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Compile Data Set for Download or QSAR

Found 96 hits of ec50 data for polymerid = 49000763   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552347
PNG
(CHEMBL4798021)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O
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n/an/an/an/a 98n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552346
PNG
(CHEMBL4777502)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O
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n/an/an/an/a 106n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552348
PNG
(CHEMBL4764083)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O
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n/an/an/an/a 114n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552330
PNG
(CHEMBL4745982)
Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O
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n/an/an/an/a 180n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552342
PNG
(CHEMBL4787053)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F
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n/an/an/an/a 201n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552354
PNG
(CHEMBL4799902)
Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F
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n/an/an/an/a 302n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552349
PNG
(CHEMBL4792152)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
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n/an/an/an/a 372n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552333
PNG
(CHEMBL4760570)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7|
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n/an/an/an/a 377n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552332
PNG
(CHEMBL4797971)
Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7|
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TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552343
PNG
(CHEMBL4746530)
Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F
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TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM17657
PNG
((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Show SMILES N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
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n/an/an/an/a 1.18E+3n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP production

J Med Chem 59: 914-24 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01333
BindingDB Entry DOI: 10.7270/Q2000408
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50552331
PNG
(CHEMBL4795139)
Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22|
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n/an/an/an/a 1.34E+3n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50393322
PNG
(CHEMBL2152119)
Show SMILES O[C@H]1CC[C@@H](CC1)n1ccc2cc(ccc12)-c1ccn2c(CC(F)(F)F)cnc2c1Cl |r,wU:1.0,wD:4.7,(14.04,-34.61,;14.86,-33.31,;14.14,-31.95,;14.97,-30.65,;16.51,-30.72,;17.22,-32.08,;16.4,-33.38,;17.33,-29.42,;16.45,-28.16,;17.37,-26.93,;18.83,-27.43,;20.17,-26.68,;21.49,-27.47,;21.47,-29,;20.12,-29.75,;18.81,-28.97,;22.84,-26.72,;24.16,-27.5,;25.5,-26.75,;25.52,-25.22,;26.68,-24.2,;28.23,-24.21,;29.04,-22.9,;30.58,-22.94,;28.3,-21.54,;29.79,-21.55,;26.08,-22.79,;24.55,-22.93,;24.21,-24.43,;22.86,-25.18,;21.54,-24.38,)|
Show InChI InChI=1S/C23H21ClF3N3O/c24-21-19(8-10-30-17(12-23(25,26)27)13-28-22(21)30)14-1-6-20-15(11-14)7-9-29(20)16-2-4-18(31)5-3-16/h1,6-11,13,16,18,31H,2-5,12H2/t16-,18-
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n/an/an/an/a 5.20E+3n/an/an/an/a



Janssen-Cilag S.A.

Curated by ChEMBL


Assay Description
Agonist activity at human mGlu 7 expressed in HEK293 cells by Ca+2 assay

J Med Chem 55: 2688-701 (2012)


Article DOI: 10.1021/jm201561r
BindingDB Entry DOI: 10.7270/Q2SN0B2B
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50440205
PNG
(CHEMBL2426621)
Show SMILES O=C1CCCc2nc(sc12)C#Cc1ccccc1
Show InChI InChI=1S/C15H11NOS/c17-13-8-4-7-12-15(13)18-14(16-12)10-9-11-5-2-1-3-6-11/h1-3,5-6H,4,7-8H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assay

J Med Chem 56: 7243-59 (2013)


Article DOI: 10.1021/jm400650w
BindingDB Entry DOI: 10.7270/Q2F19152
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50337525
PNG
(7-(phenoxymethyl)chroman-4-one | CHEMBL1682820)
Show SMILES O=C1CCOc2cc(COc3ccccc3)ccc12
Show InChI InChI=1S/C16H14O3/c17-15-8-9-18-16-10-12(6-7-14(15)16)11-19-13-4-2-1-3-5-13/h1-7,10H,8-9,11H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assay

J Med Chem 56: 7243-59 (2013)


