Compile Data Set for Download or QSAR

Found 980 hits of ph data with Target = '11-beta-hydroxysteroid dehydrogenase 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99290 (US8497281, 135 | US8497281, 68 | US9120769, 68 | U...) Show SMILES Oc1ccc(cc1)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C20H21NO2/c22-16-10-7-15(8-11-16)20(23)21-13-3-6-18-17-5-2-1-4-14(17)9-12-19(18)21/h1-2,4-5,7-8,10-11,18-19,22H,3,6,9,12-13H2/t18?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99291 (US8497281, 69) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O/c25-21(15-7-9-18-19(12-15)23-13-22-18)24-11-3-6-17-16-5-2-1-4-14(16)8-10-20(17)24/h1-2,4-5,7,9,12-13,17,20H,3,6,8,10-11H2,(H,22,23)/t17?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99292 (US8497281, 70) Show SMILES O=C(N1CCC[C@@H]2[C@H]1CCc1ccccc21)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O/c25-21(15-7-9-18-19(12-15)23-13-22-18)24-11-3-6-17-16-5-2-1-4-14(16)8-10-20(17)24/h1-2,4-5,7,9,12-13,17,20H,3,6,8,10-11H2,(H,22,23)/t17-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99293 (US8497281, 71) Show SMILES O=C(N1CCCC2[C@H]1CCc1ccccc21)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O/c25-21(15-7-9-18-19(12-15)23-13-22-18)24-11-3-6-17-16-5-2-1-4-14(16)8-10-20(17)24/h1-2,4-5,7,9,12-13,17,20H,3,6,8,10-11H2,(H,22,23)/t17?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	573	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99294 (US8497281, 72 | US9120769, 5 | US9663470, 5) Show SMILES NC(=O)c1ccc(cc1)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C21H22N2O2/c22-20(24)15-7-9-16(10-8-15)21(25)23-13-3-6-18-17-5-2-1-4-14(17)11-12-19(18)23/h1-2,4-5,7-10,18-19H,3,6,11-13H2,(H2,22,24)/t18?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	861	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99295 (US8497281, 73) Show SMILES COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-21-6-2-4-15-16-5-3-11-25(20(16)10-8-17(15)21)22(26)14-7-9-18-19(12-14)24-13-23-18/h2,4,6-7,9,12-13,16,20H,3,5,8,10-11H2,1H3,(H,23,24)/t16?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	296	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99296 (US8497281, 74) Show SMILES Oc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-20-5-1-3-14-15-4-2-10-24(19(15)9-7-16(14)20)21(26)13-6-8-17-18(11-13)23-12-22-17/h1,3,5-6,8,11-12,15,19,25H,2,4,7,9-10H2,(H,22,23)/t15?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99297 (US8497281, 75) Show SMILES COc1cccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-20-6-2-4-14-8-10-19-16(21(14)20)5-3-11-25(19)22(26)15-7-9-17-18(12-15)24-13-23-17/h2,4,6-7,9,12-13,16,19H,3,5,8,10-11H2,1H3,(H,23,24)/t16?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	342	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99298 (US8497281, 76) Show SMILES COc1cccc2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-20-6-2-4-14-8-10-19-16(21(14)20)5-3-11-25(19)22(26)15-7-9-17-18(12-15)24-13-23-17/h2,4,6-7,9,12-13,16,19H,3,5,8,10-11H2,1H3,(H,23,24)/t16?,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	481	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99299 (US8497281, 77) Show SMILES C[C@]12CCCN([C@H]1CCc1ccccc21)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O/c1-22-11-4-12-25(20(22)10-8-15-5-2-3-6-17(15)22)21(26)16-7-9-18-19(13-16)24-14-23-18/h2-3,5-7,9,13-14,20H,4,8,10-12H2,1H3,(H,23,24)/t20-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	