Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324346 (CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324324 (2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324331 (2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324323 (2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324347 (CHEMBL1215153 | Isopropyl-[6-piperazin-1-yl-4-(1H-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324322 (4-(2-cyclohexylaminopyridin-4-yl)-6-(piperazin-1-y...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 115 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324329 (2'-Cyclopentylamino-6-piperazin-1-yl[2,4']bipyridi...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 202 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324348 (6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 234 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324344 (CHEMBL1215360 | Cyclohexyl-(6-piperazin-1-yl-4-tri...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 342 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324332 (2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 378 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324333 (2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 428 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324326 (4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 438 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324328 (2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 478 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324345 (CHEMBL1215361 | Cyclohexyl-(4-difluoromethyl-6-pip...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 568 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324327 (2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 674 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324337 (2'-Cyclohexylamino-6-((R)-3-methylpiperazin-1-yl)[...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 679 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324334 (CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 704 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324340 (2'-Cyclohexylamino-6-(4-methylpiperazin-1-yl)[2,4'...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 752 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324338 (2'-Cyclohexylamino-6-((S)-3-methylpiperazin-1-yl)[...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 831 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324342 (2'-Cyclohexylamino-6-(3,3-dimethylpiperazin-1-yl)[...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324336 (2'-Cyclohexylamino-6-((S)-pyrrolidin-3-ylamino)[2,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324335 (2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324325 (6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324339 (3-Amino-2''-cyclohexylamino-3,4,5,6-tetrahydro-2H-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324341 (Aminomethyl-2''-cyclohexylamino-3,4,5,6-tetrahydro...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324321 (6-(2-Cyclohexylaminopyridin-4-yl)-4-piperazin-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324330 (2'-Ethylamino-6-piperazin-1-yl[2,4']bipyridinyl-4-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export | J Med Chem 53: 5422-38 (2010) Article DOI: 10.1021/jm100076w BindingDB Entry DOI: 10.7270/Q2P84C2J | |||||||||||
More data for this Ligand-Target Pair |