Compile Data Set for Download or QSAR

Found 56 hits of ec50 data for polymerid = 50000001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247680 ((-)-3-chlorophenyl (3S,4R)-6-cyano-3-hydroxy-2,2-d...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NC(=O)c2cccc(Cl)c2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-8-11(10-21)6-7-15(14)25-19)22-18(24)12-4-3-5-13(20)9-12/h3-9,16-17,23H,1-2H3,(H,22,24)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247678 ((+/-)-3-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2C(NC(=O)c2cccc(Cl)c2)C1O)C#N Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-8-11(10-21)6-7-15(14)25-19)22-18(24)12-4-3-5-13(20)9-12/h3-9,16-17,23H,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50062397 (3N-cyanoimino(tert-pentylamino)methyl-3-pyridinami...) Show SMILES CCC(C)(C)NC(NC#N)=Nc1cccnc1 |w:10.10| Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247651 ((+/-)-3-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2C(OC(=O)c2cccc(Cl)c2)C1O)C#N Show InChI InChI=1S/C19H16ClNO4/c1-19(2)17(22)16(14-8-11(10-21)6-7-15(14)25-19)24-18(23)12-4-3-5-13(20)9-12/h3-9,16-17,22H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247709 (4-chloro-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NC(=O)c2cnccc2Cl)[C@@H]1O)C#N |r| Show InChI InChI=1S/C18H16ClN3O3/c1-18(2)16(23)15(11-7-10(8-20)3-4-14(11)25-18)22-17(24)12-9-21-6-5-13(12)19/h3-7,9,15-16,23H,1-2H3,(H,22,24)/t15-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247798 ((3S,4R)-4-(6-chloro-3-oxo-3H-benzo[d]isoxazol-2-yl...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)C#N |r| Show InChI InChI=1S/C19H15ClN2O4/c1-19(2)17(23)16(13-7-10(9-21)3-6-14(13)25-19)22-18(24)12-5-4-11(20)8-15(12)26-22/h3-8,16-17,23H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247817 ((3S,4R)-2-(6-Benzenesulfonyl-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H20ClNO6S/c1-24(2)22(27)21(26-23(28)17-10-8-14(25)12-20(17)32-26)18-13-16(9-11-19(18)31-24)33(29,30)15-6-4-3-5-7-15/h3-13,21-22,27H,1-2H3/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247681 ((+/-)-4-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2C(NC(=O)c2ccc(Cl)cc2)C1O)C#N Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-9-11(10-21)3-8-15(14)25-19)22-18(24)12-4-6-13(20)7-5-12/h3-9,16-17,23H,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247707 (CHEMBL454166 | N-((3S,4R)-6-cyano-3-hydroxy-2,2-di...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NC(=O)c2ccc3OCOc3c2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C20H18N2O5/c1-20(2)18(23)17(13-7-11(9-21)3-5-14(13)27-20)22-19(24)12-4-6-15-16(8-12)26-10-25-15/h3-8,17-18,23H,10H2,1-2H3,(H,22,24)/t17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247834 ((3S,4R)-(5-Chloro-3-oxo-3H-benzo[d]isoxazol-2-yl)-...) Show SMILES CCN(CC)S(=O)(=O)c1ccc2OC(C)(C)[C@@H](O)[C@@H](c2c1)n1oc2ccc(Cl)cc2c1=O |r| Show InChI InChI=1S/C22H25ClN2O6S/c1-5-24(6-2)32(28,29)14-8-10-17-15(12-14)19(20(26)22(3,4)30-17)25-21(27)16-11-13(23)7-9-18(16)31-25/h7-12,19-20,26H,5-6H2,1-4H3/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	820	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247833 ((3S,4R)-6-Chloro-2-[3-hydroxy-2,2-dimethyl-6-(pipe...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)S(=O)(=O)N1CCCCC1 |r| Show InChI InChI=1S/C23H25ClN2O6S/c1-23(2)21(27)20(26-22(28)16-8-6-14(24)12-19(16)32-26)17-13-15(7-9-18(17)31-23)33(29,30)25-10-4-3-5-11-25/h6-9,12-13,20-21,27H,3-5,10-11H2,1-2H3/t20-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50010132 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxo-pyrrolidin...