Found 21 hits of ec50 data for polymerid = 49001077,49001080 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vasopressin V1a receptor
(RAT) | BDBM50350866
(CHEMBL1819441)Show SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O |r| Show InChI InChI=1S/C46H65N15O11S2/c47-27-23-73-74-24-33(45(72)61-18-8-14-34(61)44(71)56-28(13-7-17-53-46(51)52)39(66)54-22-37(50)64)60-43(70)32(21-36(49)63)59-40(67)29(15-16-35(48)62)55-41(68)31(20-26-11-5-2-6-12-26)58-42(69)30(57-38(27)65)19-25-9-3-1-4-10-25/h1-6,9-12,27-34H,7-8,13-24,47H2,(H2,48,62)(H2,49,63)(H2,50,64)(H,54,66)(H,55,68)(H,56,71)(H,57,65)(H,58,69)(H,59,67)(H,60,70)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1 | UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350852
(CHEMBL1817706)Show SMILES CCCNCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H71N13O11S2/c1-4-17-50-18-9-13-28(39(63)51-22-36(49)61)52-43(67)33-14-10-19-58(33)45(69)32-24-71-70-23-27(46)38(62)54-30(20-26-11-7-6-8-12-26)42(66)57-37(25(3)5-2)44(68)53-29(15-16-34(47)59)40(64)55-31(21-35(48)60)41(65)56-32/h6-8,11-12,25,27-33,37,50H,4-5,9-10,13-24,46H2,1-3H3,(H2,47,59)(H2,48,60)(H2,49,61)(H,51,63)(H,52,67)(H,53,68)(H,54,62)(H,55,64)(H,56,65)(H,57,66)/t25-,27-,28-,29-,30-,31-,32-,33-,37-/m0/s1 | UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.105 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350876
(CHEMBL1819542)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C42H65N13O11S2/c1-3-22(2)34-41(65)50-26(13-14-31(45)56)37(61)52-28(18-32(46)57)38(62)53-29(21-68-67-20-24(44)35(59)51-27(39(63)54-34)17-23-9-5-4-6-10-23)42(66)55-16-8-12-30(55)40(64)49-25(11-7-15-43)36(60)48-19-33(47)58/h4-6,9-10,22,24-30,34H,3,7-8,11-21,43-44H2,1-2H3,(H2,45,56)(H2,46,57)(H2,47,58)(H,48,60)(H,49,64)(H,50,65)(H,51,59)(H,52,61)(H,53,62)(H,54,63)/t22-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1 | UniProtKB/SwissProt
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| n/a | n/a | n/a | n/a | 0.123 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350869
(CHEMBL1817704)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H71N13O11S2/c1-5-25(4)37-44(68)53-29(15-16-34(47)59)40(64)55-31(20-35(48)60)41(65)56-32(23-71-70-22-27(46)38(62)54-30(42(66)57-37)19-26-11-7-6-8-12-26)45(69)58-18-10-14-33(58)43(67)52-28(13-9-17-50-24(2)3)39(63)51-21-36(49)61/h6-8,11-12,24-25,27-33,37,50H,5,9-10,13-23,46H2,1-4H3,(H2,47,59)(H2,48,60)(H2,49,61)(H,51,63)(H,52,67)(H,53,68)(H,54,62)(H,55,64)(H,56,65)(H,57,66)/t25-,27-,28-,29-,30-,31-,32-,33-,37-/m0/s1 | UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.126 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350853
(CHEMBL1817707)Show SMILES CCNCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C44H69N13O11S2/c1-4-24(3)36-43(67)52-28(15-16-33(46)58)39(63)54-30(20-34(47)59)40(64)55-31(23-70-69-22-26(45)37(61)53-29(41(65)56-36)19-25-11-7-6-8-12-25)44(68)57-18-10-14-32(57)42(66)51-27(13-9-17-49-5-2)38(62)50-21-35(48)60/h6-8,11-12,24,26-32,36,49H,4-5,9-10,13-23,45H2,1-3H3,(H2,46,58)(H2,47,59)(H2,48,60)(H,50,62)(H,51,66)(H,52,67)(H,53,61)(H,54,63)(H,55,64)(H,56,65)/t24-,26-,27-,28-,29-,30-,31-,32-,36-/m0/s1 | UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.162 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350851