321	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99300 (US8497281, 78) Show SMILES C[C@]12CCCN([C@@H]1CCc1ccccc21)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O/c1-22-11-4-12-25(20(22)10-8-15-5-2-3-6-17(15)22)21(26)16-7-9-18-19(13-16)24-14-23-18/h2-3,5-7,9,13-14,20H,4,8,10-12H2,1H3,(H,23,24)/t20-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99301 (US8497281, 79) Show SMILES COc1cccc2C3CCCN([C@@H]3CCc12)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-21-6-2-4-15-16-5-3-11-25(20(16)10-8-17(15)21)22(26)14-7-9-18-19(12-14)24-13-23-18/h2,4,6-7,9,12-13,16,20H,3,5,8,10-11H2,1H3,(H,23,24)/t16?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	367	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99302 (US8497281, 80) Show SMILES Oc1cccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C21H21N3O2/c25-19-5-1-3-13-7-9-18-15(20(13)19)4-2-10-24(18)21(26)14-6-8-16-17(11-14)23-12-22-16/h1,3,5-6,8,11-12,15,18,25H,2,4,7,9-10H2,(H,22,23)/t15?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	257	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99303 (US8497281, 81) Show SMILES COc1ccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-16-7-4-14-6-9-21-17(18(14)12-16)3-2-10-25(21)22(26)15-5-8-19-20(11-15)24-13-23-19/h4-5,7-8,11-13,17,21H,2-3,6,9-10H2,1H3,(H,23,24)/t17?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	405	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99304 (US8497281, 82) Show SMILES COc1ccc2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-16-7-4-14-6-9-21-17(18(14)12-16)3-2-10-25(21)22(26)15-5-8-19-20(11-15)24-13-23-19/h4-5,7-8,11-13,17,21H,2-3,6,9-10H2,1H3,(H,23,24)/t17?,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99305 (US8497281, 83) Show SMILES Oc1ccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-15-6-3-13-5-8-20-16(17(13)11-15)2-1-9-24(20)21(26)14-4-7-18-19(10-14)23-12-22-18/h3-4,6-7,10-12,16,20,25H,1-2,5,8-9H2,(H,22,23)/t16?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99306 (US8497281, 17) Show SMILES Oc1ccc2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-15-6-3-13-5-8-20-16(17(13)11-15)2-1-9-24(20)21(26)14-4-7-18-19(10-14)23-12-22-18/h3-4,6-7,10-12,16,20,25H,1-2,5,8-9H2,(H,22,23)/t16?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99307 (US8497281, 85) Show SMILES Oc1cccc2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C21H21N3O2/c25-19-5-1-3-13-7-9-18-15(20(13)19)4-2-10-24(18)21(26)14-6-8-16-17(11-14)23-12-22-16/h1,3,5-6,8,11-12,15,18,25H,2,4,7,9-10H2,(H,22,23)/t15?,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99308 (US8497281, 19) Show SMILES Oc1cccc2C3CCCN([C@@H]3CCc12)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-20-5-1-3-14-15-4-2-10-24(19(15)9-7-16(14)20)21(26)13-6-8-17-18(11-13)23-12-22-17/h1,3,5-6,8,11-12,15,19,25H,2,4,7,9-10H2,(H,22,23)/t15?,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99309 (US8497281, 87) Show SMILES Fc1cc(F)c2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C21H19F2N3O/c22-13-9-16-14(17(23)10-13)4-6-20-15(16)2-1-7-26(20)21(27)12-3-5-18-19(8-12)25-11-24-18/h3,5,8-11,15,20H,1-2,4,6-7H2,(H,24,25)/t15?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	227	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99310 (US8497281, 88) Show SMILES Fc1cc(F)c2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c2c1 |r| Show InChI InChI=1S/C21H19F2N3O/c22-13-9-16-14(17(23)10-13)4-6-20-15(16)2-1-7-26(20)21(27)12-3-5-18-19(8-12)25-11-24-18/h3,5,8-11,15,20H,1-2,4,6-7H2,(H,24,25)/t15?