BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 675 hits of ec50 data for polymerid = 1066,7101   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516578
PNG
(US11053243, Example 189b | methyl [(2S)-1-{(2S)-2-...)
Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2-c3c(F)c4cc(ccc4n3COc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00100n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM50147212
PNG
(CHEMBL3765311 | US11053243, Example 192)
Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(ccc2o1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C42H50N8O7/c1-23(2)35(47-41(53)55-5)39(51)49-17-7-9-31(49)37-43-21-29(45-37)25-11-13-26(14-12-25)34-20-28-19-27(15-16-33(28)57-34)30-22-44-38(46-30)32-10-8-18-50(32)40(52)36(24(3)4)48-42(54)56-6/h11-16,19-24,31-32,35-36H,7-10,17-18H2,1-6H3,(H,43,45)(H,44,46)(H,47,53)(H,48,54)/t31-,32-,35-,36-/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
US Patent
n/an/an/an/a 0.00200n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516573
PNG
(US11053243, Example 159 | tert-butyl {(1R)-2-[(2S)...)
Show SMILES COc1ccc(cc1)-c1c([nH]c2ccc(NC(=O)N3CCCC3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)cc12)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)OC(C)(C)C)c2ccccc2)cc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00200n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516574
PNG
(US11053243, Example 169 | tert-butyl {(1R)-2-[(2S)...)
Show SMILES Cc1cccc(c1)-c1c([nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)cc12)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)OC(C)(C)C)c2ccccc2)cc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00400n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516583
PNG
(US11053243, Example 203)
Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2oc(cc2c1)-c1ccc(-c2cnc([nH]2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)c(F)c1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00400n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516552
PNG
((2S,2'S)-N,N'-6,11-dihydro-5H- benzo[a]carbazole-3...)
Show SMILES CN(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2-c3[nH]c4ccc(NC(=O)[C@@H]5CCCN5C(=O)[C@H](N(C)C)c5ccccc5)cc4c3CCc2c1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00600n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516568
PNG
(US11053243, Example 137 | tert-butyl {(1R)-2-[(2S)...)
Show SMILES CC(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1[nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)cc2c1F |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00900n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516584
PNG
(US11053243, Example 213)
Show SMILES COC(=O)N[C@@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1nc2cc(ccc2o1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00900n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516553
PNG
((2S,2'S)-N,N'-5,6,7,12- tetrahydrobenzo[6,7]cycloh...)
Show SMILES CN(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2-c3[nH]c4ccc(NC(=O)[C@@H]5CCCN5C(=O)[C@H](N(C)C)c5ccccc5)cc4c3CCCc2c1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0100n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516563
PNG
(US11053243, Example 119 | propan-2-yl [(1R)-2-oxo-...)
Show SMILES CC(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1ncc([nH]1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC(C)C)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0130n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516576
PNG
(US11053243, Example 186 | tert-butyl {(1S)-2-[(2S)...)
Show SMILES CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1cc2cc(ccc2[nH]1)C#N)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0150n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516554
PNG
(N-(6,11-dihydro-5H- benzo[a]carbazol-3-yl)-1-{(2S)...)
Show SMILES CC(C)(C)CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2-c3[nH]c4ccccc4c3CCc2c1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0150n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516564
PNG
(US11053243, Example 125 | tert-butyl [(1R)-2-{(2S)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc2[nH]c(nc2c1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC(C)(C)C)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0160n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516580
PNG
(US11053243, Example 191)
Show SMILES CCN(CC)C(C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1nnc(o1)[C@@H]1CCCN1C(=O)[C@H](N(CC)CC)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0200n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516546
PNG
((2S)-1-[(2R)-2-phenyl-2- (pyrrolidin-1-yl)acetyl]-...)
Show SMILES O=C(Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N3CCCC3)c3ccccc3)ccc2[nH]1)[C@@H]1CCCN1C(=O)[C@H](N1CCCC1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0200n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516543
PNG
(US11053243, Example 40 | di-tert-butyl (1H,1′...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCCC1C(=O)Nc1ccc2[nH]c(cc2c1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2[nH]1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0260n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516556
PNG
(US11053243, Example 100 | benzyl (2S)-2-[5-(4-{5-[...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)OCc1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0310n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516570
PNG
(US11053243, Example 144 | tert-butyl (2S)-2-[(3-fl...)
Show SMILES CC(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1[nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)OC(C)(C)C)cc2c1F)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0360n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516555
PNG
(US11053243, Example 99 | tert-butyl {(1R)-2-[(2S)-...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC(C)(C)C)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0380n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516561
PNG