Article DOI: 10.1021/jm400650w
BindingDB Entry DOI: 10.7270/Q2F19152
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50064444
PNG
(CHEMBL3401195)
Show SMILES Fc1ccc(cc1)N1CCc2nc(COc3ccccc3)cn2C1=O
Show InChI InChI=1S/C19H16FN3O2/c20-14-6-8-16(9-7-14)22-11-10-18-21-15(12-23(18)19(22)24)13-25-17-4-2-1-3-5-17/h1-9,12H,10-11,13H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation at mGluR7 (unknown origin)

Bioorg Med Chem Lett 25: 1310-7 (2015)


Article DOI: 10.1016/j.bmcl.2015.01.038
BindingDB Entry DOI: 10.7270/Q2057HNQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50353291
PNG
(CHEMBL1830711)
Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1
Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization

J Med Chem 54: 5070-81 (2011)


Article DOI: 10.1021/jm200290z
BindingDB Entry DOI: 10.7270/Q26110P5
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50353290
PNG
(CHEMBL1830707)
Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1
Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization

J Med Chem 54: 5070-81 (2011)


Article DOI: 10.1021/jm200290z
BindingDB Entry DOI: 10.7270/Q26110P5
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50064463
PNG
(CHEMBL3401177)
Show SMILES Fc1ccc(cc1)-n1ccc2nc(COc3ccccc3)cn2c1=O
Show InChI InChI=1S/C19H14FN3O2/c20-14-6-8-16(9-7-14)22-11-10-18-21-15(12-23(18)19(22)24)13-25-17-4-2-1-3-5-17/h1-12H,13H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation at mGluR7 (unknown origin)

Bioorg Med Chem Lett 25: 1310-7 (2015)


Article DOI: 10.1016/j.bmcl.2015.01.038
BindingDB Entry DOI: 10.7270/Q2057HNQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM49388
PNG
(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Show SMILES O=C1CCOc2cc(OCc3ccccc3)ccc12
Show InChI InChI=1S/C16H14O3/c17-15-8-9-18-16-10-13(6-7-14(15)16)19-11-12-4-2-1-3-5-12/h1-7,10H,8-9,11H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assay

J Med Chem 56: 7243-59 (2013)


Article DOI: 10.1021/jm400650w
BindingDB Entry DOI: 10.7270/Q2F19152
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50132507
PNG
(CHEMBL3633943)
Show SMILES CC(=O)N1CCCn2nc(COc3ccccc3)cc12
Show InChI InChI=1S/C15H17N3O2/c1-12(19)17-8-5-9-18-15(17)10-13(16-18)11-20-14-6-3-2-4-7-14/h2-4,6-7,10H,5,8-9,11H2,1H3
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n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
In vitro binding affinity for PPAR-gamma

Bioorg Med Chem Lett 25: 5115-20 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.009
BindingDB Entry DOI: 10.7270/Q2445P80
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50392432
PNG
(CHEMBL2151817)
Show SMILES C[C@@H](NC(=O)c1ccc(OCc2cccc(F)c2)nc1)C(C)(C)C |r|
Show InChI InChI=1S/C19H23FN2O2/c1-13(19(2,3)4)22-18(23)15-8-9-17(21-11-15)24-12-14-6-5-7-16(20)10-14/h5-11,13H,12H2,1-4H3,(H,22,23)/t13-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of mGluR7

Bioorg Med Chem Lett 22: 6481-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.043
BindingDB Entry DOI: 10.7270/Q2KD200S
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50134443
PNG
(CHEMBL3746457)
Show SMILES Fc1ccc(nc1)N1CCn2nc(COc3ccccc3)cc2C1=O
Show InChI InChI=1S/C18H15FN4O2/c19-13-6-7-17(20-11-13)22-8-9-23-16(18(22)24)10-14(21-23)12-25-15-4-2-1-3-5-15/h1-7,10-11H,8-9,12H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis

Bioorg Med Chem Lett 26: 429-34 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.098
BindingDB Entry DOI: 10.7270/Q2SJ1NGS
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50134466
PNG
(CHEMBL3747116)
Show SMILES Fc1ccc(cc1)N1CCn2nc(OCc3ccccc3)cc2C1=O
Show InChI InChI=1S/C19H16FN3O2/c20-15-6-8-16(9-7-15)22-10-11-23-17(19(22)24)12-18(21-23)25-13-14-4-2-1-3-5-14/h1-9,12H,10-11,13H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysis

