Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078513 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the NMDA receptor-ion channel complex was demonstrated by the ability to inhibit the binding of thechannel-blocking agent [3... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50001266 (5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078527 (7,9-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078507 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | n/a | n/a | 2.72E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078519 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078531 (4-Oxo-7-trifluoromethyl-4,5-dihydro-[1,2,4]triazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.18E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078515 (7-Bromo-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356624 (US10214478, Compound NM-008) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078522 (4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356628 (US10214478, Compound NM-009) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356629 (US10214478, Compound NM-011) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.86E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356623 (US10214478, Compound NM-005) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.06E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078517 (7-Nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356622 (US10214478, Compound NM-004) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 8.12E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356630 (US10214478, Compound NM-012) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252360 ((R)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ac...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356621 (US10214478, Compound NM-003) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.54E+4 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356619 (US10214478, Compound NM-001) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.46E+4 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356620 (US10214478, Compound NM-002) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.52E+4 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM356631 (Nitromemantine | US10214478, Compound YQW-036) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin... | US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078510 (8-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.25E+4 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252366 ((R)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-acetic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252363 ((R)-amino-(1-hydroxy-4-methyl-pyrazol-3-yl)-acetic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252434 ((R)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acetic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252428 ((R)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acetic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078530 (4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.20E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078528 (7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078511 (8-Nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078506 (8-Chloro-6-nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50078509 (7-Amino-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universita' di Firenze Curated by ChEMBL | Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ... | J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252427 ((R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252433 ((R,S)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.49E+5 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect... | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50252433 ((R,S)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.52E+5 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology | J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q | |||||||||||
More data for this Ligand-Target Pair |
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