(CHEMBL1817705)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H67N13O11S2/c1-4-23(2)35-42(66)51-27(14-15-32(45)57)38(62)53-29(19-33(46)58)39(63)54-30(22-69-68-21-25(44)36(60)52-28(40(64)55-35)18-24-10-6-5-7-11-24)43(67)56-17-9-13-31(56)41(65)50-26(12-8-16-48-3)37(61)49-20-34(47)59/h5-7,10-11,23,25-31,35,48H,4,8-9,12-22,44H2,1-3H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,49,61)(H,50,65)(H,51,66)(H,52,60)(H,53,62)(H,54,63)(H,55,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350872
(CHEMBL1817761)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2cccs2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H69N13O11S3/c1-5-23(4)35-42(66)51-27(12-13-32(45)57)38(62)53-29(18-33(46)58)39(63)54-30(21-70-69-20-25(44)36(60)52-28(40(64)55-35)17-24-9-8-16-68-24)43(67)56-15-7-11-31(56)41(65)50-26(10-6-14-48-22(2)3)37(61)49-19-34(47)59/h8-9,16,22-23,25-31,35,48H,5-7,10-15,17-21,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,49,61)(H,50,65)(H,51,66)(H,52,60)(H,53,62)(H,54,63)(H,55,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350849
(CHEMBL1817702)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H67N13O11S2/c1-3-23(2)35-42(66)51-27(12-7-15-32(46)57)38(62)53-29(19-33(47)58)39(63)54-30(22-69-68-21-25(45)36(60)52-28(40(64)55-35)18-24-10-5-4-6-11-24)43(67)56-17-9-14-31(56)41(65)50-26(13-8-16-44)37(61)49-20-34(48)59/h4-6,10-11,23,25-31,35H,3,7-9,12-22,44-45H2,1-2H3,(H2,46,57)(H2,47,58)(H2,48,59)(H,49,61)(H,50,65)(H,51,66)(H,52,60)(H,53,62)(H,54,63)(H,55,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.340 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350865
(CHEMBL1819440)Show SMILES NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H63N13O12S2/c46-16-4-8-28(39(64)51-21-37(50)62)53-44(69)34-9-5-17-58(34)45(70)33-23-72-71-22-27(47)38(63)54-30(19-25-10-12-26(59)13-11-25)42(67)55-31(18-24-6-2-1-3-7-24)41(66)52-29(14-15-35(48)60)40(65)56-32(20-36(49)61)43(68)57-33/h1-3,6-7,10-13,27-34,59H,4-5,8-9,14-23,46-47H2,(H2,48,60)(H2,49,61)(H2,50,62)(H,51,64)(H,52,66)(H,53,69)(H,54,63)(H,55,67)(H,56,65)(H,57,68)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1 | UniProtKB/SwissProt
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| Article
PubMed
| n/a | n/a | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350864
(CHEMBL1819439)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](O)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCNC(=O)C(N)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C45H69N13O13S2/c1-4-23(3)36-44(70)53-26(13-14-33(47)60)39(65)54-29(19-34(48)61)40(66)56-30(21-72-73-22-32(59)43(69)55-28(41(67)57-36)18-24-10-7-6-8-11-24)45(71)58-17-9-12-31(58)42(68)52-27(38(64)51-20-35(49)62)15-16-50-37(63)25(46)5-2/h6-8,10-11,23,25-32,36,59H,4-5,9,12-22,46H2,1-3H3,(H2,47,60)(H2,48,61)(H2,49,62)(H,50,63)(H,51,64)(H,52,68)(H,53,70)(H,54,65)(H,55,69)(H,56,66)(H,57,67)/t23-,25?,26-,27-,28-,29-,30-,31-,32-,36-/m0/s1 | UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350870
