BindingDB PrimarySearch

Found 4972 hits of ec50 data for polymerid = 2209,50001093,50004898
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349812 (CHEMBL1813010) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.000100	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349809 (CHEMBL1813006) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.000200	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349808 (CHEMBL1813005) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.000300	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349807 (CHEMBL1813003) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.00150	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349813 (CHEMBL1813011) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0180	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50450236 (Efatutazone) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0380	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 26: 5079-5098 (2018) Article DOI: 10.1016/j.bmc.2018.09.006 BindingDB Entry DOI: 10.7270/Q2J968XC
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349811 (CHEMBL1813008) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471968 (CHEMBL358379) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay				Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471968 (CHEMBL358379) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50004753 (CHEMBL2282517) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50004753 (CHEMBL2282517) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28783 ((3E)-3-(ethoxyimino)-2-({4-[2-(5-methyl-2-phenyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471982 (CHEMBL147384) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.126	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471982 (CHEMBL147384) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	0.126	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay				Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28780 ((3E)-3-(butoxyimino)-2-({4-[2-(5-methyl-2-phenyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50151001 ((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assay				J Med Chem 47: 4118-27 (2004) Article DOI: 10.1021/jm030631e BindingDB Entry DOI: 10.7270/Q2DR2TZ5
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471980 (CHEMBL147095) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.245	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50013727 (CHEBI:79990 \| CHEMBL410478 \| GW409544) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at GAL4-fused human PPARgamma LBD				Bioorg Med Chem Lett 28: 2717-2722 (2018) Article DOI: 10.1016/j.bmcl.2018.03.010 BindingDB Entry DOI: 10.7270/Q24F1TCK
University of Oklahoma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50151001 ((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
USDA-ARS Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma				Bioorg Med Chem 16: 3800-8 (2008) Article DOI: 10.1016/j.bmc.2008.01.051 BindingDB Entry DOI: 10.7270/Q2WW7JKJ
USDA-ARS Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472035 (CHEMBL2112870) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.282	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a...				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28779 ((3E)-2-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)e...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472041 (CHEMBL147770) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.302	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a...				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28782 ((3E)-3-(methoxyimino)-2-({4-[2-(5-methyl-2-phenyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article	n/a	n/a	n/a	n/a	0.339	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay				Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.339	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a...				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.339	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.339	n/a	n/a	n/a	n/a
Rikkyo University Curated by ChEMBL					Assay Description Transactivation of PPARgamma assessed as induction of alkaline phosphatase activity				Bioorg Med Chem Lett 20: 3344-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.031 BindingDB Entry DOI: 10.7270/Q2C53N33
Rikkyo University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Agonist activity for Human PPAR gamma receptor in transcriptional activation assay				J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT
Glaxo Wellcome Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50004754 (CHEMBL2282523) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximal reporter activity against human Peroxisome proliferator activated receptor gamma Gal4 chimeric in transiently transfected CV-1 cells by funct...				Bioorg Med Chem Lett 11: 3111-3 (2001) BindingDB Entry DOI: 10.7270/Q2B27TKM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50004754 (CHEMBL2282523) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...				Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Activation of peroxisome proliferator activated receptor gamma measured by induction of 50% of maximum alkaline phosphatase activity, transfection as...				J Med Chem 41: 5020-36 (1999) Checked by Author Article DOI: 10.1021/jm9804127 BindingDB Entry DOI: 10.7270/Q20K2B28
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	n/a	n/a	0.350	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Agonist activity for murine PPAR gamma receptor in transcriptional activation assay				J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT
Glaxo Wellcome Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.350	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Compound was tested functionally in vitro for inducing 50% of the maximum alkaline phosphatase activity (Transactivation) against murine Peroxisome p...				J Med Chem 41: 5020-36 (1999) Checked by Author Article DOI: 10.1021/jm9804127 BindingDB Entry DOI: 10.7270/Q20K2B28
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28781 ((3E)-3-[(cyclopropylmethoxy)imino]-2-({4-[2-(5-met...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.360	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50093472 (CHEMBL3585575) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a
Universitat Rovira i Virgili (URV) Curated by ChEMBL					Assay Description Activity at PPARgamma (unknown origin) assessed as transactivation activity by reporter gene assay				J Med Chem 58: 5381-94 (2015) Article DOI: 10.1021/jm501155f BindingDB Entry DOI: 10.7270/Q2K07601
Universitat Rovira i Virgili (URV) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50093472 (CHEMBL3585575) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a
Universit£ Degli Studi di Bari "Aldo Moro" Curated by ChEMBL					Assay Description Transactivation of PPARgamma (unknown origin)				Eur J Med Chem 176: 326-342 (2019) Article DOI: 10.1016/j.ejmech.2019.05.012 BindingDB Entry DOI: 10.7270/Q2HQ43BR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50135450 ((2E,4E,6Z)-7-[4-(2,2-Difluoro-ethoxy)-2'-fluoro-5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro agonistic activity against RXR alpha in CV-1 cells				Bioorg Med Chem Lett 13: 4071-5 (2003) BindingDB Entry DOI: 10.7270/Q2V987GP
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50557786 (CHEMBL4776913) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.410	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at full-length PPARgamma (unknown origin) expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472011 (CHEMBL148300) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.427	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description -log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50106109 (4-Isocyanato-benzoic acid 2-((2,4-bis-trifluoromet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonistic transcriptional activity in CV-1 cells expressing Gal4-PPAR gamma chimera				Bioorg Med Chem Lett 11: 2959-62 (2001) BindingDB Entry DOI: 10.7270/Q2V69HWQ
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28784 ((3E)-3-{[(4-fluorophenyl)methoxy]imino}-2-({4-[2-(...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.540	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28778 ((3E)-2-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)e...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a
LG Life Sciences					Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...				Bioorg Med Chem Lett 17: 937-41 (2007) Article DOI: 10.1016/j.bmcl.2006.11.050 BindingDB Entry DOI: 10.7270/Q2057D8J
LG Life Sciences					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472019 (CHEMBL148668) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.575	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator a...				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM614895 (A7-54 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4-(1,1,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent									US Patent US10173996 (2019) BindingDB Entry DOI: 10.7270/Q2TT4W2H
Celgene Quanticel Research, Inc. US Patent					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085044 ((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(5-methyl-2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assay				Bioorg Med Chem Lett 17: 2312-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.060 BindingDB Entry DOI: 10.7270/Q21N80ST
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50349816 (CHEMBL1813009) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 3103-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.020 BindingDB Entry DOI: 10.7270/Q2ZC837H
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471953 (CHEMBL356382) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.603	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Tested functionally in vitro for inducing 50% of the maximum alkaline phosphate activity (Transactivation) against Peroxisome proliferator activated ...				J Med Chem 41: 5037-54 (1998) Article DOI: 10.1021/jm980413z BindingDB Entry DOI: 10.7270/Q2J38W9F
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50471953 (CHEMBL356382) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	0.603	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay				Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50085046 (2-((S)-1-carboxy-2-{4-[2-(5-methyl-2-phenyl-oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.617	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description -log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
Glaxo Wellcome Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair

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