Found 752 hits of ec50 data for polymerid = 2071,50004763,6342 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50305285
(CHEMBL595262 | [(1R,2R,6R,10S,11R,13S,15R,17R)-13-...)Show SMILES COc1cc(OC(=O)OCC2=C[C@H]3[C@H]4O[C@]5(Cc6ccccc6)O[C@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)cc(I)c1O |r,t:10,35,TLB:16:15:12:25.26.24,THB:23:15:12:25.26.24| Show InChI InChI=1S/C36H37IO10/c1-19(2)34-15-21(4)36-25(31(34)45-35(46-34,47-36)17-22-9-7-6-8-10-22)12-23(16-33(41)28(36)11-20(3)30(33)39)18-43-32(40)44-24-13-26(37)29(38)27(14-24)42-5/h6-14,21,25,28,31,38,41H,1,15-18H2,2-5H3/t21-,25+,28-,31-,33-,34-,35-,36-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level |
Bioorg Med Chem Lett 20: 97-9 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.035
BindingDB Entry DOI: 10.7270/Q2W37X84 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant TRPV1 expressed in human HEK293 cells |
Bioorg Med Chem Lett 17: 132-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.077
BindingDB Entry DOI: 10.7270/Q2FN170G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level |
Bioorg Med Chem Lett 20: 97-9 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.035
BindingDB Entry DOI: 10.7270/Q2W37X84 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50247741
(CHEMBL503101 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1NS(C)(=O)=O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C38H43NO10S/c1-22(2)36-18-24(4)38-28(34(36)47-37(48-36,49-38)20-25-10-8-7-9-11-25)15-27(19-35(42)31(38)14-23(3)33(35)41)21-46-32(40)17-26-12-13-29(30(16-26)45-5)39-50(6,43)44/h7-16,24,28,31,34,39,42H,1,17-21H2,2-6H3/t24-,28+,31-,34-,35-,36+,37?,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.106 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50305283
(CHEMBL594016 | [(1R,2R,6R,10S,11R,13S,15R,17R)-13-...)Show SMILES COc1cc(ccc1O)C(=C)C(=O)OCC1=C[C@H]2[C@H]3O[C@]4(Cc5ccccc5)O[C@]3(C[C@@H](C)[C@]2(O4)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1)C(C)=C |r,t:16,41,TLB:21:20:17:30.31.29,THB:28:20:17:30.31.29| Show InChI InChI=1S/C38H40O9/c1-21(2)36-17-23(4)38-28(33(36)45-37(46-36,47-38)19-25-10-8-7-9-11-25)15-26(18-35(42)31(38)14-22(3)32(35)40)20-44-34(41)24(5)27-12-13-29(39)30(16-27)43-6/h7-16,23,28,31,33,39,42H,1,5,17-20H2,2-4,6H3/t23-,28+,31-,33-,35-,36-,37-,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level |
Bioorg Med Chem Lett 20: 97-9 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.035
BindingDB Entry DOI: 10.7270/Q2W37X84 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake |
Bioorg Med Chem Lett 21: 299-302 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.012
BindingDB Entry DOI: 10.7270/Q2J967BB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473857
(CHEMBL124602)Show SMILES CCCCCC[C@H](C\C=C/CCCCCCCC(=O)NCc1ccc(O)c(OC)c1)OC(C)=O Show InChI InChI=1S/C28H45NO5/c1-4-5-6-13-16-25(34-23(2)30)17-14-11-9-7-8-10-12-15-18-28(32)29-22-24-19-20-26(31)27(21-24)33-3/h11,14,19-21,25,31H,4-10,12-13,15-18,22H2,1-3H3,(H,29,32)/b14-11-/t25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.398 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50333930
(CHEMBL1644419 | [(2R,6R,10S,15S,17R)-13-benzyl-6-h...)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3C4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)C3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1N |r,t:10,35,TLB:39:24:12:29.14.15,THB:23:24:12:29.14.15,23:15:12:24.25.26,27:26:12:29.14.15| Show InChI InChI=1S/C37H41NO8/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,41H,1,16-20,38H2,2-5H3/t23-,27+,30-,33?,34-,35+,36?,37?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake |
