Compile Data Set for Download or QSAR

Found 108 hits of ec50 data for polymerid = 1808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435210 (CHEMBL2392907) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H31Cl2N7O/c1-18-24(28)26(34-25(32-18)21-10-9-20(27)16-30-21)31-17-22(19-6-3-2-4-7-19)33-23(36)8-5-13-35-14-11-29-12-15-35/h2-4,6-7,9-10,16,22,29H,5,8,11-15,17H2,1H3,(H,33,36)(H,31,32,34)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433382 (CHEMBL1329554) Show SMILES C1CN(CCO1)c1nc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C17H16N4O/c1-2-6-14-13(5-1)17(21-9-11-22-12-10-21)20-16(19-14)15-7-3-4-8-18-15/h1-8H,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435211 (CHEMBL2392906) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl)-c1ccc(F)cn1 |r| Show InChI InChI=1S/C26H31ClFN7O/c1-18-24(27)26(34-25(32-18)21-10-9-20(28)16-30-21)31-17-22(19-6-3-2-4-7-19)33-23(36)8-5-13-35-14-11-29-12-15-35/h2-4,6-7,9-10,16,22,29H,5,8,11-15,17H2,1H3,(H,33,36)(H,31,32,34)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435184 (CHEMBL2392932) Show SMILES Cc1nc(nc(NCC(CCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 Show InChI InChI=1S/C26H24Cl2N4/c1-18-24(28)26(32-25(31-18)23-15-14-22(27)17-29-23)30-16-21(20-10-6-3-7-11-20)13-12-19-8-4-2-5-9-19/h2-11,14-15,17,21H,12-13,16H2,1H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433386 (CHEMBL2375615) Show SMILES CC(O)c1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C26H26N4O/c1-19(31)20-9-11-21(12-10-20)29-14-16-30(17-15-29)26-18-25(24-8-4-5-13-27-24)28-23-7-3-2-6-22(23)26/h2-13,18-19,31H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433393 (CHEMBL2375622) Show SMILES O=Cc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H22N4O/c30-18-19-8-10-20(11-9-19)28-13-15-29(16-14-28)25-17-24(23-7-3-4-12-26-23)27-22-6-2-1-5-21(22)25/h1-12,17-18H,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435202 (CHEMBL2392914) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H25Cl2N5O/c1-18-25(29)27(34-26(32-18)22-14-13-21(28)16-30-22)31-17-23(20-10-6-3-7-11-20)33-24(35)15-12-19-8-4-2-5-9-19/h2-11,13-14,16,23H,12,15,17H2,1H3,(H,33,35)(H,31,32,34)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433373 (CHEMBL2375609) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C29H29N5O2/c1-21(35)31-27(19-22-9-3-2-4-10-22)29(36)34-17-15-33(16-18-34)28-20-26(25-13-7-8-14-30-25)32-24-12-6-5-11-23(24)28/h2-14,20,27H,15-19H2,1H3,(H,31,35)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433391 (CHEMBL2375620) Show SMILES Oc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C24H22N4O/c29-19-10-8-18(9-11-19)27-13-15-28(16-14-27)24-17-23(22-7-3-4-12-25-22)26-21-6-2-1-5-20(21)24/h1-12,17,29H,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433387 (CHEMBL2375616) Show SMILES CCOC(=O)c1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C27H26N4O2/c1-2-33-27(32)20-10-12-21(13-11-20)30-15-17-31(18-16-30)26-19-25(24-9-5-6-14-28-24)29-23-8-4-3-7-22(23)26/h3-14,19H,2,15-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433395 (CHEMBL2375624) Show SMILES COc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H24N4O/c1-30-20-11-9-19(10-12-20)28-14-16-29(17-15-28)25-18-24(23-8-4-5-13-26-23)27-22-7-3-2-6-21(22)25/h2-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433381 (CHEMBL2375613) Show SMILES C1CCN(CC1)c1nc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H18N4/c1-6-12-22(13-7-1)18-14-8-2-3-9-15(14)20-17(21-18)16-10-4-5-11-19-16/h2-5,8-11H,1,6-7,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433392 (CHEMBL2375621) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C24H21N5O2/c30-29(31)19-10-8-18(9-11-19)27-13-15-28(16-14-27)24-17-23(22-7-3-4-12-25-22)26-21-6-2-1-5-20(21)24/h1-12,17H,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433380 (CHEMBL2375612) Show SMILES C(Cc1[nH]cc2ccccc12)Nc1nc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C23H19N5/c1-2-8-17-16(7-1)15-26-19(17)12-14-25-22-18-9-3-4-10-20(18)27-23(28-22)21-11-5-6-13-24-21/h1-11,13,15,26H,12,14H2,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433374 (CHEMBL2375610) Show SMILES CC(=O)Nc1ncc(CC(=O)N2CCN(CC2)c2cc(nc3ccccc23)-c2ccccn2)s1 Show InChI InChI=1S/C25H24N6O2S/c1-17(32)28-25-27-16-18(34-25)14-24(33)31-12-10-30(11-13-31)23-15-22(21-8-4-5-9-26-21)29-20-7-3-2-6-19(20)23/h2-9,15-16H,10-14H2,1H3,(H,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435207 (CHEMBL2392910) Show SMILES CN(C)c1ccc(nc1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 |r| Show InChI InChI=1S/C28H37ClN8O/c1-20-26(29)28(35-27(33-20)23-12-11-22(18-31-23)36(2)3)32-19-24(21-8-5-4-6-9-21)34-25(38)10-7-15-37-16-13-30-14-17-37/h4-6,8-9,11-12,18,24,30H,7,10,13-17,19H2,1-3H3,(H,34,38)(H,32,33,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435201 (CHEMBL2392915) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C28H27Cl2N5O/c1-19-26(30)28(35-27(33-19)23-16-15-22(29)17-31-23)32-18-24(21-12-6-3-7-13-21)34-25(36)14-8-11-20-9-4-2-5-10-20/h2-7,9-10,12-13,15-17,24H,8,11,14,18H2,1H3,(H,34,36)(H,32,33,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435183 (CHEMBL2392933) Show SMILES Cc1nc(nc(NCC(CCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 Show InChI InChI=1S/C27H26Cl2N4/c1-19-25(29)27(33-26(32-19)24-16-15-23(28)18-30-24)31-17-22(21-12-6-3-7-13-21)14-8-11-20-9-4-2-5-10-20/h2-7,9-10,12-13,15-16,18,22H,8,11,14,17H2,1H3,(H,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433389 (CHEMBL2375618) Show SMILES CCOC(=O)COc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C28H28N4O3/c1-2-34-28(33)20-35-22-12-10-21(11-13-22)31-15-17-32(18-16-31)27-19-26(25-9-5-6-14-29-25)30-24-8-4-3-7-23(24)27/h3-14,19H,2,15-18,20H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433375 (CHEMBL472879 | GNF-Pf-359) Show SMILES Cc1nc(nc(NCCc2ccccc2)c1Cl)-c1ccccn1 Show InChI InChI=1S/C18H17ClN4/c1-13-16(19)18(21-12-10-14-7-3-2-4-8-14)23-17(22-13)15-9-5-6-11-20-15/h2-9,11H,10,12H2,1H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435182 (CHEMBL2392934) Show SMILES Cc1nc(nc(NCC(CCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 Show InChI InChI=1S/C28H28Cl2N4/c1-20-26(30)28(34-27(33-20)25-17-16-24(29)19-31-25)32-18-23(22-13-6-3-7-14-22)15-9-8-12-21-10-4-2-5-11-21/h2-7,10-11,13-14,16-17,19,23H,8-9,12,15,18H2,1H3,(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435195 (CHEMBL2392921) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C28H29Cl2N5/c1-20-26(30)28(35-27(34-20)24-16-15-23(29)18-32-24)33-19-25(22-13-6-3-7-14-22)31-17-9-8-12-21-10-4-2-5-11-21/h2-7,10-11,13-16,18,25,31H,8-9,12,17,19H2,1H3,(H,33,34,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435198 (CHEMBL2392918) Show SMILES Cc1nc(nc(NC[C@H](NCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H23Cl2N5/c1-17-23(27)25(32-24(31-17)21-13-12-20(26)15-29-21)30-16-22(19-10-6-3-7-11-19)28-14-18-8-4-2-5-9-18/h2-13,15,22,28H,14,16H2,1H3,(H,30,31,32)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433399 (CHEMBL2375608) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H24N4O2S/c1-19-9-11-20(12-10-19)32(30,31)29-16-14-28(15-17-29)25-18-24(23-8-4-5-13-26-23)27-22-7-3-2-6-21(22)25/h2-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435196 (CHEMBL2392920) Show SMILES Cc1nc(nc(NC[C@H](NCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H27Cl2N5/c1-19-25(29)27(34-26(33-19)23-15-14-22(28)17-31-23)32-18-24(21-12-6-3-7-13-21)30-16-8-11-20-9-4-2-5-10-20/h2-7,9-10,12-15,17,24,30H,8,11,16,18H2,1H3,(H,32,33,34)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435197 (CHEMBL2392919) Show SMILES