Bioorg Med Chem Lett 26: 429-34 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.098
BindingDB Entry DOI: 10.7270/Q2SJ1NGS
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50353292
PNG
(CHEMBL1830698)
Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12
Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization

J Med Chem 54: 5070-81 (2011)


Article DOI: 10.1021/jm200290z
BindingDB Entry DOI: 10.7270/Q26110P5
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50440185
PNG
(CHEMBL2426616)
Show SMILES CN1CCc2nc(COc3ccccc3)sc2C1=O
Show InChI InChI=1S/C14H14N2O2S/c1-16-8-7-11-13(14(16)17)19-12(15-11)9-18-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
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n/an/an/an/a>1.00E+4n/an/an/an/a



Janssen Research and Development

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assay

J Med Chem 56: 7243-59 (2013)


Article DOI: 10.1021/jm400650w
BindingDB Entry DOI: 10.7270/Q2F19152
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255294
PNG
(CHEMBL4090312)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(N)cc1)C(O)=O |r|
Show InChI InChI=1S/C11H17N2O5P/c12-8-3-1-7(2-4-8)11(16)19(17,18)6-5-9(13)10(14)15/h1-4,9,11,16H,5-6,12-13H2,(H,14,15)(H,17,18)/t9-,11?/m0/s1
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n/an/an/an/a 1.16E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50204257
PNG
(CHEMBL3947221)
Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)([C@H](OCc1ccc(Cl)c(Cl)c1)[C@H]2O)C(O)=O |r|
Show InChI InChI=1S/C15H15Cl2NO6/c16-6-2-1-5(3-7(6)17)4-24-12-11(19)8-9(13(20)21)10(8)15(12,18)14(22)23/h1-3,8-12,19H,4,18H2,(H,20,21)(H,22,23)/t8-,9-,10-,11-,12+,15+/m0/s1
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n/an/an/an/a>2.50E+4n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...

Bioorg Med Chem Lett 26: 5663-5668 (2016)


Article DOI: 10.1016/j.bmcl.2016.10.067
BindingDB Entry DOI: 10.7270/Q2JS9SDT
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50121643
PNG
(CHEMBL3616847)
Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@H]2Sc1nnc[nH]1)C(O)=O |r|
Show InChI InChI=1S/C10H12N4O4S/c11-10(8(17)18)1-3(19-9-12-2-13-14-9)4-5(6(4)10)7(15)16/h2-6H,1,11H2,(H,15,16)(H,17,18)(H,12,13,14)/t3-,4+,5+,6+,10+/m1/s1
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n/an/an/an/a>2.50E+4n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant mGlu7 receptor expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by FLIPR assay

J Med Chem 58: 7526-48 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01124
BindingDB Entry DOI: 10.7270/Q29S1ST0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50244219
PNG
(CHEMBL4081453)
Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)c1cccc(OC)c1)C(O)=O |r|
Show InChI InChI=1S/C16H18N2O6/c1-24-8-4-2-3-7(5-8)13(19)18-9-6-16(17,15(22)23)12-10(9)11(12)14(20)21/h2-5,9-12H,6,17H2,1H3,(H,18,19)(H,20,21)(H,22,23)/t9-,10-,11-,12-,16-/m0/s1
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n/an/an/an/a>2.50E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing rat EAAT1/Galpha15 assessed as induction of increa...

