Compile Data Set for Download or QSAR

Found 20 hits of ph data with Target = 'Serine/threonine-protein kinase PLK2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25518 (2-amino-pyrazolopyridine, 29 | 3-[3-chloro-5-(3-me...) Show SMILES C[C@H](Nc1cc2n(nc(C)c2cn1)-c1cc(Cl)cc(CCC(N)=O)c1)c1ccccc1 |r| Show InChI InChI=1S/C24H24ClN5O/c1-15(18-6-4-3-5-7-18)28-24-13-22-21(14-27-24)16(2)29-30(22)20-11-17(8-9-23(26)31)10-19(25)12-20/h3-7,10-15H,8-9H2,1-2H3,(H2,26,31)(H,27,28)/t15-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	597	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5648-52 (2008) Article DOI: 10.1016/j.bmcl.2008.08.095 BindingDB Entry DOI: 10.7270/Q29C6VRP
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25521 (2-amino-pyrazolopyridine, 37 | N-{2-[3-chloro-5-(3...) Show SMILES C[C@H](Nc1cc2n(nc(C)c2cn1)-c1cc(Cl)cc(c1)-c1ccccc1NC(C)=O)c1ccccc1 |r| Show InChI InChI=1S/C29H26ClN5O/c1-18(21-9-5-4-6-10-21)32-29-16-28-26(17-31-29)19(2)34-35(28)24-14-22(13-23(30)15-24)25-11-7-8-12-27(25)33-20(3)36/h4-18H,1-3H3,(H,31,32)(H,33,36)/t18-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5648-52 (2008) Article DOI: 10.1016/j.bmcl.2008.08.095 BindingDB Entry DOI: 10.7270/Q29C6VRP
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM24935 (2-amino-isoxazolopyridine, 15 | 3-[3-chloro-5-(5-{...) Show SMILES C[C@H](Nc1cc2c(noc2cn1)-c1cc(Cl)cc(CCC(N)=O)c1)c1ccccc1 |r| Show InChI InChI=1S/C23H21ClN4O2/c1-14(16-5-3-2-4-6-16)27-22-12-19-20(13-26-22)30-28-23(19)17-9-15(7-8-21(25)29)10-18(24)11-17/h2-6,9-14H,7-8H2,1H3,(H2,25,29)(H,26,27)/t14-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5186-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.091 BindingDB Entry DOI: 10.7270/Q22Z13T8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM24933 (2-amino-isoxazolopyridine, 9 | 3-(2H-1,3-benzodiox...) Show SMILES C[C@H](Nc1cc2c(noc2cn1)-c1ccc2OCOc2c1)c1ccccc1 |r| Show InChI InChI=1S/C21H17N3O3/c1-13(14-5-3-2-4-6-14)23-20-10-16-19(11-22-20)27-24-21(16)15-7-8-17-18(9-15)26-12-25-17/h2-11,13H,12H2,1H3,(H,22,23)/t13-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5186-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.091 BindingDB Entry DOI: 10.7270/Q22Z13T8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM24928 (2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...) Show SMILES C[C@H](Nc1cc2c(noc2cn1)-c1cccc(C)c1)c1ccccc1 |r| Show InChI InChI=1S/C21H19N3O/c1-14-7-6-10-17(11-14)21-18-12-20(22-13-19(18)25-24-21)23-15(2)16-8-4-3-5-9-16/h3-13,15H,1-2H3,(H,22,23)/t15-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5186-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.091 BindingDB Entry DOI: 10.7270/Q22Z13T8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM8826 (3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ncnc(N)c23)c1 Show InChI InChI=1S/C20H17N5OS/c1-12-3-2-4-15(9-12)25-20(26)24-14-7-5-13(6-8-14)16-10-27-19-17(16)18(21)22-11-23-19/h2-11H,1H3,(H2,21,22,23)(H2,24,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	64	-40.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	9.30E+3	-28.4	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25113 (5-(4-aminophenyl)thieno[2,3-d]pyrimidin-4-amine | ...) Show SMILES Nc1ccc(cc1)-c1csc2ncnc(N)c12 Show InChI InChI=1S/C12H10N4S/c13-8-3-1-7(2-4-8)9-5-17-12-10(9)11(14)15-6-16-12/h1-6H,13H2,(H2,14,15,16)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25117 (AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...) Show SMILES CNC(=O)c1ccccc1Sc1ccc2c(\C=C\c3ccccn3)n[nH]c2c1 Show InChI InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM14028 ((S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]...) Show SMILES C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12-9-18-11-14-5-3-6-15(16(12)14)22(20,21)19-8-4-7-17-10-13(19)2/h3,5-6,9,11,13,17H,4,7-8,10H2,1-2H3/t13-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25116 (1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...) Show SMILES Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C Show InChI InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25115 (3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...) Show SMILES NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F Show InChI InChI=1S/C20H24BrF2N5O3S/c21-12-9-14(22)13(15(23)10-12)11-31-18-16(17(24)29)19(32-27-18)26-20(30)25-5-1-2-6-28-7-3-4-8-28/h9-10H,1-8,11H2,(H2,24,29)(H2,25,26,30)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25114 (N-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)be...) Show SMILES Nc1ncnc2scc(-c3ccc(NC(=O)c4ccccc4)cc3)c12 Show InChI InChI=1S/C19H14N4OS/c20-17-16-15(10-25-19(16)22-11-21-17)12-6-8-14(9-7-12)23-18(24)13-4-2-1-3-5-13/h1-11H,(H,23,24)(H2,20,21,22)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	>-26.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.00E+4	-25.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...				Biochemistry 46: 9551-63 (2007) Article DOI: 10.1021/bi7008745 BindingDB Entry DOI: 10.7270/Q28G8J11
