Compile Data Set for Download or QSAR

Found 324 hits of ph data with Target = 'Hepatocyte growth factor receptor'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM103457 (US8551989, 2) Show SMILES CC1=NC(C)=C(C#N)C(C1C#N)c1ccc2[nH]nc(SCc3ccccc3)c2c1 |t:1,4| Show InChI InChI=1S/C23H19N5S/c1-14-19(11-24)22(20(12-25)15(2)26-14)17-8-9-21-18(10-17)23(28-27-21)29-13-16-6-4-3-5-7-16/h3-10,19,22H,13H2,1-2H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out) using c-Met receptor.				US Patent US8551989 (2013) BindingDB Entry DOI: 10.7270/Q24F1PCX
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM240742 (US9422263, 43 | US9422263, 44) Show SMILES CN1C(C)=C(C#N)C(C(C#N)=C1C(F)(F)F)c1ccc2[nH]nc(C)c2c1 |c:10,t:3| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	32
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9422263 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZW2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM103459 (US8551989, 12) Show SMILES CCCS(=O)(=O)Nc1n[nH]c2ccc(cc12)C1C(C#N)C(C)=NC(C)=C1C#N |c:23,26| Show InChI InChI=1S/C19H20N6O2S/c1-4-7-28(26,27)25-19-14-8-13(5-6-17(14)23-24-19)18-15(9-20)11(2)22-12(3)16(18)10-21/h5-6,8,15,18H,4,7H2,1-3H3,(H2,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	475	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out) using c-Met receptor.				US Patent US8551989 (2013) BindingDB Entry DOI: 10.7270/Q24F1PCX
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM103460 (US8551989, 13) Show SMILES COc1n[nH]c2ccc(cc12)C1C(C#N)C(C)=NC(C)=C1C#N |c:18,21| Show InChI InChI=1S/C17H15N5O/c1-9-13(7-18)16(14(8-19)10(2)20-9)11-4-5-15-12(6-11)17(23-3)22-21-15/h4-6,13,16H,1-3H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out) using c-Met receptor.				US Patent US8551989 (2013) BindingDB Entry DOI: 10.7270/Q24F1PCX
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM103463 (US8551989, 24) Show SMILES CC(C)OCCOc1n[nH]c2ccc(cc12)C1C(C#N)C(=NC(C(F)F)=C1C#N)C(F)F |c:22,27| Show InChI InChI=1S/C21H19F4N5O2/c1-10(2)31-5-6-32-21-12-7-11(3-4-15(12)29-30-21)16-13(8-26)17(19(22)23)28-18(20(24)25)14(16)9-27/h3-4,7,10,13,16,19-20H,5-6H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out) using c-Met receptor.				US Patent US8551989 (2013) BindingDB Entry DOI: 10.7270/Q24F1PCX
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM103464 (US8551989, 25) Show SMILES COCCN(C)c1n[nH]c2ccc(cc12)C1C(C#N)C(C)=NC(C)=C1C#N |c:22,25| Show InChI InChI=1S/C20H22N6O/c1-12-16(10-21)19(17(11-22)13(2)23-12)14-5-6-18-15(9-14)20(25-24-18)26(3)7-8-27-4/h5-6,9,16,19H,7-8H2,1-4H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out) using c-Met receptor.				US Patent US8551989 (2013) BindingDB Entry DOI: 10.7270/Q24F1PCX