(CHEMBL1817709)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C46H73N13O11S2/c1-5-26(4)38-45(69)54-30(14-9-17-35(48)60)41(65)56-32(21-36(49)61)42(66)57-33(24-72-71-23-28(47)39(63)55-31(43(67)58-38)20-27-12-7-6-8-13-27)46(70)59-19-11-16-34(59)44(68)53-29(15-10-18-51-25(2)3)40(64)52-22-37(50)62/h6-8,12-13,25-26,28-34,38,51H,5,9-11,14-24,47H2,1-4H3,(H2,48,60)(H2,49,61)(H2,50,62)(H,52,64)(H,53,68)(H,54,69)(H,55,63)(H,56,65)(H,57,66)(H,58,67)/t26-,28-,29-,30-,31-,32-,33-,34-,38-/m0/s1 | UniProtKB/SwissProt
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| n/a | n/a | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350871
(CHEMBL1817756)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccco2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H69N13O12S2/c1-5-23(4)35-42(66)51-27(12-13-32(45)57)38(62)53-29(18-33(46)58)39(63)54-30(21-70-69-20-25(44)36(60)52-28(40(64)55-35)17-24-9-8-16-68-24)43(67)56-15-7-11-31(56)41(65)50-26(10-6-14-48-22(2)3)37(61)49-19-34(47)59/h8-9,16,22-23,25-31,35,48H,5-7,10-15,17-21,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,49,61)(H,50,65)(H,51,66)(H,52,60)(H,53,62)(H,54,63)(H,55,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
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| Article
PubMed
| n/a | n/a | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350842
(CHEMBL1817695)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)N(C)C)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H67N13O11S2/c1-5-23(2)35-42(66)52-29(19-34(59)55(3)4)39(63)51-28(18-32(46)57)38(62)53-30(22-69-68-21-25(45)36(60)50-27(40(64)54-35)17-24-11-7-6-8-12-24)43(67)56-16-10-14-31(56)41(65)49-26(13-9-15-44)37(61)48-20-33(47)58/h6-8,11-12,23,25-31,35H,5,9-10,13-22,44-45H2,1-4H3,(H2,46,57)(H2,47,58)(H,48,61)(H,49,65)(H,50,60)(H,51,63)(H,52,66)(H,53,62)(H,54,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350856
(CHEMBL1817749)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C40H61N13O11S2/c1-3-20(2)32-39(63)50-26(16-30(44)55)35(59)49-25(15-29(43)54)36(60)51-27(19-66-65-18-22(42)33(57)48-24(37(61)52-32)14-21-8-5-4-6-9-21)40(64)53-13-7-10-28(53)38(62)47-23(11-12-41)34(58)46-17-31(45)56/h4-6,8-9,20,22-28,32H,3,7,10-19,41-42H2,1-2H3,(H2,43,54)(H2,44,55)(H2,45,56)(H,46,58)(H,47,62)(H,48,57)(H,49,59)(H,50,63)(H,51,60)(H,52,61)/t20-,22-,23-,24-,25-,26-,27-,28-,32-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350868
(CHEMBL1819555)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C41H69N13O11S2/c1-3-21(2)33-40(64)49-24(11-12-30(44)55)36(60)51-27(17-31(45)56)37(61)52-28(20-67-66-19-23(43)34(58)50-26(38(62)53-33)16-22-8-5-4-6-9-22)41(65)54-15-7-10-29(54)39(63)48-25(13-14-42)35(59)47-18-32(46)57/h21-29,33H,3-20,42-43H2,1-2H3,(H2,44,55)(H2,45,56)(H2,46,57)(H,47,59)(H,48,63)(H,49,64)(H,50,58)(H,51,60)(H,52,61)(H,53,62)/t21-,23-,24-,25-,26-,27-,28-,29-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350845
(CHEMBL1817698)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)NCCCO)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C44H69N13O12S2/c1-3-24(2)36-43(68)54-30(20-35(61)49-15-9-17-58)40(65)53-29(19-33(47)59)39(64)55-31(23-71-70-22-26(46)37(62)52-28(41(66)56-36)18-25-10-5-4-6-11-25)44(69)57-16-8-13-32(57)42(67)51-27(12-7-14-45)38(63)50-21-34(48)60/h4-6,10-11,24,26-32,36,58H,3,7-9,12-23,45-46H2,1-2H3,(H2,47,59)(H2,48,60)(H,49,61)(H,50,63)(H,51,67)(H,52,62)(H,53,65)(H,54,68)(H,55,64)(H,56,66)/t24-,26-,27-,28-,29-,30-,31-,32-,36-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350867