Cc1nc(nc(NC[C@H](NCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H25Cl2N5/c1-18-24(28)26(33-25(32-18)22-13-12-21(27)16-30-22)31-17-23(20-10-6-3-7-11-20)29-15-14-19-8-4-2-5-9-19/h2-13,16,23,29H,14-15,17H2,1H3,(H,31,32,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435212 (CHEMBL2392905) Show SMILES COc1ccc(nc1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 |r| Show InChI InChI=1S/C27H34ClN7O2/c1-19-25(28)27(34-26(32-19)22-11-10-21(37-2)17-30-22)31-18-23(20-7-4-3-5-8-20)33-24(36)9-6-14-35-15-12-29-13-16-35/h3-5,7-8,10-11,17,23,29H,6,9,12-16,18H2,1-2H3,(H,33,36)(H,31,32,34)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433377 (CHEMBL2375628) Show SMILES Cc1nc(nc(NCCNc2ccc(cn2)C(F)(F)F)c1Cl)-c1ccccn1 Show InChI InChI=1S/C18H16ClF3N6/c1-11-15(19)17(28-16(27-11)13-4-2-3-7-23-13)25-9-8-24-14-6-5-12(10-26-14)18(20,21)22/h2-7,10H,8-9H2,1H3,(H,24,26)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435208 (CHEMBL2392909) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl)-c1ccc(cn1)[N+]([O-])=O |r| Show InChI InChI=1S/C26H31ClN8O3/c1-18-24(27)26(33-25(31-18)21-10-9-20(16-29-21)35(37)38)30-17-22(19-6-3-2-4-7-19)32-23(36)8-5-13-34-14-11-28-12-15-34/h2-4,6-7,9-10,16,22,28H,5,8,11-15,17H2,1H3,(H,32,36)(H,30,31,33)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435209 (CHEMBL2392908) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl)-c1ccc(Br)cn1 |r| Show InChI InChI=1S/C26H31BrClN7O/c1-18-24(28)26(34-25(32-18)21-10-9-20(27)16-30-21)31-17-22(19-6-3-2-4-7-19)33-23(36)8-5-13-35-14-11-29-12-15-35/h2-4,6-7,9-10,16,22,29H,5,8,11-15,17H2,1H3,(H,33,36)(H,31,32,34)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435188 (CHEMBL2392928) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccco2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H27Cl2N5O/c1-18-24(28)26(33-25(32-18)22-13-12-20(27)16-30-22)31-17-23(19-8-3-2-4-9-19)29-14-6-5-10-21-11-7-15-34-21/h2-4,7-9,11-13,15-16,23,29H,5-6,10,14,17H2,1H3,(H,31,32,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17847 (CHEMBL327579 | pyridine-2-carboxylic acid inhibito...) Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17847 (CHEMBL327579 | pyridine-2-carboxylic acid inhibito...) Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435187 (CHEMBL2392929) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2cccs2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H27Cl2N5S/c1-18-24(28)26(33-25(32-18)22-13-12-20(27)16-30-22)31-17-23(19-8-3-2-4-9-19)29-14-6-5-10-21-11-7-15-34-21/h2-4,7-9,11-13,15-16,23,29H,5-6,10,14,17H2,1H3,(H,31,32,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433398 (CHEMBL2375607) Show SMILES Clc1ccc(cc1Cl)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C24H20Cl2N4/c25-19-9-8-17(15-20(19)26)29-11-13-30(14-12-29)24-16-23(22-7-3-4-10-27-22)28-21-6-2-1-5-18(21)24/h1-10,15-16H,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433383 (CHEMBL2375614) Show SMILES C1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C19H19N3/c1-6-12-22(13-7-1)19-14-18(17-10-4-5-11-20-17)21-16-9-3-2-8-15(16)19/h2-5,8-11,14H,1,6-7,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433384 (CHEMBL45721) Show SMILES C1CN(CCO1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H17N3O/c1-2-6-15-14(5-1)18(21-9-11-22-12-10-21)13-17(20-15)16-7-3-4-8-19-16/h1-8,13H,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435192 (CHEMBL2392924) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(O)cc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C28H29Cl2N5O/c1-19-26(30)28(35-27(34-19)24-15-12-22(29)17-32-24)33-18-25(21-8-3-2-4-9-21)31-16-6-5-7-20-10-13-23(36)14-11-20/h2-4,8-15,17,25,31,36H,5-7,16,18H2,1H3,(H,33,34,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433376 (CHEMBL2375627) Show SMILES