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCC1=O)C#N |r| Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247784 ((3S,4R)-6-Benzenesulfonyl-4-(5-chloro-benzo[d]-iso...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2noc3ccc(Cl)cc23)[C@@H]1O)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H21ClN2O5S/c1-24(2)22(28)21(26-23-18-12-14(25)8-10-20(18)32-27-23)17-13-16(9-11-19(17)31-24)33(29,30)15-6-4-3-5-7-15/h3-13,21-22,28H,1-2H3,(H,26,27)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247723 ((3S,4R)-4-[5-(4-Chloro-phenyl)-pyrazol-1-yl]-3-hyd...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1nccc1-c1ccc(Cl)cc1)C#N |r| Show InChI InChI=1S/C21H18ClN3O2/c1-21(2)20(26)19(16-11-13(12-23)3-8-18(16)27-21)25-17(9-10-24-25)14-4-6-15(22)7-5-14/h3-11,19-20,26H,1-2H3/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247710 (3-chloro-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NS(=O)(=O)c2cccc(Cl)c2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C18H17ClN2O4S/c1-18(2)17(22)16(14-8-11(10-20)6-7-15(14)25-18)21-26(23,24)13-5-3-4-12(19)9-13/h3-9,16-17,21-22H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247818 ((3S,4R)-2-(6-Benzenesulfonyl-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2ccc(Cl)cc2c1=O)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H20ClNO6S/c1-24(2)22(27)21(26-23(28)18-12-14(25)8-10-20(18)32-26)17-13-16(9-11-19(17)31-24)33(29,30)15-6-4-3-5-7-15/h3-13,21-22,27H,1-2H3/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247764 ((3S,4R)-4-[5-(4-Chloro-phenyl)-pyrazol-1-yl]-2,2-d...) Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1nccc1-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)18(24)17(14-11-21-9-8-16(14)25-19)23-15(7-10-22-23)12-3-5-13(20)6-4-12/h3-11,17-18,24H,1-2H3/t17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247860 ((3S,4R)-6-Chloro-2-[6-(3-fluoro-benzenesulfonyl)-3...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)S(=O)(=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C24H19ClFNO6S/c1-24(2)22(28)21(27-23(29)17-8-6-13(25)10-20(17)33-27)18-12-16(7-9-19(18)32-24)34(30,31)15-5-3-4-14(26)11-15/h3-12,21-22,28H,1-2H3/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247679 ((+)-3-chlorophenyl (3R,4S)-6-cyano-3-hydroxy-2,2-d...) Show SMILES CC1(C)Oc2ccc(cc2[C@H](NC(=O)c2cccc(Cl)c2)[C@H]1O)C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-8-11(10-21)6-7-15(14)25-19)22-18(24)12-4-3-5-13(20)9-12/h3-9,16-17,23H,1-2H3,(H,22,24)/t16-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247611 ((3S,4R)-4-(6-Chloro-4-oxo-1,4-dihydro-quinazolin-2...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2nc3ccc(Cl)cc3c(=O)[nH]2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C20H17ClN4O3/c1-20(2)17(26)16(13-7-10(9-22)3-6-15(13)28-20)24-19-23-14-5-4-11(21)8-12(14)18(27)25-19/h3-8,16-17,26H,1-2H3,(H2,23,24,25,27)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247799 ((3S,4R)-4-(5-chloro-3-oxobenzo[d]isoxazol-2(3H)-yl...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2ccc(Cl)cc2c1=O)C#N |r| Show InChI InChI=1S/C19H15ClN2O4/c1-19(2)17(23)16(12-7-10(9-21)3-5-14(12)25-19)22-18(24)13-8-11(20)4-6-15(13)26-22/h3-8,16-17,23H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247612 ((3S,4R)-4-(5-Ethoxy-benzothiazol-2-ylamino)-3-hydr...) Show SMILES CCOc1ccc2nc(S[C@H]3[C@H](O)C(C)(C)Oc4ccc(cc34)C#N)[nH]c2c1 |r| Show InChI InChI=1S/C21H21N3O3S/c1-4-26-13-6-7-15-16(10-13)24-20(23-15)28-18-14-9-12(11-22)5-8-17(14)27-21(2,3)19(18)25/h5-10,18-19,25H,4H2,1-3H3,(H,23,24)/t18-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247724 ((3S,4R)-4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-3-hy...