Compile Data Set for Download or QSAR

Found 108 hits of ec50 data for polymerid = 49000929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127794 (CHEMBL48848 | Furan-2-carboxylic acid [2-(2,2,2-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccco1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H11F6NO3/c19-17(20,21)16(27,18(22,23)24)12-8-7-10-4-1-2-5-11(10)14(12)25-15(26)13-6-3-9-28-13/h1-9,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127798 (CHEMBL50374 | Thiophene-2-carboxylic acid [2-(2,2,...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccs1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H11F6NO2S/c19-17(20,21)16(27,18(22,23)24)12-8-7-10-4-1-2-5-11(10)14(12)25-15(26)13-6-3-9-28-13/h1-9,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127806 (3-Cyano-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(c1)C#N)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F6N2O2/c22-20(23,24)19(31,21(25,26)27)16-9-8-13-5-1-2-7-15(13)17(16)29-18(30)14-6-3-4-12(10-14)11-28/h1-10,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127801 (CHEMBL50760 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES CCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H13F6NO2/c1-2-12(24)23-13-10-6-4-3-5-9(10)7-8-11(13)14(25,15(17,18)19)16(20,21)22/h3-8,25H,2H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127768 (CHEMBL299167 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-t...) Show SMILES CC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H11F6NO2/c1-8(23)22-12-10-5-3-2-4-9(10)6-7-11(12)13(24,14(16,17)18)15(19,20)21/h2-7,24H,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127788 (3-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES Cc1cccc(c1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO2/c1-12-5-4-7-14(11-12)18(29)28-17-15-8-3-2-6-13(15)9-10-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127793 (CHEMBL48797 | Oxazole-5-carboxylic acid [2-(2,2,2-...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cnco1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F6N2O3/c18-16(19,20)15(27,17(21,22)23)11-6-5-9-3-1-2-4-10(9)13(11)25-14(26)12-7-24-8-28-12/h1-8,27H,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127799 (CHEMBL51071 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H13F6NO2/c21-19(22,23)18(29,20(24,25)26)15-11-10-12-6-4-5-9-14(12)16(15)27-17(28)13-7-2-1-3-8-13/h1-11,29H,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127792 (3-Fluoro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(F)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F7NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127762 (CHEMBL47170 | Cyclobutanecarboxylic acid [2-(2,2,2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c19-17(20,21)16(27,18(22,23)24)13-9-8-10-4-1-2-7-12(10)14(13)25-15(26)11-5-3-6-11/h1-2,4,7-9,11,27H,3,5-6H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127764 (3-Methyl-but-2-enoic acid [2-(2,2,2-trifluoro-1-hy...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1c(ccc2ccccc12)C([#8])(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c1-10(2)9-14(26)25-15-12-6-4-3-5-11(12)7-8-13(15)16(27,17(19,20)21)18(22,23)24/h3-9,27H,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127785 (4-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12BrF6NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127771 (4-Methyl-pentanoic acid [2-(2,2,2-trifluoro-1-hydr...) Show SMILES CC(C)CCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H19F6NO2/c1-11(2)7-10-15(27)26-16-13-6-4-3-5-12(13)8-9-14(16)17(28,18(20,21)22)19(23,24)25/h3-6,8-9,11,28H,7,10H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127783 (CHEMBL49076 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccnc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H12F6N2O2/c20-18(21,22)17(29,19(23,24)25)14-8-7-11-4-1-2-6-13(11)15(14)27-16(28)12-5-3-9-26-10-12/h1-10,29H,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127766 (4-Fluoro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F7NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127777 (But-2-enoic acid [2-(2,2,2-trifluoro-1-hydroxy-1-t...) Show SMILES C\C=C\C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H13F6NO2/c1-2-5-13(25)24-14-11-7-4-3-6-10(11)8-9-12(14)15(26,16(18,19)20)17(21,22)23/h2-9,26H,1H3,(H,24,25)/b5-2+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127763 (4-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES Cc1ccc(cc1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO2/c1-12-6-8-14(9-7-12)18(29)28-17-15-5-3-2-4-13(15)10-11-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127797 (3-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(Br)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12BrF6NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127807 (2-Cyclopentyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)CC1CCCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H19F6NO2/c21-19(22,23)18(29,20(24,25)26)15-10-9-13-7-3-4-8-14(13)17(15)27-16(28)11-12-5-1-2-6-12/h3-4,7-10,12,29H,1-2,5-6,11H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127775 (CHEMBL298970 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-t...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(c1)C(F)(F)F)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F9NO2/c22-19(23,24)13-6-3-5-12(10-13)17(32)31-16-14-7-2-1-4-11(14)8-9-15(16)18(33,20(25,26)27)21(28,29)30/h1-10,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127802 (3-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12ClF6NO2/c21-13-6-3-5-12(10-13)17(29)28-16-14-7-2-1-4-11(14)8-9-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127774 (3-Nitro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cccc(c1)[N+]([O-])=O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F6N2O4/c21-19(22,23)18(30,20(24,25)26)15-9-8-11-4-1-2-7-14(11)16(15)27-17(29)12-5-3-6-13(10-12)28(31)32/h1-10,30H,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127786 (CHEMBL49797 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES CCCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO2/c1-2-5-13(25)24-14-11-7-4-3-6-10(11)8-9-12(14)15(26,16(18,19)20)17(21,22)23/h3-4,6-9,26H,2,5H2,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127781 (CHEMBL49701 | N-[5-Hydroxy-2-(2,2,2-trifluoro-1-hy...) Show SMILES CC(=O)Nc1c(ccc2c(O)cccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H11F6NO3/c1-7(23)22-12-9-3-2-4-11(24)8(9)5-6-10(12)13(25,14(16,17)18)15(19,20)21/h2-6,24-25H,1H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	137	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127769 (4-Iodo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoro...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(I)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F6INO2/c21-19(22,23)18(30,20(24,25)26)15-10-7-11-3-1-2-4-14(11)16(15)28-17(29)12-5-8-13(27)9-6-12/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	154	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127784 (CHEMBL48801 | N-[2-(2,2,2-Trifluoro-1-hydroxy-1-tr...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(cc1)C(F)(F)F)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H12F9NO2/c22-19(23,24)13-8-5-12(6-9-13)17(32)31-16-14-4-2-1-3-11(14)7-10-15(16)18(33,20(25,26)27)21(28,29)30/h1-10,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127811 (3-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES COc1cccc(c1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO3/c1-31-14-7-4-6-13(11-14)18(29)28-17-15-8-3-2-5-12(15)9-10-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	185	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127773 (3,4-Dichloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tri...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Cl)c(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11Cl2F6NO2/c21-14-8-6-11(9-15(14)22)17(30)29-16-12-4-2-1-3-10(12)5-7-13(16)18(31,19(23,24)25)20(26,27)28/h1-9,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	194	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127787 (2-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES COCC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H13F6NO3/c1-26-8-12(24)23-13-10-5-3-2-4-9(10)6-7-11(13)14(25,15(17,18)19)16(20,21)22/h2-7,25H,8H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	213	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127776 (1-(4-Chloro-phenyl)-3-[2-(2,2,2-trifluoro-1-hydrox...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)Nc1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H13ClF6N2O2/c21-12-6-8-13(9-7-12)28-17(30)29-16-14-4-2-1-3-11(14)5-10-15(16)18(31,19(22,23)24)20(25,26)27/h1-10,31H,(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	276	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127778 (3,5-Dichloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tri...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cc(Cl)cc(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11Cl2F6NO2/c21-12-7-11(8-13(22)9-12)17(30)29-16-14-4-2-1-3-10(14)5-6-15(16)18(31,19(23,24)25)20(26,27)28/h1-9,31H,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	306	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127767 (CHEMBL301591 | Quinoxaline-2-carboxylic acid [2-(2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1cnc2ccccc2n1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H13F6N3O2/c23-21(24,25)20(33,22(26,27)28)14-10-9-12-5-1-2-6-13(12)18(14)31-19(32)17-11-29-15-7-3-4-8-16(15)30-17/h1-11,33H,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50207690 (CHEMBL239512) Show SMILES CC(Cl)(Cl)[C@H](N\C(Nc1cccnc1)=N\C#N)NC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15Cl3N6O/c1-17(19,20)15(25-14(27)11-4-6-12(18)7-5-11)26-16(23-10-21)24-13-3-2-8-22-9-13/h2-9,15H,1H3,(H,25,27)(H2,23,24,26)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	339	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127795 (4-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES COc1ccc(cc1)C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO3/c1-31-14-9-6-13(7-10-14)18(29)28-17-15-5-3-2-4-12(15)8-11-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86249 (ZD 6169 | ZD-6169) Show SMILES C[C@](O)(C(=O)Nc1ccc(cc1)C(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	437	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477271 (CHEMBL239514) Show SMILES CC(Cl)(Cl)C(N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14Cl4N6O/c1-17(20,21)15(26-14(28)10-2-4-11(18)5-3-10)27-16(24-9-22)25-12-6-7-13(19)23-8-12/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	457	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127789 (CHEMBL49191 | Cyclopentanecarboxylic acid [2-(2,2,...