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99311 (US8497281, 89) Show SMILES COc1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-16-6-7-17-14(11-16)5-9-21-18(17)3-2-10-25(21)22(26)15-4-8-19-20(12-15)24-13-23-19/h4,6-8,11-13,18,21H,2-3,5,9-10H2,1H3,(H,23,24)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99312 (US8497281, 90) Show SMILES COc1ccc2C3CCCN([C@@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c1-27-16-6-7-17-14(11-16)5-9-21-18(17)3-2-10-25(21)22(26)15-4-8-19-20(12-15)24-13-23-19/h4,6-8,11-13,18,21H,2-3,5,9-10H2,1H3,(H,23,24)/t18?,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	551	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99313 (US8497281, 24) Show SMILES Oc1ccc2C3CCCN([C@@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-15-5-6-16-13(10-15)4-8-20-17(16)2-1-9-24(20)21(26)14-3-7-18-19(11-14)23-12-22-18/h3,5-7,10-12,17,20,25H,1-2,4,8-9H2,(H,22,23)/t17?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99314 (US8497281, 92) Show SMILES Oc1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O2/c25-15-5-6-16-13(10-15)4-8-20-17(16)2-1-9-24(20)21(26)14-3-7-18-19(11-14)23-12-22-18/h3,5-7,10-12,17,20,25H,1-2,4,8-9H2,(H,22,23)/t17?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	475	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99315 (US8497281, 93) Show SMILES Fc1cccc2CC[C@@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C21H20FN3O/c22-16-5-1-3-13-7-9-19-15(20(13)16)4-2-10-25(19)21(26)14-6-8-17-18(11-14)24-12-23-17/h1,3,5-6,8,11-12,15,19H,2,4,7,9-10H2,(H,23,24)/t15?,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99316 (US8497281, 94) Show SMILES Fc1cccc2CC[C@H]3C(CCCN3C(=O)c3ccc4nc[nH]c4c3)c12 |r| Show InChI InChI=1S/C21H20FN3O/c22-16-5-1-3-13-7-9-19-15(20(13)16)4-2-10-25(19)21(26)14-6-8-17-18(11-14)24-12-23-17/h1,3,5-6,8,11-12,15,19H,2,4,7,9-10H2,(H,23,24)/t15?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	297	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99317 (US8497281, 28) Show SMILES O=C(N1CCCC2[C@H]1CCc1cc(ccc21)-c1ccccc1)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C27H25N3O/c31-27(21-9-12-24-25(16-21)29-17-28-24)30-14-4-7-23-22-11-8-19(18-5-2-1-3-6-18)15-20(22)10-13-26(23)30/h1-3,5-6,8-9,11-12,15-17,23,26H,4,7,10,13-14H2,(H,28,29)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99318 (US8497281, 96) Show SMILES O=C(N1CCCC2[C@@H]1CCc1cc(ccc21)-c1ccccc1)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C27H25N3O/c31-27(21-9-12-24-25(16-21)29-17-28-24)30-14-4-7-23-22-11-8-19(18-5-2-1-3-6-18)15-20(22)10-13-26(23)30/h1-3,5-6,8-9,11-12,15-17,23,26H,4,7,10,13-14H2,(H,28,29)/t23?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	831	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99319 (US8497281, 127 | US8497281, 30 | US9120769, 30 | U...) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2[nH]cnc2n1 |r| Show InChI InChI=1S/C20H20N4O/c25-20(17-9-8-16-19(23-17)22-12-21-16)24-11-3-6-15-14-5-2-1-4-13(14)7-10-18(15)24/h1-2,4-5,8-9,12,15,18H,3,6-7,10-11H2,(H,21,22,23)/t15?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99320 (US8497281, 98 | US9120769, 31 | US9663470, 31) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2nccn2c1 |r| Show InChI InChI=1S/C21H21N3O/c25-21(16-8-10-20-22-11-13-23(20)14-16)24-12-3-6-18-17-5-2-1-4-15(17)7-9-19(18)24/h1-2,4-5,8,10-11,13-14,18-19H,3,6-7,9,12H2/t18?