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1ccnc1-c1ccc(Cl)cc1)C#N |r| Show InChI InChI=1S/C21H18ClN3O2/c1-21(2)19(26)18(16-11-13(12-23)3-8-17(16)27-21)25-10-9-24-20(25)14-4-6-15(22)7-5-14/h3-11,18-19,26H,1-2H3/t18-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247649 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(5-nitrobenzothia...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(cc3[nH]2)[N+]([O-])=O)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16N4O4S/c1-19(2)17(24)16(12-7-10(9-20)3-6-15(12)27-19)28-18-21-13-5-4-11(23(25)26)8-14(13)22-18/h3-8,16-17,24H,1-2H3,(H,21,22)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247861 ((3S,4R)-4-(5-Chloro-1,3-dioxo-1,3-dihydro-isoindol...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1C(=O)c2ccc(Cl)cc2C1=O)C#N |r| Show InChI InChI=1S/C20H15ClN2O4/c1-20(2)17(24)16(14-7-10(9-22)3-6-15(14)27-20)23-18(25)12-5-4-11(21)8-13(12)19(23)26/h3-8,16-17,24H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50240750 (()-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylprop...) Show SMILES CC(NC(NC#N)=Nc1ccncc1)C(C)(C)C |w:7.7| Show InChI InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.54E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247775 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(4-oxo-1,4-dihydr...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2nc3ccccc3c(=O)[nH]2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C20H18N4O3/c1-20(2)17(25)16(13-9-11(10-21)7-8-15(13)27-20)23-19-22-14-6-4-3-5-12(14)18(26)24-19/h3-9,16-17,25H,1-2H3,(H2,22,23,24,26)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247816 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(6-nitro-3-oxo-3H...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1sc2cc(ccc2c1=O)[N+]([O-])=O)C#N |r| Show InChI InChI=1S/C19H15N3O5S/c1-19(2)17(23)16(13-7-10(9-20)3-6-14(13)27-19)21-18(24)12-5-4-11(22(25)26)8-15(12)28-21/h3-8,16-17,23H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247763 ((3S,4R)-4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-...) Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1ccnc1-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)17(24)16(14-11-21-8-7-15(14)25-19)23-10-9-22-18(23)12-3-5-13(20)6-4-12/h3-11,16-17,24H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247907 ((3S,4R)-4-(1,3-Dioxo-1,3-dihydro-pyrrolo[3,4-c]pyr...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1C(=O)c2ccncc2C1=O)C#N |r| Show InChI InChI=1S/C19H15N3O4/c1-19(2)16(23)15(12-7-10(8-20)3-4-14(12)26-19)22-17(24)11-5-6-21-9-13(11)18(22)25/h3-7,9,15-16,23H,1-2H3/t15-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.04E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247779 ((3S,4R)-4-(6-Chloro-benzo[d]isoxazol-3-ylamino)-3-...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2noc3cc(Cl)ccc23)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16ClN3O3/c1-19(2)17(24)16(13-7-10(9-21)3-6-14(13)25-19)22-18-12-5-4-11(20)8-15(12)26-23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.18E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247836 ((3S,4R)-2-(6-Benzoyl-3-hydroxy-2,2-dimethyl-chroma...