Bioorg Med Chem Lett 21: 299-302 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.012
BindingDB Entry DOI: 10.7270/Q2J967BB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20460
((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)Show InChI InChI=1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473844
(CHEMBL123254)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccc(O)c(OC)c1 Show InChI InChI=1S/C28H41NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-28(31)29-24-25-21-22-26(30)27(23-25)32-2/h7-8,10-11,13-14,16-17,21-23,30H,3-6,9,12,15,18-20,24H2,1-2H3,(H,29,31)/b8-7-,11-10-,14-13-,17-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473843
(CHEMBL121808)Show SMILES [#6]-[#8]-c1cc(-[#6]-[#7]-[#6](=O)\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])ccc1-[#8] Show InChI InChI=1S/C23H33NO3/c1-17(2)8-6-9-18(3)10-7-11-19(4)14-23(26)24-16-20-12-13-21(25)22(15-20)27-5/h8,10,12-15,25H,6-7,9,11,16H2,1-5H3,(H,24,26)/b18-10+,19-14+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50473844
(CHEMBL123254)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccc(O)c(OC)c1 Show InChI InChI=1S/C28H41NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-28(31)29-24-25-21-22-26(30)27(23-25)32-2/h7-8,10-11,13-14,16-17,21-23,30H,3-6,9,12,15,18-20,24H2,1-2H3,(H,29,31)/b8-7-,11-10-,14-13-,17-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at TRPV1 in rat isolated mesenteric arteries assessed as vasorelaxation of phenylephrine-induced contraction |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.113042
BindingDB Entry DOI: 10.7270/Q20Z7718 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20313
((2R)-2-[(4-tert-butylphenyl)methyl]-3-[(2S)-2-(3-f...)Show SMILES C[C@H](C(=O)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 |r| Show InChI InChI=1S/C29H41FN2O5S/c1-19(22-11-14-25(24(30)16-22)32-38(8,35)36)26(33)31-17-21(18-37-27(34)29(5,6)7)15-20-9-12-23(13-10-20)28(2,3)4/h9-14,16,19,21,32H,15,17-18H2,1-8H3,(H,31,33)/t19-,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.12 | -49.8 | n/a | n/a | 0.580 | n/a | n/a | 7.4 | 37 |
Seoul National University
| Assay Description
Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b... |
J Med Chem 51: 57-67 (2008)
Article DOI: 10.1021/jm701049p
BindingDB Entry DOI: 10.7270/Q2222S1N |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50305281
(CHEMBL594649 | [(1R,2R,6R,10S,11R,13S,15R,17R)-13-...)Show SMILES COc1cc(ccc1O)C(OC(C)=O)C(=O)OCC1=C[C@H]2[C@H]3O[C@]4(Cc5ccccc5)O[C@]3(C[C@@H](C)[C@]2(O4)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1)C(C)=C |r,t:19,44,TLB:24:23:20:33.34.32,THB:31:23:20:33.34.32| Show InChI InChI=1S/C39H42O11/c1-21(2)37-17-23(4)39-28(34(37)48-38(49-37,50-39)19-25-10-8-7-9-11-25)15-26(18-36(44)31(39)14-22(3)33(36)42)20-46-35(43)32(47-24(5)40)27-12-13-29(41)30(16-27)45-6/h7-16,23,28,31-32,34,41,44H,1,17-20H2,2-6H3/t23-,28+,31-,32?,34-,36-,37-,38-,39-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level |
Bioorg Med Chem Lett 20: 97-9 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.035
BindingDB Entry DOI: 10.7270/Q2W37X84 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in CHO cells assessed as stimulation of Ca2+ uptake |
Eur J Med Chem 68: 233-43 (2013)
Article DOI: 10.1016/j.ejmech.2013.07.042
