BindingDB PrimarySearch

Found 919 hits of ec50 data for polymerid = 49000802,50002474,50002649
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neurotensin receptor type 1 (Rattus norvegicus)	BDBM50240845 ((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0100	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at rat NTS1 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay				J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Rattus norvegicus)	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at rat NTS1 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay				J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0420	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ l...				Bioorg Med Chem Lett 24: 3974-8 (2014) Article DOI: 10.1016/j.bmcl.2014.06.033 BindingDB Entry DOI: 10.7270/Q2ZP47RG
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0692	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 expressed in CHO cells assessed as increase in intracellular calcium by Fluo-4 dye based fluorescenc...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.230	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at NTR1 (unknown origin) expressed in CHOK1 cells by calcium mobilization assay				Bioorg Med Chem Lett 19: 1438-41 (2009) Article DOI: 10.1016/j.bmcl.2009.01.024 BindingDB Entry DOI: 10.7270/Q2S46RVQ
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553767 (CHEMBL4789659) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.240	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553768 (CHEMBL4744531) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50124135 (CHEMBL3622803) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing hNTS1-GFP10/RlucII-beta-arrestin 2 assessed as beta-arrestin2 recruitm...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50509513 (CHEMBL4537266) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.372	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 expressed in CHO cells assessed as increase in intracellular calcium by Fluo-4 dye based fluorescenc...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at Galpha13-Rluc2/Gbeta1/GFP10-Ggamma1 fused human NTS1 expressed in CHO-K1 cell membranes assessed as Galpha13 activation after 5 m...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50509511 (CHEMBL4457798) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.417	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 expressed in CHO cells assessed as increase in intracellular calcium by Fluo-4 dye based fluorescenc...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at GFP10/beta-arrestin1-Rluc2 fused human NTS1 expressed in CHO-K1 cell membranes assessed as beta-arrestin1 recruitment after 20 mi...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at GFP10/beta-arrestin2-Rluc2 fused human NTS1 expressed in CHO-K1 cell membranes assessed as beta-arrestin2 recruitment after 20 mi...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at Galphaq-Rluc2/Gbeta1/GFP10-Ggamma1 fused human NTS1 expressed in CHO-K1 cell membranes assessed as Galphaq activation after 5 min...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50257186 ((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-azido...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.780	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50257185 ((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-5-guanidino-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.853	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553771 (CHEMBL4776986) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.860	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50240845 ((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50509510 (CHEMBL4564746) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 in HT-29 cells assessed as intracellular calcium mobilization by Fura-2 dye based spectrofluorimetry...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM297513 (2-({2-(1-Fluoro-cyclopropyl)-4-[4- (2-methoxy-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of human GFP-fused PK-tagged Gq-coupled NTR1 expressed in CHOK1 cells assessed as effect on NT (8 to 13) peptide-media...				J Med Chem 62: 8357-8363 (2019) Article DOI: 10.1021/acs.jmedchem.9b00340 BindingDB Entry DOI: 10.7270/Q2HQ438V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 in HT-29 cells assessed as intracellular calcium mobilization by Fura-2 dye based spectrofluorimetry...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553769 (CHEMBL4798887) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Rattus norvegicus)	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 in Sprague-Dawley rat ileum assessed as inhibition of carbachol-induced contraction				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Rattus norvegicus)	BDBM50124132 (CHEMBL3622802) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 in Sprague-Dawley rat ileum assessed as inhibition of carbachol-induced contraction				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing Galphaq-RlucII(121)/Gbeta1/GFP10-Ggamma1 assessed as Galpha-q stimulat...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50276349 (CHEMBL450740 \| Polyamine-NT) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Agonist activity at human recombinant NTS1 receptor expressed in HEK293 cells assessed as stimulation of Ca2+ mobilization				J Med Chem 52: 1514-7 (2009) Article DOI: 10.1021/jm801481y BindingDB Entry DOI: 10.7270/Q2M908JS
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50124132 (CHEMBL3622802) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing Galphaq-RlucII(121)/Gbeta1/GFP10-Ggamma1 assessed as Galpha-q stimulat...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50124132 (CHEMBL3622802) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing hNTS1-GFP10/RlucII-beta-arrestin 2 assessed as beta-arrestin2 recruitm...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50159155 (CHEMBL3786852) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553777 (CHEMBL4597094) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50159155 (CHEMBL3786852) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553772 (CHEMBL4749016) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50257188 ((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-5-guanidino-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.85	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50240844 ((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-aceta...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.89	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing hNTS1-GFP10/RlucII-beta-arrestin 2 assessed as beta-arrestin2 recruitm...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.98	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in human HT-29 cells assessed as increase in intracellular calcium concentration by FLIPR assay				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at human NTR1 assessed as increase in intracellular calcium concentration				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50159156 (CHEMBL3786291) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50159156 (CHEMBL3786291) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...				J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (MOUSE)	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Agonist activity at NTR1 in mouse N1E-115 cells assessed as increase in intracellular calcium concentration				J Med Chem 52: 1803-13 (2009) Article DOI: 10.1021/jm801072v BindingDB Entry DOI: 10.7270/Q2VD6Z9D
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50458820 (CHEMBL4216311) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at Galphaq-Rluc2/Gbeta1/GFP10-Ggamma1 fused human NTS1 expressed in CHO-K1 cell membranes assessed as Galphaq activation after 5 min...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50458820 (CHEMBL4216311) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at GFP10/beta-arrestin2-Rluc2 fused human NTS1 expressed in CHO-K1 cell membranes assessed as beta-arrestin2 recruitment after 20 mi...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50553770 (CHEMBL4758754) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P
TBA					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50458820 (CHEMBL4216311) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Agonist activity at GFP10/beta-arrestin1-Rluc2 fused human NTS1 expressed in CHO-K1 cell membranes assessed as beta-arrestin1 recruitment after 20 mi...				J Med Chem 61: 7103-7115 (2018) Article DOI: 10.1021/acs.jmedchem.8b00175 BindingDB Entry DOI: 10.7270/Q2D50QMT
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50124141 (CHEMBL3622805) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Universit£ Montpellier Curated by ChEMBL					Assay Description Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing hNTS1-GFP10/RlucII-beta-arrestin 2 assessed as beta-arrestin2 recruitm...				J Med Chem 58: 7785-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b00841 BindingDB Entry DOI: 10.7270/Q2MW2JZ3
Universit£ Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50509511 (CHEMBL4457798) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at human neurotensin receptor 1 in HT-29 cells assessed as intracellular calcium mobilization by Fura-2 dye based spectrofluorimetry...				ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 BindingDB Entry DOI: 10.7270/Q2SF30GN
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 919 total ) | Next | Last >>