Compile Data Set for Download or QSAR

Found 4 hits of ec50 data for polymerid = 49000307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50283421 (((E)-Azacyclotridec-1-en-2-yl)-(2,2-diphenyl-penty...) Show SMILES CCCC(CNC1=NCCCCCCCCCCC1)(c1ccccc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C29H42N2/c1-2-23-29(26-18-12-10-13-19-26,27-20-14-11-15-21-27)25-31-28-22-16-8-6-4-3-5-7-9-17-24-30-28/h10-15,18-21H,2-9,16-17,22-25H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding of [3H]-nitrendipine to calcium channel in rat heart membranes				Bioorg Med Chem Lett 4: 351-354 (1994) Article DOI: 10.1016/S0960-894X(01)80143-8 BindingDB Entry DOI: 10.7270/Q2R78F5H
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50283420 (((E)-Azacyclotridec-1-en-2-yl)-((1S,2S)-2-phenyl-c...) Show SMILES C1C[C@H](N=C2CCCCCCCCCCCN2)[C@@H](C1)c1ccccc1 |w:4.16| Show InChI InChI=1S/C23H36N2/c1-2-4-6-11-18-23(24-19-12-7-5-3-1)25-22-17-13-16-21(22)20-14-9-8-10-15-20/h8-10,14-15,21-22H,1-7,11-13,16-19H2,(H,24,25)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding of [3H]-nitrendipine to calcium channel in rat heart membranes				Bioorg Med Chem Lett 4: 351-354 (1994) Article DOI: 10.1016/S0960-894X(01)80143-8 BindingDB Entry DOI: 10.7270/Q2R78F5H
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50283420 (((E)-Azacyclotridec-1-en-2-yl)-((1S,2S)-2-phenyl-c...) Show SMILES C1C[C@H](N=C2CCCCCCCCCCCN2)[C@@H](C1)c1ccccc1 |w:4.16| Show InChI InChI=1S/C23H36N2/c1-2-4-6-11-18-23(24-19-12-7-5-3-1)25-22-17-13-16-21(22)20-14-9-8-10-15-20/h8-10,14-15,21-22H,1-7,11-13,16-19H2,(H,24,25)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding of [3H]-nitrendipine to calcium channel in rat heart membranes was determined				Bioorg Med Chem Lett 4: 351-354 (1994) Article DOI: 10.1016/S0960-894X(01)80143-8 BindingDB Entry DOI: 10.7270/Q2R78F5H
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50516235 (CHEMBL4563408) Show SMILES FC(F)Oc1ccc(NC(=O)NC2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1 Show InChI InChI=1S/C29H24Cl2F2N8O2/c30-17-5-8-20(9-6-17)41-25(21-3-1-2-4-22(21)31)39-24-26(35-16-36-27(24)41)40-13-11-18(12-14-40)37-29(42)38-19-7-10-23(34-15-19)43-28(32)33/h1-10,15-16,18,28H,11-14H2,(H2,37,38,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Displacement of [3H]nitrendipine from rat brain Cav1.2 dihydropyridine site after 90 mins by scintillation counting analysis				J Med Chem 62: 6330-6345 (2019) Article DOI: 10.1021/acs.jmedchem.9b00727 BindingDB Entry DOI: 10.7270/Q24F1V3D
					More data for this Ligand-Target Pair