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H20ClNO5/c1-25(2)23(29)21(27-24(30)17-10-9-16(26)13-20(17)32-27)18-12-15(8-11-19(18)31-25)22(28)14-6-4-3-5-7-14/h3-13,21,23,29H,1-2H3/t21-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.45E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247783 ((3S,4R)-4-(5-Chloro-1H-indazol-3-ylamino)-3-hydrox...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2n[nH]c3ccc(Cl)cc23)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H17ClN4O2/c1-19(2)17(25)16(13-7-10(9-21)3-6-15(13)26-19)22-18-12-8-11(20)4-5-14(12)23-24-18/h3-8,16-17,25H,1-2H3,(H2,22,23,24)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.85E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247797 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(3-oxo-3H-benzo[d...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2ccccc2c1=O)C#N |r| Show InChI InChI=1S/C19H16N2O4/c1-19(2)17(22)16(13-9-11(10-20)7-8-14(13)24-19)21-18(23)12-5-3-4-6-15(12)25-21/h3-9,16-17,22H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.94E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247708 (3,4-dichloro-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dime...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NC(=O)c2ccc(Cl)c(Cl)c2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16Cl2N2O3/c1-19(2)17(24)16(12-7-10(9-22)3-6-15(12)26-19)23-18(25)11-4-5-13(20)14(21)8-11/h3-8,16-17,24H,1-2H3,(H,23,25)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.06E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247858 ((3S,4R)-6-Chloro-[2-hydroxy-6-(4-methoxy-benzenesu...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccc2OC(C)(C)[C@@H](O)[C@@H](c2c1)n1oc2cc(Cl)ccc2c1=O |r| Show InChI InChI=1S/C25H22ClNO7S/c1-25(2)23(28)22(27-24(29)18-10-4-14(26)12-21(18)34-27)19-13-17(9-11-20(19)33-25)35(30,31)16-7-5-15(32-3)6-8-16/h4-13,22-23,28H,1-3H3/t22-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.33E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247725 ((3S,4R)-4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-3-hy...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1cncc1-c1ccc(Cl)cc1)C#N |r| Show InChI InChI=1S/C21H18ClN3O2/c1-21(2)20(26)19(16-9-13(10-23)3-8-18(16)27-21)25-12-24-11-17(25)14-4-6-15(22)7-5-14/h3-9,11-12,19-20,26H,1-2H3/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.45E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247785 ((3S,4R)-4-(5-Chloro-benzo[d]isoxazol-3-ylamino)-6-...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2noc3ccc(Cl)cc23)[C@@H]1O)S(=O)(=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C24H20ClFN2O5S/c1-24(2)22(29)21(27-23-18-10-13(25)6-8-20(18)33-28-23)17-12-16(7-9-19(17)32-24)34(30,31)15-5-3-4-14(26)11-15/h3-12,21-22,29H,1-2H3,(H,27,28)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.77E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247777 ((3S,4R)-4-(6-Chloro-benzo[d]isoxazol-3-yloxy)-3-hy...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Oc2noc3cc(Cl)ccc23)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H15ClN2O4/c1-19(2)17(23)16(13-7-10(9-21)3-6-14(13)25-19)24-18-12-5-4-11(20)8-15(12)26-22-18/h3-8,16-17,23H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247859 ((3S,4R)-6-Chloro-2-[6-(4-chloro-benzenesulfonyl)-3...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O)S(=O)(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H19Cl2NO6S/c1-24(2)22(28)21(27-23(29)17-9-5-14(26)11-20(17)33-27)18-12-16(8-10-19(18)32-24)34(30,31)15-6-3-13(25)4-7-15/h3-12,21-22,28H,1-2H3/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.99E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247613 ((3S,4R)-4-(5-Fluoro-benzothiazol-2-ylamino)-3-hydr...