BindingDB Entry DOI: 10.7270/Q2RB761G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysis |
Bioorg Med Chem Lett 24: 382-5 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.064
BindingDB Entry DOI: 10.7270/Q29K4CP9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50305282
(CHEMBL594895 | [(1R,2R,6R,10S,11R,13S,15R,17R)-13-...)Show SMILES COc1cc(ccc1O)C(C)C(=O)OCC1=C[C@H]2[C@H]3O[C@]4(Cc5ccccc5)O[C@]3(C[C@@H](C)[C@]2(O4)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1)C(C)=C |r,t:16,41,TLB:21:20:17:30.31.29,THB:28:20:17:30.31.29| Show InChI InChI=1S/C38H42O9/c1-21(2)36-17-23(4)38-28(33(36)45-37(46-36,47-38)19-25-10-8-7-9-11-25)15-26(18-35(42)31(38)14-22(3)32(35)40)20-44-34(41)24(5)27-12-13-29(39)30(16-27)43-6/h7-16,23-24,28,31,33,39,42H,1,17-20H2,2-6H3/t23-,24?,28+,31-,33-,35-,36-,37-,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.980 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level |
Bioorg Med Chem Lett 20: 97-9 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.035
BindingDB Entry DOI: 10.7270/Q2W37X84 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50444876
(CHEMBL3099608)Show SMILES COc1cc(CNC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1O |r| Show InChI InChI=1S/C28H40N2O4S/c1-27(2,3)22-11-8-19(9-12-22)14-21(18-34-25(32)28(4,5)6)17-30-26(35)29-16-20-10-13-23(31)24(15-20)33-7/h8-13,15,21,31H,14,16-18H2,1-7H3,(H2,29,30,35)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.990 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysis |
Bioorg Med Chem Lett 24: 382-5 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.064
BindingDB Entry DOI: 10.7270/Q29K4CP9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50333931
(CHEMBL1644420 | [(2R,6R,10S,15S,17R)-13-benzyl-6-h...)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3C4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)C3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)cc(F)c1N |r,t:10,35,TLB:39:24:12:29.14.15,THB:23:24:12:29.14.15,23:15:12:24.25.26,27:26:12:29.14.15| Show InChI InChI=1S/C37H40FNO8/c1-20(2)35-16-22(4)37-26(33(35)45-36(46-35,47-37)18-23-9-7-6-8-10-23)12-25(17-34(42)29(37)11-21(3)32(34)41)19-44-30(40)15-24-13-27(38)31(39)28(14-24)43-5/h6-14,22,26,29,33,42H,1,15-19,39H2,2-5H3/t22-,26+,29-,33?,34-,35+,36?,37?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.14 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake |
Bioorg Med Chem Lett 21: 299-302 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.012
BindingDB Entry DOI: 10.7270/Q2J967BB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50246639
(CHEMBL472898 | N-(4-hydroxy-3-methoxyphenyl)icosa-...)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc(O)c(OC)c1 Show InChI InChI=1S/C27H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(30)28-24-21-22-25(29)26(23-24)31-2/h7-8,10-11,13-14,16-17,21-23,29H,3-6,9,12,15,18-20H2,1-2H3,(H,28,30)/b8-7-,11-10-,14-13-,17-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at TRPV1 in rat isolated mesenteric arteries assessed as vasorelaxation of phenylephrine-induced contraction |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.113042
BindingDB Entry DOI: 10.7270/Q20Z7718 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50196343
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1O Show InChI InChI=1S/C28H40N2O4S/c1-27(2,3)22-11-8-19(9-12-22)14-21(18-34-25(32)28(4,5)6)17-30-26(35)29-16-20-10-13-23(31)24(15-20)33-7/h8-13,15,21,31H,14,16-18H2,1-7H3,(H2,29,30,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysis |
Bioorg Med Chem Lett 24: 382-5 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.064
BindingDB Entry DOI: 10.7270/Q29K4CP9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473859
(CHEMBL124002)Show SMILES CCCCCCCC[C@@H]1C[C@@H]1CCCCCCCC(=O)NCc1ccc(O)c(OC)c1 Show InChI InChI=1S/C27H45NO3/c1-3-4-5-6-8-11-14-23-20-24(23)15-12-9-7-10-13-16-27(30)28-21-22-17-18-25(29)26(19-22)31-2/h17-19,23-24,29H,3-16,20-21H2,1-2H3,(H,28,30)/t23-,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473845
(CHEMBL122864)Show SMILES CCCCCC\C=C\C#CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 Show InChI InChI=1S/C26H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h8-9,19-21,28H,3-7,12-18,22H2,1-2H3,(H,27,29)/b9-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50196616
((E)-3-(4-hydroxy-3-methoxy-phenyl)-acrylic acid (3...)Show SMILES COc1cc(\C=C\C(=O)OCC2=C[C@H]3[C@H]4OCO[C@]4(C[C@@H](C)[C@]3(OCc3ccccc3)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |t:11,35| Show InChI InChI=1S/C38H42O9/c1-23(2)37-18-25(4)38(46-21-27-9-7-6-8-10-27)29(35(37)45-22-47-37)16-28(19-36(42)32(38)15-24(3)34(36)41)20-44-33(40)14-12-26-11-13-30(39)31(17-26)43-5/h6-17,25,29,32,35,39,42H,1,18-22H2,2-5H3/b14-12+/t25-,29+,32-,35-,36-,37-,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant TRPV1 expressed in human HEK293 cells |
Bioorg Med Chem Lett 17: 132-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.077
BindingDB Entry DOI: 10.7270/Q2FN170G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50595685
(CHEMBL5173171)Show SMILES Clc1ccc(nc1)N1CCN(CC1)C(=O)Nc1ccc2cn[nH]c2c1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2RN3CWB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473848
(CHEMBL333489)Show SMILES COc1ccc(CNC(=O)CCCCCCCCCCCC\C=C\CCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O Show InChI InChI=1S/C36H54N2O6/c1-43-33-23-21-29(25-31(33)39)27-37-35(41)19-17-15-13-11-9-7-5-3-4-6-8-10-12-14-16-18-20-36(42)38-28-30-22-24-34(44-2)32(40)26-30/h9,11,21-26,39-40H,3-8,10,12-20,27-28H2,1-2H3,(H,37,41)(H,38,42)/b11-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50247743
(CHEMBL504206 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]2C=C(COC(=O)Cc4ccc(NS(C)(=O)=O)cc4)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)C(C)=C |r,t:18,41,TLB:6:5:15:3.2.1,THB:4:5:15:3.2.1| Show InChI InChI=1S/C37H41NO9S/c1-22(2)35-18-24(4)37-29(33(35)45-36(46-35,47-37)20-26-9-7-6-8-10-26)16-27(19-34(41)30(37)15-23(3)32(34)40)21-44-31(39)17-25-11-13-28(14-12-25)38-48(5,42)43/h6-16,24,29-30,33,38,41H,1,17-21H2,2-5H3/t24-,29+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.78 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50247748
(CHEMBL510228 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]2C=C(COC(=O)Cc4ccc(F)cc4F)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)C(C)=C |r,t:18,38,TLB:6:5:15:3.2.1,THB:4:5:15:3.2.1| Show InChI InChI=1S/C36H36F2O7/c1-20(2)34-16-22(4)36-27(32(34)43-35(44-34,45-36)18-23-8-6-5-7-9-23)13-24(17-33(41)29(36)12-21(3)31(33)40)19-42-30(39)14-25-10-11-26(37)15-28(25)38/h5-13,15,22,27,29,32,41H,1,14,16-19H2,2-4H3/t22-,27+,29-,32-,33-,34+,35?,36-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50440401
