Compile Data Set for Download or QSAR

Found 186 hits of ec50 data for polymerid = 2154,4221,49000039,7883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.525	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.530	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098525 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210089 ((R)-2-(8-methoxymethyl-benzo[1,2-b;4,5-b']difuran-...) Show SMILES COCc1c2ccoc2c(C[C@@H](C)N)c2ccoc12 Show InChI InChI=1S/C15H17NO3/c1-9(16)7-12-10-3-5-19-15(10)13(8-17-2)11-4-6-18-14(11)12/h3-6,9H,7-8,16H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098530 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210083 (CHEMBL232995 | [8-((R)-2-amino-propyl)-2,3,6,7-tet...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(COCC(=O)Oc2ccccc2)c2CCOc12 Show InChI InChI=1S/C22H25NO5/c1-14(23)11-18-16-7-9-27-22(16)19(17-8-10-26-21(17)18)12-25-13-20(24)28-15-5-3-2-4-6-15/h2-6,14H,7-13,23H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.38	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50271485 (2-(4-Bromo-3,6,7,8-tetrahydro-2H-furo[2,3-g]chrome...) Show SMILES NCCc1c2OCCc2c(Br)c2OCCCc12 Show InChI InChI=1S/C13H16BrNO2/c14-11-10-4-7-17-12(10)9(3-5-15)8-2-1-6-16-13(8)11/h1-7,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.40	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested for its ability to activate phospholipase C by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptor				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat 5HT2A receptor assessed as 5HT-stimulated IP3 accumulation				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098536 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210078 ((R)-2-(8-methoxymethyl-2,3,6,7-tetrahydro-benzo[1,...) Show SMILES COCc1c2CCOc2c(C[C@@H](C)N)c2CCOc12 Show InChI InChI=1S/C15H21NO3/c1-9(16)7-12-10-3-5-19-15(10)13(8-17-2)11-4-6-18-14(11)12/h9H,3-8,16H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50271489 (1-(4-Bromo-7,8-dihydro-6H-furo[2,3-g]chromen-9-yl)...) Show SMILES CC(N)Cc1c2CCCOc2c(Br)c2ccoc12 Show InChI InChI=1S/C14H16BrNO2/c1-8(16)7-11-9-3-2-5-17-14(9)12(15)10-4-6-18-13(10)11/h4,6,8H,2-3,5,7,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Functional potency at the rat 5-hydroxytryptamine 2A receptor as effective concentration EC50 for stimulating Phosphoinositide accumulation				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210084 ((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...) Show SMILES C[C@@H](N)Cc1c2ccoc2c(Cc2nc(C)no2)c2ccoc12 Show InChI InChI=1S/C17H17N3O3/c1-9(18)7-13-11-3-5-22-17(11)14(12-4-6-21-16(12)13)8-15-19-10(2)20-23-15/h3-6,9H,7-8,18H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16.9	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50133231 ((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...) Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	17.8	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194747 (((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3/t6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of phospholipase C-mediated IP production				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50118579 ((2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,...) Show SMILES C[C@H]1C[C@H](C)N1C(=O)[C@H]1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13-,15+,19?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Functional potency at the rat 5-hydroxytryptamine 2A receptor as effective concentration EC50 for stimulating Phosphoinositide accumulation				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098526 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM50538100 (CHEMBL4648350) Show SMILES CNCCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-12-6-5-8-7-13-9-3-2-4-10(14)11(8)9/h2-4,7,12-14H,5-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Mus musculus (Mouse))	BDBM50538100 (CHEMBL4648350) Show SMILES CNCCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C11H14N2O/c1-12-6-5-8-7-13-9-3-2-4-10(14)11(8)9/h2-4,7,12-14H,5-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at mouse 5-HT2A receptor expressed in Flp-In T-REx 293 cells assessed as induction of Gq-mediated calcium flux incubated for 1 hr by...				J Nat Prod 83: 461-467 (2020) Article DOI: 10.1021/acs.jnatprod.9b01061 BindingDB Entry DOI: 10.7270/Q2RX9GM1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50271486 (1-(4-Bromo-3,6,7,8-tetrahydro-2H-furo[2,3-g]chrome...) Show SMILES CC(N)Cc1c2OCCc2c(Br)c2OCCCc12 Show InChI InChI=1S/C14H18BrNO2/c1-8(16)7-11-9-3-2-5-17-14(9)12(15)10-4-6-18-13(10)11/h8H,2-7,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50133231 ((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...) Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50064708 ((R)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine ...) Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1Br |r| Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Serotonin 5-HT2A receptor-mediated intracellular calcium [Ca2+] mobilization in rat A7r5 cells				J Med Chem 47: 6034-41 (2004) Article DOI: 10.1021/jm040082s BindingDB Entry DOI: 10.7270/Q2R78DQ8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210092 (3-[8-((R)-2-amino-propyl)-2,3,6,7-tetrahydro-benzo...) Show SMILES COC(=O)CCc1c2CCOc2c(C[C@@H](C)N)c2CCOc12 Show InChI InChI=1S/C17H23NO4/c1-10(18)9-14-13-6-8-21-16(13)11(3-4-15(19)20-2)12-5-7-22-17(12)14/h10H,3-9,18H2,1-2H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005267 (2,5-dimethoxy-4-bromophenethylamine | 2-(4-Bromo-2...) Show SMILES COc1cc(CCN)c(OC)cc1Br Show InChI InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of phospholipase C-mediated IP production				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50133231 ((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...) Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	27.7	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description In vitro relative agonist activity against 5-hydroxytryptamine 2A using PI assay in rat vascular smooth muscle cells				J Med Chem 46: 4188-95 (2003) Article DOI: 10.1021/jm030205t BindingDB Entry DOI: 10.7270/Q2Z320C1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098535 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210081 ((1R,2R)-2-amino-1-(8-bromo-2,3,6,7-tetrahydro-benz...) Show SMILES C[C@@H](N)[C@H](O)c1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO3/c1-6(15)11(16)9-7-2-4-18-13(7)10(14)8-3-5-17-12(8)9/h6,11,16H,2-5,15H2,1H3/t6-,11+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32.7	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210093 (CHEMBL393077 | [8-((R)-2-amino-propyl)-benzo[1,2-b...) Show SMILES C[C@@H](N)Cc1c2ccoc2c(CO)c2ccoc12 Show InChI InChI=1S/C14H15NO3/c1-8(15)6-11-9-2-4-18-14(9)12(7-16)10-3-5-17-13(10)11/h2-5,8,16H,6-7,15H2,1H3/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098534 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194752 ((+/-)-(4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)m...) Show SMILES COc1cc(Br)c(OC)c2CC(CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of phospholipase C-mediated IP production				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50014219 (2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine | ...) Show SMILES COc1ccc2[nH]cc(CC(C)N)c2c1 Show InChI InChI=1S/C12H16N2O/c1-8(13)5-9-7-14-12-4-3-10(15-2)6-11(9)12/h3-4,6-8,14H,5,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50210085 ((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Cc2nc(C)no2)c2CCOc12 Show InChI InChI=1S/C17H21N3O3/c1-9(18)7-13-11-3-5-22-17(11)14(12-4-6-21-16(12)13)8-15-19-10(2)20-23-15/h9H,3-8,18H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	49.2	n/a	n/a	n/a	n/a
Alcon Research, Ltd Curated by ChEMBL					Assay Description Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT				Bioorg Med Chem Lett 17: 2998-3002 (2007) Article DOI: 10.1016/j.bmcl.2007.03.073 BindingDB Entry DOI: 10.7270/Q2KS6R7B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180252 ((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...) Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1 Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55.8	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description The receptor (5-hydroxytryptamine 2A ) mediated mobilization of intracellular calcium [Ca2+] was studied in rat smooth muscle cells				J Med Chem 46: 4188-95 (2003) Article DOI: 10.1021/jm030205t BindingDB Entry DOI: 10.7270/Q2Z320C1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM28582 (1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...) Show SMILES COc1cc(CC(C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at rat 5-HT2A receptor expressed in African clawed frog oocytes assessed as increase in current amplitude				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180258 (1-((S)-2-aminopropyl)-7-fluoro-1H-indazol-6-ol | C...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)c(F)c12 Show InChI InChI=1S/C10H12FN3O/c1-6(12)5-14-10-7(4-13-14)2-3-8(15)9(10)11/h2-4,6,15H,5,12H2,1H3/t6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50014945 (3-(2-aminopropyl)-1H-indol-5-ol | CHEMBL275854 | a...) Show SMILES CC(N)Cc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180255 (1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)c(Cl)c12 Show InChI InChI=1S/C10H12ClN3O/c1-6(12)5-14-10-7(4-13-14)2-3-8(15)9(10)11/h2-4,6,15H,5,12H2,1H3/t6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Serotonin 5-HT2A receptor-mediated intracellular calcium [Ca2+] mobilization in rat A7r5 cells				J Med Chem 47: 6034-41 (2004) Article DOI: 10.1021/jm040082s BindingDB Entry DOI: 10.7270/Q2R78DQ8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50038370 (2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...) Show SMILES COc1cc(c(OC)cc1CC(C)N)C(F)(F)F Show InChI InChI=1S/C12H16F3NO2/c1-7(16)4-8-5-11(18-3)9(12(13,14)15)6-10(8)17-2/h5-7H,4,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	68.4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair

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