(CHEMBL1819554)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CC2CCCC2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C40H67N13O11S2/c1-3-20(2)32-39(63)48-23(10-11-29(43)54)35(59)50-26(16-30(44)55)36(60)51-27(19-66-65-18-22(42)33(57)49-25(37(61)52-32)15-21-7-4-5-8-21)40(64)53-14-6-9-28(53)38(62)47-24(12-13-41)34(58)46-17-31(45)56/h20-28,32H,3-19,41-42H2,1-2H3,(H2,43,54)(H2,44,55)(H2,45,56)(H,46,58)(H,47,62)(H,48,63)(H,49,57)(H,50,59)(H,51,60)(H,52,61)/t20-,22-,23-,24-,25-,26-,27-,28-,32-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350858
(CHEMBL1817751)Show SMILES CCNC(=O)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCN)C(=O)NCC(N)=O)[C@@H](C)CC |r| Show InChI InChI=1S/C42H65N13O11S2/c1-4-22(3)34-41(65)52-28(18-33(58)47-5-2)38(62)51-27(17-31(45)56)37(61)53-29(21-68-67-20-24(44)35(59)50-26(39(63)54-34)16-23-10-7-6-8-11-23)42(66)55-15-9-12-30(55)40(64)49-25(13-14-43)36(60)48-19-32(46)57/h6-8,10-11,22,24-30,34H,4-5,9,12-21,43-44H2,1-3H3,(H2,45,56)(H2,46,57)(H,47,58)(H,48,60)(H,49,64)(H,50,59)(H,51,62)(H,52,65)(H,53,61)(H,54,63)/t22-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350861
(CHEMBL1817754)Show SMILES CCNCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C43H67N13O11S2/c1-4-23(3)35-42(66)53-29(19-33(46)58)38(62)52-28(18-32(45)57)39(63)54-30(22-69-68-21-25(44)36(60)51-27(40(64)55-35)17-24-11-7-6-8-12-24)43(67)56-16-10-14-31(56)41(65)50-26(13-9-15-48-5-2)37(61)49-20-34(47)59/h6-8,11-12,23,25-31,35,48H,4-5,9-10,13-22,44H2,1-3H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,49,61)(H,50,65)(H,51,60)(H,52,62)(H,53,66)(H,54,63)(H,55,64)/t23-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350839
(CHEMBL1817692)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C41H63N13O11S2/c1-3-21(2)33-40(64)51-27(17-31(45)56)36(60)50-26(16-30(44)55)37(61)52-28(20-67-66-19-23(43)34(58)49-25(38(62)53-33)15-22-9-5-4-6-10-22)41(65)54-14-8-12-29(54)39(63)48-24(11-7-13-42)35(59)47-18-32(46)57/h4-6,9-10,21,23-29,33H,3,7-8,11-20,42-43H2,1-2H3,(H2,44,55)(H2,45,56)(H2,46,57)(H,47,59)(H,48,63)(H,49,58)(H,50,60)(H,51,64)(H,52,61)(H,53,62)/t21-,23-,24-,25-,26-,27-,28-,29-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
Vasopressin V1a receptor
(RAT) | BDBM50350873
(CHEMBL1817770)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C44H75N13O11S2/c1-5-24(4)36-43(67)54-30(19-34(47)59)39(63)53-29(18-33(46)58)40(64)55-31(22-70-69-21-26(45)37(61)52-28(41(65)56-36)17-25-11-7-6-8-12-25)44(68)57-16-10-14-32(57)42(66)51-27(13-9-15-49-23(2)3)38(62)50-20-35(48)60/h23-32,36,49H,5-22,45H2,1-4H3,(H2,46,58)(H2,47,59)(H2,48,60)(H,50,62)(H,51,66)(H,52,61)(H,53,63)(H,54,67)(H,55,64)(H,56,65)/t24-,26-,27-,28-,29-,30-,31-,32-,36-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
Ferring Research Institute Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay |
J Med Chem 54: 4388-98 (2011)
Article DOI: 10.1021/jm200278m
BindingDB Entry DOI: 10.7270/Q2JW8F8J |
More data for this
Ligand-Target Pair | |
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