(US11053243, Example 107 | tert-butyl {(1R)-2-[(2S)...)
Show SMILES CN(C)[C@@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2[nH]1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0400n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516538
PNG
(US11053243, Example 15 | tert-butyl {(1R)-2-[(2S)-...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1nc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2[nH]1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0450n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516544
PNG
(US11053243, Example 41 | tert-butyl {(1R)-2-oxo-1-...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)Cc2ccccc2)cc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0500n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516582
PNG
((2R)-2-(diethylamino)-1- [(2S)-2-(5-{4-[5-(2-{(2S)...)
Show SMILES CCN(CC)[C@@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(ccc2o1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](N(CC)CC)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0500n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516566
PNG
(US11053243, Example 130 | tert-butyl {(1S)-2-[(2S)...)
Show SMILES CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1[nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)OC(C)(C)C)c3ccccc3)cc2c1F)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0500n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516540
PNG
((2S)-1-[(2R)-2-(diethylamino)-2- phenylacetyl]-N-(...)
Show SMILES CCN(CC)[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N(CC)CC)c3ccccc3)ccc2o1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0630n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516562
PNG
(N-(methoxycarbonyl)-L-valyl-N- {2-[4-(2-{(2S)-1-[N...)
Show SMILES CC[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)OC)C(C)C)ccc2[nH]1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0650n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516550
PNG
((2S)-1-[(2R)-2-(diethylamino)-2- phenylacetyl]-N-(...)
Show SMILES CCN(CC)[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N(CC)CC)c3ccccc3)ccc2[nH]1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0670n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516579
PNG
(US11053243, Example 190)
Show SMILES CN(C)[C@@H](C(=O)Nc1ccc2oc(nc2c1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N(C)C)c3ccccc3)ccc2[nH]1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0670n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516547
PNG
((2S)-1-(2,3-diphenylpropanoyl)- N-{4-[5-({[(2S)-1-...)
Show SMILES O=C(Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)C(Cc3ccccc3)c3ccccc3)ccc2[nH]1)[C@@H]1CCCN1C(=O)C(Cc1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0720n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516560
PNG
(US11053243, Example 105 | tert-butyl{(1R)-2-[(2S)-...)
Show SMILES CC(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)ccc2[nH]1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0800n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244736
PNG
(US10226449, cpd 346 | US9428502, 346)
Show SMILES Cc1ccc(cc1-c1[nH]c(nc1Cl)C1(C)CCOCC1)C(=O)N1CC(C1)c1ccc(cc1)C#N
Show InChI InChI=1S/C27H27ClN4O2/c1-17-3-6-20(25(33)32-15-21(16-32)19-7-4-18(14-29)5-8-19)13-22(17)23-24(28)31-26(30-23)27(2)9-11-34-12-10-27/h3-8,13,21H,9-12,15-16H2,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.100n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516549
PNG
((2S)-1-[(2R)-2phenyl-2- (piperidin-1-yl)acetyl]-N-...)
Show SMILES O=C(Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N3CCCCC3)c3ccccc3)ccc2[nH]1)[C@@H]1CCCN1C(=O)[C@H](N1CCCCC1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.130n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516577
PNG
(US11053243, Example 189a | methyl [(2S)-1-{(2S)-2-...)
Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2-c3cc4cc(ccc4n3COc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.150n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516551
PNG
((2S)-1-[(2R)-2-(dimethylamino)- 2-phenylacetyl]-N-...)
Show SMILES CN[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCO2)cc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.170n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516542
PNG
((2S,2′S) N,N′,1H,1′H-2,2′-...)
Show SMILES O=C(Cc1ccccc1)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)Cc3ccccc3)ccc2[nH]1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.240n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516572
PNG
(US11053243, Example 158 | tert-butyl {(1R)-2-[(2S)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1[nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)OC(C)(C)C)c3ccccc3)cc2c1C(=O)NC1CC1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.5n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516557
PNG
(1-[(2R)-2-(dimethylamino)-2- phenylacetyl]-N-{2-[4...)
Show SMILES CN[C@@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]c(cc2c1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](NC)c1ccccc1)c1ccccc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.5n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516565
PNG
((2S)-N-{4-[3-fluoro-5-({[(2S)-1- (phenylacetyl)pyr...)
Show SMILES Fc1c([nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)Cc3ccccc3)cc12)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)Cc2ccccc2)cc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.700n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516571
PNG
((2S) N-{4-[3-cyano-5-({[(2S)-1-(phenylacetyl)pyrro...)
Show SMILES Brc1c([nH]c2ccc(NC(=O)[C@@H]3CCCN3C(=O)Cc3ccccc3)cc12)-c1ccc(NC(=O)[C@@H]2CCCN2C(=O)Cc2ccccc2)cc1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.900n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM516548
PNG
(N-{2-[4-(acetylamino)phenyl]- 1H-indol-5-yl}-1[(2R...)
Show SMILES CC(=O)Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N3CCCC3)c3ccccc3)ccc2[nH]1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.970n/an/an/an/a


