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Compile Data Set for Download or QSAR

Found 209 hits of ph data with Target = 'Glucagon receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))
BDBM123630
PNG
(US8748624, 144)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C29H21Cl2F4N3O3/c30-19-4-1-17(22(12-19)18-3-8-26(38-15-18)28(41)36-10-9-27(39)40)14-37-20-5-6-21(24(31)13-20)16-2-7-25(32)23(11-16)29(33,34)35/h1-8,11-13,15,37H,9-10,14H2,(H,36,41)(H,39,40)
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US Patent
12.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123549
PNG
(US8748624, 35)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)c(Cl)c1)C(F)(F)F
Show InChI InChI=1S/C29H21Cl2F4N3O3/c30-23-13-20(5-6-21(23)16-2-7-25(32)24(31)11-16)37-14-17-1-4-19(29(33,34)35)12-22(17)18-3-8-26(38-15-18)28(41)36-10-9-27(39)40/h1-8,11-13,15,37H,9-10,14H2,(H,36,41)(H,39,40)
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US Patent
14.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123582
PNG
(US8748624, 74)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(cc(Cl)c1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C29H21Cl3F3N3O3/c30-19-4-1-16(2-5-19)21-7-6-20(13-25(21)32)37-15-23-22(11-18(12-24(23)31)29(33,34)35)17-3-8-26(38-14-17)28(41)36-10-9-27(39)40/h1-8,11-14,37H,9-10,15H2,(H,36,41)(H,39,40)
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US Patent
14.9n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123633
PNG
(US8748624, 147)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(cc1)-c1ccc(cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H22Cl2F3N3O3/c30-21-6-1-18(24(14-21)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39)15-36-22-7-2-17(3-8-22)23-9-5-20(13-25(23)31)29(32,33)34/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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US Patent
15.7n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123637
PNG
(US8748624, 151)
Show SMILES Cc1cc(F)ccc1-c1ccc(NCc2ccc(Cl)cc2-c2ccc(nc2)C(=O)NCCC(O)=O)cc1
Show InChI InChI=1S/C29H25ClFN3O3/c1-18-14-23(31)7-10-25(18)19-3-8-24(9-4-19)33-16-20-2-6-22(30)15-26(20)21-5-11-27(34-17-21)29(37)32-13-12-28(35)36/h2-11,14-15,17,33H,12-13,16H2,1H3,(H,32,37)(H,35,36)
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US Patent
16.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123556
PNG
(US8748624, 42)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(cc1Cl)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H21Cl2F6N3O3/c31-24-12-19(30(36,37)38)4-6-21(24)22-7-5-20(13-25(22)32)40-14-16-1-3-18(29(33,34)35)11-23(16)17-2-8-26(41-15-17)28(44)39-10-9-27(42)43/h1-8,11-13,15,40H,9-10,14H2,(H,39,44)(H,42,43)
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US Patent
16.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123559
PNG
(US8748624, 51)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H21Cl4N3O3/c29-18-3-1-16(23(11-18)17-2-8-26(35-15-17)28(38)33-10-9-27(36)37)14-34-20-5-7-22(25(32)13-20)21-6-4-19(30)12-24(21)31/h1-8,11-13,15,34H,9-10,14H2,(H,33,38)(H,36,37)
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US Patent
16.8n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123557
PNG
(US8748624, 43)
Show SMILES Cc1cc(ccc1-c1ccc(NCc2ccc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C31H24ClF6N3O3/c1-17-12-20(30(33,34)35)5-7-23(17)24-8-6-22(14-26(24)32)40-15-18-2-4-21(31(36,37)38)13-25(18)19-3-9-27(41-16-19)29(44)39-11-10-28(42)43/h2-9,12-14,16,40H,10-11,15H2,1H3,(H,39,44)(H,42,43)
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US Patent
17.2n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123651
PNG
(US8748624, 174)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(F)cc1)C1=CCCCC1 |t:39|
Show InChI InChI=1S/C34H32FN3O3/c35-29-13-8-24(9-14-29)25-10-15-30(16-11-25)37-21-27-7-6-26(23-4-2-1-3-5-23)20-31(27)28-12-17-32(38-22-28)34(41)36-19-18-33(39)40/h4,6-17,20,22,37H,1-3,5,18-19,21H2,(H,36,41)(H,39,40)
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US Patent
18.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123558
PNG
(US8748624, 44)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C29H23ClF3N3O3/c30-23-8-2-18(3-9-23)19-4-10-24(11-5-19)35-16-20-1-7-22(29(31,32)33)15-25(20)21-6-12-26(36-17-21)28(39)34-14-13-27(37)38/h1-12,15,17,35H,13-14,16H2,(H,34,39)(H,37,38)