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(F)cc3[nH]2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16FN3O2S/c1-19(2)17(24)16(12-7-10(9-21)3-6-15(12)25-19)26-18-22-13-5-4-11(20)8-14(13)23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.44E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247835 ((3S,4R)-6-Chloro-2-(6,7-dichloro-3-hydroxy-2,2-dim...) Show SMILES CC1(C)Oc2cc(Cl)c(Cl)cc2[C@H]([C@@H]1O)n1oc2cc(Cl)ccc2c1=O |r| Show InChI InChI=1S/C18H14Cl3NO4/c1-18(2)16(23)15(10-6-11(20)12(21)7-13(10)25-18)22-17(24)9-4-3-8(19)5-14(9)26-22/h3-7,15-16,23H,1-2H3/t15-,16+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247762 ((3S,4R)-2,2-Dimethyl-4-(2-phenyl-imidazol-1-yl)-3,...) Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1ccnc1-c1ccccc1 |r| Show InChI InChI=1S/C19H19N3O2/c1-19(2)17(23)16(14-12-20-9-8-15(14)24-19)22-11-10-21-18(22)13-6-4-3-5-7-13/h3-12,16-17,23H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247727 ((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-phenyl-imidazo...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1ccnc1-c1ccccc1)C#N |r| Show InChI InChI=1S/C21H19N3O2/c1-21(2)19(25)18(16-12-14(13-22)8-9-17(16)26-21)24-11-10-23-20(24)15-6-4-3-5-7-15/h3-12,18-19,25H,1-2H3/t18-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247765 ((3S,4R) 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-...) Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1cncc1-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)18(24)17(14-9-21-8-7-16(14)25-19)23-11-22-10-15(23)12-3-5-13(20)6-4-12/h3-11,17-18,24H,1-2H3/t17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247815 ((3S,4R)-3-hydroxy-2,2-dimethyl-4-(3-oxobenzo[d]iso...) Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1sc2ccccc2c1=O)C#N |r| Show InChI InChI=1S/C19H16N2O3S/c1-19(2)17(22)16(13-9-11(10-20)7-8-14(13)24-19)21-18(23)12-5-3-4-6-15(12)25-21/h3-9,16-17,22H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247776 ((3S,4R)-4-(5-Chloro-1H-benzoimidazol-2-ylsulfanyl)...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(Cl)cc3[nH]2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16ClN3O2S/c1-19(2)17(24)16(12-7-10(9-21)3-6-15(12)25-19)26-18-22-13-5-4-11(20)8-14(13)23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247778 ((3S,4R)-4-(Benzo[d]isothiazol-3-yloxy)-3-hydroxy-2...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Oc2nsc3ccccc23)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16N2O3S/c1-19(2)17(22)16(13-9-11(10-20)7-8-14(13)24-19)23-18-12-5-3-4-6-15(12)25-21-18/h3-9,16-17,22H,1-2H3/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247650 ((3S,4R)-4-(5-Chloro-benzooxazol-2-ylamino)-3-hydro...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2nc3cc(Cl)ccc3o2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H16ClN3O3/c1-19(2)17(24)16(12-7-10(9-21)3-5-14(12)26-19)23-18-22-13-8-11(20)4-6-15(13)25-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 9 (Homo sapiens (Human))	BDBM50247711 (CHEMBL508720 | N-((3S,4R)-6-cyano-3-hydroxy-2,2-di...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NP(C)(=O)c2ccccc2)[C@@H]1O)C#N |r| Show InChI InChI=1S/C19H21N2O3P/c1-19(2)18(22)17(15-11-13(12-20)9-10-16(15)24-19)21-25(3,23)14-7-5-4-6-8-14/h4-11,17-18,22H,1-3H3,(H,21,23)/t17-,18+,25?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 56 total )  |  Next  |  Last  >>

Jump to: