BindingDB PrimarySearch

Found 42 hits of ec50 data for polymerid = 49000610
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50316377 ((R,S)-6-(2-amino-2-carboxyethyl)-3-hydroxypyridazi...) Show SMILES NC(Cc1ccc(=O)[nH][n+]1[O-])C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	258	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50316377 ((R,S)-6-(2-amino-2-carboxyethyl)-3-hydroxypyridazi...) Show SMILES NC(Cc1ccc(=O)[nH][n+]1[O-])C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50316376 ((S)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)pro...) Show SMILES Cc1onc(C(O)=O)c1C[C@H](N)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	382	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50330419 (CHEMBL1277095 \| N,N'-(nonane-1,9-diyl)dipropane-2-...) Show SMILES CC(C)S(=O)(=O)NCCCCCCCCCNS(=O)(=O)C(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GluR1 expressed in HEK cells				J Med Chem 53: 7271-9 (2010) Article DOI: 10.1021/jm1000419 BindingDB Entry DOI: 10.7270/Q2W0965T
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50330417 (CHEMBL1277094 \| N,N'-(octane-1,8-diyl)dipropane-2-...) Show SMILES CC(C)S(=O)(=O)NCCCCCCCCNS(=O)(=O)C(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GluR1 expressed in HEK cells				J Med Chem 53: 7271-9 (2010) Article DOI: 10.1021/jm1000419 BindingDB Entry DOI: 10.7270/Q2W0965T
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50192229 (3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50192229 (3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on 10 uM glutamate-indu...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50330418 (CHEMBL1276246 \| N,N'-(heptane-1,7-diyl)dipropane-2...) Show SMILES CC(C)S(=O)(=O)NCCCCCCCNS(=O)(=O)C(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GluR1 expressed in HEK cells				J Med Chem 53: 7271-9 (2010) Article DOI: 10.1021/jm1000419 BindingDB Entry DOI: 10.7270/Q2W0965T
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) Show SMILES NC(Cc1o[nH]c(=O)c1Cl)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at GluA1 receptor				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50252922 ((S)-1-(2'-Amino-2'-carboxyethyl)thieno[3,2-d]pyrim...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Agonist activity at cyclothiazide-desensitized human flip iGluR1 expressed in CHO-K1 cells by whole cell patch-clamp method				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50126764 ((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o)				J Med Chem 46: 1350-8 (2003) Article DOI: 10.1021/jm0204441 BindingDB Entry DOI: 10.7270/Q2902346
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) Show SMILES NC(Cc1o[nH]c(=O)c1Cl)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50126761 ((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...) Show SMILES CC(C)(C)c1s[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o)				J Med Chem 46: 1350-8 (2003) Article DOI: 10.1021/jm0204441 BindingDB Entry DOI: 10.7270/Q2902346
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50126761 ((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...) Show SMILES CC(C)(C)c1s[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GluA1 (unknown origin)				J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50316375 (CHEMBL1097939 \| LY-404187 \| N-[2-(4'-cyanobiphenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at human recombinant GluA1 receptor flip isoform expressed in HEK293 cells assessed as effect on glutamate-induced calcium flux by Fluo-4/AM...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50094024 ((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GluR1 expressed in HEK cells				J Med Chem 53: 7271-9 (2010) Article DOI: 10.1021/jm1000419 BindingDB Entry DOI: 10.7270/Q2W0965T
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	7.51E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50192229 (3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on 10 uM glutamate-indu...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) Show SMILES NC(Cc1o[nH]c(=O)c1Br)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) Show SMILES NC(Cc1o[nH]c(=O)c1Br)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50252920 ((S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Agonist activity at cyclothiazide-desensitized human flip iGluR1 expressed in CHO-K1 cells by whole cell patch-clamp method				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50192229 (3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at human recombinant GluA1 receptor flip isoform expressed in HEK293 cells assessed as effect on glutamate-induced calcium flux by Fluo-4/AM...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50330411 (1,2,3,7,8,11a-Hexahydro-6,9,11-trioxa-3a-aza-cyclo...) Show SMILES O=C1N2CCCC2Oc2cc3OCCOc3cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GluR1 expressed in HEK cells				J Med Chem 53: 7271-9 (2010) Article DOI: 10.1021/jm1000419 BindingDB Entry DOI: 10.7270/Q2W0965T
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50126763 ((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...) Show SMILES CC(C)(C)c1o[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o)				J Med Chem 46: 1350-8 (2003) Article DOI: 10.1021/jm0204441 BindingDB Entry DOI: 10.7270/Q2902346
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50048386 (1-(4-aminophenyl)-3-methylcarbamyl-4-methyl-3,4-di...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARP assessed as effect on glutamate/trichlorom...				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Agonist activity at GluA1 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
University of Turin Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Agonist activity at GluA1 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
University of Turin Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GluA1 (unknown origin)				J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.50E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50512943 (CHEMBL4448290) Show SMILES CCn1nc(O)c(CC(N)C(O)=O)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Agonist activity at GluA1 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
University of Turin Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50512946 (CHEMBL4451018) Show SMILES CCCn1nc(O)c(CC(N)C(O)=O)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Agonist activity at GluA1 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
University of Turin Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50059674 ((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...) Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+6	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay				J Med Chem 50: 4177-85 (2007) Article DOI: 10.1021/jm070532r BindingDB Entry DOI: 10.7270/Q29P32F3
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair