26-7-5-4-6-25(26)28)50-33-18-31(37-21-38-33)40-23-8-10-27-22(16-23)19-39-43-27/h4-13,16-21,47H,14-15H2,1-3H3,(H,39,43)(H,37,38,40)(H2,41,42,49)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205334 (US9249125, 87) Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(=O)n(CCO)c4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12 Show InChI InChI=1S/C37H36N10O4/c1-22-17-24(18-23-20-39-44-34(22)23)40-35-38-14-13-32(43-35)51-29-11-10-28(26-7-5-6-8-27(26)29)41-36(50)42-31-19-30(37(2,3)4)45-47(31)25-9-12-33(49)46(21-25)15-16-48/h5-14,17-21,48H,15-16H2,1-4H3,(H,39,44)(H,38,40,43)(H2,41,42,50)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205297 (US9249125, 50) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CC(=O)Nc5c4)n3)c3ccccc23)n(n1)-c1cccc(OCCN2CCOCC2)c1 Show InChI InChI=1S/C42H43N9O5/c1-42(2,3)36-26-37(51(49-36)29-7-6-8-30(25-29)55-22-19-50-17-20-54-21-18-50)47-41(53)46-33-13-14-35(32-10-5-4-9-31(32)33)56-39-15-16-43-40(48-39)44-28-12-11-27-23-38(52)45-34(27)24-28/h4-16,24-26H,17-23H2,1-3H3,(H,45,52)(H,43,44,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205338 (US9249125, 91) Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(OCCN5CCOCC5)nc4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12 Show InChI InChI=1S/C41H43N11O4/c1-26-21-28(22-27-24-44-49-38(26)27)45-39-42-14-13-37(48-39)56-33-11-10-32(30-7-5-6-8-31(30)33)46-40(53)47-35-23-34(41(2,3)4)50-52(35)29-9-12-36(43-25-29)55-20-17-51-15-18-54-19-16-51/h5-14,21-25H,15-20H2,1-4H3,(H,44,49)(H,42,45,48)(H2,46,47,53)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205305 (US9249125, 58) Show SMILES CN(C)CCOc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C)c4[nH]ncc4c3)c2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C41H43N9O3/c1-26-21-28(22-27-25-43-47-39(26)27)44-37-23-31(17-18-42-37)53-35-16-15-34(32-9-7-8-10-33(32)35)45-40(51)46-38-24-36(41(2,3)4)48-50(38)29-11-13-30(14-12-29)52-20-19-49(5)6/h7-18,21-25H,19-20H2,1-6H3,(H,42,44)(H,43,47)(H2,45,46,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205316 (US9249125, 69) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C40H40N10O4/c1-26(2)35-24-37(50(48-35)29-8-10-30(11-9-29)53-22-19-49-17-20-52-21-18-49)45-40(51)44-34-13-14-36(32-6-4-3-5-31(32)34)54-38-15-16-41-39(46-38)43-28-7-12-33-27(23-28)25-42-47-33/h3-16,23-26H,17-22H2,1-2H3,(H,42,47)(H,41,43,46)(H2,44,45,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205296 (US9249125, 49) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1cccc(CN2CCCC2=O)c1 Show InChI InChI=1S/C40H38N10O3/c1-40(2,3)34-22-35(50(48-34)28-9-6-8-25(20-28)24-49-19-7-12-37(49)51)45-39(52)44-32-15-16-33(30-11-5-4-10-29(30)32)53-36-17-18-41-38(46-36)43-27-13-14-31-26(21-27)23-42-47-31/h4-6,8-11,13-18,20-23H,7,12,19,24H2,1-3H3,(H,42,47)(H,41,43,46)(H2,44,45,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205253 (US9249125, 4) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4n(C)cnc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H35N9O2/c1-23-10-13-25(14-11-23)46-33(21-32(44-46)37(2,3)4)42-36(47)41-28-15-17-31(27-9-7-6-8-26(27)28)48-34-18-19-38-35(43-34)40-24-12-16-30-29(20-24)39-22-45(30)5/h6-22H,1-5H3,(H,38,40,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205295 (US9249125, 48) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ccc5c4)n3)c3ccccc23)n(n1)-c1cccc(CN2CCCC2=O)c1 Show InChI