(CHEMBL2425550)Show SMILES COc1cc(OC(=O)OCC2=C[C@H]3[C@H]4O[C@]5(Cc6ccccc6)O[C@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1N |r,t:10,35,TLB:16:15:12:24.25.26,THB:23:15:12:24.25.26| Show InChI InChI=1S/C36H39NO9/c1-20(2)34-16-22(4)36-26(31(34)44-35(45-34,46-36)18-23-9-7-6-8-10-23)14-24(17-33(40)29(36)13-21(3)30(33)38)19-42-32(39)43-25-11-12-27(37)28(15-25)41-5/h6-15,22,26,29,31,40H,1,16-19,37H2,2-5H3/t22-,26+,29-,31-,33-,34-,35-,36-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as stimulation of Ca2+ uptake |
Eur J Med Chem 68: 233-43 (2013)
Article DOI: 10.1016/j.ejmech.2013.07.042
BindingDB Entry DOI: 10.7270/Q2RB761G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50333925
(CHEMBL1644414 | [(2R,6R,10S,15S,17R)-13-benzyl-6-h...)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3C4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)C3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)cc(F)c1O |r,t:10,35,TLB:39:24:12:29.14.15,THB:23:24:12:29.14.15,23:15:12:24.25.26,27:26:12:29.14.15| Show InChI InChI=1S/C37H39FO9/c1-20(2)35-16-22(4)37-26(33(35)45-36(46-35,47-37)18-23-9-7-6-8-10-23)12-25(17-34(42)29(37)11-21(3)32(34)41)19-44-30(39)15-24-13-27(38)31(40)28(14-24)43-5/h6-14,22,26,29,33,40,42H,1,15-19H2,2-5H3/t22-,26+,29-,33?,34-,35+,36?,37?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.88 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake |
Bioorg Med Chem Lett 21: 299-302 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.012
BindingDB Entry DOI: 10.7270/Q2J967BB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50196621
(4-hydroxy-3-iodo-5-methoxy-benzoic acid (3aR,3bR,4...)Show SMILES COc1cc(cc(I)c1O)C(=O)OCC1=C[C@H]2[C@H]3OCO[C@]3(C[C@@H](C)[C@]2(OCc2ccccc2)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1)C(C)=C |t:15,39| Show InChI InChI=1S/C36H39IO9/c1-20(2)35-15-22(4)36(45-18-23-9-7-6-8-10-23)26(32(35)44-19-46-35)12-24(16-34(41)29(36)11-21(3)31(34)39)17-43-33(40)25-13-27(37)30(38)28(14-25)42-5/h6-14,22,26,29,32,38,41H,1,15-19H2,2-5H3/t22-,26+,29-,32-,34-,35-,36-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Agonist activity at human recombinant TRPV1 expressed in human HEK293 cells |
Bioorg Med Chem Lett 17: 132-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.077
BindingDB Entry DOI: 10.7270/Q2FN170G |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50366620
(RESINIFERATOXIN)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OC5(Cc6ccccc6)O[C@@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,TLB:23:15:12:24.25.26,THB:16:15:12:24.25.26| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cells |
Bioorg Med Chem Lett 12: 1189-92 (2002)
BindingDB Entry DOI: 10.7270/Q2VX0H2S |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50247745
(CHEMBL455555 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]2C=C(COC(=O)Cc4cccc(F)c4)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)C(C)=C |r,t:18,37,TLB:6:5:15:3.2.1,THB:4:5:15:3.2.1| Show InChI InChI=1S/C36H37FO7/c1-21(2)34-17-23(4)36-28(32(34)42-35(43-34,44-36)19-24-9-6-5-7-10-24)15-26(18-33(40)29(36)13-22(3)31(33)39)20-41-30(38)16-25-11-8-12-27(37)14-25/h5-15,23,28-29,32,40H,1,16-20H2,2-4H3/t23-,28+,29-,32-,33-,34+,35?,36-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.92 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196337
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1O Show InChI InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.97 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196337
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1O Show InChI InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake |
Bioorg Med Chem Lett 17: 214-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.059