J Med Chem 61: 2303-2328 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01481
BindingDB Entry DOI: 10.7270/Q2W95CM9
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50143059
PNG
(CHEMBL3758746)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O
Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20)
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n/an/an/an/a>3.00E+4n/an/an/an/a


TBA

Assay Description
Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127724
BindingDB Entry DOI: 10.7270/Q2WS8XWG
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50388941
PNG
(CHEMBL2063423)
Show SMILES O=NC1[C@@H]2C[C@@]2(Oc2ccccc12)C(=O)Nc1ccccn1 |r|
Show InChI InChI=1S/C16H13N3O3/c20-15(18-13-7-3-4-8-17-13)16-9-11(16)14(19-21)10-5-1-2-6-12(10)22-16/h1-8,11,14H,9H2,(H,17,18,20)/t11-,14?,16-/m0/s1
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n/an/an/an/a>3.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation activity at mGlu7 receptor

J Med Chem 55: 1445-64 (2012)


Article DOI: 10.1021/jm201139r
BindingDB Entry DOI: 10.7270/Q25D8SWH
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255435
PNG
(CHEMBL4101970)
Show SMILES N[C@@H](CCP(O)(=O)[C@H](O)c1cc(F)c(O)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H14FN2O8P/c12-6-3-5(4-8(9(6)15)14(19)20)11(18)23(21,22)2-1-7(13)10(16)17/h3-4,7,11,15,18H,1-2,13H2,(H,16,17)(H,21,22)/t7-,11-/m0/s1
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n/an/an/an/a 3.90E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50004881
PNG
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O
Show InChI InChI=1S/C8H10NO5P/c9-7(8(10)11)5-1-3-6(4-2-5)15(12,13)14/h1-4,7H,9H2,(H,10,11)(H2,12,13,14)
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n/an/an/an/a 4.80E+4n/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a

Bioorg Med Chem Lett 10: 1241-4 (2000)


BindingDB Entry DOI: 10.7270/Q26972SC
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50004881
PNG
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O
Show InChI InChI=1S/C8H10NO5P/c9-7(8(10)11)5-1-3-6(4-2-5)15(12,13)14/h1-4,7H,9H2,(H,10,11)(H2,12,13,14)
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n/an/an/an/a 4.80E+4n/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7b

Bioorg Med Chem Lett 10: 1241-4 (2000)


BindingDB Entry DOI: 10.7270/Q26972SC
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255407
PNG
(CHEMBL4077705)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1cc(F)c(O)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H14FN2O8P/c12-6-3-5(4-8(9(6)15)14(19)20)11(18)23(21,22)2-1-7(13)10(16)17/h3-4,7,11,15,18H,1-2,13H2,(H,16,17)(H,21,22)/t7-,11?/m0/s1
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n/an/an/an/a 5.12E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50446782
PNG
(CHEMBL3114672)
Show SMILES COc1cc(cc(c1O)[N+]([O-])=O)C(=O)P(O)(O)CC[C@H](N)C(O)=O |r|
Show InChI InChI=1S/C12H17N2O9P/c1-23-9-5-6(4-8(10(9)15)14(19)20)12(18)24(21,22)3-2-7(13)11(16)17/h4-5,7,15,21-22,24H,2-3,13H2,1H3,(H,16,17)/t7-/m0/s1
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n/an/an/an/a 5.30E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255414
PNG
(CHEMBL4096644)
Show SMILES N[C@@H](CCP(O)(=O)[C@@H](O)c1cc(F)c(O)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H14FN2O8P/c12-6-3-5(4-8(9(6)15)14(19)20)11(18)23(21,22)2-1-7(13)10(16)17/h3-4,7,11,15,18H,1-2,13H2,(H,16,17)(H,21,22)/t7-,11+/m0/s1
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n/an/an/an/a 5.38E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255340
PNG
(CHEMBL4072316)
Show SMILES N[C@@H](CCP(O)(=O)[C@H](O)c1ccc(O)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H15N2O8P/c12-7(10(15)16)3-4-22(20,21)11(17)6-1-2-9(14)8(5-6)13(18)19/h1-2,5,7,11,14,17H,3-4,12H2,(H,15,16)(H,20,21)/t7-,11-/m0/s1
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n/an/an/an/a 6.20E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255347
PNG
(CHEMBL4081842)
Show SMILES COc1cc(cc(c1O)[N+]([O-])=O)[C@@H](O)P(O)(=O)CC[C@H](N)C(O)=O |r|
Show InChI InChI=1S/C12H17N2O9P/c1-23-9-5-6(4-8(10(9)15)14(19)20)12(18)24(21,22)3-2-7(13)11(16)17/h4-5,7,12,15,18H,2-3,13H2,1H3,(H,16,17)(H,21,22)/t7-,12-/m0/s1
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n/an/an/an/a 6.30E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255339
PNG
(CHEMBL4060360)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(O)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H15N2O8P/c12-7(10(15)16)3-4-22(20,21)11(17)6-1-2-9(14)8(5-6)13(18)19/h1-2,5,7,11,14,17H,3-4,12H2,(H,15,16)(H,20,21)/t7-,11?/m0/s1
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n/an/an/an/a 6.90E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50314793
PNG
((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Show SMILES N[C@@H](CCP(O)(=O)CCC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C7H14NO6P/c8-5(7(11)12)1-3-15(13,14)4-2-6(9)10/h5H,1-4,8H2,(H,9,10)(H,11,12)(H,13,14)/t5-/m0/s1
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n/an/an/an/a 8.90E+4n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50056272
PNG
((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Show SMILES N[C@]1(CC[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C8H11NO4/c9-8(7(12)13)2-1-3-4(5(3)8)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7