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US Patent
18.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123634
PNG
(US8748624, 148)
Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2ccc(Cl)cc2-c2ccc(nc2)C(=O)NCCC(O)=O)cc1
Show InChI InChI=1S/C29H25Cl2N3O3/c1-18-14-22(30)7-10-25(18)19-3-8-24(9-4-19)33-16-20-2-6-23(31)15-26(20)21-5-11-27(34-17-21)29(37)32-13-12-28(35)36/h2-11,14-15,17,33H,12-13,16H2,1H3,(H,32,37)(H,35,36)
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18.7n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123575
PNG
(US8748624, 67)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(cc(Cl)c1CNc1ccc(cc1)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C29H22Cl2F3N3O3/c30-21-6-1-17(2-7-21)18-3-8-22(9-4-18)36-16-24-23(13-20(14-25(24)31)29(32,33)34)19-5-10-26(37-15-19)28(40)35-12-11-27(38)39/h1-10,13-15,36H,11-12,16H2,(H,35,40)(H,38,39)
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US Patent
18.8n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123544
PNG
(US8748624, 30)
Show SMILES Cc1cc(ccc1-c1ccc(NCc2ccc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C31H25F6N3O3/c1-18-14-22(30(32,33)34)7-10-25(18)19-3-8-24(9-4-19)39-16-20-2-6-23(31(35,36)37)15-26(20)21-5-11-27(40-17-21)29(43)38-13-12-28(41)42/h2-11,14-15,17,39H,12-13,16H2,1H3,(H,38,43)(H,41,42)
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US Patent
19.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123535
PNG
(US8748624, 21)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H22Cl2F3N3O3/c30-21-6-9-23(25(31)14-21)17-2-7-22(8-3-17)36-15-18-1-5-20(29(32,33)34)13-24(18)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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US Patent
19.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123593
PNG
(US8748624, 92)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(F)c1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H21Cl3FN3O3/c29-18-3-1-16(23(11-18)17-2-8-26(35-15-17)28(38)33-10-9-27(36)37)14-34-20-5-7-22(25(32)13-20)21-6-4-19(30)12-24(21)31/h1-8,11-13,15,34H,9-10,14H2,(H,33,38)(H,36,37)
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US Patent
19.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123581
PNG
(US8748624, 73)
Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2c(Cl)cc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-21(31)5-8-23(17)18-2-6-22(7-3-18)37-16-25-24(13-20(14-26(25)32)30(33,34)35)19-4-9-27(38-15-19)29(41)36-11-10-28(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)
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US Patent
19.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123560
PNG
(US8748624, 52)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H22Cl2FN3O3/c29-20-5-1-18(15-33-22-8-9-23(25(30)14-22)17-2-6-21(31)7-3-17)24(13-20)19-4-10-26(34-16-19)28(37)32-12-11-27(35)36/h1-10,13-14,16,33H,11-12,15H2,(H,32,37)(H,35,36)
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US Patent
19.9n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123644
PNG
(US8748624, 158)
Show SMILES CC(C)c1ccc(CNc2ccc(cc2)-c2ccc(F)cc2)c(c1)-c1ccc(nc1)C(=O)NCCC(O)=O
Show InChI InChI=1S/C31H30FN3O3/c1-20(2)23-3-4-24(18-34-27-12-7-22(8-13-27)21-5-10-26(32)11-6-21)28(17-23)25-9-14-29(35-19-25)31(38)33-16-15-30(36)37/h3-14,17,19-20,34H,15-16,18H2,1-2H3,(H,33,38)(H,36,37)
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US Patent
20n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123580
PNG
(US8748624, 72)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(cc(Cl)c1CNc1ccc(cc1)-c1ccc(Cl)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H21Cl3F3N3O3/c30-19-4-7-21(25(32)13-19)16-1-5-20(6-2-16)37-15-23-22(11-18(12-24(23)31)29(33,34)35)17-3-8-26(38-14-17)28(41)36-10-9-27(39)40/h1-8,11-14,37H,9-10,15H2,(H,36,41)(H,39,40)
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US Patent
20.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123555
PNG
(US8748624, 41)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1cccc(c1Cl)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H22ClF6N3O3/c31-27-22(2-1-3-24(27)30(35,36)37)17-5-9-21(10-6-17)39-15-18-4-8-20(29(32,33)34)14-23(18)19-7-11-25(40-16-19)28(43)38-13-12-26(41)42/h1-11,14,16,39H,12-13,15H2,(H,38,43)(H,41,42)
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US Patent
20.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123647
PNG
(US8748624, 170)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C29H22Cl2F3N3O3/c30-21-6-4-18(24(13-21)19-5-9-26(37-16-19)28(40)35-11-10-27(38)39)15-36-22-7-8-23(25(31)14-22)17-2-1-3-20(12-17)29(32,33)34/h1-9,12-14,16,36H,10-11,15H2,(H,35,40)(H,38,39)
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US Patent
20.7n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123599
PNG
(US8748624, 102)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C29H20ClF6N3O3/c30-22-11-18(3-4-19(22)15-1-5-23(31)21(9-15)29(34,35)36)38-14-17-10-24(32)25(33)12-20(17)16-2-6-26(39-13-16)28(42)37-8-7-27(40)41/h1-6,9-13,38H,7-8,14H2,(H,37,42)(H,40,41)
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US Patent
21.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123547
PNG
(US8748624, 33)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H21Cl2F4N3O3/c30-24-12-19(32)4-6-21(24)22-7-5-20(13-25(22)31)37-14-16-1-3-18(29(33,34)35)11-23(16)17-2-8-26(38-15-17)28(41)36-10-9-27(39)40/h1-8,11-13,15,37H,9-10,14H2,(H,36,41)(H,39,40)
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US Patent
21.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123541
PNG
(US8748624, 27)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H21Cl3F3N3O3/c30-19-4-6-21(24(31)12-19)22-7-5-20(13-25(22)32)37-14-16-1-3-18(29(33,34)35)11-23(16)17-2-8-26(38-15-17)28(41)36-10-9-27(39)40/h1-8,11-13,15,37H,9-10,14H2,(H,36,41)(H,39,40)
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US Patent
21.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123626
PNG
(US8748624, 140)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C29H22Cl2F3N3O4/c30-20-5-1-18(24(13-20)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39)15-36-21-6-9-23(25(31)14-21)17-2-7-22(8-3-17)41-29(32,33)34/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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US Patent
21.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123545
PNG
(US8748624, 31)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H21ClF7N3O3/c31-24-13-20(5-6-21(24)16-2-7-25(32)23(11-16)30(36,37)38)40-14-17-1-4-19(29(33,34)35)12-22(17)18-3-8-26(41-15-18)28(44)39-10-9-27(42)43/h1-8,11-13,15,40H,9-10,14H2,(H,39,44)(H,42,43)
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US Patent
22.1n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123522
PNG
(US8748624, 7)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H22Cl3N3O3/c29-20-5-1-18(15-33-22-7-2-17(3-8-22)23-9-6-21(30)14-25(23)31)24(13-20)19-4-10-26(34-16-19)28(37)32-12-11-27(35)36/h1-10,13-14,16,33H,11-12,15H2,(H,32,37)(H,35,36)
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22.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123552
PNG
(US8748624, 38)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1cccc(c1Cl)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H21Cl2F6N3O3/c31-24-13-19(7-8-20(24)21-2-1-3-23(27(21)32)30(36,37)38)40-14-16-4-6-18(29(33,34)35)12-22(16)17-5-9-25(41-15-17)28(44)39-11-10-26(42)43/h1-9,12-13,15,40H,10-11,14H2,(H,39,44)(H,42,43)
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US Patent
22.5n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123571
PNG
(US8748624, 63)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1ccc(F)cc1F
Show InChI InChI=1S/C28H21Cl2F2N3O3/c29-18-3-1-16(23(11-18)17-2-8-26(35-15-17)28(38)33-10-9-27(36)37)14-34-20-5-7-21(24(30)13-20)22-6-4-19(31)12-25(22)32/h1-8,11-13,15,34H,9-10,14H2,(H,33,38)(H,36,37)
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US Patent
22.6n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123600
PNG
(US8748624, 103)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H21Cl2F2N3O3/c29-19-4-1-16(2-5-19)21-7-6-20(12-23(21)30)34-15-18-11-24(31)25(32)13-22(18)17-3-8-26(35-14-17)28(38)33-10-9-27(36)37/h1-8,11-14,34H,9-10,15H2,(H,33,38)(H,36,37)
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22.9n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123551
PNG
(US8748624, 37)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1F)C(F)(F)F
Show InChI InChI=1S/C29H21Cl2F4N3O3/c30-19-4-6-22(25(32)12-19)21-7-5-20(13-24(21)31)37-14-16-1-3-18(29(33,34)35)11-23(16)17-2-8-26(38-15-17)28(41)36-10-9-27(39)40/h1-8,11-13,15,37H,9-10,14H2,(H,36,41)(H,39,40)
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US Patent
23.2n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123604
PNG
(US8748624, 107)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1cccc(c1Cl)C(F)(F)F
Show InChI InChI=1S/C29H20Cl2F5N3O3/c30-22-11-17(5-6-18(22)19-2-1-3-21(27(19)31)29(34,35)36)38-14-16-10-23(32)24(33)12-20(16)15-4-7-25(39-13-15)28(42)37-9-8-26(40)41/h1-7,10-13,38H,8-9,14H2,(H,37,42)(H,40,41)
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23.7n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123548
PNG
(US8748624, 34)
Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2ccc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1Cl
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-21(31)5-7-23(17)24-8-6-22(14-26(24)32)37-15-18-2-4-20(30(33,34)35)13-25(18)19-3-9-27(38-16-19)29(41)36-11-10-28(39)40/h2-9,12-14,16,37H,10-11,15H2,1H3,(H,36,41)(H,39,40)
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US Patent
23.8n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123605
PNG
(US8748624, 108)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H20Cl3F2N3O3/c29-17-2-4-19(22(30)10-17)20-5-3-18(11-23(20)31)35-14-16-9-24(32)25(33)12-21(16)15-1-6-26(36-13-15)28(39)34-8-7-27(37)38/h1-6,9-13,35H,7-8,14H2,(H,34,39)(H,37,38)
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US Patent
23.9n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123585
PNG
(US8748624, 78)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(c(Cl)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C29H21Cl3F3N3O3/c30-19-4-1-16(2-5-19)21-7-6-20(12-24(21)31)37-15-18-11-25(32)23(29(33,34)35)13-22(18)17-3-8-26(38-14-17)28(41)36-10-9-27(39)40/h1-8,11-14,37H,9-10,15H2,(H,36,41)(H,39,40)
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24n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123586
PNG
(US8748624, 79)
Show SMILES Cc1cc(NCc2cc(Cl)c(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)ccc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-22(7-8-23(17)18-2-5-21(31)6-3-18)37-16-20-13-26(32)25(30(33,34)35)14-24(20)19-4-9-27(38-15-19)29(41)36-11-10-28(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)
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24n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123652
PNG
(US8748624, 175)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(F)cc1)C1CCCCC1
Show InChI InChI=1S/C34H34FN3O3/c35-29-13-8-24(9-14-29)25-10-15-30(16-11-25)37-21-27-7-6-26(23-4-2-1-3-5-23)20-31(27)28-12-17-32(38-22-28)34(41)36-19-18-33(39)40/h6-17,20,22-23,37H,1-5,18-19,21H2,(H,36,41)(H,39,40)
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24.2n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123584
PNG
(US8748624, 77)
Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2cc(Cl)c(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-21(31)5-8-23(17)18-2-6-22(7-3-18)37-16-20-13-26(32)25(30(33,34)35)14-24(20)19-4-9-27(38-15-19)29(41)36-11-10-28(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)
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24.2n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123546
PNG
(US8748624, 32)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)c(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H21Cl2F6N3O3/c31-24-7-2-16(11-23(24)30(36,37)38)21-6-5-20(13-25(21)32)40-14-17-1-4-19(29(33,34)35)12-22(17)18-3-8-26(41-15-18)28(44)39-10-9-27(42)43/h1-8,11-13,15,40H,9-10,14H2,(H,39,44)(H,42,43)
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US Patent
25.1n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123536
PNG
(US8748624, 22)
Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2ccc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1
Show InChI InChI=1S/C30H25ClF3N3O3/c1-18-14-23(31)7-10-25(18)19-3-8-24(9-4-19)36-16-20-2-6-22(30(32,33)34)15-26(20)21-5-11-27(37-17-21)29(40)35-13-12-28(38)39/h2-11,14-15,17,36H,12-13,16H2,1H3,(H,35,40)(H,38,39)
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US Patent