InChI=1S/C41H39N9O3/c1-41(2,3)35-24-36(50(48-35)29-9-6-8-26(22-29)25-49-21-7-12-38(49)51)46-40(52)45-33-15-16-34(31-11-5-4-10-30(31)33)53-37-18-20-43-39(47-37)44-28-13-14-32-27(23-28)17-19-42-32/h4-6,8-11,13-20,22-24,42H,7,12,21,25H2,1-3H3,(H,43,44,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205262 (US9249125, 15) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)nc1 Show InChI InChI=1S/C40H41N11O4/c1-40(2,3)34-23-35(51(49-34)28-9-13-36(42-25-28)54-21-18-50-16-19-53-20-17-50)46-39(52)45-32-11-12-33(30-7-5-4-6-29(30)32)55-37-14-15-41-38(47-37)44-27-8-10-31-26(22-27)24-43-48-31/h4-15,22-25H,16-21H2,1-3H3,(H,43,48)(H,41,44,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205275 (US9249125, 28) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(Cl)c4[nH]ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H32ClN9O2/c1-21-9-11-24(12-10-21)46-31(19-30(45-46)36(2,3)4)42-35(47)41-28-13-14-29(26-8-6-5-7-25(26)28)48-32-15-16-38-34(43-32)40-23-17-22-20-39-44-33(22)27(37)18-23/h5-20H,1-4H3,(H,39,44)(H,38,40,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205289 (US9249125, 42) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C)c4[nH]ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H35N9O3/c1-22-18-24(19-23-21-39-44-34(22)23)40-35-38-17-16-33(43-35)49-30-15-14-29(27-8-6-7-9-28(27)30)41-36(47)42-32-20-31(37(2,3)4)45-46(32)25-10-12-26(48-5)13-11-25/h6-21H,1-5H3,(H,39,44)(H,38,40,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205308 (US9249125, 61) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CC(=O)Nc5c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C41H41N9O5/c1-26(2)34-25-37(50(48-34)29-9-11-30(12-10-29)54-22-19-49-17-20-53-21-18-49)46-41(52)45-33-13-14-36(32-6-4-3-5-31(32)33)55-39-15-16-42-40(47-39)43-28-8-7-27-23-38(51)44-35(27)24-28/h3-16,24-26H,17-23H2,1-2H3,(H,44,51)(H,42,43,47)(H2,45,46,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205261 (US9249125, 13) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C35H32N10O3/c1-35(2,3)29-18-30(45(44-29)23-10-14-31(47-4)37-20-23)41-34(46)40-27-12-13-28(25-8-6-5-7-24(25)27)48-32-15-16-36-33(42-32)39-22-9-11-26-21(17-22)19-38-43-26/h5-20H,1-4H3,(H,38,43)(H,36,39,42)(H2,40,41,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205340 (US9249125, 5) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4onc(N)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H33N9O3/c1-21-9-12-23(13-10-21)45-31(20-30(43-45)36(2,3)4)41-35(46)40-27-14-16-28(25-8-6-5-7-24(25)27)47-32-17-18-38-34(42-32)39-22-11-15-29-26(19-22)33(37)44-48-29/h5-20H,1-4H3,(H2,37,44)(H,38,39,42)(H2,40,41,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205329 (US9249125, 82) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ccc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H33N9O3/c1-36(2,3)30-20-31(45(44-30)24-10-14-32(47-4)39-21-24)42-35(46)41-28-12-13-29(26-8-6-5-7-25(26)28)48-33-16-18-38-34(43-33)40-23-9-11-27-22(19-23)15-17-37-27/h5-21,37H,1-4H3,(H,38,40,43)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205285 (US9249125, 38) Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ccc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H34N8O3/c1-37(2,3)32-22-33(45(44-32)25-10-12-26(47-4)13-11-25)42-36(46)41-30-15-16-31(28-8-6-5-7-27(28)30)48-34-18-20-39-35(43-34)40-24-9-14-29-23(21-24)17-19-38-29/h5-22,38H,1-4H3,(H,39,40,43)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205274 (US9249125, 27) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C)c4[nH]ncc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H35N9O2/c1-22-10-12-26(13-11-22)46-32(20-31(45-46)37(3,4)5)42-36(47)41-29-14-15-30(28-9-7-6-8-27(28)29)48-33-16-17-38-35(43-33)40-25-18-23(2)34-24(19-25)21-39-44-34/h6-21H,1-5H3,(H,39,44)(H,38,40,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205284 (US9249125, 37) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ccc5c4)n3)c3ccccc23)n(n1)-c1ccc(O)cc1 Show InChI InChI=1S/C36H32N8O3/c1-36(2,3)31-21-32(44(43-31)24-9-11-25(45)12-10-24)41-35(46)40-29-14-15-30(27-7-5-4-6-26(27)29)47-33-17-19-38-34(42-33)39-23-8-13-28-22(20-23)16-18-37-28/h4-21,37,45H,1-3H3,(H,38,39,42)(H2,40,41,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205279 (US9249125, 32) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cnc4[nH]ccc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H33N9O2/c1-22-9-11-25(12-10-22)45-31(20-30(44-45)36(2,3)4)42-35(46)41-28-13-14-29(27-8-6-5-7-26(27)28)47-32-16-18-38-34(43-32)40-24-19-23-15-17-37-33(23)39-21-24/h5-21H,1-4H3,(H,37,39)(H,38,40,43)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205341 (US9249125, 7) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(O)cc1 Show InChI InChI=1S/C35H31N9O3/c1-35(2,3)30-19-31(44(43-30)23-9-11-24(45)12-10-23)40-34(46)39-28-14-15-29(26-7-5-4-6-25(26)28)47-32-16-17-36-33(41-32)38-22-8-13-27-21(18-22)20-37-42-27/h4-20,45H,1-3H3,(H,37,42)(H,36,38,41)(H2,39,40,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205250 (US9249125, 1) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ccc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H34N8O2/c1-23-9-12-26(13-10-23)45-33(22-32(44-45)37(2,3)4)42-36(46)41-30-15-16-31(28-8-6-5-7-27(28)30)47-34-18-20-39-35(43-34)40-25-11-14-29-24(21-25)17-19-38-29/h5-22,38H,1-4H3,(H,39,40,43)(H2,41,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205278 (US9249125, 31) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4ncn(C)c4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C37H35N9O2/c1-23-10-13-25(14-11-23)46-33(21-32(44-46)37(2,3)4)42-36(47)41-28-16-17-31(27-9-7-6-8-26(27)28)48-34-18-19-38-35(43-34)40-24-12-15-29-30(20-24)45(5)22-39-29/h6-22H,1-5H3,(H,38,40,43)(H2,41,42,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205281 (US9249125, 34) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4scnc4c3)n2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C36H32N8O2S/c1-22-9-12-24(13-10-22)44-32(20-31(43-44)36(2,3)4)41-35(45)40-27-14-15-29(26-8-6-5-7-25(26)27)46-33-17-18-37-34(42-33)39-23-11-16-30-28(19-23)38-21-47-30/h5-21H,1-4H3,(H,37,39,42)(H2,40,41,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM205309 (US9249125, 62) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5c(NC(=O)C5(C)C)c4)n3)c3ccccc23)n(n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C44H47N9O5/c1-43(2,3)37-27-38(53(51-37)29-11-13-30(14-12-29)57-25-22-52-20-23-56-24-21-52)49-42(55)48-34-16-17-36(32-9-7-6-8-31(32)34)58-39-18-19-45-41(50-39)46-28-10-15-33-35(26-28)47-40(54)44(33,4)5/h6-19,26-27H,20-25H2,1-5H3,(H,47,54)(H,45,46,50)(H2,48,49,55)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...				US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG
					More data for this Ligand-Target Pair

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