J Med Chem 42: 1027-40 (1999)


Article DOI: 10.1021/jm980616n
BindingDB Entry DOI: 10.7270/Q2WM1CKF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50074749
PNG
((1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1.0]hexane-4...)
Show SMILES N[C@]1(CO[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H9NO5/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7

J Med Chem 42: 1027-40 (1999)


Article DOI: 10.1021/jm980616n
BindingDB Entry DOI: 10.7270/Q2WM1CKF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50074750
PNG
((1R,4S,5S,6S)-4-amino-2-thia-bicyclo[3.1.0]hexane-...)
Show SMILES N[C@]1(CS[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H9NO4S/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7

J Med Chem 42: 1027-40 (1999)


Article DOI: 10.1021/jm980616n
BindingDB Entry DOI: 10.7270/Q2WM1CKF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255397
PNG
(CHEMBL4090179)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(s1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C9H13N2O7PS/c10-5(8(12)13)3-4-19(17,18)9(14)6-1-2-7(20-6)11(15)16/h1-2,5,9,14H,3-4,10H2,(H,12,13)(H,17,18)/t5-,9?/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255342
PNG
(CHEMBL4063720)
Show SMILES COc1ccc(cc1[N+]([O-])=O)[C@@H](O)P(O)(=O)CC[C@H](N)C(O)=O |r|
Show InChI InChI=1S/C12H17N2O8P/c1-22-10-3-2-7(6-9(10)14(18)19)12(17)23(20,21)5-4-8(13)11(15)16/h2-3,6,8,12,17H,4-5,13H2,1H3,(H,15,16)(H,20,21)/t8-,12-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255337
PNG
(CHEMBL4063142)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(c(c1)[N+]([O-])=O)C(F)(F)F)C(O)=O |r|
Show InChI InChI=1S/C12H14F3N2O7P/c13-12(14,15)7-2-1-6(5-9(7)17(21)22)11(20)25(23,24)4-3-8(16)10(18)19/h1-2,5,8,11,20H,3-4,16H2,(H,18,19)(H,23,24)/t8-,11?/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255336
PNG
(CHEMBL4064187)
Show SMILES N[C@@H](CCP(O)(=O)Cc1cccc(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C11H15N2O6P/c12-10(11(14)15)4-5-20(18,19)7-8-2-1-3-9(6-8)13(16)17/h1-3,6,10H,4-5,7,12H2,(H,14,15)(H,18,19)/t10-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7


(Homo sapiens (Human))		BDBM50255333
PNG
(CHEMBL4082270)
Show SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(N2CCOCC2)c(c1)[N+]([O-])=O)C(O)=O |r|
Show InChI InChI=1S/C15H22N3O8P/c16-11(14(19)20)3-8-27(24,25)15(21)10-1-2-12(13(9-10)18(22)23)17-4-6-26-7-5-17/h1-2,9,11,15,21H,3-8,16H2,(H,19,20)(H,24,25)/t11-,15?/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair
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