TBA

Assay Description
Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WW7MVZ
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244563
PNG
(US10226449, cpd 172 | US9428502, 172)
Show SMILES Cc1nc([nH]c1-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N)C1CCOC1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244632
PNG
(US10226449, cpd 241 | US9428502, 241)
Show SMILES Cc1ccc(cc1-c1[nH]c(nc1Cl)C1CCOCC1)C(=O)N1CC(C1)c1ccc(cc1)C#N
Show InChI InChI=1S/C26H25ClN4O2/c1-16-2-5-20(26(32)31-14-21(15-31)18-6-3-17(13-28)4-7-18)12-22(16)23-24(27)30-25(29-23)19-8-10-33-11-9-19/h2-7,12,19,21H,8-11,14-15H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244629
PNG
(US10226449, cpd 238 | US9428502, 238)
Show SMILES Cc1ccc(cc1-c1[nH]c(nc1CO)C1CC1)C(=O)N1CC(C1)c1ccc(cc1)C#N
Show InChI InChI=1S/C25H24N4O2/c1-15-2-5-19(10-21(15)23-22(14-30)27-24(28-23)18-8-9-18)25(31)29-12-20(13-29)17-6-3-16(11-26)4-7-17/h2-7,10,18,20,30H,8-9,12-14H2,1H3,(H,27,28)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM65581
PNG
(US9693997, 1)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)S(=O)(=O)c1ccc(cc1)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F
Show InChI InChI=1S/C25H28ClF3N6O4S/c1-24(2,3)39-23(36)35-10-8-17(9-11-35)40(37,38)16-6-4-14(5-7-16)20-18(25(27,28)29)12-15(13-19(20)26)31-22-32-21(30)33-34-22/h4-7,12-13,17H,8-11H2,1-3H3,(H4,30,31,32,33,34)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...

US Patent US9693997 (2017)


BindingDB Entry DOI: 10.7270/Q2833Q56
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244568
PNG
(US10226449, cpd 177 | US9428502, 177)
Show SMILES Cc1nc([nH]c1-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N)C1(C)COC1
Show InChI InChI=1S/C26H26N4O2/c1-16-4-7-20(10-22(16)23-17(2)28-25(29-23)26(3)14-32-15-26)24(31)30-12-21(13-30)19-8-5-18(11-27)6-9-19/h4-10,21H,12-15H2,1-3H3,(H,28,29)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244559
PNG
(US10226449, cpd 168 | US9428502, 168)
Show SMILES Cc1nc([nH]c1-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N)C1CCOCC1
Show InChI InChI=1S/C27H28N4O2/c1-17-3-6-22(27(32)31-15-23(16-31)20-7-4-19(14-28)5-8-20)13-24(17)25-18(2)29-26(30-25)21-9-11-33-12-10-21/h3-8,13,21,23H,9-12,15-16H2,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244555
PNG
(US10226449, cpd 164 | US9428502, 164)
Show SMILES Cc1nc([nH]c1-c1cc(C(=O)N2CC(C2)c2ccc(cc2)C#N)c(C)cc1C)C1CCOCC1
Show InChI InChI=1S/C28H30N4O2/c1-17-12-18(2)25(28(33)32-15-23(16-32)21-6-4-20(14-29)5-7-21)13-24(17)26-19(3)30-27(31-26)22-8-10-34-11-9-22/h4-7,12-13,22-23H,8-11,15-16H2,1-3H3,(H,30,31)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244738
PNG
(US10226449, cpd 348 | US9428502, 348)
Show SMILES COC(=O)N1CCC(C)(CC1)c1nc(Cl)c([nH]1)-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N
Show InChI InChI=1S/C29H30ClN5O3/c1-18-4-7-21(26(36)35-16-22(17-35)20-8-5-19(15-31)6-9-20)14-23(18)24-25(30)33-27(32-24)29(2)10-12-34(13-11-29)28(37)38-3/h4-9,14,22H,10-13,16-17H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244624
PNG
(US10226449, cpd 233 | US9428502, 233)
Show SMILES Cc1nc(CCC#N)[nH]c1-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N
Show InChI InChI=1S/C25H23N5O/c1-16-5-8-20(12-22(16)24-17(2)28-23(29-24)4-3-11-26)25(31)30-14-21(15-30)19-9-6-18(13-27)7-10-19/h5-10,12,21H,3-4,14-15H2,1-2H3,(H,28,29)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Genome polyprotein


(Hepatitis C Virus (Virus))		BDBM244622
PNG
(US10226449, cpd 231 | US9428502, 231)
Show SMILES Cc1cc(C)c(cc1C(=O)N1CC(C1)c1ccc(cc1)C#N)-c1[nH]c(CO)nc1Cl
Show InChI InChI=1S/C23H21ClN4O2/c1-13-7-14(2)19(8-18(13)21-22(24)27-20(12-29)26-21)23(30)28-10-17(11-28)16-5-3-15(9-25)4-6-16/h3-8,17,29H,10-12H2,1-2H3,(H,26,27)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2n/an/an/an/a



Conforma Therapeutics Corporation



Assay Description
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...

J Med Chem 49: 5352-62 (2006)


BindingDB Entry DOI: 10.7270/Q27M0B78
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 675 total )  |  Next  |  Last  >>
Jump to: