Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22376 ((3aS,6aR)-4-cyclohexyl-5-[(4E)-oct-4-en-4-yl]-N-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22391 ((3aS,6aR)-N-(2,3-dimethylphenyl)-5-hexyl-4-phenyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22381 ((3aS,6aR)-5-[(6E)-dodec-6-en-6-yl]-N,4-diphenyl-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22375 ((3aS,6aR)-4-butyl-5-[(4E)-oct-4-en-4-yl]-N-phenyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418303 (CHEMBL1765959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 31.6 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418304 (CHEMBL1765953) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 39.8 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22385 ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 39.8 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22385 ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22373 ((3aS,6aR)-5-[(4E)-oct-4-en-4-yl]-N,4-diphenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418308 (CHEMBL1765933) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418307 (CHEMBL1765934) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418306 (CHEMBL1765955) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418305 (CHEMBL1765960) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418309 (CHEMBL1765956) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418310 (CHEMBL1765962) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 79.4 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418311 (CHEMBL1765931) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 79.4 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM28650 (ethyl 2-[(2-{[(4-ethylphenyl)carbamoyl]methyl}-1-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Scripps Florida | Assay Description The assay was to monitor the SF-1 activation state via co-transfection of CHO-K1 cells with a plasmid encoding a Gal4-SF-1 chimerical transcription f... | Bioorg Med Chem Lett 18: 2628-32 (2008) Article DOI: 10.1016/j.bmcl.2008.03.027 BindingDB Entry DOI: 10.7270/Q2125R0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22388 ((3aS,6aR)-N,4,5-triphenyl-1,2,3,3a,6,6a-hexahydrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418313 (CHEMBL1765945) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39548 ((2-phenyl-1,3-thiazol-4-yl)methyl 1-methylpyrrole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 129 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22379 ((3aS,6aR)-4-(naphthalen-2-yl)-5-[(4E)-oct-4-en-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22383 ((3aS,6aR)-5-(decan-2-yl)-N,4-diphenyl-1,2,3,3a,6,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22382 ((3aS,6aR)-5-(hexan-2-yl)-N,4-diphenyl-1,2,3,3a,6,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39480 (2-(1-tert-butyl-4-keto-pyrazolo[3,4-d]pyrimidin-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 138 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q23T9FMP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39527 (MLS000070707 | N-(6-ethoxy-1,3-benzothiazol-2-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22378 ((3aS,6aR)-4-(3-methoxyphenyl)-5-[(4E)-oct-4-en-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418314 (CHEMBL1765954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22373 ((3aS,6aR)-5-[(4E)-oct-4-en-4-yl]-N,4-diphenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418300 (CHEMBL1765941) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418315 (CHEMBL1765936) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39428 (5-Methyl-furan-2-carboxylic acid (5-benzyl-thiazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 168 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q23T9FMP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22377 ((3aS,6aR)-4-(4-bromophenyl)-5-[(4E)-oct-4-en-4-yl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM22386 ((3aS,6aR)-5-cyclohexyl-N,4-diphenyl-1,2,3,3a,6,6a-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human SF1 and a peptide der... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39426 (7-amino-3-phenyl-6-pyrazolo[1,5-a]pyrimidinecarbox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 183 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q23T9FMP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM28649 (ethyl 2-[(2-{[(4-ethoxyphenyl)carbamoyl]methyl}-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Scripps Florida | Assay Description The assay was to monitor the SF-1 activation state via co-transfection of CHO-K1 cells with a plasmid encoding a Gal4-SF-1 chimerical transcription f... | Bioorg Med Chem Lett 18: 2628-32 (2008) Article DOI: 10.1016/j.bmcl.2008.03.027 BindingDB Entry DOI: 10.7270/Q2125R0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39531 (8-methyl-2-phenyl-imidazo[1,2-a]pyridine | 8-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM28648 (ethyl 2-{[1-oxo-2-({[4-(trifluoromethoxy)phenyl]ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Scripps Florida | Assay Description The assay was to monitor the SF-1 activation state via co-transfection of CHO-K1 cells with a plasmid encoding a Gal4-SF-1 chimerical transcription f... | Bioorg Med Chem Lett 18: 2628-32 (2008) Article DOI: 10.1016/j.bmcl.2008.03.027 BindingDB Entry DOI: 10.7270/Q2125R0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418320 (CHEMBL1765927) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418319 (CHEMBL1765930) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418318 (CHEMBL1765942) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418316 (CHEMBL1765966) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM28647 (ethyl 2-[(2-{[(4-methoxyphenyl)carbamoyl]methyl}-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Scripps Florida | Assay Description The assay was to monitor the SF-1 activation state via co-transfection of CHO-K1 cells with a plasmid encoding a Gal4-SF-1 chimerical transcription f... | Bioorg Med Chem Lett 18: 2628-32 (2008) Article DOI: 10.1016/j.bmcl.2008.03.027 BindingDB Entry DOI: 10.7270/Q2125R0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418317 (CHEMBL1765950) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39543 (3-(3-methoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 226 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39565 (2-(2-chlorophenyl)-5-(4-chlorophenyl)-1,3,4-oxadia...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 233 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418302 (CHEMBL1765929) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418321 (CHEMBL1765963) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM50418322 (CHEMBL1765948) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39534 (1-azepanyl-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 252 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroidogenic factor 1 (Homo sapiens (Human)) | BDBM39537 (MLS000077996 | N-[5-(1-adamantyl)-1,3,4-thiadiazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 257 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2028PXQ | |||||||||||
More data for this Ligand-Target Pair |
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