BindingDB Entry DOI: 10.7270/Q27D2TSX |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473855
(CHEMBL313885)Show InChI InChI=1S/C19H29NO3/c1-3-4-5-6-7-8-9-10-11-19(22)20-15-16-12-13-17(21)18(14-16)23-2/h3,12-14,21H,1,4-11,15H2,2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473841
(CHEMBL124415)Show SMILES COc1cc(CNC(=O)\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)ccc1O Show InChI InChI=1S/C28H47NO3/c1-21(2)10-7-11-22(3)12-8-13-23(4)14-9-15-24(5)18-28(31)29-20-25-16-17-26(30)27(19-25)32-6/h16-19,21-23,30H,7-15,20H2,1-6H3,(H,29,31)/b24-18+/t22-,23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50415874
(CHEMBL1095331)Show InChI InChI=1S/C15H19NO3/c1-19-14-11-12(5-7-13(14)17)6-8-15(18)16-9-3-2-4-10-16/h5-8,11,17H,2-4,9-10H2,1H3/b8-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Universidad de Antioquia
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu... |
Bioorg Med Chem 18: 3299-306 (2010)
Article DOI: 10.1016/j.bmc.2010.03.013
BindingDB Entry DOI: 10.7270/Q24M95RD |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20334
(1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...)Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | 7.4 | 22 |
Abbott Laboratories
| Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0... |
J Med Chem 50: 3651-60 (2007)
Article DOI: 10.1021/jm070276i
BindingDB Entry DOI: 10.7270/Q2SJ1HWH |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50398494
(CHEMBL2177429)Show SMILES C[C@H](C(=O)NCc1ccc(nc1N1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |r| Show InChI InChI=1S/C23H28F4N4O3S/c1-14-8-10-31(11-9-14)21-17(5-7-20(29-21)23(25,26)27)13-28-22(32)15(2)16-4-6-19(18(24)12-16)30-35(3,33)34/h4-7,12,14-15,30H,8-11,13H2,1-3H3,(H,28,32)/t15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human TRPV1 expressed in CHO cells assessed as as inhibition of capsaicin-induced calcium uptake incubated for 5 m... |
Eur J Med Chem 182: (2019)
Article DOI: 10.1016/j.ejmech.2019.111634
BindingDB Entry DOI: 10.7270/Q2765JR7 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50247742
(CHEMBL509154 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)Show SMILES C[C@@H]1C[C@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]2C=C(COC(=O)Cc4ccc(NS(C)(=O)=O)c(F)c4)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)C(C)=C |r,t:18,42,TLB:6:5:15:3.2.1,THB:4:5:15:3.2.1| Show InChI InChI=1S/C37H40FNO9S/c1-21(2)35-17-23(4)37-27(33(35)46-36(47-35,48-37)19-24-9-7-6-8-10-24)14-26(18-34(42)30(37)13-22(3)32(34)41)20-45-31(40)16-25-11-12-29(28(38)15-25)39-49(5,43)44/h6-15,23,27,30,33,39,42H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35+,36?,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.45 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 receptor expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem 17: 690-8 (2009)
Article DOI: 10.1016/j.bmc.2008.11.085
BindingDB Entry DOI: 10.7270/Q2CJ8FCW |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50473853
(CHEMBL332105)Show SMILES COc1cc(CNC(=O)C2CC2(C)CCCC(C)CCCC(C)CCCC(C)C)ccc1O Show InChI InChI=1S/C29H49NO3/c1-21(2)10-7-11-22(3)12-8-13-23(4)14-9-17-29(5)19-25(29)28(32)30-20-24-15-16-26(31)27(18-24)33-6/h15-16,18,21-23,25,31H,7-14,17,19-20H2,1-6H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Istituto per la Chimica di Molecole di Interesse Biologico
Curated by ChEMBL
| Assay Description
Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre... |
J Med Chem 45: 3739-45 (2002)
Article DOI: 10.1021/jm020844o
BindingDB Entry DOI: 10.7270/Q23F4SDF |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196351
(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)Show InChI InChI=1S/C20H26N2O2S/c1-20(2,3)16-8-5-14(6-9-16)12-21-19(25)22-13-15-7-10-17(23)18(11-15)24-4/h5-11,23H,12-13H2,1-4H3,(H2,21,22,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake |
Bioorg Med Chem Lett 17: 214-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.059
BindingDB Entry DOI: 10.7270/Q27D2TSX |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50415875
(CHEMBL1097704)Show InChI InChI=1S/C14H17NO4/c1-18-13-10-11(2-4-12(13)16)3-5-14(17)15-6-8-19-9-7-15/h2-5,10,16H,6-9H2,1H3/b5-3+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a |
Universidad de Antioquia
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu... |
Bioorg Med Chem 18: 3299-306 (2010)
Article DOI: 10.1016/j.bmc.2010.03.013
BindingDB Entry DOI: 10.7270/Q24M95RD |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50415876
(CHEMBL1096703)Show InChI InChI=1S/C14H17NO3S/c1-18-13-10-11(2-4-12(13)16)3-5-14(17)15-6-8-19-9-7-15/h2-5,10,16H,6-9H2,1H3/b5-3+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a |
Universidad de Antioquia
Curated by ChEMBL
| Assay Description
Antagonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as inhibition of capsaicin-induced intracellular calciu... |
Bioorg Med Chem 18: 3299-306 (2010)
Article DOI: 10.1016/j.bmc.2010.03.013
BindingDB Entry DOI: 10.7270/Q24M95RD |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20461
((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)Show InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a |
Universidad de Antioquia
Curated by ChEMBL
| Assay Description
Agonist activity at human TRPV1 expressed in tetracycline-stimulated HEK293 cells assessed as increase in intracellular calcium levels by fluorimetri... |
Bioorg Med Chem 18: 3299-306 (2010)
Article DOI: 10.1016/j.bmc.2010.03.013
BindingDB Entry DOI: 10.7270/Q24M95RD |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196351
(1-(4-tert-Butyl-benzyl)-3-(4-hydroxy-3-methoxy-ben...)Show InChI InChI=1S/C20H26N2O2S/c1-20(2,3)16-8-5-14(6-9-16)12-21-19(25)22-13-15-7-10-17(23)18(11-15)24-4/h5-11,23H,12-13H2,1-4H3,(H2,21,22,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as calcium uptake |
Bioorg Med Chem Lett 22: 5227-31 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.059
BindingDB Entry DOI: 10.7270/Q2NS0VZB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196343
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1O Show InChI InChI=1S/C28H40N2O4S/c1-27(2,3)22-11-8-19(9-12-22)14-21(18-34-25(32)28(4,5)6)17-30-26(35)29-16-20-10-13-23(31)24(15-20)33-7/h8-13,15,21,31H,14,16-18H2,1-7H3,(H2,29,30,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake |
Bioorg Med Chem Lett 17: 214-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.059
BindingDB Entry DOI: 10.7270/Q27D2TSX |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50566158
(CHEMBL4789932)Show SMILES CCCN(CCC)c1nc(ccc1CNC(=O)Nc1cccc2c1cc[nH]c2=O)C(F)(F)F | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Agonist activity at human TRPV1 expressed in CHO cells assessed as stimulation of calcium uptake by 45Ca2+ uptake assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00982
BindingDB Entry DOI: 10.7270/Q2X06BSQ |
More data for this
Ligand-Target Pair | |
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