Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Falcipain-2 (Plasmodium falciparum) | BDBM12032 (1-{4-[(2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enoyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12034 (3-(4-chlorophenyl)-1-{4-[(2E)-3-(4-chlorophenyl)pr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12035 (3-(4-chlorophenyl)-1-{4-[(2E)-3-(2,4-dichloropheny...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12036 (3-(4-chlorophenyl)-1-{4-[(2E)-3-(2,4-difluoropheny...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12042 ((2R,3R)-3-{[(1S)-1-[(4-carbamimidamidobutyl)carbam...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12038 (3-(4-chlorophenyl)-1-{4-[(2E)-3-phenylprop-2-enoyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12039 (3-(4-chlorophenyl)-1-{4-[(2E)-3-(pyridin-3-yl)prop...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12040 (3-(4-methoxyphenyl)-1-{4-[(2E)-3-(pyridin-3-yl)pro...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12041 ((2S)-2-({5-[(diaminomethylidene)amino]-1-oxopentan...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Falcipain-2 (Plasmodium falciparum) | BDBM12037 (3-(4-chlorophenyl)-1-{4-[(2E)-3-(3,4,5-trimethoxyp...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 5.5 | 22 |
Universidad Central de Venezuela | Assay Description The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy... | J Med Chem 48: 3654-8 (2005) Article DOI: 10.1021/jm058208o BindingDB Entry DOI: 10.7270/Q2GF0RRD | |||||||||||
More data for this Ligand-Target Pair |