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	469	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99321 (US8497281, 99 | US9120769, 32) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2[nH]c(=O)sc2c1 |r| Show InChI InChI=1S/C21H20N2O2S/c24-20(14-7-9-17-19(12-14)26-21(25)22-17)23-11-3-6-16-15-5-2-1-4-13(15)8-10-18(16)23/h1-2,4-5,7,9,12,16,18H,3,6,8,10-11H2,(H,22,25)/t16?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	954	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99322 (US8497281, 100) Show SMILES COC(=O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C23H23N3O3/c1-29-23(28)16-4-7-17-14(11-16)6-9-21-18(17)3-2-10-26(21)22(27)15-5-8-19-20(12-15)25-13-24-19/h4-5,7-8,11-13,18,21H,2-3,6,9-10H2,1H3,(H,24,25)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	676	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99323 (US8497281, 101) Show SMILES OCc1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H23N3O2/c26-12-14-3-6-17-15(10-14)5-8-21-18(17)2-1-9-25(21)22(27)16-4-7-19-20(11-16)24-13-23-19/h3-4,6-7,10-11,13,18,21,26H,1-2,5,8-9,12H2,(H,23,24)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	651	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99324 (US8497281, 35) Show SMILES OC(=O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H21N3O3/c26-21(14-4-7-18-19(11-14)24-12-23-18)25-9-1-2-17-16-6-3-15(22(27)28)10-13(16)5-8-20(17)25/h3-4,6-7,10-12,17,20H,1-2,5,8-9H2,(H,23,24)(H,27,28)/t17?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99325 (US8497281, 103) Show SMILES CNC(=O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-24-22(28)15-4-7-17-14(11-15)6-9-21-18(17)3-2-10-27(21)23(29)16-5-8-19-20(12-16)26-13-25-19/h4-5,7-8,11-13,18,21H,2-3,6,9-10H2,1H3,(H,24,28)(H,25,26)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99326 (US8497281, 104) Show SMILES NC(=O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H22N4O2/c23-21(27)14-3-6-16-13(10-14)5-8-20-17(16)2-1-9-26(20)22(28)15-4-7-18-19(11-15)25-12-24-18/h3-4,6-7,10-12,17,20H,1-2,5,8-9H2,(H2,23,27)(H,24,25)/t17?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99327 (US8497281, 105) Show SMILES CN(C)C(=O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C24H26N4O2/c1-27(2)23(29)16-5-8-18-15(12-16)7-10-22-19(18)4-3-11-28(22)24(30)17-6-9-20-21(13-17)26-14-25-20/h5-6,8-9,12-14,19,22H,3-4,7,10-11H2,1-2H3,(H,25,26)/t19?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99328 (US8497281, 106) Show SMILES O=C(N1CCCC1)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C26H28N4O2/c31-25(29-11-1-2-12-29)18-5-8-20-17(14-18)7-10-24-21(20)4-3-13-30(24)26(32)19-6-9-22-23(15-19)28-16-27-22/h5-6,8-9,14-16,21,24H,1-4,7,10-13H2,(H,27,28)/t21?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99329 (US8497281, 40) Show SMILES O=C(N1CCOCC1)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C26H28N4O3/c31-25(29-10-12-33-13-11-29)18-3-6-20-17(14-18)5-8-24-21(20)2-1-9-30(24)26(32)19-4-7-22-23(15-19)28-16-27-22/h3-4,6-7,14-16,21,24H,1-2,5,8-13H2,(H,27,28)/t21?,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99330 (US8497281, 108) Show SMILES CC(C)(O)c1ccc2C3CCCN([C@H]3CCc2c1)C(=O)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C24H27N3O2/c1-24(2,29)17-7-8-18-15(12-17)6-10-22-19(18)4-3-11-27(22)23(28)16-5-9-20-21(13-16)26-14-25-20/h5,7-9,12-14,19,22,29H,3-4,6,10-11H2,1-2H3,(H,25,26)/t19?