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CCCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H17F6NO2/c20-18(21,22)17(28,19(23,24)25)14-10-9-11-5-3-4-8-13(11)15(14)26-16(27)12-6-1-2-7-12/h3-5,8-10,12,28H,1-2,6-7H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	495	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477275 (CHEMBL391369) Show SMILES CC(Cl)(Cl)C(N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C17H14BrCl3N6O/c1-17(20,21)15(26-14(28)10-2-4-11(18)5-3-10)27-16(24-9-22)25-12-6-7-13(19)23-8-12/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	537	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127791 (4-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)c1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12ClF6NO2/c21-13-8-5-12(6-9-13)17(29)28-16-14-4-2-1-3-11(14)7-10-15(16)18(30,19(22,23)24)20(25,26)27/h1-10,30H,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477286 (CHEMBL393831) Show SMILES CC(Cl)(Cl)C(N\C(Nc1cncc(Br)c1)=N\C#N)NC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14BrCl3N6O/c1-17(20,21)15(26-14(28)10-2-4-12(19)5-3-10)27-16(24-9-22)25-13-6-11(18)7-23-8-13/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50127800 (CHEMBL296840 | Cyclopropanecarboxylic acid [2-(2,2...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)C1CC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H13F6NO2/c18-16(19,20)15(26,17(21,22)23)12-8-7-9-3-1-2-4-11(9)13(12)24-14(25)10-5-6-10/h1-4,7-8,10,26H,5-6H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	751	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477262 (CHEMBL238883) Show SMILES Cc1cncc(N\C(NC(NC(=O)c2ccc(Cl)cc2)C(C)(Cl)Cl)=N/C#N)c1 Show InChI InChI=1S/C18H17Cl3N6O/c1-11-7-14(9-23-8-11)25-17(24-10-22)27-16(18(2,20)21)26-15(28)12-3-5-13(19)6-4-12/h3-9,16H,1-2H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477295 (CHEMBL241199) Show SMILES CC(Cl)(Cl)C(N\C(Nc1cncc(Br)c1)=N\C#N)NC(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C17H14BrCl3N6O/c1-17(20,21)15(26-14(28)10-3-2-4-12(19)5-10)27-16(24-9-22)25-13-6-11(18)7-23-8-13/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	776	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477269 (CHEMBL239119) Show SMILES CC(Cl)(Cl)C(N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H13Cl5N6O/c1-17(21,22)15(27-14(29)9-4-10(18)6-11(19)5-9)28-16(25-8-23)26-12-2-3-13(20)24-7-12/h2-7,15H,1H3,(H,27,29)(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477288 (CHEMBL239121) Show SMILES CC(Cl)(Cl)C(N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1ccc(I)cc1 Show InChI InChI=1S/C17H14Cl3IN6O/c1-17(19,20)15(26-14(28)10-2-4-11(21)5-3-10)27-16(24-9-22)25-12-6-7-13(18)23-8-12/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	891	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477293 (CHEMBL239128) Show SMILES Cc1ccc(cc1)C(=O)NC(N\C(Nc1ccc(Cl)nc1)=N\C#N)C(C)(Cl)Cl Show InChI InChI=1S/C18H17Cl3N6O/c1-11-3-5-12(6-4-11)15(28)26-16(18(2,20)21)27-17(24-10-22)25-13-7-8-14(19)23-9-13/h3-9,16H,1-2H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	912	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477299 (CHEMBL393424) Show SMILES CC(Cl)(Cl)C(N\C(Nc1cncc(Br)c1)=N\C#N)NC(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H14BrCl2FN6O/c1-17(19,20)15(26-14(28)10-2-4-12(21)5-3-10)27-16(24-9-22)25-13-6-11(18)7-23-8-13/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	955	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477280 (CHEMBL274449) Show SMILES CC(Cl)(Cl)[C@H](N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14Cl4N6O/c1-17(20,21)15(26-14(28)10-2-4-11(18)5-3-10)27-16(24-9-22)25-12-6-7-13(19)23-8-12/h2-8,15H,1H3,(H,26,28)(H2,24,25,27)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477297 (CHEMBL410755) Show SMILES CC(Cl)(Cl)C(N\C(Nc1ccc(Cl)nc1)=N\C#N)NC(=O)c1cc(F)cc(F)c1 Show InChI InChI=1S/C17H13Cl3F2N6O/c1-17(19,20)15(27-14(29)9-4-10(21)6-11(22)5-9)28-16(25-8-23)26-12-2-3-13(18)24-7-12/h2-7,15H,1H3,(H,27,29)(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50477305 (CHEMBL241200) Show SMILES CC(Cl)(Cl)C(N\C(Nc1cncc(Br)c1)=N\C#N)NC(=O)c1cc(F)cc(F)c1 Show InChI InChI=1S/C17H13BrCl2F2N6O/c1-17(19,20)15(27-14(29)9-2-11(21)5-12(22)3-9)28-16(25-8-23)26-13-4-10(18)6-24-7-13/h2-7,15H,1H3,(H,27,29)(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay				J Med Chem 50: 6265-73 (2007) Article DOI: 10.1021/jm7010194 BindingDB Entry DOI: 10.7270/Q2VM4G2S
					More data for this Ligand-Target Pair

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