Cc1nc(nc(NC[C@@H](NCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C28H29Cl2N5/c1-20-26(30)28(35-27(34-20)24-16-15-23(29)18-32-24)33-19-25(22-13-6-3-7-14-22)31-17-9-8-12-21-10-4-2-5-11-21/h2-7,10-11,13-16,18,25,31H,8-9,12,17,19H2,1H3,(H,33,34,35)/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435185 (CHEMBL2392931) Show SMILES Cc1nc(nc(NC[C@H](NCCCCn2cccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H28Cl2N6/c1-19-24(28)26(33-25(32-19)22-12-11-21(27)17-30-22)31-18-23(20-9-3-2-4-10-20)29-13-5-6-14-34-15-7-8-16-34/h2-4,7-12,15-17,23,29H,5-6,13-14,18H2,1H3,(H,31,32,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435190 (CHEMBL2392926) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(cc2)C#N)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C29H28Cl2N6/c1-20-27(31)29(37-28(36-20)25-15-14-24(30)18-34-25)35-19-26(23-8-3-2-4-9-23)33-16-6-5-7-21-10-12-22(17-32)13-11-21/h2-4,8-15,18,26,33H,5-7,16,19H2,1H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435205 (CHEMBL2392912) Show SMILES COc1ccnc(c1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 |r| Show InChI InChI=1S/C27H34ClN7O2/c1-19-25(28)27(34-26(32-19)22-17-21(37-2)10-11-30-22)31-18-23(20-7-4-3-5-8-20)33-24(36)9-6-14-35-15-12-29-13-16-35/h3-5,7-8,10-11,17,23,29H,6,9,12-16,18H2,1-2H3,(H,33,36)(H,31,32,34)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435191 (CHEMBL2392925) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(Cl)cc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C28H28Cl3N5/c1-19-26(31)28(36-27(35-19)24-15-14-23(30)17-33-24)34-18-25(21-8-3-2-4-9-21)32-16-6-5-7-20-10-12-22(29)13-11-20/h2-4,8-15,17,25,32H,5-7,16,18H2,1H3,(H,34,35,36)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433394 (CHEMBL2375623) Show SMILES C=CCOc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C27H26N4O/c1-2-19-32-22-12-10-21(11-13-22)30-15-17-31(18-16-30)27-20-26(25-9-5-6-14-28-25)29-24-8-4-3-7-23(24)27/h2-14,20H,1,15-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435199 (CHEMBL2392917) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)CCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C30H31Cl2N5O/c1-21-28(32)30(37-29(35-21)25-18-17-24(31)19-33-25)34-20-26(23-14-8-4-9-15-23)36-27(38)16-10-3-7-13-22-11-5-2-6-12-22/h2,4-6,8-9,11-12,14-15,17-19,26H,3,7,10,13,16,20H2,1H3,(H,36,38)(H,34,35,37)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435186 (CHEMBL2392930) Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc3ccccc3n2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C31H30Cl2N6/c1-21-29(33)31(39-30(37-21)27-17-15-24(32)19-35-27)36-20-28(22-9-3-2-4-10-22)34-18-8-7-12-25-16-14-23-11-5-6-13-26(23)38-25/h2-6,9-11,13-17,19,28,34H,7-8,12,18,20H2,1H3,(H,36,37,39)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435203 (CHEMBL2390976) Show SMILES Cc1nc(nc(NC[C@H](NC(=O)Cc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H23Cl2N5O/c1-17-24(28)26(33-25(31-17)21-13-12-20(27)15-29-21)30-16-22(19-10-6-3-7-11-19)32-23(34)14-18-8-4-2-5-9-18/h2-13,15,22H,14,16H2,1H3,(H,32,34)(H,30,31,33)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50433375 (CHEMBL472879 | GNF-Pf-359) Show SMILES Cc1nc(nc(NCCc2ccccc2)c1Cl)-c1ccccn1 Show InChI InChI=1S/C18H17ClN4/c1-13-16(19)18(21-12-10-14-7-3-2-4-8-14)23-17(22-13)15-9-5-6-11-20-15/h2-9,11H,10,12H2,1H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Zn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50435193 (CHEMBL2392923) Show SMILES Cc1nc(nc(NC[C@H](NCCCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C30H33Cl2N5/c1-22-28(32)30(37-29(36-22)26-18-17-25(31)20-34-26)35-21-27(24-15-9-5-10-16-24)33-19-11-3-2-6-12-23-13-7-4-8-14-23/h4-5,7-10,13-18,20,27,33H,2-3,6,11-12,19,21H2,1H3,(H,35,36,37)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair

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