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25121 (4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O |r| Show InChI InChI=1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19-20,22H,5-9,12-15H2,1-4H3,(H,30,36)(H,29,31,32)/t22-/m1/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	16.8	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Percent inhibition and IC50 values were determined with ATP concentrations at apparent Km using the Invitrogen SelectScreen Kinase Profiling Service ...				Chem Biol Drug Des 70: 540-6 (2007) Article DOI: 10.1111/j.1747-0285.2007.00594.x BindingDB Entry DOI: 10.7270/Q2T151Z8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM26514 (4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O |r| Show InChI InChI=1S/C27H37N7O2/c1-4-22-26(36)33(3)23-17-28-27(31-24(23)34(22)21-7-5-6-8-21)30-19-11-9-18(10-12-19)25(35)29-20-13-15-32(2)16-14-20/h9-12,17,20-22H,4-8,13-16H2,1-3H3,(H,29,35)(H,28,30,31)/t22-/m1/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.5	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Percent inhibition and IC50 values were determined with ATP concentrations at apparent Km using the Invitrogen SelectScreen Kinase Profiling Service ...				Chem Biol Drug Des 70: 540-6 (2007) Article DOI: 10.1111/j.1747-0285.2007.00594.x BindingDB Entry DOI: 10.7270/Q2T151Z8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM26515 (1-[4-(cyclopentylamino)-2-{[2-methoxy-4-(4-methylp...) Show SMILES COc1cc(ccc1Nc1ncc(C(C)=O)c(NC2CCCC2)n1)N1CCN(C)CC1 Show InChI InChI=1S/C23H32N6O2/c1-16(30)19-15-24-23(27-22(19)25-17-6-4-5-7-17)26-20-9-8-18(14-21(20)31-3)29-12-10-28(2)11-13-29/h8-9,14-15,17H,4-7,10-13H2,1-3H3,(H2,24,25,26,27)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Percent inhibition and IC50 values were determined with ATP concentrations at apparent Km using the Invitrogen SelectScreen Kinase Profiling Service ...				Chem Biol Drug Des 70: 540-6 (2007) Article DOI: 10.1111/j.1747-0285.2007.00594.x BindingDB Entry DOI: 10.7270/Q2T151Z8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM26516 (1-[4-(cyclopentylamino)-2-{[4-(4-methylpiperazin-1...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C(C)=O)c(NC3CCCC3)n2)cc1 Show InChI InChI=1S/C22H30N6O/c1-16(29)20-15-23-22(26-21(20)24-17-5-3-4-6-17)25-18-7-9-19(10-8-18)28-13-11-27(2)12-14-28/h7-10,15,17H,3-6,11-14H2,1-2H3,(H2,23,24,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	367	n/a	n/a	n/a	n/a	7.5	22
Pfizer					Assay Description Percent inhibition and IC50 values were determined with ATP concentrations at apparent Km using the Invitrogen SelectScreen Kinase Profiling Service ...				Chem Biol Drug Des 70: 540-6 (2007) Article DOI: 10.1111/j.1747-0285.2007.00594.x BindingDB Entry DOI: 10.7270/Q2T151Z8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM25121 (4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O |r| Show InChI InChI=1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19-20,22H,5-9,12-15H2,1-4H3,(H,30,36)(H,29,31,32)/t22-/m1/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.9	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.				US Patent US8598172 (2013) BindingDB Entry DOI: 10.7270/Q2SJ1J7D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM108214 (US8598172, 1) Show SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3cc(ccc3OC(F)(F)F)N3CCN(C)CC3)ncc2N(C)C1=O |r| Show InChI InChI=1S/C26H34F3N7O2/c1-4-22-25(37)34(3)23-17-30-26(32-24(23)36(22)19-7-5-6-8-19)31-21-15-20(35-13-11-33(2)12-14-35)10-9-18(21)16-29-38(27)28/h9-10,15,17,19,22H,4-8,11-14H2,1-3H3,(H,30,31,32)/t22-/m1/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	7.9	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.				US Patent US8598172 (2013) BindingDB Entry DOI: 10.7270/Q2SJ1J7D
					More data for this Ligand-Target Pair