25.2n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123601
PNG
(US8748624, 104)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1F
Show InChI InChI=1S/C28H20Cl2F3N3O3/c29-17-2-4-20(23(31)10-17)19-5-3-18(11-22(19)30)35-14-16-9-24(32)25(33)12-21(16)15-1-6-26(36-13-15)28(39)34-8-7-27(37)38/h1-6,9-13,35H,7-8,14H2,(H,34,39)(H,37,38)
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US Patent
25.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123603
PNG
(US8748624, 106)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C29H20Cl2F5N3O3/c30-22-5-1-15(9-21(22)29(34,35)36)19-4-3-18(11-23(19)31)38-14-17-10-24(32)25(33)12-20(17)16-2-6-26(39-13-16)28(42)37-8-7-27(40)41/h1-6,9-13,38H,7-8,14H2,(H,37,42)(H,40,41)
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US Patent
26.1n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123537
PNG
(US8748624, 23)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(F)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C29H22ClF4N3O3/c30-25-14-21(31)6-9-23(25)17-2-7-22(8-3-17)36-15-18-1-5-20(29(32,33)34)13-24(18)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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26.1n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123554
PNG
(US8748624, 40)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1F)C(F)(F)F
Show InChI InChI=1S/C29H22ClF4N3O3/c30-21-6-9-23(25(31)14-21)17-2-7-22(8-3-17)36-15-18-1-5-20(29(32,33)34)13-24(18)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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US Patent
26.3n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123553
PNG
(US8748624, 39)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(c(F)c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C30H21ClF7N3O3/c31-24-13-20(5-6-21(24)16-2-7-23(25(32)11-16)30(36,37)38)40-14-17-1-4-19(29(33,34)35)12-22(17)18-3-8-26(41-15-18)28(44)39-10-9-27(42)43/h1-8,11-13,15,40H,9-10,14H2,(H,39,44)(H,42,43)
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US Patent
26.6n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123649
PNG
(US8748624, 172)
Show SMILES Cc1ccc(cc1)-c1ccc(NCc2ccc(Cl)cc2-c2ccc(nc2)C(=O)NCCC(O)=O)cc1Cl
Show InChI InChI=1S/C29H25Cl2N3O3/c1-18-2-4-19(5-3-18)24-10-9-23(15-26(24)31)33-16-20-6-8-22(30)14-25(20)21-7-11-27(34-17-21)29(37)32-13-12-28(35)36/h2-11,14-15,17,33H,12-13,16H2,1H3,(H,32,37)(H,35,36)
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26.9n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123650
PNG
(US8748624, 173)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C34H27Cl2N3O3/c35-27-11-14-29(31(36)19-27)23-8-12-28(13-9-23)38-20-25-7-6-24(22-4-2-1-3-5-22)18-30(25)26-10-15-32(39-21-26)34(42)37-17-16-33(40)41/h1-15,18-19,21,38H,16-17,20H2,(H,37,42)(H,40,41)
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27n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123636
PNG
(US8748624, 150)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(cc1)-c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C28H22Cl2FN3O3/c29-21-6-1-19(15-33-22-7-2-17(3-8-22)18-4-9-25(31)24(30)13-18)23(14-21)20-5-10-26(34-16-20)28(37)32-12-11-27(35)36/h1-10,13-14,16,33H,11-12,15H2,(H,32,37)(H,35,36)
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US Patent
27.7n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123583
PNG
(US8748624, 75)
Show SMILES Cc1cc(NCc2c(Cl)cc(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)ccc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-22(7-8-23(17)18-2-5-21(31)6-3-18)37-16-25-24(13-20(14-26(25)32)30(33,34)35)19-4-9-27(38-15-19)29(41)36-11-10-28(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)
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27.8n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM123542
PNG
(US8748624, 28)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C29H22Cl2F3N3O3/c30-21-6-2-17(3-7-21)23-9-8-22(14-25(23)31)36-15-18-1-5-20(29(32,33)34)13-24(18)19-4-10-26(37-16-19)28(40)35-12-11-27(38)39/h1-10,13-14,16,36H,11-12,15H2,(H,35,40)(H,38,39)
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28n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair
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