BindingDB PrimarySearch

Found 8 hits of ec50 data for polymerid = 50000676
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50322368 ((S)-5-((S)-1-((S)-2-((S)-1-((S)-1-((S)-1-carboxy-3...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Medical University of South Carolina Campus Curated by ChEMBL					Assay Description Binding affinity to human NTR2 by gamma counting				J Med Chem 53: 4623-32 (2010) Article DOI: 10.1021/jm100092s BindingDB Entry DOI: 10.7270/Q2DF6RDK
					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50130880 (CHEMBL407196 \| NT(1-13) \| neurotensin \| pGlu-Leu-T...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50342251 ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-2-((S)-2-amino-5-g...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50342244 ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-6-amino-2-((S)-2,6...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50342245 ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-2-((S)-2,6-diamino...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50342248 ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-6-amino-2-((S)-2-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit...				J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50444943 (CHEMBL3099773) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assay				Bioorg Med Chem Lett 24: 262-7 (2013) Article DOI: 10.1016/j.bmcl.2013.11.026 BindingDB Entry DOI: 10.7270/Q2NV9KQ0
					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50248035 ((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assay				Bioorg Med Chem Lett 24: 262-7 (2013) Article DOI: 10.1016/j.bmcl.2013.11.026 BindingDB Entry DOI: 10.7270/Q2NV9KQ0
					More data for this Ligand-Target Pair