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99331 (US8497281, 109) Show SMILES O=C(N1CCCC2[C@@H]1CCc1cc(ccc21)C#N)c1ccc2nc[nH]c2c1 |r| Show InChI InChI=1S/C22H20N4O/c23-12-14-3-6-17-15(10-14)5-8-21-18(17)2-1-9-26(21)22(27)16-4-7-19-20(11-16)25-13-24-19/h3-4,6-7,10-11,13,18,21H,1-2,5,8-9H2,(H,24,25)/t18?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	418	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99332 (US8497281, 110 | US9120769, 43 | US9663470, 43) Show SMILES Nc1nc2ccc(cc2s1)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C21H21N3OS/c22-21-23-17-9-7-14(12-19(17)26-21)20(25)24-11-3-6-16-15-5-2-1-4-13(15)8-10-18(16)24/h1-2,4-5,7,9,12,16,18H,3,6,8,10-11H2,(H2,22,23)/t16?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99333 (US8497281, 44 | US9120769, 44 | US9663470, 44) Show SMILES Cc1ccc(cc1O)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C21H23NO2/c1-14-8-9-16(13-20(14)23)21(24)22-12-4-7-18-17-6-3-2-5-15(17)10-11-19(18)22/h2-3,5-6,8-9,13,18-19,23H,4,7,10-12H2,1H3/t18?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99334 (US8497281, 112 | US9120769, 45 | US9663470, 45) Show SMILES COc1ccc(cc1N)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C21H24N2O2/c1-25-20-11-9-15(13-18(20)22)21(24)23-12-4-7-17-16-6-3-2-5-14(16)8-10-19(17)23/h2-3,5-6,9,11,13,17,19H,4,7-8,10,12,22H2,1H3/t17?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99335 (US8497281, 46 | US9120769, 46 | US9663470, 46) Show SMILES Cc1cc2cc(ccc2[nH]1)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C23H24N2O/c1-15-13-18-14-17(8-10-21(18)24-15)23(26)25-12-4-7-20-19-6-3-2-5-16(19)9-11-22(20)25/h2-3,5-6,8,10,13-14,20,22,24H,4,7,9,11-12H2,1H3/t20?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99336 (US8497281, 47 | US9120769, 47 | US9663470, 47) Show SMILES Cn1c2ccc(cc2[nH]c1=O)C(=O)N1CCCC2[C@@H]1CCc1ccccc21 |r| Show InChI InChI=1S/C22H23N3O2/c1-24-20-11-9-15(13-18(20)23-22(24)27)21(26)25-12-4-7-17-16-6-3-2-5-14(16)8-10-19(17)25/h2-3,5-6,9,11,13,17,19H,4,7-8,10,12H2,1H3,(H,23,27)/t17?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99337 (US8497281, 115 | US9120769, 48 | US9663470, 48) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2cc[nH]c2c1 |r| Show InChI InChI=1S/C22H22N2O/c25-22(17-8-7-16-11-12-23-20(16)14-17)24-13-3-6-19-18-5-2-1-4-15(18)9-10-21(19)24/h1-2,4-5,7-8,11-12,14,19,21,23H,3,6,9-10,13H2/t19?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	514	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99338 (US8497281, 116 | US9120769, 49 | US9663470, 49) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2NC(=O)Cc2c1 |r| Show InChI InChI=1S/C22H22N2O2/c25-21-13-16-12-15(7-9-19(16)23-21)22(26)24-11-3-6-18-17-5-2-1-4-14(17)8-10-20(18)24/h1-2,4-5,7,9,12,18,20H,3,6,8,10-11,13H2,(H,23,25)/t18?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99339 (US8497281, 50 | US9120769, 50 | US9663470, 50) Show SMILES O=C(N1CCCC2[C@@H]1CCc1ccccc21)c1ccc2CC(=O)Nc2c1 |r| Show InChI InChI=1S/C22H22N2O2/c25-21-13-15-7-8-16(12-19(15)23-21)22(26)24-11-3-6-18-17-5-2-1-4-14(17)9-10-20(18)24/h1-2,4-5,7-8,12,18,20H,3,6,9-11,13H2,(H,23,25)/t18?,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair

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