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109200 (US8604028, 56) Show SMILES CC1=NC(C)=C([N+]#[C-])C(C1C#N)c1cc2c(N)nccc2o1 |t:1,4| Show InChI InChI=1S/C16H13N5O/c1-8-11(7-17)14(15(19-3)9(2)21-8)13-6-10-12(22-13)4-5-20-16(10)18/h4-6,11,14H,1-2H3,(H2,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109201 (US8604028, 57) Show SMILES CC1=NC(C(F)F)=C(C#N)C(C1[N+]#[C-])c1cc2c(N)nccc2o1 |t:1,6| Show InChI InChI=1S/C16H11F2N5O/c1-7-13(21-2)12(9(6-19)14(23-7)15(17)18)11-5-8-10(24-11)3-4-22-16(8)20/h3-5,12-13,15H,1H3,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109202 (US8604028, 61) Show SMILES CC1=NC(=C([N+]#[C-])C(C1C#N)c1cc2c(N)nccc2o1)c1ccc(Cl)cc1 |t:1,3| Show InChI InChI=1S/C21H14ClN5O/c1-11-15(10-23)18(17-9-14-16(28-17)7-8-26-21(14)24)20(25-2)19(27-11)12-3-5-13(22)6-4-12/h3-9,15,18H,1H3,(H2,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109203 (US8604028, 65) Show SMILES CC1=NC2=C(C(C1[N+]#[C-])c1cc3c(NC(=O)c4ccccc4)nccc3o1)C(=O)OC2 |c:3,t:1| Show InChI InChI=1S/C23H16N4O4/c1-12-20(24-2)19(18-15(26-12)11-30-23(18)29)17-10-14-16(31-17)8-9-25-21(14)27-22(28)13-6-4-3-5-7-13/h3-10,19-20H,11H2,1H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109204 (US8604028, 70) Show SMILES CC1=C(C#N)[C@@H](c2cc3c(N)nccc3o2)C([N+]#[C-])=C2COCCN12 |r,c:1,t:20| Show InChI InChI=1S/C18H15N5O2/c1-10-12(8-19)16(17(21-2)13-9-24-6-5-23(10)13)15-7-11-14(25-15)3-4-22-18(11)20/h3-4,7,16H,5-6,9H2,1H3,(H2,20,22)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	610	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109205 (US8604028, 72) Show SMILES Nc1nccc2oc(cc12)[C@@H]1C2C(=O)OCC2=NC(=C1[N+]#[C-])c1ccc(Cl)cc1 |r,c:19,21| Show InChI InChI=1S/C21H13ClN4O3/c1-24-19-17(15-8-12-14(29-15)6-7-25-20(12)23)16-13(9-28-21(16)27)26-18(19)10-2-4-11(22)5-3-10/h2-8,16-17H,9H2,(H2,23,25)/t16?,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120815 ((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCCC1 |w:14.14| Show InChI InChI=1S/C35H33F4N5O4/c1-22-25(34(45)44(42-22)29-9-4-3-8-26(29)35(37,38)39)21-41-23-10-11-31(27(36)18-23)48-30-12-13-40-28-20-33(32(46-2)19-24(28)30)47-17-7-16-43-14-5-6-15-43/h3-4,8-13,18-21,42H,5-7,14-17H2,1-2H3/b41-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.04	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120816 ((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopro...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCOCC1 |w:14.14| Show InChI InChI=1S/C35H33F4N5O5/c1-22-25(34(45)44(42-22)29-7-4-3-6-26(29)35(37,38)39)21-41-23-8-9-31(27(36)18-23)49-30-10-11-40-28-20-33(32(46-2)19-24(28)30)48-15-5-12-43-13-16-47-17-14-43/h3-4,6-11,18-21,42H,5,12-17H2,1-2H3/b41-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120817 ((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(piperidin-1-...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCCCC1 |w:14.14| Show InChI InChI=1S/C36H35F4N5O4/c1-23-26(35(46)45(43-23)30-10-5-4-9-27(30)36(38,39)40)22-42-24-11-12-32(28(37)19-24)49-31-13-14-41-29-21-34(33(47-2)20-25(29)31)48-18-8-17-44-15-6-3-7-16-44/h4-5,9-14,19-22,43H,3,6-8,15-18H2,1-2H3/b42-22+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.63	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120818 ((E)-5-(((3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(O)n(-c4ccccc4C(F)(F)F)c(=O)n3C)ccnc2cc1OCCCN1CCCC1 |w:14.14,(-7.96,1.65,;-6.63,2.42,;-5.29,1.65,;-3.96,2.42,;-2.63,1.65,;-1.29,2.42,;-1.29,3.96,;.04,4.73,;1.37,3.96,;2.71,4.73,;2.71,6.27,;1.37,7.04,;.04,6.27,;-1.29,7.04,;4.04,7.04,;5.38,6.27,;6.71,7.04,;6.87,8.57,;5.73,9.6,;8.38,8.89,;9,10.3,;10.53,10.46,;11.16,11.87,;10.26,13.11,;8.72,12.95,;8.1,11.54,;6.57,11.38,;5.23,10.61,;6.09,12.85,;7.04,9.92,;9.15,7.56,;10.68,7.4,;8.12,6.41,;8.44,4.91,;.04,1.65,;.04,.11,;-1.29,-.66,;-2.63,.11,;-3.96,-.66,;-5.29,.11,;-6.63,-.66,;-7.96,.11,;-9.29,-.66,;-10.63,.11,;-11.96,-.66,;-13.37,-.03,;-14.4,-1.18,;-13.63,-2.51,;-12.12,-2.19,)| Show InChI InChI=1S/C35H33F4N5O5/c1-42-28(33(45)44(34(42)46)27-9-4-3-8-24(27)35(37,38)39)21-41-22-10-11-30(25(36)18-22)49-29-12-13-40-26-20-32(31(47-2)19-23(26)29)48-17-7-16-43-14-5-6-15-43/h3-4,8-13,18-21,45H,5-7,14-17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM120819 ((E)-5-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopro...) Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(O)n(-c4ccccc4F)c(=O)n3C)ccnc2cc1OCCCN1CCOCC1 |w:14.14,(-7.96,1.65,;-6.63,2.42,;-5.29,1.65,;-3.96,2.42,;-2.63,1.65,;-1.29,2.42,;-1.29,3.96,;.04,4.73,;1.37,3.96,;2.71,4.73,;2.71,6.27,;1.37,7.04,;.04,6.27,;-1.29,7.04,;4.04,7.04,;5.38,6.27,;6.71,7.04,;6.87,8.57,;5.73,9.6,;8.38,8.89,;9,10.3,;10.53,10.46,;11.16,11.87,;10.26,13.11,;8.72,12.95,;8.1,11.54,;6.57,11.38,;9.15,7.56,;10.68,7.4,;8.12,6.41,;8.44,4.91,;.04,1.65,;.04,.11,;-1.29,-.66,;-2.63,.11,;-3.96,-.66,;-5.29,.11,;-6.63,-.66,;-7.96,.11,;-9.29,-.66,;-10.63,.11,;-11.96,-.66,;-13.3,.11,;-14.63,-.66,;-14.63,-2.2,;-13.3,-2.97,;-11.96,-2.2,)| Show InChI InChI=1S/C34H33F2N5O6/c1-39-28(33(42)41(34(39)43)27-7-4-3-6-24(27)35)21-38-22-8-9-30(25(36)18-22)47-29-10-11-37-26-20-32(31(44-2)19-23(26)29)46-15-5-12-40-13-16-45-17-14-40/h3-4,6-11,18-21,42H,5,12-17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.78	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.89	n/a	n/a	n/a	n/a	7.0	25
Shenyang Pharmaceutical University, Ministry of Education					Assay Description The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...				Bioorg Chem 57: 30-42 (2014) Article DOI: 10.1016/j.bioorg.2014.07.011 BindingDB Entry DOI: 10.7270/Q2BG2MPQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124886 (US8759341, 2) Show SMILES Cc1[nH]nc2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)OC2 |c:17,19| Show InChI InChI=1S/C17H14N4O2/c1-8-11-6-10(4-5-12(11)21-20-8)14-15-13(7-23-17(15)22)19-9(2)16(14)18-3/h4-6,14,16H,7H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124888 (US8759341, 8) Show SMILES Cc1[nH]nc2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)NC2 |c:17,19| Show InChI InChI=1S/C17H15N5O/c1-8-11-6-10(4-5-12(11)22-21-8)14-15-13(7-19-17(15)23)20-9(2)16(14)18-3/h4-6,14,16H,7H2,1-2H3,(H,19,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124890 (US8759341, 18) Show SMILES Cc1n[nH]c2ccc(cc12)C1C2=C(COC2=O)N2CCOCC2=C1[N+]#[C-] |c:26,t:13| Show InChI InChI=1S/C19H16N4O3/c1-10-12-7-11(3-4-13(12)22-21-10)16-17-14(9-26-19(17)24)23-5-6-25-8-15(23)18(16)20-2/h3-4,7,16H,5-6,8-9H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124891 (US8759341, 22) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)OC2 |c:27,29| Show InChI InChI=1S/C24H21N5O3/c1-12(2)32-19-8-6-15(10-26-19)23-16-9-14(5-7-17(16)28-29-23)20-21-18(11-31-24(21)30)27-13(3)22(20)25-4/h5-10,12,20,22H,11H2,1-3H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124892 (US8759341, 25) Show SMILES Cc1[nH]nc2ccc(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])c1ccc(F)cc1 |c:19,21| Show InChI InChI=1S/C22H15FN4O2/c1-11-15-9-13(5-8-16(15)27-26-11)18-19-17(10-29-22(19)28)25-20(21(18)24-2)12-3-6-14(23)7-4-12/h3-9,18-19H,10H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124894 (US8759341, 36) Show SMILES Fc1ccc(cc1)C1=C([N+]#[C-])C(C2C(=O)OCC2=N1)c1cc2cn[nH]c2cc1F |c:8,19| Show InChI InChI=1S/C21H12F2N4O2/c1-24-20-17(13-6-11-8-25-27-15(11)7-14(13)23)18-16(9-29-21(18)28)26-19(20)10-2-4-12(22)5-3-10/h2-8,17-18H,9H2,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124895 (US8759341, 38) Show SMILES Cc1n[nH]c2cc(F)c(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])C(F)(F)F |c:20,22| Show InChI InChI=1S/C17H10F4N4O2/c1-6-7-3-8(9(18)4-10(7)25-24-6)12-13-11(5-27-16(13)26)23-15(14(12)22-2)17(19,20)21/h3-4,12-13H,5H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124896 (US8759341, 39) Show SMILES CC(C)C1=NC2=C(C(C1[N+]#[C-])c1ccc3[nH]nc(C)c3c1)C(=O)OC2 |c:5,t:3| Show InChI InChI=1S/C19H18N4O2/c1-9(2)17-18(20-4)15(16-14(21-17)8-25-19(16)24)11-5-6-13-12(7-11)10(3)22-23-13/h5-7,9,15,18H,8H2,1-3H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM149701 (US8975282, 8) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cn2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C26H24N6O4/c1-16-23(26(35)32(31(16)2)18-6-4-3-5-7-18)25(34)29-21-11-10-20(15-28-21)36-19-12-13-27-22(14-19)30-24(33)17-8-9-17/h3-7,10-15,17H,8-9H2,1-2H3,(H,27,30,33)(H,28,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	2.40	n/a	n/a	n/a	7.0	25
Sunshine Lake Pharma Co., Ltd.; Calitor Sciences, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 .mu.M KKKSPGEYVNIEFG, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activity appr...				US Patent US8975282 (2015) BindingDB Entry DOI: 10.7270/Q21V5CQD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM149702 (US8975282, 10) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(c3)C(N)=O)c(F)c2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C24H20FN5O4/c1-14-21(24(33)30(29(14)2)16-6-4-3-5-7-16)23(32)28-15-8-9-20(18(25)12-15)34-17-10-11-27-19(13-17)22(26)31/h3-13H,1-2H3,(H2,26,31)(H,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	200	n/a	n/a	n/a	7.0	25
Sunshine Lake Pharma Co., Ltd.; Calitor Sciences, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 .mu.M KKKSPGEYVNIEFG, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activity appr...				US Patent US8975282 (2015) BindingDB Entry DOI: 10.7270/Q21V5CQD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM149703 (US8975282, 11) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C27H24FN5O4/c1-16-24(27(36)33(32(16)2)19-6-4-3-5-7-19)26(35)30-18-10-11-22(21(28)14-18)37-20-12-13-29-23(15-20)31-25(34)17-8-9-17/h3-7,10-15,17H,8-9H2,1-2H3,(H,30,35)(H,29,31,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	0.5	n/a	n/a	n/a	7.0	25
Sunshine Lake Pharma Co., Ltd.; Calitor Sciences, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 .mu.M KKKSPGEYVNIEFG, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activity appr...				US Patent US8975282 (2015) BindingDB Entry DOI: 10.7270/Q21V5CQD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM149704 (US8975282, 16) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C27H25N5O4/c1-17-24(27(35)32(31(17)2)20-6-4-3-5-7-20)26(34)29-19-10-12-21(13-11-19)36-22-14-15-28-23(16-22)30-25(33)18-8-9-18/h3-7,10-16,18H,8-9H2,1-2H3,(H,29,34)(H,28,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	0.210	n/a	n/a	n/a	7.0	25
Sunshine Lake Pharma Co., Ltd.; Calitor Sciences, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 .mu.M KKKSPGEYVNIEFG, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activity appr...				US Patent US8975282 (2015) BindingDB Entry DOI: 10.7270/Q21V5CQD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156213 (US9018234, 4) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(NC(=C1[N+]#[C-])c1ccccc1)C(F)F |c:15,18| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156215 (US9018234, 10 | US9018234, 6) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(NC(=C1[N+]#[C-])c1ccc(F)cc1)C(F)F |c:15,18| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156217 (US9018234, 8) Show SMILES COc1ccc(cc1)C1=C([N+]#[C-])C(C(C#N)=C(N1)C(F)F)c1ccc2[nH]nc(C)c2c1 |c:9,16| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156215 (US9018234, 10 | US9018234, 6) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(NC(=C1[N+]#[C-])c1ccc(F)cc1)C(F)F |c:15,18| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156221 (US9018234, 13) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(NC(=C1[N+]#[C-])c1ccc(F)cc1)C(F)(F)F |c:15,18| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156228 (US9018234, 20) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(NC(=C1[N+]#[C-])c1cccnc1Cl)C(F)(F)F |c:15,18| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156230 (US9018234, A) Show SMILES COc1ccc(cc1)C1=C([N+]#[C-])C(C(C#N)=C(C)N1)c1ccc2[nH]nc(C)c2c1 |c:9,t:16| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM156231 (US9018234, B) Show SMILES Cc1n[nH]c2ccc(cc12)C1C(C#N)=C(C)NC(=C1[N+]#[C-])c1ccc(F)cc1 |c:19,t:15| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9018234 (2015) BindingDB Entry DOI: 10.7270/Q2028Q8M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM62337 (Synthetic Example 4 (WO2008/071451)) Show SMILES CC1=C(C#N)C(C(C#N)=C(C)N1)c1cccc2[nH]ncc12 |c:1,t:8| Show InChI InChI=1S/C16H13N5/c1-9-12(6-17)16(13(7-18)10(2)20-9)11-4-3-5-15-14(11)8-19-21-15/h3-5,8,16,20H,1-2H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	32
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9422263 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZW2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM168602 (US9073939, 1) Show SMILES Cc1noc2NC(C)=C([N+]#[C-])C(c12)c1ccc2[nH]nc(C)c2c1 |t:7| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9073939 (2015) BindingDB Entry DOI: 10.7270/Q2TM78WW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM168603 (US9073939, 2) Show SMILES Cc1n[nH]c2ccc(cc12)C1c2cnoc2NC(C)=C1[N+]#[C-] |c:21| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9073939 (2015) BindingDB Entry DOI: 10.7270/Q2TM78WW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM168604 (US9073939, 3) Show SMILES COc1n[nH]c2ccc(cc12)C1c2cnoc2NC(C)=C1[N+]#[C-] |c:22| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9073939 (2015) BindingDB Entry DOI: 10.7270/Q2TM78WW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM168605 (US9073939, 4) Show SMILES Cc1noc2NC(C)=C([N+]#[C-])C(c12)c1cc2c(C)n[nH]c2cc1F |t:7| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9073939 (2015) BindingDB Entry DOI: 10.7270/Q2TM78WW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM168606 (US9073939, 5) Show SMILES Cc1noc2NC(C(F)F)=C([N+]#[C-])C(c12)c1cc2c(C)n[nH]c2cc1F |t:9| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US9073939 (2015) BindingDB Entry DOI: 10.7270/Q2TM78WW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180270 (US9133162, Example 1) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C31H29FN4O5/c1-19-28(30(38)36(35(19)4)21-8-6-5-7-9-21)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(11-12-23(25)26)40-18-31(2,3)39/h5-17,39H,18H2,1-4H3,(H,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180271 (US9133162, Example 2) Show SMILES C[C@@H](O)COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 |r| Show InChI InChI=1S/C30H27FN4O5/c1-18(36)17-39-22-10-11-23-25(16-22)32-14-13-26(23)40-27-12-9-20(15-24(27)31)33-29(37)28-19(2)34(3)35(30(28)38)21-7-5-4-6-8-21/h4-16,18,36H,17H2,1-3H3,(H,33,37)/t18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180273 (US9133162, Example 4) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OCC(C)(C)O Show InChI InChI=1S/C32H31FN4O6/c1-19-29(31(39)37(36(19)4)21-9-7-6-8-10-21)30(38)35-20-11-12-26(23(33)15-20)43-25-13-14-34-24-17-28(42-18-32(2,3)40)27(41-5)16-22(24)25/h6-17,40H,18H2,1-5H3,(H,35,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180278 (US9133162, Example 9) Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C31H30N4O5/c1-20-28(30(37)35(34(20)4)22-8-6-5-7-9-22)29(36)33-21-10-12-23(13-11-21)40-27-16-17-32-26-18-24(14-15-25(26)27)39-19-31(2,3)38/h5-18,38H,19H2,1-4H3,(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180280 (US9133162, Example 11) Show SMILES C[C@@H](O)COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3)ccnc2c1 |r| Show InChI InChI=1S/C30H28N4O5/c1-19(35)18-38-24-13-14-25-26(17-24)31-16-15-27(25)39-23-11-9-21(10-12-23)32-29(36)28-20(2)33(3)34(30(28)37)22-7-5-4-6-8-22/h4-17,19,35H,18H2,1-3H3,(H,32,36)/t19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM180281 (US9133162, Example 12) Show SMILES C[C@H](O)COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3)ccnc2c1 |r| Show InChI InChI=1S/C30H28N4O5/c1-19(35)18-38-24-13-14-25-26(17-24)31-16-15-27(25)39-23-11-9-21(10-12-23)32-29(36)28-20(2)33(3)34(30(28)37)22-7-5-4-6-8-22/h4-17,19,35H,18H2,1-3H3,(H,32,36)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKSPGEYVNIEFG, 10 mM MgAcetate and [γ-33P-ATP] (specific activity approx. ...				US Patent US9133162 (2015) BindingDB Entry DOI: 10.7270/Q2FN150N
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 324 total )  |  Next  |  Last  >>

Jump to: