Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 2.40E+3 | -32.1 | n/a | n/a | n/a | n/a | n/a | 5.5 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0230 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Candida albicans) | BDBM18043 (1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2-F]QU...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 6.4 | 30 |
GSK | Assay Description IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh... | J Med Chem 44: 2928-32 (2001) Article DOI: 10.1021/jm0101444 BindingDB Entry DOI: 10.7270/Q2XW4H2K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Candida albicans) | BDBM18045 (5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE | 5-(phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | 6.4 | 30 |
GSK | Assay Description IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh... | J Med Chem 44: 2928-32 (2001) Article DOI: 10.1021/jm0101444 BindingDB Entry DOI: 10.7270/Q2XW4H2K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Candida albicans) | BDBM18046 (5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 6.4 | 30 |
GSK | Assay Description IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh... | J Med Chem 44: 2928-32 (2001) Article DOI: 10.1021/jm0101444 BindingDB Entry DOI: 10.7270/Q2XW4H2K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Candida albicans) | BDBM18047 (5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDI...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 6.4 | 30 |
GSK | Assay Description IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh... | J Med Chem 44: 2928-32 (2001) Article DOI: 10.1021/jm0101444 BindingDB Entry DOI: 10.7270/Q2XW4H2K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Candida albicans) | BDBM18048 (5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOL...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | 6.4 | 30 |
GSK | Assay Description IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh... | J Med Chem 44: 2928-32 (2001) Article DOI: 10.1021/jm0101444 BindingDB Entry DOI: 10.7270/Q2XW4H2K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038269 (2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038267 (2-Amino-6,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038268 (2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038273 (2-Amino-7,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038274 (2-Amino-6-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.08E+5 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038261 (2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038271 (2-Amino-8-ethyl-6-methyl-2,8-dihydro-3H-pyrido[2,3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 7.40E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038265 (2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038262 (2-Amino-5,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038275 (2-Amino-8-methyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038263 (2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038263 (2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038268 (2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 700 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038269 (2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038272 (2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038266 (2-Amino-8-isopropyl-2,8-dihydro-3H-pyrido[2,3-d]py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038269 (2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038274 (2-Amino-6-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038273 (2-Amino-7,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038270 (2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038272 (2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038270 (2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 600 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038271 (2-Amino-8-ethyl-6-methyl-2,8-dihydro-3H-pyrido[2,3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038266 (2-Amino-8-isopropyl-2,8-dihydro-3H-pyrido[2,3-d]py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038264 (2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038267 (2-Amino-6,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038260 (2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038264 (2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038265 (2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038270 (2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038260 (2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038264 (2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038265 (2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038263 (2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038262 (2-Amino-5,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038261 (2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038268 (2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038273 (2-Amino-7,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50038263 (2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | 6.6 | n/a |
University of Sydney Curated by ChEMBL | Assay Description Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPH | J Med Chem 37: 4211-21 (1995) BindingDB Entry DOI: 10.7270/Q2WW7GQH | |||||||||||
More data for this Ligand-Target Pair |
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